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The map label for this gene is trpS [H]

Identifier: 116492060

GI number: 116492060

Start: 304896

End: 305924

Strand: Direct

Name: trpS [H]

Synonym: PEPE_0256

Alternate gene names: 116492060

Gene position: 304896-305924 (Clockwise)

Preceding gene: 116492058

Following gene: 116492061

Centisome position: 16.64

GC content: 38.68

Gene sequence:

>1029_bases
ATGACATCTAAAAAAATTATTTTAACTGGTGACCGTCCCACAGGAAAACTTCATATCGGACACTATGTTGGTTCACTTAA
AAACCGCGTTCAACTTCAAAATACAGGTGATTATGAAACTTTCATCATGATTGCTGATATGCAGGCTTTAACTGATAATG
CCCGTGATCCTGAAAAAATCCGTAATAGTCTAATCCAAGTTGCTTTAGACTATTTAGCAGTGGGCATTGATCCAGCTAAA
TCGACGATCTTTGTGCAGTCACAGATTCCAGCACTAAGTGAATTGACTCAACATTATATGAATTTGGTTAGCGTAGCTCG
TTTGGAACGGAATCCAACCGTTAAAACTGAAATTAAACAAAAGGCATTTGGGCAAAGTATTCCAGCTGGTTTCTTTACTT
ATCCGGTTAGTCAAGCTGCCGATATTACAGCCTTTAAAGCAGATACTGTACCAGTAGGGGATGACCAAGAACCCATGCTA
GAACAGACGCGTGAAATTGTACGTTCTTTCAACAATATCTACCAAAAAGAAGTGCTAGTTGAACCAGAAGGATATTTCCC
ACCTAAAGGAATGGGACGAATTCCTGGATTAGACGGAAATGCAAAGATGTCTAAATCATTGGGTAATGCTATTTATTTGG
CAGATGACGAAGAAACTATCCAAAAGAAAGTTATGTCAATGTATACTGATCCTCAACATATTCGGGTAGAAGATCCTGGC
CATATTGAAGGTAATACCGTATTTACTTACCTAGACATCTTTGATCCTGATAAGCAAAAAGTCCAAGAACTTAAAGATCA
GTATCAAGCTGGTGGATTAGGAGACGTTAAAATTAAACGTTACTTAAATGAAGTTCTCCAAAACGAATTACGCCCAATTC
GCGAGCGTCGGGAAAGGTATGAAGCAGATATTGACGCTGTATACCAAATTCTAAAAGACGGTAGTGACAAGGCTAACGCG
GTCGCAGAACAGACTTTAAAGGAAGTTCGAGATGCCATTGGAATTAACTATTTTGATCACCGACTTTAA

Upstream 100 bases:

>100_bases
GCGGTGGCTTTATAATGGAGTCACAAGTTAGGTGGTACCGCGATTTTTCGTCCTATTATTCATTTTTGAATAGTAGGATT
TTTTATATCTGGAGGAAATT

Downstream 100 bases:

>100_bases
TCGTAAAAGCCATGCTTCTAAAAGAAGTGTGGTTTTTTATTAAGGATTAATGTAAACGTTTGTTTTTATTTTAGTTGATA
GGCGAGATGAGCTCCTTTTC

Product: tryptophanyl-tRNA synthetase II

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 342; Mature: 341

Protein sequence:

>342_residues
MTSKKIILTGDRPTGKLHIGHYVGSLKNRVQLQNTGDYETFIMIADMQALTDNARDPEKIRNSLIQVALDYLAVGIDPAK
STIFVQSQIPALSELTQHYMNLVSVARLERNPTVKTEIKQKAFGQSIPAGFFTYPVSQAADITAFKADTVPVGDDQEPML
EQTREIVRSFNNIYQKEVLVEPEGYFPPKGMGRIPGLDGNAKMSKSLGNAIYLADDEETIQKKVMSMYTDPQHIRVEDPG
HIEGNTVFTYLDIFDPDKQKVQELKDQYQAGGLGDVKIKRYLNEVLQNELRPIRERRERYEADIDAVYQILKDGSDKANA
VAEQTLKEVRDAIGINYFDHRL

Sequences:

>Translated_342_residues
MTSKKIILTGDRPTGKLHIGHYVGSLKNRVQLQNTGDYETFIMIADMQALTDNARDPEKIRNSLIQVALDYLAVGIDPAK
STIFVQSQIPALSELTQHYMNLVSVARLERNPTVKTEIKQKAFGQSIPAGFFTYPVSQAADITAFKADTVPVGDDQEPML
EQTREIVRSFNNIYQKEVLVEPEGYFPPKGMGRIPGLDGNAKMSKSLGNAIYLADDEETIQKKVMSMYTDPQHIRVEDPG
HIEGNTVFTYLDIFDPDKQKVQELKDQYQAGGLGDVKIKRYLNEVLQNELRPIRERRERYEADIDAVYQILKDGSDKANA
VAEQTLKEVRDAIGINYFDHRL
>Mature_341_residues
TSKKIILTGDRPTGKLHIGHYVGSLKNRVQLQNTGDYETFIMIADMQALTDNARDPEKIRNSLIQVALDYLAVGIDPAKS
TIFVQSQIPALSELTQHYMNLVSVARLERNPTVKTEIKQKAFGQSIPAGFFTYPVSQAADITAFKADTVPVGDDQEPMLE
QTREIVRSFNNIYQKEVLVEPEGYFPPKGMGRIPGLDGNAKMSKSLGNAIYLADDEETIQKKVMSMYTDPQHIRVEDPGH
IEGNTVFTYLDIFDPDKQKVQELKDQYQAGGLGDVKIKRYLNEVLQNELRPIRERRERYEADIDAVYQILKDGSDKANAV
AEQTLKEVRDAIGINYFDHRL

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=339, Percent_Identity=30.6784660766962, Blast_Score=133, Evalue=2e-31,
Organism=Homo sapiens, GI41352700, Length=173, Percent_Identity=36.9942196531792, Blast_Score=108, Evalue=8e-24,
Organism=Escherichia coli, GI1789786, Length=340, Percent_Identity=35.2941176470588, Blast_Score=174, Evalue=8e-45,
Organism=Caenorhabditis elegans, GI71982793, Length=345, Percent_Identity=29.5652173913043, Blast_Score=136, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI71982800, Length=345, Percent_Identity=29.5652173913043, Blast_Score=136, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6320474, Length=360, Percent_Identity=30.5555555555556, Blast_Score=129, Evalue=5e-31,
Organism=Saccharomyces cerevisiae, GI6324475, Length=316, Percent_Identity=25, Blast_Score=63, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24666151, Length=335, Percent_Identity=30.7462686567164, Blast_Score=141, Evalue=6e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 38613; Mature: 38482

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSKKIILTGDRPTGKLHIGHYVGSLKNRVQLQNTGDYETFIMIADMQALTDNARDPEKI
CCCCCEEEECCCCCCEEEHHHHHHHHHHCEEECCCCCCEEEEEEECHHHHHCCCCCHHHH
RNSLIQVALDYLAVGIDPAKSTIFVQSQIPALSELTQHYMNLVSVARLERNPTVKTEIKQ
HHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
KAFGQSIPAGFFTYPVSQAADITAFKADTVPVGDDQEPMLEQTREIVRSFNNIYQKEVLV
HHHCCCCCCCHHHCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEE
EPEGYFPPKGMGRIPGLDGNAKMSKSLGNAIYLADDEETIQKKVMSMYTDPQHIRVEDPG
CCCCCCCCCCCCCCCCCCCCCHHHHHCCCEEEEECCHHHHHHHHHHHCCCCCEEEECCCC
HIEGNTVFTYLDIFDPDKQKVQELKDQYQAGGLGDVKIKRYLNEVLQNELRPIRERRERY
CCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EADIDAVYQILKDGSDKANAVAEQTLKEVRDAIGINYFDHRL
CCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHCCC
>Mature Secondary Structure 
TSKKIILTGDRPTGKLHIGHYVGSLKNRVQLQNTGDYETFIMIADMQALTDNARDPEKI
CCCCEEEECCCCCCEEEHHHHHHHHHHCEEECCCCCCEEEEEEECHHHHHCCCCCHHHH
RNSLIQVALDYLAVGIDPAKSTIFVQSQIPALSELTQHYMNLVSVARLERNPTVKTEIKQ
HHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
KAFGQSIPAGFFTYPVSQAADITAFKADTVPVGDDQEPMLEQTREIVRSFNNIYQKEVLV
HHHCCCCCCCHHHCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEE
EPEGYFPPKGMGRIPGLDGNAKMSKSLGNAIYLADDEETIQKKVMSMYTDPQHIRVEDPG
CCCCCCCCCCCCCCCCCCCCCHHHHHCCCEEEEECCHHHHHHHHHHHCCCCCEEEECCCC
HIEGNTVFTYLDIFDPDKQKVQELKDQYQAGGLGDVKIKRYLNEVLQNELRPIRERRERY
CCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EADIDAVYQILKDGSDKANAVAEQTLKEVRDAIGINYFDHRL
CCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA