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The map label for this gene is desK [H]

Identifier: 116493462

GI number: 116493462

Start: 1710795

End: 1711910

Strand: Reverse

Name: desK [H]

Synonym: PEPE_1734

Alternate gene names: 116493462

Gene position: 1711910-1710795 (Counterclockwise)

Preceding gene: 116493463

Following gene: 116493461

Centisome position: 93.43

GC content: 36.11

Gene sequence:

>1116_bases
GTGGTTAAAAATAAATGGAATTTTAGAAATGTGAAATGGGAATATTATATCTGGTTATTATATATGCCATATAATATTTC
GTTTTATTTACCAATTAAATCGGCAACGGATGCTTTTTGGATAGTTATGTGTCTAGGGTTTTTAGCAGATTATATTTGGG
CAGCCGAAAAACCAGAATGGCAAAAAGTTTCCATTCCATTAGAAATCTTAATCACGGGAATTTTTACCATTTTTAATTTT
AATTTCTATATGATGGTTTTTACAGCTTGGCAAGTAGCATTTTTGATTGTGGGGAGACCTAAAAAATATGTTATGGCTTT
TTTGGGGGCGTATTACACTATTTTAATTATCGGGCTAGTAGAAGTTATCGAATTATTTCCTACGCAAATTACTACTAATA
CTAGTGGGGGAATATTTGGAAATATTATGGGTCTGGCGTTTCCAATTATTTCACCAATCATGTCATATGCTTTTGCAGTT
TCGATTCGCTACCGTCGAAAAATGCGTCAAGATAACCGACGCTTAGAAACCATTGTTCGTCGGGGTGAACGGGAACGAAT
TGCTCGGGACTTACATGATACTTTAGGACAAAGCTTTTCGATGATTACGGTTAAAACAGAATTAGCTAAGAAATTGTTAG
AAAAAGGTTCGGATCAAGTGGGACGTGAACTAGAAGATATTGCGACTACAAGTCGAGCAAATTTGCAGCTTGTCCGTCAA
ATCGTTAACGATTTACATCAACAATCATTAAGTGAAGCTTTATTTATCCAGAGTAAGAATCTGACGGATGCTAATATTTT
TATGATGACTGAAGGTGAAAACGAAGCTATAAATTGGCCAACTGAAGTTCAAAATGAATTTGCAGCTGTAATTATTGAAG
CAATCACAAACATTATTCGTCATGCCCAAGCCCGTACAGTTCAGATCCGATTTATGCATGCTGAGGGTCGCTATCGAATT
GAAGTGCAAGATGATGGACATGCGCAAACTTTTATTCGACAGGGTTCTAATGGGATTTCCGGTATGCAAGCAAGGATGCG
CGCTAAACATGGTGAATTTGATATTCAACAAAATAAAATAGGAACGCAAGTTTCCTTTAACTTACCAGAGGAGTAA

Upstream 100 bases:

>100_bases
AACTGGAATGACGTTCAGGGTCTAGGAGTTTGGATAGTTGGATTGGTCGCCGCAATGACAGTAGGAACAATTATCACACG
ACGAAAGGGTAGATTGGCTC

Downstream 100 bases:

>100_bases
CGATGATAACTTTATATCTCGCAGAAGACCAAAGCATGTTAAATACTGCATTAAGTCAGCTATTAAATTTAGAAGATAAT
TTAGAAGTTTTAGGATCGGC

Product: Signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 371; Mature: 371

Protein sequence:

>371_residues
MVKNKWNFRNVKWEYYIWLLYMPYNISFYLPIKSATDAFWIVMCLGFLADYIWAAEKPEWQKVSIPLEILITGIFTIFNF
NFYMMVFTAWQVAFLIVGRPKKYVMAFLGAYYTILIIGLVEVIELFPTQITTNTSGGIFGNIMGLAFPIISPIMSYAFAV
SIRYRRKMRQDNRRLETIVRRGERERIARDLHDTLGQSFSMITVKTELAKKLLEKGSDQVGRELEDIATTSRANLQLVRQ
IVNDLHQQSLSEALFIQSKNLTDANIFMMTEGENEAINWPTEVQNEFAAVIIEAITNIIRHAQARTVQIRFMHAEGRYRI
EVQDDGHAQTFIRQGSNGISGMQARMRAKHGEFDIQQNKIGTQVSFNLPEE

Sequences:

>Translated_371_residues
MVKNKWNFRNVKWEYYIWLLYMPYNISFYLPIKSATDAFWIVMCLGFLADYIWAAEKPEWQKVSIPLEILITGIFTIFNF
NFYMMVFTAWQVAFLIVGRPKKYVMAFLGAYYTILIIGLVEVIELFPTQITTNTSGGIFGNIMGLAFPIISPIMSYAFAV
SIRYRRKMRQDNRRLETIVRRGERERIARDLHDTLGQSFSMITVKTELAKKLLEKGSDQVGRELEDIATTSRANLQLVRQ
IVNDLHQQSLSEALFIQSKNLTDANIFMMTEGENEAINWPTEVQNEFAAVIIEAITNIIRHAQARTVQIRFMHAEGRYRI
EVQDDGHAQTFIRQGSNGISGMQARMRAKHGEFDIQQNKIGTQVSFNLPEE
>Mature_371_residues
MVKNKWNFRNVKWEYYIWLLYMPYNISFYLPIKSATDAFWIVMCLGFLADYIWAAEKPEWQKVSIPLEILITGIFTIFNF
NFYMMVFTAWQVAFLIVGRPKKYVMAFLGAYYTILIIGLVEVIELFPTQITTNTSGGIFGNIMGLAFPIISPIMSYAFAV
SIRYRRKMRQDNRRLETIVRRGERERIARDLHDTLGQSFSMITVKTELAKKLLEKGSDQVGRELEDIATTSRANLQLVRQ
IVNDLHQQSLSEALFIQSKNLTDANIFMMTEGENEAINWPTEVQNEFAAVIIEAITNIIRHAQARTVQIRFMHAEGRYRI
EVQDDGHAQTFIRQGSNGISGMQARMRAKHGEFDIQQNKIGTQVSFNLPEE

Specific function: Member of the two-component regulatory system desR/desK, responsible for cold induction of the des gene coding for the Delta5 acyl-lipid desaturase. Acts as a sensor of the membrane fluidity. Probably activates desR by phosphorylation [H]

COG id: COG4585

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011712 [H]

Pfam domain/function: PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 42930; Mature: 42930

Theoretical pI: Translated: 9.09; Mature: 9.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKNKWNFRNVKWEYYIWLLYMPYNISFYLPIKSATDAFWIVMCLGFLADYIWAAEKPEW
CCCCCCCCCCEEEEEEEEEEEECCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCC
QKVSIPLEILITGIFTIFNFNFYMMVFTAWQVAFLIVGRPKKYVMAFLGAYYTILIIGLV
EEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
EVIELFPTQITTNTSGGIFGNIMGLAFPIISPIMSYAFAVSIRYRRKMRQDNRRLETIVR
HHHHHCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGERERIARDLHDTLGQSFSMITVKTELAKKLLEKGSDQVGRELEDIATTSRANLQLVRQ
CCCHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHH
IVNDLHQQSLSEALFIQSKNLTDANIFMMTEGENEAINWPTEVQNEFAAVIIEAITNIIR
HHHHHHHHHHHHHHHEECCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
HAQARTVQIRFMHAEGRYRIEVQDDGHAQTFIRQGSNGISGMQARMRAKHGEFDIQQNKI
HCCCEEEEEEEEECCCEEEEEECCCCCHHHHHHCCCCCCHHHHHHHHHCCCCCCEECCCC
GTQVSFNLPEE
CCEEEECCCCC
>Mature Secondary Structure
MVKNKWNFRNVKWEYYIWLLYMPYNISFYLPIKSATDAFWIVMCLGFLADYIWAAEKPEW
CCCCCCCCCCEEEEEEEEEEEECCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCC
QKVSIPLEILITGIFTIFNFNFYMMVFTAWQVAFLIVGRPKKYVMAFLGAYYTILIIGLV
EEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
EVIELFPTQITTNTSGGIFGNIMGLAFPIISPIMSYAFAVSIRYRRKMRQDNRRLETIVR
HHHHHCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGERERIARDLHDTLGQSFSMITVKTELAKKLLEKGSDQVGRELEDIATTSRANLQLVRQ
CCCHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHH
IVNDLHQQSLSEALFIQSKNLTDANIFMMTEGENEAINWPTEVQNEFAAVIIEAITNIIR
HHHHHHHHHHHHHHHEECCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
HAQARTVQIRFMHAEGRYRIEVQDDGHAQTFIRQGSNGISGMQARMRAKHGEFDIQQNKI
HCCCEEEEEEEEECCCEEEEEECCCCCHHHHHHCCCCCCHHHHHHHHHCCCCCCEECCCC
GTQVSFNLPEE
CCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]