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The map label for this gene is glmM

Identifier: 116492279

GI number: 116492279

Start: 528312

End: 529670

Strand: Direct

Name: glmM

Synonym: PEPE_0477

Alternate gene names: 116492279

Gene position: 528312-529670 (Clockwise)

Preceding gene: 116492278

Following gene: 116492280

Centisome position: 28.83

GC content: 40.32

Gene sequence:

>1359_bases
ATGAAATTAAAGTATTTTGGTACTGACGGAGTTCGAGGAATTGCAAATGAAACATTGACTCCAGAATTAGCGTTTCAATT
AGGCCGTGCTGGTGGTTATGTTTTAACTAAGCATGCTAAAGATGATGAACAACCACGGGTTTTAGTTTCAAGAGATACCC
GAATTTCAGGACAATTGTTAAAACATGCATTGATCTCAGGCTTACTTTCAGTCGGCATTGAAGTTATGGACATGGGAATT
GTTACAACTCCTGGTGTGGCTTATCTTGTTCGTAAACAAGAAGCTGACGCTGGTGTAATGATTACTGCTTCACATAATCC
GGTTCAAGATAACGGAATCAAGTTCTTTGGTTCAGATGGTTACAAGCTATCAGATGAACTTGAAGCTGAAATCGAAGTAC
TTTTAGATGCTGATAAAGACAACTTACCTCGTCCTTCATCTACTGGACTAGGTTCAGTGACTGATTATCCAGAAGGTGGA
TTAAACTATACGGCCTTTCTTGAACAAACTATTCCCGATGACTTGGAAGGTTTGCATATCGCAATTGATGCTGCTAATGG
AGCAACCAGTAGCTACGTTTCACAAATATTTGCGGACTTAAATACTGAGTTTGATACGATGGCAACAAATCCAGATGGTT
TGAACATCAACGCTGGAGTTGGTTCTACTCATCCTGAAGGATTGGCTAAGTTTGTGGTCGAAAAAGGCGCTGATATGGGA
GTTGCTTTTGATGGCGATGGAGACCGTTGTATTGCCGTTGATGAATTAGGTAATATCGTTGACGGTGACAAGATTATGTA
TATCTGTGGTAAATTCTTGAGCGAACGCGGACGTTTGAAAGACGATACTGTGGTTACAACCGTGATGAGTAATCTAGGAC
TATATAAGGCTCTAGAAGCTAATGATATGCACTCGGTTAAGACCCAAGTTGGTGACCGCTATGTGGTTGAAGAAATGCTT
AAAGACGGATATAACCTTGGTGGTGAACAGTCCGGACACATTGTCTTCTTAGACCACAATACTACTGGAGATGGTATGTT
AACCGCCATTCAATTGATGTACGTGGTTAAACAAACTGGTAAAAAGTTGTCTGAGTTAGCTGCTGATGTGACAACTTACC
CTCAAAAATTAGTTAACGTTCGAGTACAAGATAAGAAGCTAGCACTTGAAAATCAAGCAATTAAAGATATCATTGAAAAA
GTTGAAAATGAAATGAACGGTGAAGGTCGAGTTCTAGTGCGCCCTTCAGGGACTGAAGACCTACTTCGTATTATGGCCGA
AGCTCCTACAAAAGAAGCAGTTGGTCAATATGTTGATCGAATTGTTGCTGTAGTTCAAAGTGAAGTTGGCGTGGATTAA

Upstream 100 bases:

>100_bases
TCAAACGACCTCAGATAGTGCAACTTCCGACAGTACAAGCACATCTGATGCTAGCGGAAACACAGATACACAGGTGAATT
AACAAAGGAGATTATTAACA

Downstream 100 bases:

>100_bases
TTAGTTGAATTCAACTTCTACAACTGAATAAATTTAAAAAACTATGCTATTTTGCAAAAAATGGCATAGTTTTTTTATAC
GCGAAAAGCATTGCTACTAT

Product: phosphoglucosamine mutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MKLKYFGTDGVRGIANETLTPELAFQLGRAGGYVLTKHAKDDEQPRVLVSRDTRISGQLLKHALISGLLSVGIEVMDMGI
VTTPGVAYLVRKQEADAGVMITASHNPVQDNGIKFFGSDGYKLSDELEAEIEVLLDADKDNLPRPSSTGLGSVTDYPEGG
LNYTAFLEQTIPDDLEGLHIAIDAANGATSSYVSQIFADLNTEFDTMATNPDGLNINAGVGSTHPEGLAKFVVEKGADMG
VAFDGDGDRCIAVDELGNIVDGDKIMYICGKFLSERGRLKDDTVVTTVMSNLGLYKALEANDMHSVKTQVGDRYVVEEML
KDGYNLGGEQSGHIVFLDHNTTGDGMLTAIQLMYVVKQTGKKLSELAADVTTYPQKLVNVRVQDKKLALENQAIKDIIEK
VENEMNGEGRVLVRPSGTEDLLRIMAEAPTKEAVGQYVDRIVAVVQSEVGVD

Sequences:

>Translated_452_residues
MKLKYFGTDGVRGIANETLTPELAFQLGRAGGYVLTKHAKDDEQPRVLVSRDTRISGQLLKHALISGLLSVGIEVMDMGI
VTTPGVAYLVRKQEADAGVMITASHNPVQDNGIKFFGSDGYKLSDELEAEIEVLLDADKDNLPRPSSTGLGSVTDYPEGG
LNYTAFLEQTIPDDLEGLHIAIDAANGATSSYVSQIFADLNTEFDTMATNPDGLNINAGVGSTHPEGLAKFVVEKGADMG
VAFDGDGDRCIAVDELGNIVDGDKIMYICGKFLSERGRLKDDTVVTTVMSNLGLYKALEANDMHSVKTQVGDRYVVEEML
KDGYNLGGEQSGHIVFLDHNTTGDGMLTAIQLMYVVKQTGKKLSELAADVTTYPQKLVNVRVQDKKLALENQAIKDIIEK
VENEMNGEGRVLVRPSGTEDLLRIMAEAPTKEAVGQYVDRIVAVVQSEVGVD
>Mature_452_residues
MKLKYFGTDGVRGIANETLTPELAFQLGRAGGYVLTKHAKDDEQPRVLVSRDTRISGQLLKHALISGLLSVGIEVMDMGI
VTTPGVAYLVRKQEADAGVMITASHNPVQDNGIKFFGSDGYKLSDELEAEIEVLLDADKDNLPRPSSTGLGSVTDYPEGG
LNYTAFLEQTIPDDLEGLHIAIDAANGATSSYVSQIFADLNTEFDTMATNPDGLNINAGVGSTHPEGLAKFVVEKGADMG
VAFDGDGDRCIAVDELGNIVDGDKIMYICGKFLSERGRLKDDTVVTTVMSNLGLYKALEANDMHSVKTQVGDRYVVEEML
KDGYNLGGEQSGHIVFLDHNTTGDGMLTAIQLMYVVKQTGKKLSELAADVTTYPQKLVNVRVQDKKLALENQAIKDIIEK
VENEMNGEGRVLVRPSGTEDLLRIMAEAPTKEAVGQYVDRIVAVVQSEVGVD

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family

Homologues:

Organism=Escherichia coli, GI1789566, Length=448, Percent_Identity=39.7321428571429, Blast_Score=309, Evalue=2e-85,
Organism=Escherichia coli, GI1788361, Length=454, Percent_Identity=27.0925110132159, Blast_Score=117, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLMM_PEDPA (Q03GV0)

Other databases:

- EMBL:   CP000422
- RefSeq:   YP_804014.1
- ProteinModelPortal:   Q03GV0
- SMR:   Q03GV0
- STRING:   Q03GV0
- GeneID:   4418340
- GenomeReviews:   CP000422_GR
- KEGG:   ppe:PEPE_0477
- NMPDR:   fig|278197.10.peg.444
- eggNOG:   COG1109
- HOGENOM:   HBG644964
- OMA:   EEAGINS
- PhylomeDB:   Q03GV0
- ProtClustDB:   PRK14316
- BioCyc:   PPEN278197:PEPE_0477-MONOMER
- HAMAP:   MF_01554_B
- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841
- InterPro:   IPR018247
- InterPro:   IPR006352
- Gene3D:   G3DSA:3.40.120.10
- PRINTS:   PR00509
- TIGRFAMs:   TIGR01455

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV; SSF53738 A-D-PHexomutase_a/b/a-I/II/III

EC number: =5.4.2.10

Molecular weight: Translated: 48781; Mature: 48781

Theoretical pI: Translated: 4.39; Mature: 4.39

Prosite motif: PS00710 PGM_PMM; PS00018 EF_HAND_1

Important sites: ACT_SITE 104-104

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLKYFGTDGVRGIANETLTPELAFQLGRAGGYVLTKHAKDDEQPRVLVSRDTRISGQLL
CEEEEECCCCCCCCCCCCCCHHHHHHHCCCCCEEEEECCCCCCCCEEEEECCCCHHHHHH
KHALISGLLSVGIEVMDMGIVTTPGVAYLVRKQEADAGVMITASHNPVQDNGIKFFGSDG
HHHHHHHHHHHCHHHEECCEECCCCCEEEEEECCCCCCEEEEECCCCCCCCCEEEECCCC
YKLSDELEAEIEVLLDADKDNLPRPSSTGLGSVTDYPEGGLNYTAFLEQTIPDDLEGLHI
CEECHHHHCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCEEE
AIDAANGATSSYVSQIFADLNTEFDTMATNPDGLNINAGVGSTHPEGLAKFVVEKGADMG
EEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHCCCCCC
VAFDGDGDRCIAVDELGNIVDGDKIMYICGKFLSERGRLKDDTVVTTVMSNLGLYKALEA
EEECCCCCEEEEHHHHCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEECCC
NDMHSVKTQVGDRYVVEEMLKDGYNLGGEQSGHIVFLDHNTTGDGMLTAIQLMYVVKQTG
CCHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHH
KKLSELAADVTTYPQKLVNVRVQDKKLALENQAIKDIIEKVENEMNGEGRVLVRPSGTED
HHHHHHHHHHHHHHHHHHEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHH
LLRIMAEAPTKEAVGQYVDRIVAVVQSEVGVD
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKLKYFGTDGVRGIANETLTPELAFQLGRAGGYVLTKHAKDDEQPRVLVSRDTRISGQLL
CEEEEECCCCCCCCCCCCCCHHHHHHHCCCCCEEEEECCCCCCCCEEEEECCCCHHHHHH
KHALISGLLSVGIEVMDMGIVTTPGVAYLVRKQEADAGVMITASHNPVQDNGIKFFGSDG
HHHHHHHHHHHCHHHEECCEECCCCCEEEEEECCCCCCEEEEECCCCCCCCCEEEECCCC
YKLSDELEAEIEVLLDADKDNLPRPSSTGLGSVTDYPEGGLNYTAFLEQTIPDDLEGLHI
CEECHHHHCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCEEE
AIDAANGATSSYVSQIFADLNTEFDTMATNPDGLNINAGVGSTHPEGLAKFVVEKGADMG
EEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHCCCCCC
VAFDGDGDRCIAVDELGNIVDGDKIMYICGKFLSERGRLKDDTVVTTVMSNLGLYKALEA
EEECCCCCEEEEHHHHCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEECCC
NDMHSVKTQVGDRYVVEEMLKDGYNLGGEQSGHIVFLDHNTTGDGMLTAIQLMYVVKQTG
CCHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHH
KKLSELAADVTTYPQKLVNVRVQDKKLALENQAIKDIIEKVENEMNGEGRVLVRPSGTED
HHHHHHHHHHHHHHHHHHEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHH
LLRIMAEAPTKEAVGQYVDRIVAVVQSEVGVD
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA