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The map label for this gene is secA1

Identifier: 116492231

GI number: 116492231

Start: 478431

End: 480791

Strand: Direct

Name: secA1

Synonym: PEPE_0428

Alternate gene names: 116492231

Gene position: 478431-480791 (Clockwise)

Preceding gene: 116492230

Following gene: 116492232

Centisome position: 26.11

GC content: 39.86

Gene sequence:

>2361_bases
ATGGCAAACATTTTAAAAAAATGGGTGGAAAGTGATGCGCGTGAGTTAAAAAGACTCGGTAAAAAAGCAGATAAGATTGA
AGCCCTAAAAGAAGAAATGGAACAACTAAATGATGAAAAACTTAAGGCTAAAACTACAGAGTTTAAAGAGCGTCTACAAA
ATGGCGAAACTTTAGATGATATTTTAGTTGAAGCTTTTGCAGTCGCACGTGAAGCAGCTAAGCGAGTATTAGGCTTATTC
CCATTCCGCGTCCAATTAATTGGTGGAATGGTACTTCATGGTGGTAACATTGCTGAAATGAAAACTGGTGAAGGTAAGAC
TTTAACGGCCACATTACCCGTGTATCTGAATGCCTTAGGTGGTAAAGGGGTTCACGTTGTTACTGTTAATGAATATTTGG
CTGAACGTGACTCAAGTGAAATGGGTGAGCTTTATAAATGGCTTGGCCTAACAGTAGGGGTTAATTCTTCAGAAATGACT
CCCGACCAAAAACGTGAAGCTTACAATTGTGATATCACTTATTCAACGAACAGTGAAATCGGTTTTGATTACTTAAGAGA
TAACATGGTTGTGTATAAAGAGGATATGGTACAACGTCCTCTAAACTTCGCCTTGATTGATGAGGTTGATTCAATTTTAA
TTGATGAAGCCAGGACACCTCTGATTATTTCTGGTCAGACTGAACCAACTGTTACGCTATATGAACGTGCTGACCGTTAC
GTGAAGACTTTGGCTGATGGTGATTACACGATTGATTGGGAATCAAAATCCATCTCATTAACAGAAAATGGGATTCGTCG
TGCGGAAAACTTCTTTAAAACCGACAACCTCTACGATGTTGAAAATAGTGCGTTGAACCATCATATTGATCAAGCTCTTC
GAGCAAATTATATTATGACTAAAGACAAGGACTACGTGGTTTCAGATGGTGAAGTCTTAATCGTTGATTCTTTTACAGGT
CGTGTAATGGAAGGCCGTCGTTTTTCTGATGGACTGCACCAAGCGATTGAAGCTAAGGAACACGTTGAAATTCAAGATGG
GGCTAAAACTATGGCCAACATCACTTATCAAAACTTGTTTAGAATGTATCGTAAACTTTCAGGGATGACCGGTACAGCTC
GGACTGAAGCAGAAGAATTCCGTGAAATTTACAATATGGAAGTTACAACCATTCCAACCAACCGTCCGGTGGCTCGTGAT
GACCGTCCAGATTTACTTTATCCAACTTTGGAAAGTAAATTTAAGGCAGTGGTGAAGGAAATCCGTGATTTGCATATTAA
AGGTCAACCAGTTCTAGTTGGTACGGTTGCGGTTGAAACTTCAGAATACCTCTCACGCTTGCTTGATCGAGAAGGTATTC
CACATGTTGTTTTGAATGCTAAGAATCATGCCCGTGAAGCTGAAATTGTTACCAACGCCGGTCAAAAGGGTGCGGTAACA
ATTGCTACTAATATGGCTGGTCGTGGTACTGATATTAAATTAGGACCTGGCGTAGTTGAACTAGGTGGTTTAGCTGTAAT
TGGTACTGAACGACATGAATCACGACGGATCGATAATCAGCTTCGTGGTCGTTCGGGACGTCAAGGTGATGTCGGAATGT
CCCAATTCTATCTTTCACTAGAAGATGACTTGATGATTCGTTTTGGTTCAGAACGAATCAAAGATTTGCTTTCTAGGATG
AAAATTGCGGATGAAGATGCAGTTATTCGAAGTGGTTTAATTAGCCGTCAAGTTGAATCTGCTCAAAAACGAGTTGAAGG
TAATAACTACGATGCTCGTAAGAACGTTCTTCAATACGATGATGTTATGCGTGCGCAACGTGAAGTGATTTACGCTGAAC
GTCAACAAGTGATCATGGAAGAAACTAGTCTAAAAGATGTGCTAATGCCGATGGTTGATCGAACGATTGACCGCGTGGTT
GATGCCCATACCCAAAAAACTCAAAAGAACTTTGATTTAGAAACCATTGTAGAATTTGCACGGACTGCCTTGGTTTCAGA
TAAAGACATTCATCAAGCTGATGTGGAAGGGATGTCTGCTAAAGAAATTAAGGACTACTTGAAACAACTAGCTGATCAAA
TGTACATTGAAAAAGAAAAAGCTTTGTACGACCCAGCTCAAATTCTAGAATTTGAAAAAGTTGTGATTCTCCGAGTGGTT
GACCAACACTGGACCGATCATATTGATGCCATGGACCAGTTACGTCAATCGGTTGGACTTCGAGGCTATGGACAGTTAAA
TCCATTAGTTGAATATCAACAAGAAGGTTACCGAATGTTCAACGAAATGATTACAGATATCGAATATGAAACTACTCGAT
TATTTATGAAATCTGAAATTCGTCAAAATCTTCAACGGTAG

Upstream 100 bases:

>100_bases
TTTAAATATATTTAAGATTAGTTTGATTGTAATAATAAAAATGATAAACTTAAACAGGTTATCGTTTTTACGATTAAGTT
AGTACGGAAGGAAATAGTAC

Downstream 100 bases:

>100_bases
TTGATTTATAATATAAAACTGGGAAGGTAATTTGACCGTTCCCAGTTTTTTAATGTGAAATGAAAAAAGGAGCTAACTTA
TATGGAGCTAGTTGAAGCAA

Product: protein translocase subunit secA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 786; Mature: 785

Protein sequence:

>786_residues
MANILKKWVESDARELKRLGKKADKIEALKEEMEQLNDEKLKAKTTEFKERLQNGETLDDILVEAFAVAREAAKRVLGLF
PFRVQLIGGMVLHGGNIAEMKTGEGKTLTATLPVYLNALGGKGVHVVTVNEYLAERDSSEMGELYKWLGLTVGVNSSEMT
PDQKREAYNCDITYSTNSEIGFDYLRDNMVVYKEDMVQRPLNFALIDEVDSILIDEARTPLIISGQTEPTVTLYERADRY
VKTLADGDYTIDWESKSISLTENGIRRAENFFKTDNLYDVENSALNHHIDQALRANYIMTKDKDYVVSDGEVLIVDSFTG
RVMEGRRFSDGLHQAIEAKEHVEIQDGAKTMANITYQNLFRMYRKLSGMTGTARTEAEEFREIYNMEVTTIPTNRPVARD
DRPDLLYPTLESKFKAVVKEIRDLHIKGQPVLVGTVAVETSEYLSRLLDREGIPHVVLNAKNHAREAEIVTNAGQKGAVT
IATNMAGRGTDIKLGPGVVELGGLAVIGTERHESRRIDNQLRGRSGRQGDVGMSQFYLSLEDDLMIRFGSERIKDLLSRM
KIADEDAVIRSGLISRQVESAQKRVEGNNYDARKNVLQYDDVMRAQREVIYAERQQVIMEETSLKDVLMPMVDRTIDRVV
DAHTQKTQKNFDLETIVEFARTALVSDKDIHQADVEGMSAKEIKDYLKQLADQMYIEKEKALYDPAQILEFEKVVILRVV
DQHWTDHIDAMDQLRQSVGLRGYGQLNPLVEYQQEGYRMFNEMITDIEYETTRLFMKSEIRQNLQR

Sequences:

>Translated_786_residues
MANILKKWVESDARELKRLGKKADKIEALKEEMEQLNDEKLKAKTTEFKERLQNGETLDDILVEAFAVAREAAKRVLGLF
PFRVQLIGGMVLHGGNIAEMKTGEGKTLTATLPVYLNALGGKGVHVVTVNEYLAERDSSEMGELYKWLGLTVGVNSSEMT
PDQKREAYNCDITYSTNSEIGFDYLRDNMVVYKEDMVQRPLNFALIDEVDSILIDEARTPLIISGQTEPTVTLYERADRY
VKTLADGDYTIDWESKSISLTENGIRRAENFFKTDNLYDVENSALNHHIDQALRANYIMTKDKDYVVSDGEVLIVDSFTG
RVMEGRRFSDGLHQAIEAKEHVEIQDGAKTMANITYQNLFRMYRKLSGMTGTARTEAEEFREIYNMEVTTIPTNRPVARD
DRPDLLYPTLESKFKAVVKEIRDLHIKGQPVLVGTVAVETSEYLSRLLDREGIPHVVLNAKNHAREAEIVTNAGQKGAVT
IATNMAGRGTDIKLGPGVVELGGLAVIGTERHESRRIDNQLRGRSGRQGDVGMSQFYLSLEDDLMIRFGSERIKDLLSRM
KIADEDAVIRSGLISRQVESAQKRVEGNNYDARKNVLQYDDVMRAQREVIYAERQQVIMEETSLKDVLMPMVDRTIDRVV
DAHTQKTQKNFDLETIVEFARTALVSDKDIHQADVEGMSAKEIKDYLKQLADQMYIEKEKALYDPAQILEFEKVVILRVV
DQHWTDHIDAMDQLRQSVGLRGYGQLNPLVEYQQEGYRMFNEMITDIEYETTRLFMKSEIRQNLQR
>Mature_785_residues
ANILKKWVESDARELKRLGKKADKIEALKEEMEQLNDEKLKAKTTEFKERLQNGETLDDILVEAFAVAREAAKRVLGLFP
FRVQLIGGMVLHGGNIAEMKTGEGKTLTATLPVYLNALGGKGVHVVTVNEYLAERDSSEMGELYKWLGLTVGVNSSEMTP
DQKREAYNCDITYSTNSEIGFDYLRDNMVVYKEDMVQRPLNFALIDEVDSILIDEARTPLIISGQTEPTVTLYERADRYV
KTLADGDYTIDWESKSISLTENGIRRAENFFKTDNLYDVENSALNHHIDQALRANYIMTKDKDYVVSDGEVLIVDSFTGR
VMEGRRFSDGLHQAIEAKEHVEIQDGAKTMANITYQNLFRMYRKLSGMTGTARTEAEEFREIYNMEVTTIPTNRPVARDD
RPDLLYPTLESKFKAVVKEIRDLHIKGQPVLVGTVAVETSEYLSRLLDREGIPHVVLNAKNHAREAEIVTNAGQKGAVTI
ATNMAGRGTDIKLGPGVVELGGLAVIGTERHESRRIDNQLRGRSGRQGDVGMSQFYLSLEDDLMIRFGSERIKDLLSRMK
IADEDAVIRSGLISRQVESAQKRVEGNNYDARKNVLQYDDVMRAQREVIYAERQQVIMEETSLKDVLMPMVDRTIDRVVD
AHTQKTQKNFDLETIVEFARTALVSDKDIHQADVEGMSAKEIKDYLKQLADQMYIEKEKALYDPAQILEFEKVVILRVVD
QHWTDHIDAMDQLRQSVGLRGYGQLNPLVEYQQEGYRMFNEMITDIEYETTRLFMKSEIRQNLQR

Specific function: Part of the Sec protein translocase complex. Interacts with the secYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular mo

COG id: COG0653

COG function: function code U; Preprotein translocase subunit SecA (ATPase, RNA helicase)

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm (By similarity). Note=Distribution is 50-50 (By similarity)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secA family

Homologues:

Organism=Escherichia coli, GI1786287, Length=821, Percent_Identity=46.5286236297199, Blast_Score=712, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SECA1_PEDPA (Q03GZ8)

Other databases:

- EMBL:   CP000422
- RefSeq:   YP_803966.1
- ProteinModelPortal:   Q03GZ8
- SMR:   Q03GZ8
- STRING:   Q03GZ8
- GeneID:   4418394
- GenomeReviews:   CP000422_GR
- KEGG:   ppe:PEPE_0428
- NMPDR:   fig|278197.10.peg.398
- eggNOG:   COG0653
- HOGENOM:   HBG284200
- OMA:   GGMVLHD
- BioCyc:   PPEN278197:PEPE_0428-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01382
- InterPro:   IPR000185
- InterPro:   IPR020937
- InterPro:   IPR011115
- InterPro:   IPR014018
- InterPro:   IPR011130
- InterPro:   IPR011116
- Gene3D:   G3DSA:1.10.3060.10
- PRINTS:   PR00906
- SMART:   SM00957
- SMART:   SM00958
- TIGRFAMs:   TIGR00963

Pfam domain/function: PF07517 SecA_DEAD; PF01043 SecA_PP_bind; PF07516 SecA_SW; SSF81767 SecA_PP_bd; SSF81886 SecA_SW

EC number: NA

Molecular weight: Translated: 89512; Mature: 89381

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS01312 SECA; PS51196 SECA_MOTOR_DEAD; PS00687 ALDEHYDE_DEHYDR_GLU

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANILKKWVESDARELKRLGKKADKIEALKEEMEQLNDEKLKAKTTEFKERLQNGETLDD
CHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCHHH
ILVEAFAVAREAAKRVLGLFPFRVQLIGGMVLHGGNIAEMKTGEGKTLTATLPVYLNALG
HHHHHHHHHHHHHHHHHHHCHHHHHHHCCEEEECCCEEEEECCCCCEEEEEHHHHHHCCC
GKGVHVVTVNEYLAERDSSEMGELYKWLGLTVGVNSSEMTPDQKREAYNCDITYSTNSEI
CCCEEEEEHHHHHHHCCCHHHHHHHHHHHHEECCCCCCCCCHHHHCCCCCEEEECCCCCC
GFDYLRDNMVVYKEDMVQRPLNFALIDEVDSILIDEARTPLIISGQTEPTVTLYERADRY
CHHHHHCCEEEEEHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHH
VKTLADGDYTIDWESKSISLTENGIRRAENFFKTDNLYDVENSALNHHIDQALRANYIMT
HHHHCCCCEEEEECCCEEEECHHHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHCCEEEE
KDKDYVVSDGEVLIVDSFTGRVMEGRRFSDGLHQAIEAKEHVEIQDGAKTMANITYQNLF
CCCCEEEECCCEEEEECCCCCHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
RMYRKLSGMTGTARTEAEEFREIYNMEVTTIPTNRPVARDDRPDLLYPTLESKFKAVVKE
HHHHHHCCCCCCCHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHH
IRDLHIKGQPVLVGTVAVETSEYLSRLLDREGIPHVVLNAKNHAREAEIVTNAGQKGAVT
HHHCCCCCCCEEEEEEEECHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHCCCCCCEEE
IATNMAGRGTDIKLGPGVVELGGLAVIGTERHESRRIDNQLRGRSGRQGDVGMSQFYLSL
EEECCCCCCCCEEECCCEEEECCEEEEECCCHHHHHHHHHHCCCCCCCCCCCHHHEEEEC
EDDLMIRFGSERIKDLLSRMKIADEDAVIRSGLISRQVESAQKRVEGNNYDARKNVLQYD
CCCEEEEECHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
DVMRAQREVIYAERQQVIMEETSLKDVLMPMVDRTIDRVVDAHTQKTQKNFDLETIVEFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
RTALVSDKDIHQADVEGMSAKEIKDYLKQLADQMYIEKEKALYDPAQILEFEKVVILRVV
HHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
DQHWTDHIDAMDQLRQSVGLRGYGQLNPLVEYQQEGYRMFNEMITDIEYETTRLFMKSEI
HHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
RQNLQR
HHHHCC
>Mature Secondary Structure 
ANILKKWVESDARELKRLGKKADKIEALKEEMEQLNDEKLKAKTTEFKERLQNGETLDD
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCHHH
ILVEAFAVAREAAKRVLGLFPFRVQLIGGMVLHGGNIAEMKTGEGKTLTATLPVYLNALG
HHHHHHHHHHHHHHHHHHHCHHHHHHHCCEEEECCCEEEEECCCCCEEEEEHHHHHHCCC
GKGVHVVTVNEYLAERDSSEMGELYKWLGLTVGVNSSEMTPDQKREAYNCDITYSTNSEI
CCCEEEEEHHHHHHHCCCHHHHHHHHHHHHEECCCCCCCCCHHHHCCCCCEEEECCCCCC
GFDYLRDNMVVYKEDMVQRPLNFALIDEVDSILIDEARTPLIISGQTEPTVTLYERADRY
CHHHHHCCEEEEEHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHH
VKTLADGDYTIDWESKSISLTENGIRRAENFFKTDNLYDVENSALNHHIDQALRANYIMT
HHHHCCCCEEEEECCCEEEECHHHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHCCEEEE
KDKDYVVSDGEVLIVDSFTGRVMEGRRFSDGLHQAIEAKEHVEIQDGAKTMANITYQNLF
CCCCEEEECCCEEEEECCCCCHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
RMYRKLSGMTGTARTEAEEFREIYNMEVTTIPTNRPVARDDRPDLLYPTLESKFKAVVKE
HHHHHHCCCCCCCHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHH
IRDLHIKGQPVLVGTVAVETSEYLSRLLDREGIPHVVLNAKNHAREAEIVTNAGQKGAVT
HHHCCCCCCCEEEEEEEECHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHCCCCCCEEE
IATNMAGRGTDIKLGPGVVELGGLAVIGTERHESRRIDNQLRGRSGRQGDVGMSQFYLSL
EEECCCCCCCCEEECCCEEEECCEEEEECCCHHHHHHHHHHCCCCCCCCCCCHHHEEEEC
EDDLMIRFGSERIKDLLSRMKIADEDAVIRSGLISRQVESAQKRVEGNNYDARKNVLQYD
CCCEEEEECHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
DVMRAQREVIYAERQQVIMEETSLKDVLMPMVDRTIDRVVDAHTQKTQKNFDLETIVEFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
RTALVSDKDIHQADVEGMSAKEIKDYLKQLADQMYIEKEKALYDPAQILEFEKVVILRVV
HHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
DQHWTDHIDAMDQLRQSVGLRGYGQLNPLVEYQQEGYRMFNEMITDIEYETTRLFMKSEI
HHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
RQNLQR
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA