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The map label for this gene is yycF [H]

Identifier: 116493525

GI number: 116493525

Start: 1776648

End: 1777349

Strand: Reverse

Name: yycF [H]

Synonym: PEPE_1797

Alternate gene names: 116493525

Gene position: 1777349-1776648 (Counterclockwise)

Preceding gene: 116493526

Following gene: 116493524

Centisome position: 97.0

GC content: 38.89

Gene sequence:

>702_bases
ATGCCAAAGATTTTAGTAGTAGATGATGAAAAACCGATTTCTGACATAGTTAAGTTTAATTTAGATAAAGAAGGATACGA
TGTAGTTACTGCATATGATGGTGAGGAAGCTCTTGCCCAAGTCGAAGAAGAAAAGCCCGACTTGATTCTGCTTGATTTGA
TGTTACCAAAAATTGATGGATTAGAGGTTGCGCGCCAAGTAAGAGCAAAACATAATATTCCAATCATCATGGTAACAGCT
AAGGATTCAGAATTAGACAAGGTTGTTGGACTTGAGCTTGGTGCGGATGATTACGTTACTAAGCCATTTTCTAACCGTGA
ACTAGTGGCGCGGGTAAAAGCCAACCTTCGTCGTCAGGATCAATTGCAACAAGATGATGAGACTGTTAAAAATAATATTA
AAATTGGACCTTTAGTGATTAATTCAGATTCATACTCAGTGACTCGTGATGGGATGCAATTAGATTTGACCCATCGTGAA
TTTGAACTTTTACATTATTTGGCTCAACATACGGGCCAAGTGATGACTCGTGAACATCTTCTTCAAACGGTTTGGGGATA
TGATTATTTTGGGGACGTTCGTACAGTGGATGTTACCGTACGTCGTTTGCGCGAAAAAATTGAAGAAACCCCAGGAAACC
CTCAAATTTTGGTTACACGTCGTGGAGTGGGATACTATTTACGTAATCCAGAAAATGATTAA

Upstream 100 bases:

>100_bases
TTTTAGTGTATATGTTATAATTAACCAAGATTAATGGATTGGACCATTTTTATCAGGAATGCATACCTGATGGCAGATAA
ATCTTCCAAGGAGGGCTAAC

Downstream 100 bases:

>100_bases
TTAATTCAGGATTTTTGGAGACTAAATGAATAAACGAACGAATTTTTTCAAATCAATTAACTTTAAAATAGCTCTAGTGT
TTGCAATGTTGCTAGTCGTA

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 233; Mature: 232

Protein sequence:

>233_residues
MPKILVVDDEKPISDIVKFNLDKEGYDVVTAYDGEEALAQVEEEKPDLILLDLMLPKIDGLEVARQVRAKHNIPIIMVTA
KDSELDKVVGLELGADDYVTKPFSNRELVARVKANLRRQDQLQQDDETVKNNIKIGPLVINSDSYSVTRDGMQLDLTHRE
FELLHYLAQHTGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEETPGNPQILVTRRGVGYYLRNPEND

Sequences:

>Translated_233_residues
MPKILVVDDEKPISDIVKFNLDKEGYDVVTAYDGEEALAQVEEEKPDLILLDLMLPKIDGLEVARQVRAKHNIPIIMVTA
KDSELDKVVGLELGADDYVTKPFSNRELVARVKANLRRQDQLQQDDETVKNNIKIGPLVINSDSYSVTRDGMQLDLTHRE
FELLHYLAQHTGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEETPGNPQILVTRRGVGYYLRNPEND
>Mature_232_residues
PKILVVDDEKPISDIVKFNLDKEGYDVVTAYDGEEALAQVEEEKPDLILLDLMLPKIDGLEVARQVRAKHNIPIIMVTAK
DSELDKVVGLELGADDYVTKPFSNRELVARVKANLRRQDQLQQDDETVKNNIKIGPLVINSDSYSVTRDGMQLDLTHREF
ELLHYLAQHTGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEETPGNPQILVTRRGVGYYLRNPEND

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI2367329, Length=229, Percent_Identity=43.2314410480349, Blast_Score=170, Evalue=7e-44,
Organism=Escherichia coli, GI1786599, Length=226, Percent_Identity=42.0353982300885, Blast_Score=169, Evalue=1e-43,
Organism=Escherichia coli, GI1788394, Length=229, Percent_Identity=41.9213973799127, Blast_Score=161, Evalue=3e-41,
Organism=Escherichia coli, GI87082012, Length=223, Percent_Identity=37.6681614349776, Blast_Score=158, Evalue=2e-40,
Organism=Escherichia coli, GI1789809, Length=225, Percent_Identity=38.6666666666667, Blast_Score=157, Evalue=5e-40,
Organism=Escherichia coli, GI1790863, Length=228, Percent_Identity=37.719298245614, Blast_Score=150, Evalue=5e-38,
Organism=Escherichia coli, GI1786784, Length=231, Percent_Identity=36.3636363636364, Blast_Score=147, Evalue=5e-37,
Organism=Escherichia coli, GI1790860, Length=232, Percent_Identity=36.6379310344828, Blast_Score=144, Evalue=4e-36,
Organism=Escherichia coli, GI1787229, Length=230, Percent_Identity=36.0869565217391, Blast_Score=139, Evalue=1e-34,
Organism=Escherichia coli, GI1786911, Length=225, Percent_Identity=34.2222222222222, Blast_Score=138, Evalue=3e-34,
Organism=Escherichia coli, GI145693140, Length=231, Percent_Identity=35.0649350649351, Blast_Score=127, Evalue=8e-31,
Organism=Escherichia coli, GI1790552, Length=235, Percent_Identity=35.7446808510638, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1789402, Length=226, Percent_Identity=30.9734513274336, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1787375, Length=225, Percent_Identity=32.4444444444444, Blast_Score=107, Evalue=6e-25,
Organism=Escherichia coli, GI1790299, Length=123, Percent_Identity=34.1463414634146, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1788550, Length=161, Percent_Identity=26.7080745341615, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1790437, Length=101, Percent_Identity=37.6237623762376, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26700; Mature: 26569

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKILVVDDEKPISDIVKFNLDKEGYDVVTAYDGEEALAQVEEEKPDLILLDLMLPKIDG
CCEEEEEECCCCHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHCCCCEEEEEECCCCCCH
LEVARQVRAKHNIPIIMVTAKDSELDKVVGLELGADDYVTKPFSNRELVARVKANLRRQD
HHHHHHHHHHCCCCEEEEEECCCCCHHHHEEEECCCCCCCCCCCCHHHHHHHHHHHHHHH
QLQQDDETVKNNIKIGPLVINSDSYSVTRDGMQLDLTHREFELLHYLAQHTGQVMTREHL
HHHHHHHHHHCCCEECEEEECCCCCEEECCCEEEEECHHHHHHHHHHHHHHHHHHHHHHH
LQTVWGYDYFGDVRTVDVTVRRLREKIEETPGNPQILVTRRGVGYYLRNPEND
HHHHHCCCCCCCCEEHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEECCCCCC
>Mature Secondary Structure 
PKILVVDDEKPISDIVKFNLDKEGYDVVTAYDGEEALAQVEEEKPDLILLDLMLPKIDG
CEEEEEECCCCHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHCCCCEEEEEECCCCCCH
LEVARQVRAKHNIPIIMVTAKDSELDKVVGLELGADDYVTKPFSNRELVARVKANLRRQD
HHHHHHHHHHCCCCEEEEEECCCCCHHHHEEEECCCCCCCCCCCCHHHHHHHHHHHHHHH
QLQQDDETVKNNIKIGPLVINSDSYSVTRDGMQLDLTHREFELLHYLAQHTGQVMTREHL
HHHHHHHHHHCCCEECEEEECCCCCEEECCCEEEEECHHHHHHHHHHHHHHHHHHHHHHH
LQTVWGYDYFGDVRTVDVTVRRLREKIEETPGNPQILVTRRGVGYYLRNPEND
HHHHHCCCCCCCCEEHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]