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The map label for this gene is ponA [H]

Identifier: 116492696

GI number: 116492696

Start: 932540

End: 934849

Strand: Reverse

Name: ponA [H]

Synonym: PEPE_0931

Alternate gene names: 116492696

Gene position: 934849-932540 (Counterclockwise)

Preceding gene: 116492697

Following gene: 116492692

Centisome position: 51.02

GC content: 38.66

Gene sequence:

>2310_bases
ATGAACAACGGAAATCAGTACCAAAATCGACCCATGCGACGAACGCAACATTCGAAAATGGGTAAACACCCTAAACCCAA
CCGACATTCTTCCTTAATTAAGAAGTTATTGTTGGCAGCAGTAGCAGTTTTTGTAGCGATGATTATTTTCGGTGGTGGGC
TCTTTATGTACTATGCTCAAAGCGCTCCTAAAATCACGGAAGCTAAATTATCGAGTGATAACGCCACTGTAATTTACGAT
AAAGACGGTAAAGTATTAACTCGTCTGGGATCACAAAATCGTGAATATGTTAAAAAAGACAAGATTCCAAAGACTTTAAA
GAACGCGATTGTTTCGATTGAAGATCGTCGCTTCTACAAGAATAACGGTGTGGATCCCATTCGTATTGTAGGAGCAACAG
TTGCTAACCTTACAGGATCTTCTTTAGGTCTACAAGGCGCTAGTACCTTAACTCAGCAATTGGTTAAATTATCTGTATTC
TCTACGGACGCATCAGATCGAACTTTAAGAGTTAAGGCTCAAGAAGCTTGGTTAGCTTTGAAGGTTGATAAGAAATATAG
TAAAGATCAGATTCTTGAATTCTATATTAATAAGGTTTACATGGGTAATGGTATTTACGGTATGCAAACAGCGGCTAAGT
ATTACTTTGGTAAGTCGCTTGAAAAATTAGATTTAGCTCAATTGGCTTTATTAGCCGGTATGCCACAATCCCCTACTAAT
TACGATCCAATTAGTAACCCTAAGTATGCTAAGTCCCGTCGAGACACGGTTCTTCAAGCCATGGCTTCTAATAAAGTAGT
TACTCAAGCTCAAGCAACAGAAGCGCAAAAAGAAAGTATCTCTGATGGACTTTCAGAGACCCATGAAACTTCAACTAACT
CAGCTAAGAAAAACAAGATTATTGATCCTTATATCAAACAAGTGTTACAAGACCTTTCTGATAAAGGATTTGATACTGCT
AAGGGTGGTTTGAAAGTTTATACTAACATGGACTATGCGGCTCAAAAGAAACTTTACGATTTAGCAAATAATGACCAAAC
GGTACAATTTAACGATGATGAGCTTCAAATTGGTGCCACGTTAGTCAATAGTAAAAATGGAAAAATCGCCGCGATGATTG
GTGGACGTAAAACTGGTGATGTTACTTATGGTTTAAACCGAGCTGTTCAAACTGACCGTAGCTCTGGTTCAACCGCTAAA
CCACTAATGGATTACGGTCCCGCATTTGAATATCTGAAGTGGTCGACGTATCGAAAAGTTAAAGATACTCCATTTACTTA
TCCTGGAACAGACACAAAACTTTATGACTTTGATCATAAGTTTAAGGGAACAATGACAGTACGAGATGCGTTAATTCAAT
CTCGAAACGTTCCTGCGATTCGAACCTTACAAGATGTCGGCATTTCCAAGGCAACAACTTTCCTTGAAGGTTTAGGAATT
ACAAGTAAGGAACCCTATAACCTTAATAATGGAATTGGGTTGTACATTTCTACACTTCAAACAGCCGCTGCCTATGCTGC
CTTTGCTAATGATGGTATCTATCACAAGCCAACTTATATTAATAAAATTGATACTAATAGCGGTAAAACCTATACCTACA
AGTCTAAAGGTGTTCGTGCAATGAGTAAGGCTACAGCTTTCTTGATGACATCGATTCTAAAAGGAGTCACAACTGACTCG
CAAGGTTCTGGTACTGCAGCTAATATTACTGGCATGAATATGGCTTCTAAAACTGGTACCGTAGCCTATTCGAAGAAAGC
TACCGAAGCAAATGACATTCCAAGTTCAGCATCTAGTGATTCTTGGATGGCTGGTTATACCAAGGATTATTCGTTAGCTG
TTTGGACTGGTTATGATCATCCAAATACTTCGACTGGTTACCTAACTCAATCACAAACTGAGTTAGCTCAGTATTATTGG
AAGTATATGATTTATTACCTATCTCAATACTCTTCCAACGAAGACTGGACCATGCCTTCAACAGTTGGTAAAAAAGGTAC
TAACCAGTATTATCAAATTGGTGAAGATTATGATGAGACTGGCAAGAGTGATGAATACTCTAAGAACAACAGTAGCAGTA
GCTGGTCAAGTTATTCTAGCAAGCATTCAAACTCTTCTTATAGTAGTCGTTATAGTAGTTCTGATGCTGACGACGATGAT
AGTAGCAGCAACGATACTTCTTCTGAAGATAGCTCCAGCACACCATCCTATAGCTCTGACGTAAGCAGTAATGATACGAC
AAGTGATAGCACTTCTACTACCACTTCTGCTTCAACAACTTCTACTAGCTCTGCTAGTGATTCTGAATAA

Upstream 100 bases:

>100_bases
GGAATACCAAATGAATCCTTTAATTCCATACCTAAAAGCGGTTGATAAAATTATAGAGAATTTATAAAAAATCGATTTTC
TAACAGCAAGGAGATTATCT

Downstream 100 bases:

>100_bases
CTAAAAAAGATCATCTCAATCAATGAGATGATCTTTTTTAGTTGTCTTTAGTTAATTTAACCAGTGGAATTTGGATATGC
TTCTTTTGATTATCTTTATT

Product: membrane carboxypeptidase (penicillin-binding protein)

Products: NA

Alternate protein names: PBP-1A [H]

Number of amino acids: Translated: 769; Mature: 769

Protein sequence:

>769_residues
MNNGNQYQNRPMRRTQHSKMGKHPKPNRHSSLIKKLLLAAVAVFVAMIIFGGGLFMYYAQSAPKITEAKLSSDNATVIYD
KDGKVLTRLGSQNREYVKKDKIPKTLKNAIVSIEDRRFYKNNGVDPIRIVGATVANLTGSSLGLQGASTLTQQLVKLSVF
STDASDRTLRVKAQEAWLALKVDKKYSKDQILEFYINKVYMGNGIYGMQTAAKYYFGKSLEKLDLAQLALLAGMPQSPTN
YDPISNPKYAKSRRDTVLQAMASNKVVTQAQATEAQKESISDGLSETHETSTNSAKKNKIIDPYIKQVLQDLSDKGFDTA
KGGLKVYTNMDYAAQKKLYDLANNDQTVQFNDDELQIGATLVNSKNGKIAAMIGGRKTGDVTYGLNRAVQTDRSSGSTAK
PLMDYGPAFEYLKWSTYRKVKDTPFTYPGTDTKLYDFDHKFKGTMTVRDALIQSRNVPAIRTLQDVGISKATTFLEGLGI
TSKEPYNLNNGIGLYISTLQTAAAYAAFANDGIYHKPTYINKIDTNSGKTYTYKSKGVRAMSKATAFLMTSILKGVTTDS
QGSGTAANITGMNMASKTGTVAYSKKATEANDIPSSASSDSWMAGYTKDYSLAVWTGYDHPNTSTGYLTQSQTELAQYYW
KYMIYYLSQYSSNEDWTMPSTVGKKGTNQYYQIGEDYDETGKSDEYSKNNSSSSWSSYSSKHSNSSYSSRYSSSDADDDD
SSSNDTSSEDSSSTPSYSSDVSSNDTTSDSTSTTTSASTTSTSSASDSE

Sequences:

>Translated_769_residues
MNNGNQYQNRPMRRTQHSKMGKHPKPNRHSSLIKKLLLAAVAVFVAMIIFGGGLFMYYAQSAPKITEAKLSSDNATVIYD
KDGKVLTRLGSQNREYVKKDKIPKTLKNAIVSIEDRRFYKNNGVDPIRIVGATVANLTGSSLGLQGASTLTQQLVKLSVF
STDASDRTLRVKAQEAWLALKVDKKYSKDQILEFYINKVYMGNGIYGMQTAAKYYFGKSLEKLDLAQLALLAGMPQSPTN
YDPISNPKYAKSRRDTVLQAMASNKVVTQAQATEAQKESISDGLSETHETSTNSAKKNKIIDPYIKQVLQDLSDKGFDTA
KGGLKVYTNMDYAAQKKLYDLANNDQTVQFNDDELQIGATLVNSKNGKIAAMIGGRKTGDVTYGLNRAVQTDRSSGSTAK
PLMDYGPAFEYLKWSTYRKVKDTPFTYPGTDTKLYDFDHKFKGTMTVRDALIQSRNVPAIRTLQDVGISKATTFLEGLGI
TSKEPYNLNNGIGLYISTLQTAAAYAAFANDGIYHKPTYINKIDTNSGKTYTYKSKGVRAMSKATAFLMTSILKGVTTDS
QGSGTAANITGMNMASKTGTVAYSKKATEANDIPSSASSDSWMAGYTKDYSLAVWTGYDHPNTSTGYLTQSQTELAQYYW
KYMIYYLSQYSSNEDWTMPSTVGKKGTNQYYQIGEDYDETGKSDEYSKNNSSSSWSSYSSKHSNSSYSSRYSSSDADDDD
SSSNDTSSEDSSSTPSYSSDVSSNDTTSDSTSTTTSASTTSTSSASDSE
>Mature_769_residues
MNNGNQYQNRPMRRTQHSKMGKHPKPNRHSSLIKKLLLAAVAVFVAMIIFGGGLFMYYAQSAPKITEAKLSSDNATVIYD
KDGKVLTRLGSQNREYVKKDKIPKTLKNAIVSIEDRRFYKNNGVDPIRIVGATVANLTGSSLGLQGASTLTQQLVKLSVF
STDASDRTLRVKAQEAWLALKVDKKYSKDQILEFYINKVYMGNGIYGMQTAAKYYFGKSLEKLDLAQLALLAGMPQSPTN
YDPISNPKYAKSRRDTVLQAMASNKVVTQAQATEAQKESISDGLSETHETSTNSAKKNKIIDPYIKQVLQDLSDKGFDTA
KGGLKVYTNMDYAAQKKLYDLANNDQTVQFNDDELQIGATLVNSKNGKIAAMIGGRKTGDVTYGLNRAVQTDRSSGSTAK
PLMDYGPAFEYLKWSTYRKVKDTPFTYPGTDTKLYDFDHKFKGTMTVRDALIQSRNVPAIRTLQDVGISKATTFLEGLGI
TSKEPYNLNNGIGLYISTLQTAAAYAAFANDGIYHKPTYINKIDTNSGKTYTYKSKGVRAMSKATAFLMTSILKGVTTDS
QGSGTAANITGMNMASKTGTVAYSKKATEANDIPSSASSDSWMAGYTKDYSLAVWTGYDHPNTSTGYLTQSQTELAQYYW
KYMIYYLSQYSSNEDWTMPSTVGKKGTNQYYQIGEDYDETGKSDEYSKNNSSSSWSSYSSKHSNSSYSSRYSSSDADDDD
SSSNDTSSEDSSSTPSYSSDVSSNDTTSDSTSTTTSASTTSTSSASDSE

Specific function: Cell wall formation [H]

COG id: COG0744

COG function: function code M; Membrane carboxypeptidase (penicillin-binding protein)

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transpeptidase family [H]

Homologues:

Organism=Escherichia coli, GI1786343, Length=569, Percent_Identity=29.3497363796134, Blast_Score=188, Evalue=1e-48,
Organism=Escherichia coli, GI87082258, Length=322, Percent_Identity=31.3664596273292, Blast_Score=164, Evalue=3e-41,
Organism=Escherichia coli, GI1788867, Length=579, Percent_Identity=25.73402417962, Blast_Score=152, Evalue=1e-37,
Organism=Escherichia coli, GI1789601, Length=231, Percent_Identity=27.7056277056277, Blast_Score=85, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001264
- InterPro:   IPR011816
- InterPro:   IPR001460 [H]

Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]

EC number: 2.4.2.-; 3.4.-.-

Molecular weight: Translated: 84366; Mature: 84366

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNGNQYQNRPMRRTQHSKMGKHPKPNRHSSLIKKLLLAAVAVFVAMIIFGGGLFMYYAQ
CCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEC
SAPKITEAKLSSDNATVIYDKDGKVLTRLGSQNREYVKKDKIPKTLKNAIVSIEDRRFYK
CCCCCCHHEECCCCEEEEECCCCHHHHHHCCCCHHHHHHHCCHHHHHHHHEEHHCCHHHH
NNGVDPIRIVGATVANLTGSSLGLQGASTLTQQLVKLSVFSTDASDRTLRVKAQEAWLAL
CCCCCCEEEEHHHHHHCCCCCCCCCHHHHHHHHHHHHHHEECCCCCCEEEEEEECCEEEE
KVDKKYSKDQILEFYINKVYMGNGIYGMQTAAKYYFGKSLEKLDLAQLALLAGMPQSPTN
EECCCCCHHHHHHHHHHHEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCC
YDPISNPKYAKSRRDTVLQAMASNKVVTQAQATEAQKESISDGLSETHETSTNSAKKNKI
CCCCCCCHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCC
IDPYIKQVLQDLSDKGFDTAKGGLKVYTNMDYAAQKKLYDLANNDQTVQFNDDELQIGAT
CCHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCCEEEECCCCEEEEEE
LVNSKNGKIAAMIGGRKTGDVTYGLNRAVQTDRSSGSTAKPLMDYGPAFEYLKWSTYRKV
EEECCCCEEEEEECCCCCCCEECCCHHHHHCCCCCCCCCCCHHHCCCHHHHHHHHHHHHC
KDTPFTYPGTDTKLYDFDHKFKGTMTVRDALIQSRNVPAIRTLQDVGISKATTFLEGLGI
CCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHCCC
TSKEPYNLNNGIGLYISTLQTAAAYAAFANDGIYHKPTYINKIDTNSGKTYTYKSKGVRA
CCCCCCCCCCCCEEEHHHHHHHHHHHHHHCCCCEECCCEEEEEECCCCCEEEECCCCCHH
MSKATAFLMTSILKGVTTDSQGSGTAANITGMNMASKTGTVAYSKKATEANDIPSSASSD
HHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCEEECCCCCCCCCCCCCCCCC
SWMAGYTKDYSLAVWTGYDHPNTSTGYLTQSQTELAQYYWKYMIYYLSQYSSNEDWTMPS
CEEECCCCCCEEEEEECCCCCCCCCCCEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
TVGKKGTNQYYQIGEDYDETGKSDEYSKNNSSSSWSSYSSKHSNSSYSSRYSSSDADDDD
HHCCCCCCCHHCCCCCHHHCCCCCCCCCCCCCCCHHHHHHCCCCCCHHHCCCCCCCCCCC
SSSNDTSSEDSSSTPSYSSDVSSNDTTSDSTSTTTSASTTSTSSASDSE
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNNGNQYQNRPMRRTQHSKMGKHPKPNRHSSLIKKLLLAAVAVFVAMIIFGGGLFMYYAQ
CCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEC
SAPKITEAKLSSDNATVIYDKDGKVLTRLGSQNREYVKKDKIPKTLKNAIVSIEDRRFYK
CCCCCCHHEECCCCEEEEECCCCHHHHHHCCCCHHHHHHHCCHHHHHHHHEEHHCCHHHH
NNGVDPIRIVGATVANLTGSSLGLQGASTLTQQLVKLSVFSTDASDRTLRVKAQEAWLAL
CCCCCCEEEEHHHHHHCCCCCCCCCHHHHHHHHHHHHHHEECCCCCCEEEEEEECCEEEE
KVDKKYSKDQILEFYINKVYMGNGIYGMQTAAKYYFGKSLEKLDLAQLALLAGMPQSPTN
EECCCCCHHHHHHHHHHHEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCC
YDPISNPKYAKSRRDTVLQAMASNKVVTQAQATEAQKESISDGLSETHETSTNSAKKNKI
CCCCCCCHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCC
IDPYIKQVLQDLSDKGFDTAKGGLKVYTNMDYAAQKKLYDLANNDQTVQFNDDELQIGAT
CCHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCCEEEECCCCEEEEEE
LVNSKNGKIAAMIGGRKTGDVTYGLNRAVQTDRSSGSTAKPLMDYGPAFEYLKWSTYRKV
EEECCCCEEEEEECCCCCCCEECCCHHHHHCCCCCCCCCCCHHHCCCHHHHHHHHHHHHC
KDTPFTYPGTDTKLYDFDHKFKGTMTVRDALIQSRNVPAIRTLQDVGISKATTFLEGLGI
CCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHCCC
TSKEPYNLNNGIGLYISTLQTAAAYAAFANDGIYHKPTYINKIDTNSGKTYTYKSKGVRA
CCCCCCCCCCCCEEEHHHHHHHHHHHHHHCCCCEECCCEEEEEECCCCCEEEECCCCCHH
MSKATAFLMTSILKGVTTDSQGSGTAANITGMNMASKTGTVAYSKKATEANDIPSSASSD
HHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCEEECCCCCCCCCCCCCCCCC
SWMAGYTKDYSLAVWTGYDHPNTSTGYLTQSQTELAQYYWKYMIYYLSQYSSNEDWTMPS
CEEECCCCCCEEEEEECCCCCCCCCCCEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
TVGKKGTNQYYQIGEDYDETGKSDEYSKNNSSSSWSSYSSKHSNSSYSSRYSSSDADDDD
HHCCCCCCCHHCCCCCHHHCCCCCCCCCCCCCCCHHHHHHCCCCCCHHHCCCCCCCCCCC
SSSNDTSSEDSSSTPSYSSDVSSNDTTSDSTSTTTSASTTSTSSASDSE
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1396576; 11463916 [H]