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The map label for this gene is hslV

Identifier: 116492726

GI number: 116492726

Start: 966314

End: 966868

Strand: Reverse

Name: hslV

Synonym: PEPE_0963

Alternate gene names: 116492726

Gene position: 966868-966314 (Counterclockwise)

Preceding gene: 116492727

Following gene: 116492725

Centisome position: 52.77

GC content: 40.54

Gene sequence:

>555_bases
ATGCCAGTAAAATTTGATGCGACAACCATTATTGCGATTAGTCATAATGGTGAAAATGCCATGGCCGGAGATGGCCAAGT
AACAATGGGTGAAAAATTTATTATGAAAGGGACTGCCCGCAAGGTTCGTCGAATTTATGATGGAAAGGTCATTGTTGGTT
TTGCCGGAAGTGTTGCTGACGCTTTTAACCTTGAAGAAAAATTTGAAAAGAAGCTTTCTGAATATAGTGGGAATTTACAA
AGAGCTTCTGTTGAACTAGCCAAAATTTGGCGTGGTGATCAACAACTTCAAAAATTAGAAGCTATGTTAATTGTTATGGA
CGAAAAAGAGATGTATCTTGTTTCTGGAAGTGGAGAAGTTATCGCTCCTGATGACGGAATCTTAGCGATTGGTTCAGGCG
GTAACTTTGCGCTGGCCGCAGCTAAAGCCCTCAAGAAGCATGCTACGCAAGTTAGTGCGAAAGAAATGGCTAAAACTGCG
ATTAACGTTGCGGGTGATATTGATATCTTTACGAACCACAACGTTATTGCATTGGATTTCAAGGAGGAAGACTAA

Upstream 100 bases:

>100_bases
TACTCAAATCTACACGCATGTTACTAAAGAAAAACTACAAGAGAGCTACCGAAAATATTTTCCACGCTCGACTGATGCTT
AATTAAAAAGGAGAATACAA

Downstream 100 bases:

>100_bases
ATCATGCAATATAATTTAACACCACAAGAAATCGTTCAAGAATTAGATCAATTTGTAATTGGTCAAAAAAGTGCTAAGCG
CGCAGTAGCAGTGGCATTAC

Product: ATP-dependent protease peptidase subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 184; Mature: 183

Protein sequence:

>184_residues
MPVKFDATTIIAISHNGENAMAGDGQVTMGEKFIMKGTARKVRRIYDGKVIVGFAGSVADAFNLEEKFEKKLSEYSGNLQ
RASVELAKIWRGDQQLQKLEAMLIVMDEKEMYLVSGSGEVIAPDDGILAIGSGGNFALAAAKALKKHATQVSAKEMAKTA
INVAGDIDIFTNHNVIALDFKEED

Sequences:

>Translated_184_residues
MPVKFDATTIIAISHNGENAMAGDGQVTMGEKFIMKGTARKVRRIYDGKVIVGFAGSVADAFNLEEKFEKKLSEYSGNLQ
RASVELAKIWRGDQQLQKLEAMLIVMDEKEMYLVSGSGEVIAPDDGILAIGSGGNFALAAAKALKKHATQVSAKEMAKTA
INVAGDIDIFTNHNVIALDFKEED
>Mature_183_residues
PVKFDATTIIAISHNGENAMAGDGQVTMGEKFIMKGTARKVRRIYDGKVIVGFAGSVADAFNLEEKFEKKLSEYSGNLQR
ASVELAKIWRGDQQLQKLEAMLIVMDEKEMYLVSGSGEVIAPDDGILAIGSGGNFALAAAKALKKHATQVSAKEMAKTAI
NVAGDIDIFTNHNVIALDFKEED

Specific function: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery

COG id: COG5405

COG function: function code O; ATP-dependent protease HslVU (ClpYQ), peptidase subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase T1B family. HslV subfamily

Homologues:

Organism=Escherichia coli, GI1790367, Length=166, Percent_Identity=52.4096385542169, Blast_Score=177, Evalue=4e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HSLV_PEDPA (Q03FK3)

Other databases:

- EMBL:   CP000422
- RefSeq:   YP_804461.1
- ProteinModelPortal:   Q03FK3
- SMR:   Q03FK3
- STRING:   Q03FK3
- MEROPS:   T01.007
- GeneID:   4417775
- GenomeReviews:   CP000422_GR
- KEGG:   ppe:PEPE_0963
- NMPDR:   fig|278197.10.peg.853
- eggNOG:   COG5405
- HOGENOM:   HBG288822
- OMA:   AADICVY
- PhylomeDB:   Q03FK3
- ProtClustDB:   PRK05456
- BioCyc:   PPEN278197:PEPE_0963-MONOMER
- HAMAP:   MF_00248
- InterPro:   IPR022281
- InterPro:   IPR001353
- TIGRFAMs:   TIGR03692

Pfam domain/function: PF00227 Proteasome

EC number: 3.4.25.-

Molecular weight: Translated: 19868; Mature: 19737

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: NA

Important sites: ACT_SITE 8-8

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVKFDATTIIAISHNGENAMAGDGQVTMGEKFIMKGTARKVRRIYDGKVIVGFAGSVAD
CCEEECCEEEEEEEECCCCCCCCCCEEEECCCEEECHHHHHHHHHHCCEEEEEECCCHHH
AFNLEEKFEKKLSEYSGNLQRASVELAKIWRGDQQLQKLEAMLIVMDEKEMYLVSGSGEV
HCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHEEEEEECCCEEEEEECCCCE
IAPDDGILAIGSGGNFALAAAKALKKHATQVSAKEMAKTAINVAGDIDIFTNHNVIALDF
ECCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEE
KEED
CCCC
>Mature Secondary Structure 
PVKFDATTIIAISHNGENAMAGDGQVTMGEKFIMKGTARKVRRIYDGKVIVGFAGSVAD
CEEECCEEEEEEEECCCCCCCCCCEEEECCCEEECHHHHHHHHHHCCEEEEEECCCHHH
AFNLEEKFEKKLSEYSGNLQRASVELAKIWRGDQQLQKLEAMLIVMDEKEMYLVSGSGEV
HCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHEEEEEECCCEEEEEECCCCE
IAPDDGILAIGSGGNFALAAAKALKKHATQVSAKEMAKTAINVAGDIDIFTNHNVIALDF
ECCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEE
KEED
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA