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The map label for this gene is aroB [H]

Identifier: 116492061

GI number: 116492061

Start: 306083

End: 307012

Strand: Direct

Name: aroB [H]

Synonym: PEPE_0257

Alternate gene names: 116492061

Gene position: 306083-307012 (Clockwise)

Preceding gene: 116492060

Following gene: 116492062

Centisome position: 16.7

GC content: 39.68

Gene sequence:

>930_bases
ATGAAAAATTTGGTAATAGTAGATTTAGGATCAAACTCCGCTCGAATGGCAATTAATTCGATTGCTGATGATGGAACCTT
TCGAGAAATTAAGCGAGTTAAAGAAGATTCACGAATTTCAGAAGGAATGGGGCGCGAGCGTCTTTTACGTCCCCAAGCAA
TGAATCGTACCATTGCAGCCCTACGTCGATTTAAAGAAATTTATGAAGAATATCCTAATACAGAAGTTAGAGGGATTACA
ACAGCAGCTGTTAGAATGGCGCGAAATCAGAACGATTTTTTAAATCGCGTTAAGCAAGAAACTGGAATTAAATTACACGT
CTTGTCTGGCGACGATGAGGCCTATTACGATTATTTAGGTGTAATCAATTCCTTGGAAGTTAAGGATTGTTTGATACTTG
ATACTGGTGGTGCCAGCTGTGAGCTAATTGACGTCCATAATGGAAAAGCGCGAAATATGATCAGTATTCCGATTGGCGCT
GTGTCTTTATCGGAACGGTTCCGCTTAACGGACGTAGTTAGAGCAGATAATTTATTTGCCGCTGAAATTTTTGTGAATAA
GCAACTACGAGACGTTTGGTGGATTATGGATGCTTTCAATAAACCCATTGTTCTCTTAGGCGGAGCTAATCGGACACTGG
CCCGAATGAATCGTCGTCACCAAAAAATTTCTAGAATTAATAATATCCACGGCTATCGGCTCAAAACTGAATCGGTTAAC
CGAACCTTCAAATCGTTAATTACGCGGAATTTAGAAGCTCGTAAAAAAATGTCTGGGCTTGAAACTACGCGTGCAGATAT
TATCGTTGGTGGAATGTTACCATTGGTGATGTTATTACAAATGATTGACGCTGATCGAGTAATTTTTTCTGAAAGTGGCG
TTCGGGAAGGAATCATTTCGGAGTACATCAATTTTAGAAAAGAGGAATAG

Upstream 100 bases:

>100_bases
TTTGTTTTTATTTTAGTTGATAGGCGAGATGAGCTCCTTTTCTAATTTAGGTAATGGTAAAATAAAAAAGGAATATTTCA
ATTTAAATGAGGACACCAGG

Downstream 100 bases:

>100_bases
TTTTAATGATAGAAGGCTACCACAAATTAACGCGTCAACAGCAACTCGAGCAATTAGCGCAGGAAACTGACGTTGATTTG
TCTGAACTAACTGAATTAGC

Product: exopolyphosphatase

Products: NA

Alternate protein names: 3-dehydroquinate synthase; Unknown phosphatase [H]

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MKNLVIVDLGSNSARMAINSIADDGTFREIKRVKEDSRISEGMGRERLLRPQAMNRTIAALRRFKEIYEEYPNTEVRGIT
TAAVRMARNQNDFLNRVKQETGIKLHVLSGDDEAYYDYLGVINSLEVKDCLILDTGGASCELIDVHNGKARNMISIPIGA
VSLSERFRLTDVVRADNLFAAEIFVNKQLRDVWWIMDAFNKPIVLLGGANRTLARMNRRHQKISRINNIHGYRLKTESVN
RTFKSLITRNLEARKKMSGLETTRADIIVGGMLPLVMLLQMIDADRVIFSESGVREGIISEYINFRKEE

Sequences:

>Translated_309_residues
MKNLVIVDLGSNSARMAINSIADDGTFREIKRVKEDSRISEGMGRERLLRPQAMNRTIAALRRFKEIYEEYPNTEVRGIT
TAAVRMARNQNDFLNRVKQETGIKLHVLSGDDEAYYDYLGVINSLEVKDCLILDTGGASCELIDVHNGKARNMISIPIGA
VSLSERFRLTDVVRADNLFAAEIFVNKQLRDVWWIMDAFNKPIVLLGGANRTLARMNRRHQKISRINNIHGYRLKTESVN
RTFKSLITRNLEARKKMSGLETTRADIIVGGMLPLVMLLQMIDADRVIFSESGVREGIISEYINFRKEE
>Mature_309_residues
MKNLVIVDLGSNSARMAINSIADDGTFREIKRVKEDSRISEGMGRERLLRPQAMNRTIAALRRFKEIYEEYPNTEVRGIT
TAAVRMARNQNDFLNRVKQETGIKLHVLSGDDEAYYDYLGVINSLEVKDCLILDTGGASCELIDVHNGKARNMISIPIGA
VSLSERFRLTDVVRADNLFAAEIFVNKQLRDVWWIMDAFNKPIVLLGGANRTLARMNRRHQKISRINNIHGYRLKTESVN
RTFKSLITRNLEARKKMSGLETTRADIIVGGMLPLVMLLQMIDADRVIFSESGVREGIISEYINFRKEE

Specific function: Conversion Of Pppgpp To Ppgpp. Guanosine Pentaphosphate (Pppgpp) Is A Cytoplasmic Signaling Molecule Which Together With Ppgpp Controls The "Stringent Response", An Adaptive Process That Allows Bacteria To Respond To Amino Acid Starvation, Resulting In T

COG id: COG0248

COG function: function code FP; Exopolyphosphatase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the gppA/ppx family [H]

Homologues:

Organism=Escherichia coli, GI48994966, Length=307, Percent_Identity=26.0586319218241, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1788848, Length=301, Percent_Identity=24.5847176079734, Blast_Score=92, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6321185, Length=189, Percent_Identity=30.6878306878307, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002658
- InterPro:   IPR016037
- InterPro:   IPR003695 [H]

Pfam domain/function: PF01761 DHQ_synthase; PF02541 Ppx-GppA [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 35165; Mature: 35165

Theoretical pI: Translated: 9.97; Mature: 9.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNLVIVDLGSNSARMAINSIADDGTFREIKRVKEDSRISEGMGRERLLRPQAMNRTIAA
CCCEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHH
LRRFKEIYEEYPNTEVRGITTAAVRMARNQNDFLNRVKQETGIKLHVLSGDDEAYYDYLG
HHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEECCCCHHHHHHHH
VINSLEVKDCLILDTGGASCELIDVHNGKARNMISIPIGAVSLSERFRLTDVVRADNLFA
HHCCCCCCEEEEEECCCCCEEEEECCCCCCCCEEEECCCEEEHHHHHHHHHHHHCCCEEE
AEIFVNKQLRDVWWIMDAFNKPIVLLGGANRTLARMNRRHQKISRINNIHGYRLKTESVN
EHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCEEEEHHHHH
RTFKSLITRNLEARKKMSGLETTRADIIVGGMLPLVMLLQMIDADRVIFSESGVREGIIS
HHHHHHHHHCHHHHHHHHCCCHHHHHEEEHHHHHHHHHHHHHCCCCEEECCCCCHHHHHH
EYINFRKEE
HHHHHCCCC
>Mature Secondary Structure
MKNLVIVDLGSNSARMAINSIADDGTFREIKRVKEDSRISEGMGRERLLRPQAMNRTIAA
CCCEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHH
LRRFKEIYEEYPNTEVRGITTAAVRMARNQNDFLNRVKQETGIKLHVLSGDDEAYYDYLG
HHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEECCCCHHHHHHHH
VINSLEVKDCLILDTGGASCELIDVHNGKARNMISIPIGAVSLSERFRLTDVVRADNLFA
HHCCCCCCEEEEEECCCCCEEEEECCCCCCCCEEEECCCEEEHHHHHHHHHHHHCCCEEE
AEIFVNKQLRDVWWIMDAFNKPIVLLGGANRTLARMNRRHQKISRINNIHGYRLKTESVN
EHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCEEEEHHHHH
RTFKSLITRNLEARKKMSGLETTRADIIVGGMLPLVMLLQMIDADRVIFSESGVREGIIS
HHHHHHHHHCHHHHHHHHCCCHHHHHEEEHHHHHHHHHHHHHCCCCEEECCCCCHHHHHH
EYINFRKEE
HHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11889109 [H]