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The map label for this gene is desR [H]

Identifier: 116493461

GI number: 116493461

Start: 1710184

End: 1710759

Strand: Reverse

Name: desR [H]

Synonym: PEPE_1733

Alternate gene names: 116493461

Gene position: 1710759-1710184 (Counterclockwise)

Preceding gene: 116493462

Following gene: 116493459

Centisome position: 93.36

GC content: 34.03

Gene sequence:

>576_bases
ATGTTAAATACTGCATTAAGTCAGCTATTAAATTTAGAAGATAATTTAGAAGTTTTAGGATCGGCAACCAATGGAAAACA
CGCATTAGCAGAAATCCAACGACTCCAACCAAATGTGGCAATTTTAGATATTGAAATGCCCATGATGTCGGGACTAGAAG
TTGCAGAAGTTTTACATGACAAGCAACTTGCTACTAAAGTAATTATTTTAACTACATTTGCTCAAAAGACTTATTTTGAA
AAAGCAGTTGAAGTAGAAGTAGCTGGATATTTATTAAAAGATAGTCCAAGTGATGATTTGATTGAAACTATCAATAAAGT
GATGATGGGACGCACAGTGTATGACCCAGAATTAGTAGTCACAGCCTTATCATCAAATAAAAATCCTTTATCCGAGCGTG
AAATGTCAGTTTTAAAGGCTGCAGTTAGTGGGGATGCAACTAAAGTAATGGCTCAAAAACTGTTTTTATCTGAGGGAACG
GTCCGTAATTATTTATCAGCAATTTTTAGTAAGTTAGGGGTTCATAACCGACTTGAAGCCATTGAAGTTGCTAAGAAAAA
TAAATGGATAAATTAA

Upstream 100 bases:

>100_bases
GTGAATTTGATATTCAACAAAATAAAATAGGAACGCAAGTTTCCTTTAACTTACCAGAGGAGTAACGATGATAACTTTAT
ATCTCGCAGAAGACCAAAGC

Downstream 100 bases:

>100_bases
AAAAGTTGCGACAAAAGGTAGTTTGAGTTCTCATAGCTATACGCTTAAACTCAGCCTTTTGTCACAACTTTTTATTTACG
TTTTAACTTAACTACTGCTT

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 191; Mature: 191

Protein sequence:

>191_residues
MLNTALSQLLNLEDNLEVLGSATNGKHALAEIQRLQPNVAILDIEMPMMSGLEVAEVLHDKQLATKVIILTTFAQKTYFE
KAVEVEVAGYLLKDSPSDDLIETINKVMMGRTVYDPELVVTALSSNKNPLSEREMSVLKAAVSGDATKVMAQKLFLSEGT
VRNYLSAIFSKLGVHNRLEAIEVAKKNKWIN

Sequences:

>Translated_191_residues
MLNTALSQLLNLEDNLEVLGSATNGKHALAEIQRLQPNVAILDIEMPMMSGLEVAEVLHDKQLATKVIILTTFAQKTYFE
KAVEVEVAGYLLKDSPSDDLIETINKVMMGRTVYDPELVVTALSSNKNPLSEREMSVLKAAVSGDATKVMAQKLFLSEGT
VRNYLSAIFSKLGVHNRLEAIEVAKKNKWIN
>Mature_191_residues
MLNTALSQLLNLEDNLEVLGSATNGKHALAEIQRLQPNVAILDIEMPMMSGLEVAEVLHDKQLATKVIILTTFAQKTYFE
KAVEVEVAGYLLKDSPSDDLIETINKVMMGRTVYDPELVVTALSSNKNPLSEREMSVLKAAVSGDATKVMAQKLFLSEGT
VRNYLSAIFSKLGVHNRLEAIEVAKKNKWIN

Specific function: Member of the two-component regulatory system desR/desK, responsible for cold induction of the des gene coding for the Delta5 acyl-lipid desaturase [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790102, Length=191, Percent_Identity=31.9371727748691, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1788712, Length=189, Percent_Identity=25.9259259259259, Blast_Score=81, Evalue=4e-17,
Organism=Escherichia coli, GI1786747, Length=161, Percent_Identity=29.8136645962733, Blast_Score=76, Evalue=1e-15,
Organism=Escherichia coli, GI1788521, Length=189, Percent_Identity=31.2169312169312, Blast_Score=74, Evalue=5e-15,
Organism=Escherichia coli, GI1787473, Length=190, Percent_Identity=28.4210526315789, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1788222, Length=191, Percent_Identity=26.1780104712042, Blast_Score=70, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011990
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 21059; Mature: 21059

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNTALSQLLNLEDNLEVLGSATNGKHALAEIQRLQPNVAILDIEMPMMSGLEVAEVLHD
CCHHHHHHHHCCCCCHHHEECCCCCHHHHHHHHHCCCCEEEEEECCHHHCCHHHHHHHHH
KQLATKVIILTTFAQKTYFEKAVEVEVAGYLLKDSPSDDLIETINKVMMGRTVYDPELVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHCCCCCCHHHEE
TALSSNKNPLSEREMSVLKAAVSGDATKVMAQKLFLSEGTVRNYLSAIFSKLGVHNRLEA
EEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHH
IEVAKKNKWIN
HHHHHHCCCCC
>Mature Secondary Structure
MLNTALSQLLNLEDNLEVLGSATNGKHALAEIQRLQPNVAILDIEMPMMSGLEVAEVLHD
CCHHHHHHHHCCCCCHHHEECCCCCHHHHHHHHHCCCCEEEEEECCHHHCCHHHHHHHHH
KQLATKVIILTTFAQKTYFEKAVEVEVAGYLLKDSPSDDLIETINKVMMGRTVYDPELVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHCCCCCCHHHEE
TALSSNKNPLSEREMSVLKAAVSGDATKVMAQKLFLSEGTVRNYLSAIFSKLGVHNRLEA
EEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHH
IEVAKKNKWIN
HHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]