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The map label for this gene is obg

Identifier: 116492895

GI number: 116492895

Start: 1132997

End: 1134289

Strand: Reverse

Name: obg

Synonym: PEPE_1134

Alternate gene names: 116492895

Gene position: 1134289-1132997 (Counterclockwise)

Preceding gene: 116492896

Following gene: 116492893

Centisome position: 61.9

GC content: 39.06

Gene sequence:

>1293_bases
ATGTTTGTAGATCAAGTTAAAATTAATGTTAAAGCTGGTAACGGTGGGAATGGGATTGTAGCTTTCCGTCGTGAAAAATA
TGTTCCCAACGGTGGACCAGCTGGTGGCGATGGAGGCCGTGGTGGTAACGTCGTCTTAAAAGTTGACCCAGGTCTTAGAA
CTTTGATGGATTTCAGGTATCGTCATAAGTTCAAGGCGGATTCTGGGAAAAATGGGATGAATAAACAAATGACGGGACGT
AGTTCTCAAGATCTCGTAATTTCCGTACCAGGTGGAACAATTGTCCGCGATTTAACCACAGGACGTGTAATTGGTGATTT
AACCGATAACGGACAAGAATTAGTGGTGGCTAAAGGTGGTCGTGGAGGCCGTGGAAATATGCGTTTTGCTAGCCCTCGAA
ATCCTGCTCCCGAAATTTCTGAAAATGGGGAACCTGGAGAAGAAATTGAATTACAATTAGAACTTAAGGTTTTAGCGGAT
GTTGGATTATTAGGATTTCCATCTGTCGGTAAATCAACACTACTTTCAGTAGTAACGAGTGCGAAGCCTAAAATTGCGGA
ATATCATTTTACGACCTTAGTACCTAACTTAGGGATGGTTCAATTGGATGATGGTCGTGATTTTGTTATTGCTGACATTC
CTGGTTTGATTGAAGGAGCTTCTCAAGGTGTGGGATTAGGTTTTGAATTCCTACGTCACGTTGAACGAACACGGGTCTTA
CTTCATTTAGTAGATATGAGTGGGATGACGGAAGAAGATCCATTCACTAATTTCCGTCAAATCAATGAAGAGCTAAAAAA
ATATAATCCTGAATTGTTGGAACGTCGGCAAATTATTGTTCCGACTAAAATGGATTTACCTGGATCCGATGAAGAGCTTA
AGAAATTTGAAAAACAAGTTCGAGCTGATGAACGTTATGCTGATTTTGAAATTTTTCCAATTTCTTCTATCACCCATAAT
GGACTTGAAAAACTAGTTGCTCGAACTGCAGATGTATTGGAAGAAATTCCACAGCATTCATTAATTGCTACTTCTGACGA
AGAAACTGAAAAGACATATGAATTTAGTTCAGAAAAAGACTTTACCATTGAAAATATTGATGACGTTTGGGTTATTGAGG
GTGAAAAGATTGAAAAACTCTTTAAGATGACTGATACAACGCATGATGAAAGTCTTTTACGCTTTGCTCGTCAAATGCGT
GGCATGGGAATTGATGATGAATTACGTCGCTTAGGTGCACGTAATGGAGATAGTGTTCAAATTTTGGACTTTGTATTTGA
ATTTGTAGAATAA

Upstream 100 bases:

>100_bases
GCTAAAACTATCAAAGTGTCCTTATCAGTGCACGGAAAATAGGGTACACTAACAAATGGATAGGAATTTCTCGGTGAAAT
AAAATATTTAGGAGAAAATA

Downstream 100 bases:

>100_bases
AAATTATTAAAGTCAGTGGTAAGTACAGAAAGGAATGTTTAATCTTAAACAATTCTGTTCTCATCACTGACTTTTTACTT
GATTACTAGATATTGATCAC

Product: GTPase

Products: NA

Alternate protein names: GTP-binding protein obg

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MFVDQVKINVKAGNGGNGIVAFRREKYVPNGGPAGGDGGRGGNVVLKVDPGLRTLMDFRYRHKFKADSGKNGMNKQMTGR
SSQDLVISVPGGTIVRDLTTGRVIGDLTDNGQELVVAKGGRGGRGNMRFASPRNPAPEISENGEPGEEIELQLELKVLAD
VGLLGFPSVGKSTLLSVVTSAKPKIAEYHFTTLVPNLGMVQLDDGRDFVIADIPGLIEGASQGVGLGFEFLRHVERTRVL
LHLVDMSGMTEEDPFTNFRQINEELKKYNPELLERRQIIVPTKMDLPGSDEELKKFEKQVRADERYADFEIFPISSITHN
GLEKLVARTADVLEEIPQHSLIATSDEETEKTYEFSSEKDFTIENIDDVWVIEGEKIEKLFKMTDTTHDESLLRFARQMR
GMGIDDELRRLGARNGDSVQILDFVFEFVE

Sequences:

>Translated_430_residues
MFVDQVKINVKAGNGGNGIVAFRREKYVPNGGPAGGDGGRGGNVVLKVDPGLRTLMDFRYRHKFKADSGKNGMNKQMTGR
SSQDLVISVPGGTIVRDLTTGRVIGDLTDNGQELVVAKGGRGGRGNMRFASPRNPAPEISENGEPGEEIELQLELKVLAD
VGLLGFPSVGKSTLLSVVTSAKPKIAEYHFTTLVPNLGMVQLDDGRDFVIADIPGLIEGASQGVGLGFEFLRHVERTRVL
LHLVDMSGMTEEDPFTNFRQINEELKKYNPELLERRQIIVPTKMDLPGSDEELKKFEKQVRADERYADFEIFPISSITHN
GLEKLVARTADVLEEIPQHSLIATSDEETEKTYEFSSEKDFTIENIDDVWVIEGEKIEKLFKMTDTTHDESLLRFARQMR
GMGIDDELRRLGARNGDSVQILDFVFEFVE
>Mature_430_residues
MFVDQVKINVKAGNGGNGIVAFRREKYVPNGGPAGGDGGRGGNVVLKVDPGLRTLMDFRYRHKFKADSGKNGMNKQMTGR
SSQDLVISVPGGTIVRDLTTGRVIGDLTDNGQELVVAKGGRGGRGNMRFASPRNPAPEISENGEPGEEIELQLELKVLAD
VGLLGFPSVGKSTLLSVVTSAKPKIAEYHFTTLVPNLGMVQLDDGRDFVIADIPGLIEGASQGVGLGFEFLRHVERTRVL
LHLVDMSGMTEEDPFTNFRQINEELKKYNPELLERRQIIVPTKMDLPGSDEELKKFEKQVRADERYADFEIFPISSITHN
GLEKLVARTADVLEEIPQHSLIATSDEETEKTYEFSSEKDFTIENIDDVWVIEGEKIEKLFKMTDTTHDESLLRFARQMR
GMGIDDELRRLGARNGDSVQILDFVFEFVE

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain

Homologues:

Organism=Homo sapiens, GI24308117, Length=325, Percent_Identity=40.6153846153846, Blast_Score=190, Evalue=2e-48,
Organism=Homo sapiens, GI111955139, Length=295, Percent_Identity=36.6101694915254, Blast_Score=172, Evalue=4e-43,
Organism=Homo sapiens, GI111955063, Length=181, Percent_Identity=39.2265193370166, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI4557537, Length=89, Percent_Identity=41.5730337078652, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1789574, Length=371, Percent_Identity=44.4743935309973, Blast_Score=275, Evalue=4e-75,
Organism=Escherichia coli, GI1787454, Length=142, Percent_Identity=33.0985915492958, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17508313, Length=326, Percent_Identity=37.7300613496933, Blast_Score=164, Evalue=7e-41,
Organism=Caenorhabditis elegans, GI17552324, Length=374, Percent_Identity=27.2727272727273, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI71981008, Length=226, Percent_Identity=27.8761061946903, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17509631, Length=128, Percent_Identity=35.15625, Blast_Score=70, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6321962, Length=194, Percent_Identity=37.1134020618557, Blast_Score=125, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6321612, Length=89, Percent_Identity=41.5730337078652, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319281, Length=87, Percent_Identity=45.9770114942529, Blast_Score=67, Evalue=4e-12,
Organism=Drosophila melanogaster, GI20129375, Length=303, Percent_Identity=38.9438943894389, Blast_Score=180, Evalue=1e-45,
Organism=Drosophila melanogaster, GI24585318, Length=370, Percent_Identity=32.1621621621622, Blast_Score=168, Evalue=6e-42,
Organism=Drosophila melanogaster, GI21356473, Length=121, Percent_Identity=37.1900826446281, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24640873, Length=129, Percent_Identity=31.7829457364341, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24640877, Length=129, Percent_Identity=31.7829457364341, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24640875, Length=129, Percent_Identity=31.7829457364341, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OBG_PEDPA (Q03F34)

Other databases:

- EMBL:   CP000422
- RefSeq:   YP_804630.1
- ProteinModelPortal:   Q03F34
- SMR:   Q03F34
- STRING:   Q03F34
- GeneID:   4417103
- GenomeReviews:   CP000422_GR
- KEGG:   ppe:PEPE_1134
- NMPDR:   fig|278197.10.peg.995
- eggNOG:   COG0536
- HOGENOM:   HBG716038
- OMA:   HFTTLVP
- PhylomeDB:   Q03F34
- BioCyc:   PPEN278197:PEPE_1134-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01454
- InterPro:   IPR014100
- InterPro:   IPR015349
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- Gene3D:   G3DSA:2.70.210.12
- PANTHER:   PTHR11702:SF3
- PIRSF:   PIRSF002401
- PRINTS:   PR00326
- TIGRFAMs:   TIGR02729
- TIGRFAMs:   TIGR03595

Pfam domain/function: PF09269 DUF1967; PF01018 GTP1_OBG; PF01926 MMR_HSR1; SSF102741 GTP-bd_prot_GTP1/OBG_C; SSF82051 GTP1_OBG_sub

EC number: NA

Molecular weight: Translated: 47731; Mature: 47731

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFVDQVKINVKAGNGGNGIVAFRREKYVPNGGPAGGDGGRGGNVVLKVDPGLRTLMDFRY
CCCCEEEEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHH
RHKFKADSGKNGMNKQMTGRSSQDLVISVPGGTIVRDLTTGRVIGDLTDNGQELVVAKGG
HHCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCEEEECCCCCEEEECCCCCCEEEEEECC
RGGRGNMRFASPRNPAPEISENGEPGEEIELQLELKVLADVGLLGFPSVGKSTLLSVVTS
CCCCCCEEECCCCCCCCCCCCCCCCCCEEEEEEEEEEEECCCCCCCCCCCHHHHHHHHHC
AKPKIAEYHFTTLVPNLGMVQLDDGRDFVIADIPGLIEGASQGVGLGFEFLRHVERTRVL
CCCCHHHEEHHHHCCCCCEEEECCCCEEEEECCCHHHHCCCCCCCHHHHHHHHHHHHHHH
LHLVDMSGMTEEDPFTNFRQINEELKKYNPELLERRQIIVPTKMDLPGSDEELKKFEKQV
HHHHCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHCCEEEECCCCCCCCCHHHHHHHHHHH
RADERYADFEIFPISSITHNGLEKLVARTADVLEEIPQHSLIATSDEETEKTYEFSSEKD
HCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHCCCCCCC
FTIENIDDVWVIEGEKIEKLFKMTDTTHDESLLRFARQMRGMGIDDELRRLGARNGDSVQ
CEEECCCCEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCH
ILDFVFEFVE
HHHHHHHHHC
>Mature Secondary Structure
MFVDQVKINVKAGNGGNGIVAFRREKYVPNGGPAGGDGGRGGNVVLKVDPGLRTLMDFRY
CCCCEEEEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHH
RHKFKADSGKNGMNKQMTGRSSQDLVISVPGGTIVRDLTTGRVIGDLTDNGQELVVAKGG
HHCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCEEEECCCCCEEEECCCCCCEEEEEECC
RGGRGNMRFASPRNPAPEISENGEPGEEIELQLELKVLADVGLLGFPSVGKSTLLSVVTS
CCCCCCEEECCCCCCCCCCCCCCCCCCEEEEEEEEEEEECCCCCCCCCCCHHHHHHHHHC
AKPKIAEYHFTTLVPNLGMVQLDDGRDFVIADIPGLIEGASQGVGLGFEFLRHVERTRVL
CCCCHHHEEHHHHCCCCCEEEECCCCEEEEECCCHHHHCCCCCCCHHHHHHHHHHHHHHH
LHLVDMSGMTEEDPFTNFRQINEELKKYNPELLERRQIIVPTKMDLPGSDEELKKFEKQV
HHHHCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHCCEEEECCCCCCCCCHHHHHHHHHHH
RADERYADFEIFPISSITHNGLEKLVARTADVLEEIPQHSLIATSDEETEKTYEFSSEKD
HCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHCCCCCCC
FTIENIDDVWVIEGEKIEKLFKMTDTTHDESLLRFARQMRGMGIDDELRRLGARNGDSVQ
CEEECCCCEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCH
ILDFVFEFVE
HHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA