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The map label for this gene is clpL [H]

Identifier: 116492739

GI number: 116492739

Start: 983632

End: 985746

Strand: Reverse

Name: clpL [H]

Synonym: PEPE_0976

Alternate gene names: 116492739

Gene position: 985746-983632 (Counterclockwise)

Preceding gene: 116492740

Following gene: 116492738

Centisome position: 53.8

GC content: 38.11

Gene sequence:

>2115_bases
ATGGCCAATTTTTACGGAAATGATCCTTTTTTCAACAATGATATGGATGATATTTTTAATCAAGTATTTAAACGTATGGG
GAATCCTAACTCAGATTCTGCTCGCTACTTGGTTAATGGTCAATCGTTAACTCCAGACGAGTTTGCTCAATATCGAGCAA
CTGGTAAATTACCAGAACAAGCAAAAACAATTGAAGTATCTAAAGATGGACAACAAGCTCTTAAAAAGGGTGGTATTTTA
GAAAAACTAGGCACCAACTTAACAGAACAAGCACGCGATGGATTACTAGATTCAGTTATTGGACGTGAAAATGAAATTCA
AGAAACAGCGGAAATTTTAAGCCGTCGAACCAAAAATAATCCAATTTTAGTTGGGGATGCAGGTGTTGGTAAAACAGCCA
TCGTTGAAGGATTGGCACAAGCAATTGTAAATGGTAAAGTTCCAGAAGCAATTCGGGACAAAGAAATTTACTCTATTGAC
TTGTCCTCCTTAGAAGCTGGAACTCAATATCGCGGTTCTTTTGAAGAGAATATCAAAGACTTAGTCAAGGAAGTTAAGGC
TGCTGGCAATATTATTCTATTCTTTGATGAAATTCACCAGATAATTGGTACTGGTTCAACAGGTGGTGAAGACGGTGGTA
AAGGCTTAGCTGATATTATCAAGCCAGCATTGTCTCGTGGTGAACTAACCGTTATTGGCGCCACTACCCAAGATGAATAT
CGAAATACAATTTTGAAAAACGCAGCTTTGGCTCGTCGATTCAATGATGTTGTAGTCAATGAACCTAATGCTGAAGACAC
GCTTGAAATTCTAAAGGGTATCAAAAACTTGTATGAGGAACATCACCATGTAAAATTGCCAGATGATGTTTTGAAGGCAA
CGGTAGATTACTCCATCCAATATATTCCACAAAGAACGCTACCAGATAAAGCAATTGATTTGATTGATATGACAGCGGCT
CATTTGGCAGCACATCAGCCTGAAAATGATGAAACAGCTTTAAAGGAAAAGCTCAATCAATTGCAAAAAGAAAAAGATCA
AGCGGTGGAAAAAGAAGACTTTAAGCGGGCTGCGGATTTGAAGCAACAAATCGAGGCTACTAATAAGCAAATTGATAATG
TAGGTAAGAAGGAAGAAGTAGTGGCTACCGTCGATGATGTTGCTCAATCAGTAGAACGATTAACGGGAATTCCAGTCTCA
GATATGGGTGCTAATGATATTGAACGGTTAAAAGATTTGGATAGTCGCTTAAAGAGTAAAGTTATCGGTCAAGATGAAGC
GGTAGCAATGGTTGCTAGAGCTATTCGTCGGAATCGAGCTGGCTTCTCAGAAGGTGAACAGCCTATCGGTAGTTTCCTAT
TTGTTGGTCCAACCGGGGTTGGTAAAACTGAACTAGCTAAACAATTAGCATTAGACATGTTTGGTGATAAGGATGCAATC
ATTCGATTGGATATGAGTGAGTATTCAGATCGGACCGCTGTTTCAAAATTAATTGGTACATCAGCTGGTTATGTAGGCTA
TGATGATAACTCTAATACCTTAACGGAACGAGTACGTCGAAATCCTTATTCAATCGTATTACTAGATGAAATTGAAAAAG
CCGATCCGCAAGTATTGACGCTTTTGCTTCAGGTAATGGATGACGGTCGTTTGACGGATGGTCAAGGTAATGTAATTAAC
TTCAAGAATACCATTATTATTGCTACATCCAATGCTGGATTTGGTAATGAAAAGTTAACTGGCGATGCAGACAAAGATCA
AACTTTAATGGATAAGTTGGCTCCATTCTTCCGTCCAGAATTCCTAAACCGGTTCAATGGAATCGTTGAATTCTCACATC
TAACTAAGAAAGATTTAAGTCAGATTGTTGATTTAATGATTTCTGATGTTCAAAAAACACTAGCGAAAAAAGATTTGACT
TTGAAAGTAACCGATGCAGCTAAGGATTGGTTGATGGAACAAGGATATGACGAAGCAATGGGAGCTCGTCCATTAAGAAG
GGTGATTGAACAACAAATTCGTGATAAGGTAACAGATTTCTATTTAGATCATTTGGATATTAAGCATTTAAAAGCTGACT
TGAAGGATGATCAAATCGTGATTGAGCAAGCCTAA

Upstream 100 bases:

>100_bases
GCTAAAAAGGAGTTATAATACAGTTGTAAGTAAAAAAGAGTGTTTTTACTTAGTTTTAAGACACAATTTTACTTTATTTA
ATTAACGGAGGTGTTGTTAT

Downstream 100 bases:

>100_bases
CTTAGCAGGTAGTTTACTTTGGACTTTATTTACGAAAAGCGAGGATGACAGATTAATTTCTGTCATCCTCGCTTTTTATT
TTGGTTTTAGGCCATAGTTA

Product: ATP-binding subunit of Clp protease and DnaK/DnaJ chaperones

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 704; Mature: 703

Protein sequence:

>704_residues
MANFYGNDPFFNNDMDDIFNQVFKRMGNPNSDSARYLVNGQSLTPDEFAQYRATGKLPEQAKTIEVSKDGQQALKKGGIL
EKLGTNLTEQARDGLLDSVIGRENEIQETAEILSRRTKNNPILVGDAGVGKTAIVEGLAQAIVNGKVPEAIRDKEIYSID
LSSLEAGTQYRGSFEENIKDLVKEVKAAGNIILFFDEIHQIIGTGSTGGEDGGKGLADIIKPALSRGELTVIGATTQDEY
RNTILKNAALARRFNDVVVNEPNAEDTLEILKGIKNLYEEHHHVKLPDDVLKATVDYSIQYIPQRTLPDKAIDLIDMTAA
HLAAHQPENDETALKEKLNQLQKEKDQAVEKEDFKRAADLKQQIEATNKQIDNVGKKEEVVATVDDVAQSVERLTGIPVS
DMGANDIERLKDLDSRLKSKVIGQDEAVAMVARAIRRNRAGFSEGEQPIGSFLFVGPTGVGKTELAKQLALDMFGDKDAI
IRLDMSEYSDRTAVSKLIGTSAGYVGYDDNSNTLTERVRRNPYSIVLLDEIEKADPQVLTLLLQVMDDGRLTDGQGNVIN
FKNTIIIATSNAGFGNEKLTGDADKDQTLMDKLAPFFRPEFLNRFNGIVEFSHLTKKDLSQIVDLMISDVQKTLAKKDLT
LKVTDAAKDWLMEQGYDEAMGARPLRRVIEQQIRDKVTDFYLDHLDIKHLKADLKDDQIVIEQA

Sequences:

>Translated_704_residues
MANFYGNDPFFNNDMDDIFNQVFKRMGNPNSDSARYLVNGQSLTPDEFAQYRATGKLPEQAKTIEVSKDGQQALKKGGIL
EKLGTNLTEQARDGLLDSVIGRENEIQETAEILSRRTKNNPILVGDAGVGKTAIVEGLAQAIVNGKVPEAIRDKEIYSID
LSSLEAGTQYRGSFEENIKDLVKEVKAAGNIILFFDEIHQIIGTGSTGGEDGGKGLADIIKPALSRGELTVIGATTQDEY
RNTILKNAALARRFNDVVVNEPNAEDTLEILKGIKNLYEEHHHVKLPDDVLKATVDYSIQYIPQRTLPDKAIDLIDMTAA
HLAAHQPENDETALKEKLNQLQKEKDQAVEKEDFKRAADLKQQIEATNKQIDNVGKKEEVVATVDDVAQSVERLTGIPVS
DMGANDIERLKDLDSRLKSKVIGQDEAVAMVARAIRRNRAGFSEGEQPIGSFLFVGPTGVGKTELAKQLALDMFGDKDAI
IRLDMSEYSDRTAVSKLIGTSAGYVGYDDNSNTLTERVRRNPYSIVLLDEIEKADPQVLTLLLQVMDDGRLTDGQGNVIN
FKNTIIIATSNAGFGNEKLTGDADKDQTLMDKLAPFFRPEFLNRFNGIVEFSHLTKKDLSQIVDLMISDVQKTLAKKDLT
LKVTDAAKDWLMEQGYDEAMGARPLRRVIEQQIRDKVTDFYLDHLDIKHLKADLKDDQIVIEQA
>Mature_703_residues
ANFYGNDPFFNNDMDDIFNQVFKRMGNPNSDSARYLVNGQSLTPDEFAQYRATGKLPEQAKTIEVSKDGQQALKKGGILE
KLGTNLTEQARDGLLDSVIGRENEIQETAEILSRRTKNNPILVGDAGVGKTAIVEGLAQAIVNGKVPEAIRDKEIYSIDL
SSLEAGTQYRGSFEENIKDLVKEVKAAGNIILFFDEIHQIIGTGSTGGEDGGKGLADIIKPALSRGELTVIGATTQDEYR
NTILKNAALARRFNDVVVNEPNAEDTLEILKGIKNLYEEHHHVKLPDDVLKATVDYSIQYIPQRTLPDKAIDLIDMTAAH
LAAHQPENDETALKEKLNQLQKEKDQAVEKEDFKRAADLKQQIEATNKQIDNVGKKEEVVATVDDVAQSVERLTGIPVSD
MGANDIERLKDLDSRLKSKVIGQDEAVAMVARAIRRNRAGFSEGEQPIGSFLFVGPTGVGKTELAKQLALDMFGDKDAII
RLDMSEYSDRTAVSKLIGTSAGYVGYDDNSNTLTERVRRNPYSIVLLDEIEKADPQVLTLLLQVMDDGRLTDGQGNVINF
KNTIIIATSNAGFGNEKLTGDADKDQTLMDKLAPFFRPEFLNRFNGIVEFSHLTKKDLSQIVDLMISDVQKTLAKKDLTL
KVTDAAKDWLMEQGYDEAMGARPLRRVIEQQIRDKVTDFYLDHLDIKHLKADLKDDQIVIEQA

Specific function: Could be the ATP-dependent specificity component of an ATP-dependent protease [H]

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=303, Percent_Identity=36.6336633663366, Blast_Score=173, Evalue=4e-43,
Organism=Escherichia coli, GI1788943, Length=717, Percent_Identity=41.1436541143654, Blast_Score=513, Evalue=1e-146,
Organism=Escherichia coli, GI1787109, Length=607, Percent_Identity=41.8451400329489, Blast_Score=456, Evalue=1e-129,
Organism=Saccharomyces cerevisiae, GI6320464, Length=707, Percent_Identity=40.8769448373409, Blast_Score=494, Evalue=1e-140,
Organism=Saccharomyces cerevisiae, GI6323002, Length=390, Percent_Identity=40, Blast_Score=262, Evalue=1e-70,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR001270
- InterPro:   IPR019489 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF10431 ClpB_D2-small [H]

EC number: NA

Molecular weight: Translated: 78010; Mature: 77879

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: PS50151 UVR ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANFYGNDPFFNNDMDDIFNQVFKRMGNPNSDSARYLVNGQSLTPDEFAQYRATGKLPEQ
CCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHCCCCCCC
AKTIEVSKDGQQALKKGGILEKLGTNLTEQARDGLLDSVIGRENEIQETAEILSRRTKNN
CCEEEECCCHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCC
PILVGDAGVGKTAIVEGLAQAIVNGKVPEAIRDKEIYSIDLSSLEAGTQYRGSFEENIKD
CEEEECCCCCHHHHHHHHHHHHHCCCCCHHHCCCCEEEEEHHHHHCCCHHCCCHHHHHHH
LVKEVKAAGNIILFFDEIHQIIGTGSTGGEDGGKGLADIIKPALSRGELTVIGATTQDEY
HHHHHHHCCCEEEEHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCHHHH
RNTILKNAALARRFNDVVVNEPNAEDTLEILKGIKNLYEEHHHVKLPDDVLKATVDYSIQ
HHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHE
YIPQRTLPDKAIDLIDMTAAHLAAHQPENDETALKEKLNQLQKEKDQAVEKEDFKRAADL
ECCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KQQIEATNKQIDNVGKKEEVVATVDDVAQSVERLTGIPVSDMGANDIERLKDLDSRLKSK
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
VIGQDEAVAMVARAIRRNRAGFSEGEQPIGSFLFVGPTGVGKTELAKQLALDMFGDKDAI
HCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCE
IRLDMSEYSDRTAVSKLIGTSAGYVGYDDNSNTLTERVRRNPYSIVLLDEIEKADPQVLT
EEEEHHHCCHHHHHHHHHCCCCCCEEECCCCHHHHHHHHCCCCEEEEECCCCCCCHHHHH
LLLQVMDDGRLTDGQGNVINFKNTIIIATSNAGFGNEKLTGDADKDQTLMDKLAPFFRPE
HHHHHHCCCCEECCCCCEEEECCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCHH
FLNRFNGIVEFSHLTKKDLSQIVDLMISDVQKTLAKKDLTLKVTDAAKDWLMEQGYDEAM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHCCCHHHH
GARPLRRVIEQQIRDKVTDFYLDHLDIKHLKADLKDDQIVIEQA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECC
>Mature Secondary Structure 
ANFYGNDPFFNNDMDDIFNQVFKRMGNPNSDSARYLVNGQSLTPDEFAQYRATGKLPEQ
CCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHCCCCCCC
AKTIEVSKDGQQALKKGGILEKLGTNLTEQARDGLLDSVIGRENEIQETAEILSRRTKNN
CCEEEECCCHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCC
PILVGDAGVGKTAIVEGLAQAIVNGKVPEAIRDKEIYSIDLSSLEAGTQYRGSFEENIKD
CEEEECCCCCHHHHHHHHHHHHHCCCCCHHHCCCCEEEEEHHHHHCCCHHCCCHHHHHHH
LVKEVKAAGNIILFFDEIHQIIGTGSTGGEDGGKGLADIIKPALSRGELTVIGATTQDEY
HHHHHHHCCCEEEEHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCHHHH
RNTILKNAALARRFNDVVVNEPNAEDTLEILKGIKNLYEEHHHVKLPDDVLKATVDYSIQ
HHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHE
YIPQRTLPDKAIDLIDMTAAHLAAHQPENDETALKEKLNQLQKEKDQAVEKEDFKRAADL
ECCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KQQIEATNKQIDNVGKKEEVVATVDDVAQSVERLTGIPVSDMGANDIERLKDLDSRLKSK
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
VIGQDEAVAMVARAIRRNRAGFSEGEQPIGSFLFVGPTGVGKTELAKQLALDMFGDKDAI
HCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCE
IRLDMSEYSDRTAVSKLIGTSAGYVGYDDNSNTLTERVRRNPYSIVLLDEIEKADPQVLT
EEEEHHHCCHHHHHHHHHCCCCCCEEECCCCHHHHHHHHCCCCEEEEECCCCCCCHHHHH
LLLQVMDDGRLTDGQGNVINFKNTIIIATSNAGFGNEKLTGDADKDQTLMDKLAPFFRPE
HHHHHHCCCCEECCCCCEEEECCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCHH
FLNRFNGIVEFSHLTKKDLSQIVDLMISDVQKTLAKKDLTLKVTDAAKDWLMEQGYDEAM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHCCCHHHH
GARPLRRVIEQQIRDKVTDFYLDHLDIKHLKADLKDDQIVIEQA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8387149 [H]