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The map label for this gene is yycG [H]

Identifier: 116493524

GI number: 116493524

Start: 1774775

End: 1776622

Strand: Reverse

Name: yycG [H]

Synonym: PEPE_1796

Alternate gene names: 116493524

Gene position: 1776622-1774775 (Counterclockwise)

Preceding gene: 116493525

Following gene: 116493523

Centisome position: 96.96

GC content: 38.04

Gene sequence:

>1848_bases
ATGAATAAACGAACGAATTTTTTCAAATCAATTAACTTTAAAATAGCTCTAGTGTTTGCAATGTTGCTAGTCGTAACGTT
GGAAGTCGTTGGAGTTATTTTTGTGCGACAACTTGAAACACAAAACTTGAATCAATTTAAAACTCAAGTTCAACTACAAC
CTTATGTTGAAAATGAGATTAGTACGCAATTAGAACGTGCTAATACGAAGAGCGCTAACTCACAAATATCCGATATCATT
GGAAACATCAATAATCAAAATATCACGGAAATTCGAGTGATTGATGCCAAGGGTGTTATTCGGGGAACGAGTAATAGTAC
TAACCAGAATATTGTTGGTCAAAAGACAACGGATCGCAATGTTAAGGATGTAATCTACAATACGCGAACCTATCAACAAG
TTTCGTACAATAAAACCACTAACACGCGTTATTTTGTTTCAATTGTTCCTTTAATTAACACTGCAGGAGCAACCAACAAC
TTGACGGGTGTTGTTTATATACGCGCTAATCTAGAATCGGTATATCAGAATGTTAATAATATTACGTTAATTTTCGTAGT
AGCTGCTTTAATTGCGATTACAATTGGACTAATTTTAGCCGTTTTAATTTCCCGAGCGATTACCCGTCCCATCGAAGAAA
TGCGGCAACGAACGATTCAAATCGCCCGTGGAGATTATTCTGGTCAGGTTCAGATTTATGGTGATGATGAACTTGGCCAA
CTAGCAGAAGCTGTTAATGAACTTTCTGTACGGGTAGAAGAATCTCAGGAATCGACTGAATCTGAACGGCGGCGTCTTGA
TTCCGTCTTGGGCTATATGACTGATGGGGTGCTGGCGACAGATCGACGCGGACGAATAACCATCGTTAATGAAATGGCAA
CGGATTTCTTGAATCTTGAGAATGACCAAATCGTTGGGAAATCAATTTTAGACATTCTCGATTTACGAGGAACGTTTACT
TTACGGGACTTACTTGAAAATCAAGAGCAGGTTGTTTTAGATCTTTCCGATGATGACCAAGATTTAATTTTACATGCTTC
ATTTGCCTTAATTCAGCGTGAATCAGGCTTTATTAGTGGTCTGGTTTGTGTTTTACATGATGTTACTGAACAGCAAAAAA
TTGATCAAGACCGAAAACGATTTGTTTCTAACGTTTCGCATGAATTGCGGACACCTTTGACTAGTATGAAGAGTTATATT
GAAGCATTGGTTGAAGGAGCCTGGAAAGATCCAGAAGTGGCCCCTAATTTCTTGAAGGTTACGCAAGAAGAAACGGATCG
AATGATGCGGATGATTAATGATTTACTAAATTTATCACGTATGGATTTAGGAACGGCTAGATTGGAACGTGAATATGTTA
ACCTAAATGAATTATTCAACCATATTTTGGACCGTTTCGATATGATTCTGAAAAATAGTGATAAACCAGATAAAAATTAC
TCTATTAAACGCGACTTTACGCGTCGTGATATTTGGGTTGAAGTTGATACAGATAAAATTCAACAAGTATTGGATAATAT
CATGAATAATGCGATTAAATATTCTCCAGATGGGGGGATTATTACCTGTCGGCTATTAGAGACCCACAATCACGTGATTA
TGAGTATTACAGATCAAGGTTTGGGAATTCCAAAGGATTCAATTAGCCACATTTTCGATCGTTTTTACCGCGTGGATAAG
GCTCGTTCACGGGCTCAAGGTGGTACTGGTTTGGGATTGGCGATTTCAAAAGAAGTTATCCAACTTCATGGTGGTCGAAT
TTGGGTCGAAAGTCGCGAAGGTGAAGGATCTACCTTCTACATTTCACTTCCATATGAACCCTTTGAGGAAGGAGATACTT
GGGAATAA

Upstream 100 bases:

>100_bases
ACCCCAGGAAACCCTCAAATTTTGGTTACACGTCGTGGAGTGGGATACTATTTACGTAATCCAGAAAATGATTAATTAAT
TCAGGATTTTTGGAGACTAA

Downstream 100 bases:

>100_bases
TGAAAGATACTAAAACGCGTAAAATTGTCCGACATGTCATTTTATTAATATTAGCGCTAACTAGCATCGTGCTTTCATGG
GTAATTTGGACTAACCCGGC

Product: PAS/PAC sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 615; Mature: 615

Protein sequence:

>615_residues
MNKRTNFFKSINFKIALVFAMLLVVTLEVVGVIFVRQLETQNLNQFKTQVQLQPYVENEISTQLERANTKSANSQISDII
GNINNQNITEIRVIDAKGVIRGTSNSTNQNIVGQKTTDRNVKDVIYNTRTYQQVSYNKTTNTRYFVSIVPLINTAGATNN
LTGVVYIRANLESVYQNVNNITLIFVVAALIAITIGLILAVLISRAITRPIEEMRQRTIQIARGDYSGQVQIYGDDELGQ
LAEAVNELSVRVEESQESTESERRRLDSVLGYMTDGVLATDRRGRITIVNEMATDFLNLENDQIVGKSILDILDLRGTFT
LRDLLENQEQVVLDLSDDDQDLILHASFALIQRESGFISGLVCVLHDVTEQQKIDQDRKRFVSNVSHELRTPLTSMKSYI
EALVEGAWKDPEVAPNFLKVTQEETDRMMRMINDLLNLSRMDLGTARLEREYVNLNELFNHILDRFDMILKNSDKPDKNY
SIKRDFTRRDIWVEVDTDKIQQVLDNIMNNAIKYSPDGGIITCRLLETHNHVIMSITDQGLGIPKDSISHIFDRFYRVDK
ARSRAQGGTGLGLAISKEVIQLHGGRIWVESREGEGSTFYISLPYEPFEEGDTWE

Sequences:

>Translated_615_residues
MNKRTNFFKSINFKIALVFAMLLVVTLEVVGVIFVRQLETQNLNQFKTQVQLQPYVENEISTQLERANTKSANSQISDII
GNINNQNITEIRVIDAKGVIRGTSNSTNQNIVGQKTTDRNVKDVIYNTRTYQQVSYNKTTNTRYFVSIVPLINTAGATNN
LTGVVYIRANLESVYQNVNNITLIFVVAALIAITIGLILAVLISRAITRPIEEMRQRTIQIARGDYSGQVQIYGDDELGQ
LAEAVNELSVRVEESQESTESERRRLDSVLGYMTDGVLATDRRGRITIVNEMATDFLNLENDQIVGKSILDILDLRGTFT
LRDLLENQEQVVLDLSDDDQDLILHASFALIQRESGFISGLVCVLHDVTEQQKIDQDRKRFVSNVSHELRTPLTSMKSYI
EALVEGAWKDPEVAPNFLKVTQEETDRMMRMINDLLNLSRMDLGTARLEREYVNLNELFNHILDRFDMILKNSDKPDKNY
SIKRDFTRRDIWVEVDTDKIQQVLDNIMNNAIKYSPDGGIITCRLLETHNHVIMSITDQGLGIPKDSISHIFDRFYRVDK
ARSRAQGGTGLGLAISKEVIQLHGGRIWVESREGEGSTFYISLPYEPFEEGDTWE
>Mature_615_residues
MNKRTNFFKSINFKIALVFAMLLVVTLEVVGVIFVRQLETQNLNQFKTQVQLQPYVENEISTQLERANTKSANSQISDII
GNINNQNITEIRVIDAKGVIRGTSNSTNQNIVGQKTTDRNVKDVIYNTRTYQQVSYNKTTNTRYFVSIVPLINTAGATNN
LTGVVYIRANLESVYQNVNNITLIFVVAALIAITIGLILAVLISRAITRPIEEMRQRTIQIARGDYSGQVQIYGDDELGQ
LAEAVNELSVRVEESQESTESERRRLDSVLGYMTDGVLATDRRGRITIVNEMATDFLNLENDQIVGKSILDILDLRGTFT
LRDLLENQEQVVLDLSDDDQDLILHASFALIQRESGFISGLVCVLHDVTEQQKIDQDRKRFVSNVSHELRTPLTSMKSYI
EALVEGAWKDPEVAPNFLKVTQEETDRMMRMINDLLNLSRMDLGTARLEREYVNLNELFNHILDRFDMILKNSDKPDKNY
SIKRDFTRRDIWVEVDTDKIQQVLDNIMNNAIKYSPDGGIITCRLLETHNHVIMSITDQGLGIPKDSISHIFDRFYRVDK
ARSRAQGGTGLGLAISKEVIQLHGGRIWVESREGEGSTFYISLPYEPFEEGDTWE

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH and ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF [H]

COG id: COG5002

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=397, Percent_Identity=29.2191435768262, Blast_Score=143, Evalue=3e-35,
Organism=Escherichia coli, GI1788393, Length=240, Percent_Identity=29.5833333333333, Blast_Score=116, Evalue=4e-27,
Organism=Escherichia coli, GI1788549, Length=396, Percent_Identity=27.7777777777778, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1790436, Length=227, Percent_Identity=34.3612334801762, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1786783, Length=225, Percent_Identity=30.2222222222222, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI145693157, Length=260, Percent_Identity=28.0769230769231, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1788713, Length=264, Percent_Identity=26.5151515151515, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1790346, Length=248, Percent_Identity=30.241935483871, Blast_Score=99, Evalue=9e-22,
Organism=Escherichia coli, GI1789149, Length=241, Percent_Identity=29.8755186721992, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI1790551, Length=253, Percent_Identity=29.6442687747036, Blast_Score=95, Evalue=2e-20,
Organism=Escherichia coli, GI1786912, Length=244, Percent_Identity=29.0983606557377, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI1790861, Length=209, Percent_Identity=28.7081339712919, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI48994928, Length=255, Percent_Identity=25.4901960784314, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1787894, Length=232, Percent_Identity=28.0172413793103, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI87082128, Length=237, Percent_Identity=25.3164556962025, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI87081816, Length=240, Percent_Identity=26.25, Blast_Score=80, Evalue=5e-16,
Organism=Escherichia coli, GI1790300, Length=236, Percent_Identity=28.8135593220339, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1789403, Length=207, Percent_Identity=27.536231884058, Blast_Score=71, Evalue=3e-13,
Organism=Escherichia coli, GI1788279, Length=232, Percent_Identity=26.7241379310345, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1787374, Length=219, Percent_Identity=26.9406392694064, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1789808, Length=239, Percent_Identity=25.1046025104602, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 69902; Mature: 69902

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKRTNFFKSINFKIALVFAMLLVVTLEVVGVIFVRQLETQNLNQFKTQVQLQPYVENEI
CCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHEEECCHHHHHH
STQLERANTKSANSQISDIIGNINNQNITEIRVIDAKGVIRGTSNSTNQNIVGQKTTDRN
HHHHHHHCCCCCHHHHHHHHCCCCCCCEEEEEEEECCCEEECCCCCCCCCCCCCCCCCCC
VKDVIYNTRTYQQVSYNKTTNTRYFVSIVPLINTAGATNNLTGVVYIRANLESVYQNVNN
HHHHHCCCCHHEEEEECCCCCCEEEEEEEEHHHCCCCCCCCEEEEEEEECHHHHHHCCCC
ITLIFVVAALIAITIGLILAVLISRAITRPIEEMRQRTIQIARGDYSGQVQIYGDDELGQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHH
LAEAVNELSVRVEESQESTESERRRLDSVLGYMTDGVLATDRRGRITIVNEMATDFLNLE
HHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCEEEEHHHHHHHHCCC
NDQIVGKSILDILDLRGTFTLRDLLENQEQVVLDLSDDDQDLILHASFALIQRESGFISG
CCCHHHHHHHHHHHCCCCHHHHHHHCCCCEEEEECCCCCCCEEEEHHHHHHHHCCCHHHH
LVCVLHDVTEQQKIDQDRKRFVSNVSHELRTPLTSMKSYIEALVEGAWKDPEVAPNFLKV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCHHHHH
TQEETDRMMRMINDLLNLSRMDLGTARLEREYVNLNELFNHILDRFDMILKNSDKPDKNY
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCC
SIKRDFTRRDIWVEVDTDKIQQVLDNIMNNAIKYSPDGGIITCRLLETHNHVIMSITDQG
CCCCCCCCCEEEEEECHHHHHHHHHHHHHCCEEECCCCCEEEEEEEECCCEEEEEEECCC
LGIPKDSISHIFDRFYRVDKARSRAQGGTGLGLAISKEVIQLHGGRIWVESREGEGSTFY
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCEEE
ISLPYEPFEEGDTWE
EECCCCCCCCCCCCC
>Mature Secondary Structure
MNKRTNFFKSINFKIALVFAMLLVVTLEVVGVIFVRQLETQNLNQFKTQVQLQPYVENEI
CCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHEEECCHHHHHH
STQLERANTKSANSQISDIIGNINNQNITEIRVIDAKGVIRGTSNSTNQNIVGQKTTDRN
HHHHHHHCCCCCHHHHHHHHCCCCCCCEEEEEEEECCCEEECCCCCCCCCCCCCCCCCCC
VKDVIYNTRTYQQVSYNKTTNTRYFVSIVPLINTAGATNNLTGVVYIRANLESVYQNVNN
HHHHHCCCCHHEEEEECCCCCCEEEEEEEEHHHCCCCCCCCEEEEEEEECHHHHHHCCCC
ITLIFVVAALIAITIGLILAVLISRAITRPIEEMRQRTIQIARGDYSGQVQIYGDDELGQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHH
LAEAVNELSVRVEESQESTESERRRLDSVLGYMTDGVLATDRRGRITIVNEMATDFLNLE
HHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCEEEEHHHHHHHHCCC
NDQIVGKSILDILDLRGTFTLRDLLENQEQVVLDLSDDDQDLILHASFALIQRESGFISG
CCCHHHHHHHHHHHCCCCHHHHHHHCCCCEEEEECCCCCCCEEEEHHHHHHHHCCCHHHH
LVCVLHDVTEQQKIDQDRKRFVSNVSHELRTPLTSMKSYIEALVEGAWKDPEVAPNFLKV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCHHHHH
TQEETDRMMRMINDLLNLSRMDLGTARLEREYVNLNELFNHILDRFDMILKNSDKPDKNY
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCC
SIKRDFTRRDIWVEVDTDKIQQVLDNIMNNAIKYSPDGGIITCRLLETHNHVIMSITDQG
CCCCCCCCCEEEEEECHHHHHHHHHHHHHCCEEECCCCCEEEEEEEECCCEEEEEEECCC
LGIPKDSISHIFDRFYRVDKARSRAQGGTGLGLAISKEVIQLHGGRIWVESREGEGSTFY
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCEEE
ISLPYEPFEEGDTWE
EECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 9829949; 10878122; 11758928 [H]