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The map label for this gene is 116492420

Identifier: 116492420

GI number: 116492420

Start: 692419

End: 693078

Strand: Reverse

Name: 116492420

Synonym: PEPE_0650

Alternate gene names: NA

Gene position: 693078-692419 (Counterclockwise)

Preceding gene: 116492425

Following gene: 116492418

Centisome position: 37.82

GC content: 34.55

Gene sequence:

>660_bases
ATGGTGATAATTACAGCAGGAATGATCGGCGTCGGTAAAACTACATTAACAGGGAAAATTGCTGACTACTATGGAACAAA
GGCGTTCTACGAACCAGTTGGAGACAATCCCGTTTTACCACTCTATTATTCTGACCAAAAAAGTTATGGATTCTTACTTC
AAATTTATTTTTTGAATAAACGATTCCAAATGATCAAAAAGGCTTTGACTGATGATAATAATGTATTAGACCGTTCAATC
TACGAAGATGCTCTATTCACACGTGAAAACAACAAAGAAGGTAACATTACGGATACTGAATTTGAAGTTTACATGAACCT
TCTTGATAACATGATGAGTGAGCTTCAAAATCTACCTAAGAAAGCACCAGATTTGATGGTCTATGCTGAAACAGATTTTG
ATACCATCCTCTATCGTATTCGTAAACGTGGGCGTGACTATGAACAATTCGATAACAATCCTGAATTGGAATCTTACTAC
TATAAGATGTGGTCAGCTTACAAGACATGGTACGAAGAATATGATGTTGGTCCTAAAATGAAAATTGATTTACAAAAGTA
CGATTTAAGTAACGAAGAAAACGTTAAAATCATCCTTAAACAAATCAATGCTAAACTTAAAGAAGTTCGGGTTGAAGAAC
CTATGCATAAAGCAATCTAA

Upstream 100 bases:

>100_bases
TTGCGCTCCAATTCTTTATACAATATGTTGTGGCTGTTTAAAGATTTAGGATTTATTAATACTAGATTTCGGCAAAAAAA
AATGGAAAAGGGAGCATTTT

Downstream 100 bases:

>100_bases
TTTAAAATGACCTCAATTGTCGTTCCACTCTAGTTTAAAACTAAAGTGCCGACAATTGAGGTCATTTTGTTTATCATTTA
ATTTTTAACAATCATAACGT

Product: deoxynucleoside kinase

Products: NA

Alternate protein names: DGK; DGUO kinase; Deoxynucleoside kinase complex I F-component [H]

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MVIITAGMIGVGKTTLTGKIADYYGTKAFYEPVGDNPVLPLYYSDQKSYGFLLQIYFLNKRFQMIKKALTDDNNVLDRSI
YEDALFTRENNKEGNITDTEFEVYMNLLDNMMSELQNLPKKAPDLMVYAETDFDTILYRIRKRGRDYEQFDNNPELESYY
YKMWSAYKTWYEEYDVGPKMKIDLQKYDLSNEENVKIILKQINAKLKEVRVEEPMHKAI

Sequences:

>Translated_219_residues
MVIITAGMIGVGKTTLTGKIADYYGTKAFYEPVGDNPVLPLYYSDQKSYGFLLQIYFLNKRFQMIKKALTDDNNVLDRSI
YEDALFTRENNKEGNITDTEFEVYMNLLDNMMSELQNLPKKAPDLMVYAETDFDTILYRIRKRGRDYEQFDNNPELESYY
YKMWSAYKTWYEEYDVGPKMKIDLQKYDLSNEENVKIILKQINAKLKEVRVEEPMHKAI
>Mature_219_residues
MVIITAGMIGVGKTTLTGKIADYYGTKAFYEPVGDNPVLPLYYSDQKSYGFLLQIYFLNKRFQMIKKALTDDNNVLDRSI
YEDALFTRENNKEGNITDTEFEVYMNLLDNMMSELQNLPKKAPDLMVYAETDFDTILYRIRKRGRDYEQFDNNPELESYY
YKMWSAYKTWYEEYDVGPKMKIDLQKYDLSNEENVKIILKQINAKLKEVRVEEPMHKAI

Specific function: DGK/DAK plays an essential role in generating the deoxyribonucleotide precursors, dGTP and dATP, for DNA metabolism [H]

COG id: COG1428

COG function: function code F; Deoxynucleoside kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DCK/DGK family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002624 [H]

Pfam domain/function: PF01712 dNK [H]

EC number: =2.7.1.113 [H]

Molecular weight: Translated: 25880; Mature: 25880

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVIITAGMIGVGKTTLTGKIADYYGTKAFYEPVGDNPVLPLYYSDQKSYGFLLQIYFLNK
CEEEEECCEECCCCHHHCHHHHHHCCHHHCCCCCCCCEEEEEECCCCCCCEEEEEEHHHH
RFQMIKKALTDDNNVLDRSIYEDALFTRENNKEGNITDTEFEVYMNLLDNMMSELQNLPK
HHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
KAPDLMVYAETDFDTILYRIRKRGRDYEQFDNNPELESYYYKMWSAYKTWYEEYDVGPKM
CCCCEEEEEECCHHHHHHHHHHHCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCE
KIDLQKYDLSNEENVKIILKQINAKLKEVRVEEPMHKAI
EEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHCC
>Mature Secondary Structure
MVIITAGMIGVGKTTLTGKIADYYGTKAFYEPVGDNPVLPLYYSDQKSYGFLLQIYFLNK
CEEEEECCEECCCCHHHCHHHHHHCCHHHCCCCCCCCEEEEEECCCCCCCEEEEEEHHHH
RFQMIKKALTDDNNVLDRSIYEDALFTRENNKEGNITDTEFEVYMNLLDNMMSELQNLPK
HHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
KAPDLMVYAETDFDTILYRIRKRGRDYEQFDNNPELESYYYKMWSAYKTWYEEYDVGPKM
CCCCEEEEEECCHHHHHHHHHHHCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCE
KIDLQKYDLSNEENVKIILKQINAKLKEVRVEEPMHKAI
EEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7896798; 8172906 [H]