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The map label for this gene is ackA [H]

Identifier: 116492139

GI number: 116492139

Start: 384056

End: 385255

Strand: Direct

Name: ackA [H]

Synonym: PEPE_0336

Alternate gene names: 116492139

Gene position: 384056-385255 (Clockwise)

Preceding gene: 116492138

Following gene: 116492140

Centisome position: 20.96

GC content: 36.42

Gene sequence:

>1200_bases
TTGGAAAAGACAATTGCAATCAATGCGGGAAGCTCAACCCTTAAGTTTAAATTATTTGAAATGCCGGAAGAAAAGGTTAT
TTCATCAGGAACTGTCGATCGGATCGGTATTCCAGGATCAAACTTCACGATTAAGACCACTGATGGTAAAAAAGTTGAAA
TTGACCAACCAATTAAAAATCATGAAGAAGCAGTTAATTTACTCTTAAAAGAGCTATTAAAATTAGATATTATTAAAGAT
TACAGTGAAATTACCGGTGTAGGACACCGAGTAGTTGCGGGTGGAGAAATTTTCCAAGATTCTGCTTTAATTGATGACAA
AGTCTTAAAGCAAATCGAAGACTTAAAAGAATATGCGCCTTTGCATAATCCAGCTAACGCTACAGGAATCCGTGCTTTCA
AGAAGGTTTTACCAGATATCACTAGTGTGGCAGTTTTTGATACATCTTTCCATGAAACGTTACCTGAAAAAAATTATCTT
TACAGTATTCCTTATGAATACTATGAAAAATATGGGGCTCGTAAATACGGTGCTCATGGTACTAGTCATCAATATGTAGC
AGGTCGTGCGGCTAAGATGATGGGCAAGCCATTAGAAGAACTAAAAATAATCACCTTACATTTAGGGGCTGGTAGTTCAA
TTACAGCTATCAAGGATGGAAAATCATTTGATACATCAATGGGCTTTACACCTCTAGCAGGGATTACTATGGCAACCCGT
TCTGGTGATATTGATGCCTCTTTAGTAGTTTACTTAATGCAAAAACTTAATATTACTAATCCGGAAGACATCTTAACTAT
TTTGAATAAGAAGTCTGGTTTGCTAGGACTATCAGGAATGTCACCTGATTTGCGTGATATAATTGATGCCGCTGAAAAAG
GTGAACATCGTGCACAAATGGCCATCGATATTTTTGTTAATAATATTGTGAAATACATTGGTTCCTATGCAACTGAAATG
GGTGGTTTAGATGGAATTGTATTTACAGCAGGAATTGGTGAAAATAGTGTTCCAATGCGTGAAAAAATTACTTCTAAATT
AGGAATTTTCAATGTTAAACTTGACCAAGCGCTTAATGAAAAACGTGGAGAACGTTTCATTAGTGCGGAAGACTCGGCTG
TCCAAGTCATGGTAATTCCAACTGATGAAGAATTGGCGATTGCTCGCGATGTTGAAAAGTTTAAAAAAATGGGGGACTAA

Upstream 100 bases:

>100_bases
AAATAATAATATTTAAAAATTCTAACGATGAATTTTACAAGCTTACAAACAGATAATACGTTACAATAAGCTATTATTAT
GAGAGAAGGAGCTATTTAAG

Downstream 100 bases:

>100_bases
CTCATGGATTTATTTGAAGGTTTGAAGTCAAAAATTAAGGGCCAAAATAGAACAGTTGTATTTCCCGAAGGTGAAGATGT
TCGAGTTTTAGCTGCCGCTA

Product: acetate kinase

Products: NA

Alternate protein names: Acetokinase [H]

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MEKTIAINAGSSTLKFKLFEMPEEKVISSGTVDRIGIPGSNFTIKTTDGKKVEIDQPIKNHEEAVNLLLKELLKLDIIKD
YSEITGVGHRVVAGGEIFQDSALIDDKVLKQIEDLKEYAPLHNPANATGIRAFKKVLPDITSVAVFDTSFHETLPEKNYL
YSIPYEYYEKYGARKYGAHGTSHQYVAGRAAKMMGKPLEELKIITLHLGAGSSITAIKDGKSFDTSMGFTPLAGITMATR
SGDIDASLVVYLMQKLNITNPEDILTILNKKSGLLGLSGMSPDLRDIIDAAEKGEHRAQMAIDIFVNNIVKYIGSYATEM
GGLDGIVFTAGIGENSVPMREKITSKLGIFNVKLDQALNEKRGERFISAEDSAVQVMVIPTDEELAIARDVEKFKKMGD

Sequences:

>Translated_399_residues
MEKTIAINAGSSTLKFKLFEMPEEKVISSGTVDRIGIPGSNFTIKTTDGKKVEIDQPIKNHEEAVNLLLKELLKLDIIKD
YSEITGVGHRVVAGGEIFQDSALIDDKVLKQIEDLKEYAPLHNPANATGIRAFKKVLPDITSVAVFDTSFHETLPEKNYL
YSIPYEYYEKYGARKYGAHGTSHQYVAGRAAKMMGKPLEELKIITLHLGAGSSITAIKDGKSFDTSMGFTPLAGITMATR
SGDIDASLVVYLMQKLNITNPEDILTILNKKSGLLGLSGMSPDLRDIIDAAEKGEHRAQMAIDIFVNNIVKYIGSYATEM
GGLDGIVFTAGIGENSVPMREKITSKLGIFNVKLDQALNEKRGERFISAEDSAVQVMVIPTDEELAIARDVEKFKKMGD
>Mature_399_residues
MEKTIAINAGSSTLKFKLFEMPEEKVISSGTVDRIGIPGSNFTIKTTDGKKVEIDQPIKNHEEAVNLLLKELLKLDIIKD
YSEITGVGHRVVAGGEIFQDSALIDDKVLKQIEDLKEYAPLHNPANATGIRAFKKVLPDITSVAVFDTSFHETLPEKNYL
YSIPYEYYEKYGARKYGAHGTSHQYVAGRAAKMMGKPLEELKIITLHLGAGSSITAIKDGKSFDTSMGFTPLAGITMATR
SGDIDASLVVYLMQKLNITNPEDILTILNKKSGLLGLSGMSPDLRDIIDAAEKGEHRAQMAIDIFVNNIVKYIGSYATEM
GGLDGIVFTAGIGENSVPMREKITSKLGIFNVKLDQALNEKRGERFISAEDSAVQVMVIPTDEELAIARDVEKFKKMGD

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG0282

COG function: function code C; Acetate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetokinase family [H]

Homologues:

Organism=Escherichia coli, GI145693184, Length=398, Percent_Identity=40.2010050251256, Blast_Score=308, Evalue=3e-85,
Organism=Escherichia coli, GI1788633, Length=396, Percent_Identity=41.9191919191919, Blast_Score=303, Evalue=2e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000890
- InterPro:   IPR004372 [H]

Pfam domain/function: PF00871 Acetate_kinase [H]

EC number: =2.7.2.1 [H]

Molecular weight: Translated: 43741; Mature: 43741

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: PS01075 ACETATE_KINASE_1 ; PS01076 ACETATE_KINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKTIAINAGSSTLKFKLFEMPEEKVISSGTVDRIGIPGSNFTIKTTDGKKVEIDQPIKN
CCCEEEEECCCCEEEEEEECCCHHHHHCCCCCCEECCCCCCEEEEECCCCEEEECCCCCH
HEEAVNLLLKELLKLDIIKDYSEITGVGHRVVAGGEIFQDSALIDDKVLKQIEDLKEYAP
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHCCCHHHHHHHHHHHHHHHHHCC
LHNPANATGIRAFKKVLPDITSVAVFDTSFHETLPEKNYLYSIPYEYYEKYGARKYGAHG
CCCCCCCHHHHHHHHHCCCHHHEEEECCHHHHHCCCCCCEEECCHHHHHHHCCCCCCCCC
TSHQYVAGRAAKMMGKPLEELKIITLHLGAGSSITAIKDGKSFDTSMGFTPLAGITMATR
CCCCHHHHHHHHHHCCCHHHEEEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCEEEEEC
SGDIDASLVVYLMQKLNITNPEDILTILNKKSGLLGLSGMSPDLRDIIDAAEKGEHRAQM
CCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHCCCHHHHH
AIDIFVNNIVKYIGSYATEMGGLDGIVFTAGIGENSVPMREKITSKLGIFNVKLDQALNE
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHCEEEEEHHHHHHH
KRGERFISAEDSAVQVMVIPTDEELAIARDVEKFKKMGD
HHCCEEECCCCCEEEEEEECCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEKTIAINAGSSTLKFKLFEMPEEKVISSGTVDRIGIPGSNFTIKTTDGKKVEIDQPIKN
CCCEEEEECCCCEEEEEEECCCHHHHHCCCCCCEECCCCCCEEEEECCCCEEEECCCCCH
HEEAVNLLLKELLKLDIIKDYSEITGVGHRVVAGGEIFQDSALIDDKVLKQIEDLKEYAP
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHCCCHHHHHHHHHHHHHHHHHCC
LHNPANATGIRAFKKVLPDITSVAVFDTSFHETLPEKNYLYSIPYEYYEKYGARKYGAHG
CCCCCCCHHHHHHHHHCCCHHHEEEECCHHHHHCCCCCCEEECCHHHHHHHCCCCCCCCC
TSHQYVAGRAAKMMGKPLEELKIITLHLGAGSSITAIKDGKSFDTSMGFTPLAGITMATR
CCCCHHHHHHHHHHCCCHHHEEEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCEEEEEC
SGDIDASLVVYLMQKLNITNPEDILTILNKKSGLLGLSGMSPDLRDIIDAAEKGEHRAQM
CCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHCCCHHHHH
AIDIFVNNIVKYIGSYATEMGGLDGIVFTAGIGENSVPMREKITSKLGIFNVKLDQALNE
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHCEEEEEHHHHHHH
KRGERFISAEDSAVQVMVIPTDEELAIARDVEKFKKMGD
HHCCEEECCCCCEEEEEEECCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12566566 [H]