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The map label for this gene is xerC

Identifier: 116492727

GI number: 116492727

Start: 966887

End: 967792

Strand: Reverse

Name: xerC

Synonym: PEPE_0964

Alternate gene names: 116492727

Gene position: 967792-966887 (Counterclockwise)

Preceding gene: 116492728

Following gene: 116492726

Centisome position: 52.82

GC content: 37.97

Gene sequence:

>906_bases
ATGGAATTAATTTCACTGTTCAAACAGTATCTTACGGTTGAACGTCAATATTCAGAGAAAACGGTTACTGCGTACTTAGA
AGATATTGACGCATTCCAAAAATTTTTAACTGATACGGGTGATAAAACGGACCTACTTTTAGTGGATCGTTTCGATGTGA
ATGTTTATATGAGTTATTTATTCGATCGACATTTAGCTCGAACTTCGATTTCGCGAAAAGTATCTGCTTTGCGCTCTTTT
TATCGTTTTTTAGTTAAGAATGATTTAGTGGATAAGAATCCGTTTGAATTAGTCCAACTGAAGAAACAATCTGACAAGCT
GCCACATTTCTTTTATGAAAAGGAAATGAACATGCTCTTTGAAGCGGTTTACCAAGCGGAAGGTGCGCAAAAGCTACGCA
ATATTGCGATTTTAGAAGTGCTTTATGGTACGGGGATGCGAGTAAGTGAATGTGCAGCGTTACAATGGTCAGATATTGAC
TTTTCAATGCAAACTATCCTAGTTCTAGGAAAGGGAAATAAAGAACGTTATGTTCCCTTCGGGCGGTATGCCAAAGAAGC
GCTCCAAAATTACCGAAAAAATGAATGGGAGCCTTTTTTGAGTAAATATAAACAAACCCATAATTTTGTTTTTATTAACC
ATTATGCTAAGCCAATTACCACAACCGGGATTGAATACATTTTGAACCAAGTCATTACCGCCAGCAGCTTAAATGGGAAA
ATTCATCCCCATATGCTACGCCACAGCTTTGCAACGGCGTTATTAAACAACGGTGCAGATTTGCGGACTGTTCAAGAACT
TCTGGGTCATTCCAGTTTATCGACTACTCAAATCTACACGCATGTTACTAAAGAAAAACTACAAGAGAGCTACCGAAAAT
ATTTTCCACGCTCGACTGATGCTTAA

Upstream 100 bases:

>100_bases
GTGACTACGAAGAAACACCTCAAAAATAGTTTAAAAAACAAAATATTAATTGACGTTTACCTCTAACATTTGCTACAGTG
ACAAGTGTTGGAGGTTTTTT

Downstream 100 bases:

>100_bases
TTAAAAAGGAGAATACAAATGCCAGTAAAATTTGATGCGACAACCATTATTGCGATTAGTCATAATGGTGAAAATGCCAT
GGCCGGAGATGGCCAAGTAA

Product: tyrosine recombinase XerC subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MELISLFKQYLTVERQYSEKTVTAYLEDIDAFQKFLTDTGDKTDLLLVDRFDVNVYMSYLFDRHLARTSISRKVSALRSF
YRFLVKNDLVDKNPFELVQLKKQSDKLPHFFYEKEMNMLFEAVYQAEGAQKLRNIAILEVLYGTGMRVSECAALQWSDID
FSMQTILVLGKGNKERYVPFGRYAKEALQNYRKNEWEPFLSKYKQTHNFVFINHYAKPITTTGIEYILNQVITASSLNGK
IHPHMLRHSFATALLNNGADLRTVQELLGHSSLSTTQIYTHVTKEKLQESYRKYFPRSTDA

Sequences:

>Translated_301_residues
MELISLFKQYLTVERQYSEKTVTAYLEDIDAFQKFLTDTGDKTDLLLVDRFDVNVYMSYLFDRHLARTSISRKVSALRSF
YRFLVKNDLVDKNPFELVQLKKQSDKLPHFFYEKEMNMLFEAVYQAEGAQKLRNIAILEVLYGTGMRVSECAALQWSDID
FSMQTILVLGKGNKERYVPFGRYAKEALQNYRKNEWEPFLSKYKQTHNFVFINHYAKPITTTGIEYILNQVITASSLNGK
IHPHMLRHSFATALLNNGADLRTVQELLGHSSLSTTQIYTHVTKEKLQESYRKYFPRSTDA
>Mature_301_residues
MELISLFKQYLTVERQYSEKTVTAYLEDIDAFQKFLTDTGDKTDLLLVDRFDVNVYMSYLFDRHLARTSISRKVSALRSF
YRFLVKNDLVDKNPFELVQLKKQSDKLPHFFYEKEMNMLFEAVYQAEGAQKLRNIAILEVLYGTGMRVSECAALQWSDID
FSMQTILVLGKGNKERYVPFGRYAKEALQNYRKNEWEPFLSKYKQTHNFVFINHYAKPITTTGIEYILNQVITASSLNGK
IHPHMLRHSFATALLNNGADLRTVQELLGHSSLSTTQIYTHVTKEKLQESYRKYFPRSTDA

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily

Homologues:

Organism=Escherichia coli, GI1790244, Length=299, Percent_Identity=33.4448160535117, Blast_Score=164, Evalue=7e-42,
Organism=Escherichia coli, GI1789261, Length=296, Percent_Identity=35.472972972973, Blast_Score=161, Evalue=4e-41,
Organism=Escherichia coli, GI1790767, Length=182, Percent_Identity=30.2197802197802, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XERC_PEDPA (Q03FK2)

Other databases:

- EMBL:   CP000422
- RefSeq:   YP_804462.1
- ProteinModelPortal:   Q03FK2
- SMR:   Q03FK2
- STRING:   Q03FK2
- GeneID:   4417776
- GenomeReviews:   CP000422_GR
- KEGG:   ppe:PEPE_0964
- NMPDR:   fig|278197.10.peg.854
- eggNOG:   COG4974
- HOGENOM:   HBG727654
- OMA:   GIRYCLT
- PhylomeDB:   Q03FK2
- BioCyc:   PPEN278197:PEPE_0964-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01808
- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011931
- Gene3D:   G3DSA:1.10.150.130
- Gene3D:   G3DSA:1.10.443.10
- TIGRFAMs:   TIGR02224

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase; SSF56349 DNA_brk_join_enz; SSF47823 L_intgrse_like_N

EC number: NA

Molecular weight: Translated: 35160; Mature: 35160

Theoretical pI: Translated: 9.32; Mature: 9.32

Prosite motif: NA

Important sites: ACT_SITE 147-147 ACT_SITE 171-171 ACT_SITE 244-244 ACT_SITE 247-247 ACT_SITE 270-270 ACT_SITE 279-279

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELISLFKQYLTVERQYSEKTVTAYLEDIDAFQKFLTDTGDKTDLLLVDRFDVNVYMSYL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHH
FDRHLARTSISRKVSALRSFYRFLVKNDLVDKNPFELVQLKKQSDKLPHFFYEKEMNMLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHH
EAVYQAEGAQKLRNIAILEVLYGTGMRVSECAALQWSDIDFSMQTILVLGKGNKERYVPF
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCEECCCCCCEEEEEEEECCCCCCCCCH
GRYAKEALQNYRKNEWEPFLSKYKQTHNFVFINHYAKPITTTGIEYILNQVITASSLNGK
HHHHHHHHHHHHCCCCHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCC
IHPHMLRHSFATALLNNGADLRTVQELLGHSSLSTTQIYTHVTKEKLQESYRKYFPRSTD
CCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
A
C
>Mature Secondary Structure
MELISLFKQYLTVERQYSEKTVTAYLEDIDAFQKFLTDTGDKTDLLLVDRFDVNVYMSYL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHH
FDRHLARTSISRKVSALRSFYRFLVKNDLVDKNPFELVQLKKQSDKLPHFFYEKEMNMLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHH
EAVYQAEGAQKLRNIAILEVLYGTGMRVSECAALQWSDIDFSMQTILVLGKGNKERYVPF
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCEECCCCCCEEEEEEEECCCCCCCCCH
GRYAKEALQNYRKNEWEPFLSKYKQTHNFVFINHYAKPITTTGIEYILNQVITASSLNGK
HHHHHHHHHHHHCCCCHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCC
IHPHMLRHSFATALLNNGADLRTVQELLGHSSLSTTQIYTHVTKEKLQESYRKYFPRSTD
CCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA