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The map label for this gene is hexR [C]

Identifier: 116492088

GI number: 116492088

Start: 328995

End: 329750

Strand: Direct

Name: hexR [C]

Synonym: PEPE_0284

Alternate gene names: 116492088

Gene position: 328995-329750 (Clockwise)

Preceding gene: 116492087

Following gene: 116492089

Centisome position: 17.95

GC content: 37.17

Gene sequence:

>756_bases
ATGTTTAGTTATGAAAAAGTTCAAACGTTGAATCAATTGGAATTGTTTGTGTATAAATACGTAACTAGTCATCTAGAAGA
GTGTAAAACCATGACTATTCGAGATTTATCCACGCAGAGTCACGTATCTTCTACGACCATTTTAAGATTTTTGAAGAAAA
TGGGATTTGAGGGTTTTTCTGATTTTAAGTATGTTTTACGCCATCGAAATGATCGAACTCCTGCTAGTGAATTGAGCCAA
GACTTAGGTCCAATAGGTCAATTTCTAAAACAGACTGCTACAACAGAATATACCGAAAAAATGGAAGAAGTTGCTCGCGT
GGTTGCACAATCCAACACCCGTTTGTTCTTTGGAATGGGATCAAGTGGTAGTATGGCACAATATGGAGCACGAATTTTAT
CGAATTATGGGATGCTCACATTGGCCATTACCGATCCTTTCCAACCTCAACCCATCTCGGAACGCGACTATTCTAAAACA
TTGATTATTTTACTATCAGTCTCTGGCGAAACTGAAGGTGTTTTAACGCAGGCCAATTATTATCGCCAAAATGGGGCAAA
AATTGTAGCAATTACTGCTAATAGTACTTCAACGTTGGCGCAGATTGCGGACTATAGTTTAACTTATGATATTCCCGAAA
ATAAAGTAGGATCGTTGAATTTTACATCGCAAATCCCAGTTGTCTACCTGCTAGAGCAACTTGGTGAAAAAACTAGTAAA
TTAGTTTATCATCCTGAAATCAGTCATGAAATTTAA

Upstream 100 bases:

>100_bases
GAAGGATTCATTTGATTGGTACAAACAAGTAATTGCATCTAATGGTGAAGATTTATAGTAAGTTGTTTAAGAATAATCAA
GTTTTAAAGAGGTGATGTTG

Downstream 100 bases:

>100_bases
ATTAATGAAACGATAATCGGTACTTGACGATTATTGTTTCATTTTTTTGTTCTAAAGGACCAGAGTTAAGTTGACAAAGC
AATGAAAGCGCTTAATAATT

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MFSYEKVQTLNQLELFVYKYVTSHLEECKTMTIRDLSTQSHVSSTTILRFLKKMGFEGFSDFKYVLRHRNDRTPASELSQ
DLGPIGQFLKQTATTEYTEKMEEVARVVAQSNTRLFFGMGSSGSMAQYGARILSNYGMLTLAITDPFQPQPISERDYSKT
LIILLSVSGETEGVLTQANYYRQNGAKIVAITANSTSTLAQIADYSLTYDIPENKVGSLNFTSQIPVVYLLEQLGEKTSK
LVYHPEISHEI

Sequences:

>Translated_251_residues
MFSYEKVQTLNQLELFVYKYVTSHLEECKTMTIRDLSTQSHVSSTTILRFLKKMGFEGFSDFKYVLRHRNDRTPASELSQ
DLGPIGQFLKQTATTEYTEKMEEVARVVAQSNTRLFFGMGSSGSMAQYGARILSNYGMLTLAITDPFQPQPISERDYSKT
LIILLSVSGETEGVLTQANYYRQNGAKIVAITANSTSTLAQIADYSLTYDIPENKVGSLNFTSQIPVVYLLEQLGEKTSK
LVYHPEISHEI
>Mature_251_residues
MFSYEKVQTLNQLELFVYKYVTSHLEECKTMTIRDLSTQSHVSSTTILRFLKKMGFEGFSDFKYVLRHRNDRTPASELSQ
DLGPIGQFLKQTATTEYTEKMEEVARVVAQSNTRLFFGMGSSGSMAQYGARILSNYGMLTLAITDPFQPQPISERDYSKT
LIILLSVSGETEGVLTQANYYRQNGAKIVAITANSTSTLAQIADYSLTYDIPENKVGSLNFTSQIPVVYLLEQLGEKTSK
LVYHPEISHEI

Specific function: Represses The Expression Of The Hex Regulon (Zwf, Eda, Glp And Gap) (By Similarity). [C]

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01418 HTH_6; PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 28280; Mature: 28280

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS51071 HTH_RPIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSYEKVQTLNQLELFVYKYVTSHLEECKTMTIRDLSTQSHVSSTTILRFLKKMGFEGFS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHH
DFKYVLRHRNDRTPASELSQDLGPIGQFLKQTATTEYTEKMEEVARVVAQSNTRLFFGMG
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEC
SSGSMAQYGARILSNYGMLTLAITDPFQPQPISERDYSKTLIILLSVSGETEGVLTQANY
CCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCEEEEEEEECCCCCCEEEHHHH
YRQNGAKIVAITANSTSTLAQIADYSLTYDIPENKVGSLNFTSQIPVVYLLEQLGEKTSK
HHCCCCEEEEEECCCHHHHHHHHCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHCCHHHC
LVYHPEISHEI
EEECCCCCCCC
>Mature Secondary Structure
MFSYEKVQTLNQLELFVYKYVTSHLEECKTMTIRDLSTQSHVSSTTILRFLKKMGFEGFS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHH
DFKYVLRHRNDRTPASELSQDLGPIGQFLKQTATTEYTEKMEEVARVVAQSNTRLFFGMG
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEC
SSGSMAQYGARILSNYGMLTLAITDPFQPQPISERDYSKTLIILLSVSGETEGVLTQANY
CCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCEEEEEEEECCCCCCEEEHHHH
YRQNGAKIVAITANSTSTLAQIADYSLTYDIPENKVGSLNFTSQIPVVYLLEQLGEKTSK
HHCCCCEEEEEECCCHHHHHHHHCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHCCHHHC
LVYHPEISHEI
EEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8177218; 11792842 [H]