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The map label for this gene is bglA [H]

Identifier: 116492087

GI number: 116492087

Start: 327507

End: 328952

Strand: Direct

Name: bglA [H]

Synonym: PEPE_0283

Alternate gene names: 116492087

Gene position: 327507-328952 (Clockwise)

Preceding gene: 116492086

Following gene: 116492088

Centisome position: 17.87

GC content: 38.17

Gene sequence:

>1446_bases
ATGACTGAAAAGCATTATAAGATGCCGGAAAATTTCTTGTGGGGCGGTGCAGTAGCCGCTCATCAATTTGAAGGCGGATG
GCAAGAAGGCGGTAAGGGAGTTAGCATTGCAGACGTGATGACCGCTGGAAACAAAGATACTGCTCGAAAAGTAACGGACG
GTATTAAAGATGGAGAAGTTTACCCAAATCACTGGGGGATTGATTTTTATCATCGTTATCCTGAAGATATTAAACTTTTT
AACGAAATGGGTTTCAAATGCTTCCGTACCTCGATTGCATGGACTAGAATTTTTCCTAATGGAGATGAAACCGAACCTAA
CGAAGCTGGTTTAAAGTTCTATGATGATATGTTTGATGAACTGTTAAAATACAATATTCAACCCATCATTACTTTGTCAC
ACTTCGAAATGCCATATCATTTAGTAAAAGAATATGGTGGTTGGACTAATCGTAAATTGATTGACTTTTTCGTACGTTTT
GCCGAAACAGTGATGAAACGCTATAAGGGAAAAGTTAAGTACTGGATGACCTTCAACGAGATTAATAATCAAACTGATTG
GAGTAATCCTCATCATTTACTTCAAGATTCAGCCATTAAGGTTAAAGCTGGAACACCAGGAATGGAAGAAATGATGTATC
AAGCCGCTCATAACGAAATGGTTGCAAGTGCTAAAGTAGTTGAACTAGGCCATCAAATTGATTCGGAATATCAAATTGGT
GCAATGATTGCAATGTGTCCAATTTATCCACTAACTGCTAAGCCAGAAGACATCATGATGGCTGAACGTGCTATGCAAAC
GCGTTACTACTTTGGAGACGTTCAAGCTAATGGTGAATACCCTAATTGGCTTCCTAAATATTGGGAACGCCAAAACATCC
ATGTCGAAATTAGTGATTATGACCGAGAAATTTTGAAAAAGGGTGCAGTTGATTATATTGGATTTAGTTACTATATGTCA
TTTACAACTAAATCTACGGATGAAAATACCGACTATGCCTATAAAGAAGCACGTGATTTAGTCGACAATCCTTATGTTCA
AAAATCAGATTGGGGCTGGCAGATTGATCCTGTTGGTCTACGTTATTCGATGAATTGGATGCAAGATCGTTGGCACAAAC
CTCAATTTATTGTGGAAAATGGTTTTGGAGCATACGACCAAAAAGAAGCCGATGGTGCTGTCCATGATGATTATCGCATC
AAGTATTTCCACGATCATATTTTAGAGATGGAAAAAGCAGTTGCCTTAGATGGGGTCAACTTAATTGGTTATACTCCATG
GGGATGCATCGATTTAATTTCAGCAAGTACTGGAGAAATGGCTAAACGTTATGGATTTATCTATGTTGATCAAGATGACC
AGGGTAATGGTAGTCTAGAACGTTCGAAGAAGGATTCATTTGATTGGTACAAACAAGTAATTGCATCTAATGGTGAAGAT
TTATAG

Upstream 100 bases:

>100_bases
ACAAGACCACATCATGAATGCCATTACTTTTAGAGATTTAGCTGGAGAAATTGTTGATTTATATAAAAAAATGGCCGAAA
AATAAAGTGAGGTTTTAATC

Downstream 100 bases:

>100_bases
TAAGTTGTTTAAGAATAATCAAGTTTTAAAGAGGTGATGTTGATGTTTAGTTATGAAAAAGTTCAAACGTTGAATCAATT
GGAATTGTTTGTGTATAAAT

Product: Beta-glucosidase/6-phospho-beta- glucosidase/beta-galactosidase

Products: NA

Alternate protein names: 6-phospho-beta-glucosidase [H]

Number of amino acids: Translated: 481; Mature: 480

Protein sequence:

>481_residues
MTEKHYKMPENFLWGGAVAAHQFEGGWQEGGKGVSIADVMTAGNKDTARKVTDGIKDGEVYPNHWGIDFYHRYPEDIKLF
NEMGFKCFRTSIAWTRIFPNGDETEPNEAGLKFYDDMFDELLKYNIQPIITLSHFEMPYHLVKEYGGWTNRKLIDFFVRF
AETVMKRYKGKVKYWMTFNEINNQTDWSNPHHLLQDSAIKVKAGTPGMEEMMYQAAHNEMVASAKVVELGHQIDSEYQIG
AMIAMCPIYPLTAKPEDIMMAERAMQTRYYFGDVQANGEYPNWLPKYWERQNIHVEISDYDREILKKGAVDYIGFSYYMS
FTTKSTDENTDYAYKEARDLVDNPYVQKSDWGWQIDPVGLRYSMNWMQDRWHKPQFIVENGFGAYDQKEADGAVHDDYRI
KYFHDHILEMEKAVALDGVNLIGYTPWGCIDLISASTGEMAKRYGFIYVDQDDQGNGSLERSKKDSFDWYKQVIASNGED
L

Sequences:

>Translated_481_residues
MTEKHYKMPENFLWGGAVAAHQFEGGWQEGGKGVSIADVMTAGNKDTARKVTDGIKDGEVYPNHWGIDFYHRYPEDIKLF
NEMGFKCFRTSIAWTRIFPNGDETEPNEAGLKFYDDMFDELLKYNIQPIITLSHFEMPYHLVKEYGGWTNRKLIDFFVRF
AETVMKRYKGKVKYWMTFNEINNQTDWSNPHHLLQDSAIKVKAGTPGMEEMMYQAAHNEMVASAKVVELGHQIDSEYQIG
AMIAMCPIYPLTAKPEDIMMAERAMQTRYYFGDVQANGEYPNWLPKYWERQNIHVEISDYDREILKKGAVDYIGFSYYMS
FTTKSTDENTDYAYKEARDLVDNPYVQKSDWGWQIDPVGLRYSMNWMQDRWHKPQFIVENGFGAYDQKEADGAVHDDYRI
KYFHDHILEMEKAVALDGVNLIGYTPWGCIDLISASTGEMAKRYGFIYVDQDDQGNGSLERSKKDSFDWYKQVIASNGED
L
>Mature_480_residues
TEKHYKMPENFLWGGAVAAHQFEGGWQEGGKGVSIADVMTAGNKDTARKVTDGIKDGEVYPNHWGIDFYHRYPEDIKLFN
EMGFKCFRTSIAWTRIFPNGDETEPNEAGLKFYDDMFDELLKYNIQPIITLSHFEMPYHLVKEYGGWTNRKLIDFFVRFA
ETVMKRYKGKVKYWMTFNEINNQTDWSNPHHLLQDSAIKVKAGTPGMEEMMYQAAHNEMVASAKVVELGHQIDSEYQIGA
MIAMCPIYPLTAKPEDIMMAERAMQTRYYFGDVQANGEYPNWLPKYWERQNIHVEISDYDREILKKGAVDYIGFSYYMSF
TTKSTDENTDYAYKEARDLVDNPYVQKSDWGWQIDPVGLRYSMNWMQDRWHKPQFIVENGFGAYDQKEADGAVHDDYRIK
YFHDHILEMEKAVALDGVNLIGYTPWGCIDLISASTGEMAKRYGFIYVDQDDQGNGSLERSKKDSFDWYKQVIASNGEDL

Specific function: Catalyzes the hydrolysis of aryl-phospho-beta-D- glucosides such as 4-methylumbelliferyl-phospho-beta-D- glucopyranoside (MUG-P), phosphoarbutin and phosphosalicin. Plays a major role in the utilization of arbutin or salicin as the sole carbon source. Bgl

COG id: COG2723

COG function: function code G; Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 1 family [H]

Homologues:

Organism=Homo sapiens, GI110681710, Length=499, Percent_Identity=29.6593186372746, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI32481206, Length=495, Percent_Identity=27.6767676767677, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI24497614, Length=487, Percent_Identity=28.5420944558522, Blast_Score=168, Evalue=8e-42,
Organism=Homo sapiens, GI13273313, Length=491, Percent_Identity=26.8839103869654, Blast_Score=160, Evalue=3e-39,
Organism=Homo sapiens, GI28376633, Length=488, Percent_Identity=25.8196721311475, Blast_Score=143, Evalue=3e-34,
Organism=Escherichia coli, GI2367174, Length=481, Percent_Identity=58.004158004158, Blast_Score=595, Evalue=1e-171,
Organism=Escherichia coli, GI1789070, Length=478, Percent_Identity=48.326359832636, Blast_Score=478, Evalue=1e-136,
Organism=Escherichia coli, GI2367270, Length=476, Percent_Identity=49.7899159663866, Blast_Score=476, Evalue=1e-135,
Organism=Caenorhabditis elegans, GI17552856, Length=495, Percent_Identity=28.2828282828283, Blast_Score=172, Evalue=5e-43,
Organism=Caenorhabditis elegans, GI17539390, Length=503, Percent_Identity=27.2365805168986, Blast_Score=160, Evalue=2e-39,
Organism=Drosophila melanogaster, GI21356577, Length=505, Percent_Identity=28.5148514851485, Blast_Score=166, Evalue=3e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001360
- InterPro:   IPR018120
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00232 Glyco_hydro_1 [H]

EC number: =3.2.1.86 [H]

Molecular weight: Translated: 55934; Mature: 55803

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS00653 GLYCOSYL_HYDROL_F1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEKHYKMPENFLWGGAVAAHQFEGGWQEGGKGVSIADVMTAGNKDTARKVTDGIKDGEV
CCCCCCCCCCCCCCCCHHHHHHCCCCHHCCCCCCCHHHHHCCCCCHHHHHHHCCCCCCCC
YPNHWGIDFYHRYPEDIKLFNEMGFKCFRTSIAWTRIFPNGDETEPNEAGLKFYDDMFDE
CCCCCCCHHHHCCCHHHHHHHHHCHHHHHHHHEEEEECCCCCCCCCCCCCHHHHHHHHHH
LLKYNIQPIITLSHFEMPYHLVKEYGGWTNRKLIDFFVRFAETVMKRYKGKVKYWMTFNE
HHHCCCCEEEEEECCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEHH
INNQTDWSNPHHLLQDSAIKVKAGTPGMEEMMYQAAHNEMVASAKVVELGHQIDSEYQIG
CCCCCCCCCCHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
AMIAMCPIYPLTAKPEDIMMAERAMQTRYYFGDVQANGEYPNWLPKYWERQNIHVEISDY
HEEEECCCCCCCCCCHHHHHHHHHHHHHEEEEEEEECCCCCCCCHHHHCCCCEEEEECHH
DREILKKGAVDYIGFSYYMSFTTKSTDENTDYAYKEARDLVDNPYVQKSDWGWQIDPVGL
HHHHHHCCCHHHEEHEEEEEEEECCCCCCCCHHHHHHHHHHCCCCEECCCCCEEECCCCE
RYSMNWMQDRWHKPQFIVENGFGAYDQKEADGAVHDDYRIKYFHDHILEMEKAVALDGVN
EEECHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCE
LIGYTPWGCIDLISASTGEMAKRYGFIYVDQDDQGNGSLERSKKDSFDWYKQVIASNGED
EEEECCCHHHHHHCCCHHHHHHHCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCC
L
C
>Mature Secondary Structure 
TEKHYKMPENFLWGGAVAAHQFEGGWQEGGKGVSIADVMTAGNKDTARKVTDGIKDGEV
CCCCCCCCCCCCCCCHHHHHHCCCCHHCCCCCCCHHHHHCCCCCHHHHHHHCCCCCCCC
YPNHWGIDFYHRYPEDIKLFNEMGFKCFRTSIAWTRIFPNGDETEPNEAGLKFYDDMFDE
CCCCCCCHHHHCCCHHHHHHHHHCHHHHHHHHEEEEECCCCCCCCCCCCCHHHHHHHHHH
LLKYNIQPIITLSHFEMPYHLVKEYGGWTNRKLIDFFVRFAETVMKRYKGKVKYWMTFNE
HHHCCCCEEEEEECCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEHH
INNQTDWSNPHHLLQDSAIKVKAGTPGMEEMMYQAAHNEMVASAKVVELGHQIDSEYQIG
CCCCCCCCCCHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
AMIAMCPIYPLTAKPEDIMMAERAMQTRYYFGDVQANGEYPNWLPKYWERQNIHVEISDY
HEEEECCCCCCCCCCHHHHHHHHHHHHHEEEEEEEECCCCCCCCHHHHCCCCEEEEECHH
DREILKKGAVDYIGFSYYMSFTTKSTDENTDYAYKEARDLVDNPYVQKSDWGWQIDPVGL
HHHHHHCCCHHHEEHEEEEEEEECCCCCCCCHHHHHHHHHHCCCCEECCCCCEEECCCCE
RYSMNWMQDRWHKPQFIVENGFGAYDQKEADGAVHDDYRIKYFHDHILEMEKAVALDGVN
EEECHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCE
LIGYTPWGCIDLISASTGEMAKRYGFIYVDQDDQGNGSLERSKKDSFDWYKQVIASNGED
EEEECCCHHHHHHCCCHHHHHHHCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCC
L
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8125345; 9384377 [H]