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The map label for this gene is groS

Identifier: 116492223

GI number: 116492223

Start: 469476

End: 469760

Strand: Direct

Name: groS

Synonym: PEPE_0420

Alternate gene names: 116492223

Gene position: 469476-469760 (Clockwise)

Preceding gene: 116492220

Following gene: 116492224

Centisome position: 25.62

GC content: 37.19

Gene sequence:

>285_bases
GTGTTAAAACCTTTAGGAGATCGCGTTATTTTAGAAGCTAAAGATGAAGAAGAACAAACTGTCGGAGGCATCGTACTTGC
AAGCAATGCTAAAGAAAAGTCCCAAACTGGAAAGATTATCGCTGTCGGTAACGGTACAGTTTTAGACAATGGTCAAACAG
TACCAATGAACGTCAAAGTTGGCGATACAGTAGTATATGACAAATATGCTGGTACTGAAGTTTCATACGAAGATAAAAAA
TACTTAGTTGTCCATGAAAAGGACTTAGTTGCAGTAGTTGAATAA

Upstream 100 bases:

>100_bases
AATCTAAAAAAATCATGATATAGTTATCATTGTAGTTAGCACTTAGAGATGACGAGTGCTAAACAAATCTTATCAGTAAA
TTATATTTGGAGGGATTCAC

Downstream 100 bases:

>100_bases
TTAATTTTTAATTTAGGAGTGTTGATAATGGCTAAAGAAATTAAATTTTCAGAAGATGCACGTACAAAAATGCTTAAGGG
TGTAGATAAGTTAGCTGACA

Product: Co-chaperonin GroES (HSP10)

Products: NA

Alternate protein names: GroES protein; Protein Cpn10

Number of amino acids: Translated: 94; Mature: 94

Protein sequence:

>94_residues
MLKPLGDRVILEAKDEEEQTVGGIVLASNAKEKSQTGKIIAVGNGTVLDNGQTVPMNVKVGDTVVYDKYAGTEVSYEDKK
YLVVHEKDLVAVVE

Sequences:

>Translated_94_residues
MLKPLGDRVILEAKDEEEQTVGGIVLASNAKEKSQTGKIIAVGNGTVLDNGQTVPMNVKVGDTVVYDKYAGTEVSYEDKK
YLVVHEKDLVAVVE
>Mature_94_residues
MLKPLGDRVILEAKDEEEQTVGGIVLASNAKEKSQTGKIIAVGNGTVLDNGQTVPMNVKVGDTVVYDKYAGTEVSYEDKK
YLVVHEKDLVAVVE

Specific function: Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter

COG id: COG0234

COG function: function code O; Co-chaperonin GroES (HSP10)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GroES chaperonin family

Homologues:

Organism=Escherichia coli, GI1790585, Length=94, Percent_Identity=42.5531914893617, Blast_Score=82, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17555568, Length=93, Percent_Identity=37.6344086021505, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: 980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5720 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 1274 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): CH10_PEDPA (Q03H06)

Other databases:

- EMBL:   CP000422
- RefSeq:   YP_803958.1
- ProteinModelPortal:   Q03H06
- SMR:   Q03H06
- STRING:   Q03H06
- GeneID:   4418386
- GenomeReviews:   CP000422_GR
- KEGG:   ppe:PEPE_0420
- NMPDR:   fig|278197.10.peg.390
- eggNOG:   COG0234
- HOGENOM:   HBG703377
- OMA:   RVIYARY
- PhylomeDB:   Q03H06
- BioCyc:   PPEN278197:PEPE_0420-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00580
- InterPro:   IPR020818
- InterPro:   IPR018369
- InterPro:   IPR011032
- Gene3D:   G3DSA:2.30.33.40
- PANTHER:   PTHR10772
- PRINTS:   PR00297
- SMART:   SM00883

Pfam domain/function: PF00166 Cpn10; SSF50129 GroES_like

EC number: NA

Molecular weight: Translated: 10150; Mature: 10150

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: PS00681 CHAPERONINS_CPN10

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKPLGDRVILEAKDEEEQTVGGIVLASNAKEKSQTGKIIAVGNGTVLDNGQTVPMNVKV
CCCCCCCEEEEEECCCCCCCCCEEEEECCCCCCCCCCCEEEECCCEEEECCCEEEEEEEE
GDTVVYDKYAGTEVSYEDKKYLVVHEKDLVAVVE
CCEEEEECCCCCEECCCCCEEEEEECCCEEEEEC
>Mature Secondary Structure
MLKPLGDRVILEAKDEEEQTVGGIVLASNAKEKSQTGKIIAVGNGTVLDNGQTVPMNVKV
CCCCCCCEEEEEECCCCCCCCCEEEEECCCCCCCCCCCEEEECCCEEEECCCEEEEEEEE
GDTVVYDKYAGTEVSYEDKKYLVVHEKDLVAVVE
CCEEEEECCCCCEECCCCCEEEEEECCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA