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The map label for this gene is dtd

Identifier: 116492881

GI number: 116492881

Start: 1118402

End: 1118851

Strand: Reverse

Name: dtd

Synonym: PEPE_1119

Alternate gene names: 116492881

Gene position: 1118851-1118402 (Counterclockwise)

Preceding gene: 116492882

Following gene: 116492880

Centisome position: 61.06

GC content: 39.33

Gene sequence:

>450_bases
ATGAGAGTTGTAATTCAGAGAGTATCAAAAGCAAGCGTTACAATTGAAGAGAATGTAGTTGGAAAGGTCGGGCCGGGATT
CATGCTATTAGTGGCTTTCAACGATGAAGATACGGACGCTGATCTCGACTTTGCAGTACGCAAAATTGTTAATATGCGTA
TTTTTGAAGACGAGCAAGCTAAGATGAATCTGTCTATTAACGATGTAAAAGGAGCGATTCTTTCTGTTTCTCAATTTACC
TTATTTGCTTCCACTAAAAAAGGAAATCGGCCGAGCTTTACTAAATCGGGTAACCCAGAGTTGGCTAGTAAACTGTATGA
TCAGTTCAATGCTAAGTTACGTGCTACAGGAATTGAAGTACAAACTGGTCAATTTGGGGCGGATATGCAGGTGGAATTGG
TTAACGATGGACCGGTTACGATTGTTTTAGATACACAAAATAAAGAATGA

Upstream 100 bases:

>100_bases
CGGAGTGCGAAATTTATTACATTTACAACGAGTTATGGAAAGCTTAAAAAATGTTAAGGACGTTTATGTGGTTAAACGTC
CAACCCATTAGGAGTAATGT

Downstream 100 bases:

>100_bases
TTGAAAGAGCTTAAATTAGAAGTCTTAGACTATTGTTGGCGTAGAGCAAACATAGTTTAGCTCCTAAGATAAGCTCTTTT
TTAAGGAGAAAATTATGGAT

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 149; Mature: 149

Protein sequence:

>149_residues
MRVVIQRVSKASVTIEENVVGKVGPGFMLLVAFNDEDTDADLDFAVRKIVNMRIFEDEQAKMNLSINDVKGAILSVSQFT
LFASTKKGNRPSFTKSGNPELASKLYDQFNAKLRATGIEVQTGQFGADMQVELVNDGPVTIVLDTQNKE

Sequences:

>Translated_149_residues
MRVVIQRVSKASVTIEENVVGKVGPGFMLLVAFNDEDTDADLDFAVRKIVNMRIFEDEQAKMNLSINDVKGAILSVSQFT
LFASTKKGNRPSFTKSGNPELASKLYDQFNAKLRATGIEVQTGQFGADMQVELVNDGPVTIVLDTQNKE
>Mature_149_residues
MRVVIQRVSKASVTIEENVVGKVGPGFMLLVAFNDEDTDADLDFAVRKIVNMRIFEDEQAKMNLSINDVKGAILSVSQFT
LFASTKKGNRPSFTKSGNPELASKLYDQFNAKLRATGIEVQTGQFGADMQVELVNDGPVTIVLDTQNKE

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family

Homologues:

Organism=Homo sapiens, GI30795227, Length=148, Percent_Identity=43.2432432432432, Blast_Score=113, Evalue=7e-26,
Organism=Escherichia coli, GI1790320, Length=143, Percent_Identity=45.4545454545455, Blast_Score=138, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI115533292, Length=151, Percent_Identity=41.0596026490066, Blast_Score=119, Evalue=7e-28,
Organism=Saccharomyces cerevisiae, GI6319982, Length=148, Percent_Identity=43.9189189189189, Blast_Score=125, Evalue=2e-30,
Organism=Drosophila melanogaster, GI281361569, Length=147, Percent_Identity=42.8571428571429, Blast_Score=122, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DTD_PEDPA (Q03F48)

Other databases:

- EMBL:   CP000422
- RefSeq:   YP_804616.1
- ProteinModelPortal:   Q03F48
- SMR:   Q03F48
- STRING:   Q03F48
- GeneID:   4417088
- GenomeReviews:   CP000422_GR
- KEGG:   ppe:PEPE_1119
- NMPDR:   fig|278197.10.peg.983
- eggNOG:   COG1490
- HOGENOM:   HBG286048
- OMA:   MKAVIQR
- PhylomeDB:   Q03F48
- ProtClustDB:   PRK05273
- BioCyc:   PPEN278197:PEPE_1119-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00518
- InterPro:   IPR003732
- Gene3D:   G3DSA:3.50.80.10
- PANTHER:   PTHR10472
- TIGRFAMs:   TIGR00256

Pfam domain/function: PF02580 Tyr_Deacylase; SSF69500 DTyrtRNA_deacyls

EC number: NA

Molecular weight: Translated: 16373; Mature: 16373

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: ACT_SITE 80-80

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVVIQRVSKASVTIEENVVGKVGPGFMLLVAFNDEDTDADLDFAVRKIVNMRIFEDEQA
CCCEEEECCCCEEEEECCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHEEEEECCCC
KMNLSINDVKGAILSVSQFTLFASTKKGNRPSFTKSGNPELASKLYDQFNAKLRATGIEV
EEEEEECCCCCEEEEEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCEEEEECEEE
QTGQFGADMQVELVNDGPVTIVLDTQNKE
ECCCCCCCEEEEEECCCCEEEEEECCCCC
>Mature Secondary Structure
MRVVIQRVSKASVTIEENVVGKVGPGFMLLVAFNDEDTDADLDFAVRKIVNMRIFEDEQA
CCCEEEECCCCEEEEECCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHEEEEECCCC
KMNLSINDVKGAILSVSQFTLFASTKKGNRPSFTKSGNPELASKLYDQFNAKLRATGIEV
EEEEEECCCCCEEEEEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCEEEEECEEE
QTGQFGADMQVELVNDGPVTIVLDTQNKE
ECCCCCCCEEEEEECCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA