Click here to switch to the map view.

The map label for this gene is hslV

Identifier: 116515290

GI number: 116515290

Start: 395540

End: 396076

Strand: Direct

Name: hslV

Synonym: BCc_376

Alternate gene names: 116515290

Gene position: 395540-396076 (Clockwise)

Preceding gene: 116515288

Following gene: 116515291

Centisome position: 94.99

GC content: 31.47

Gene sequence:

>537_bases
ATGACTACTATATTAAGTGTGAGAGTACAAGGAAAAGTAGTTATTGGTGGGGATGGACAAGCTACTTTCGGACATACTGT
TATGAAAAGCAACGTAAAGAAAGTTCGTTCAATTTATAAAAATCAAGTTATTGCTGGTTTTGCTGGAGGAACAGCCGATG
CTTTTACTTTATTTGAATTATTTGAAAAAAAACTAGAAAAATATCAAGGACAATTACAACGATCTGCAATAGAATTAGCG
AAAGATTGGAGAACTGATCGTTTATTAAGAAAACTTGAAGCGCTATTAGCAGTGGCAGACAAAAAAAATTCTTTAATTAT
TACAGGAACTGGTGATGTAATACAACCTGAAAATGATATTATTGCTATAGGTTCCGGAGGACCATATGCTCAAGCAGCAG
CTTATGCTTATGCTTTAGTATATAATACAAATTTAAAAGCATCGAATATAGTAAAAAAATCACTGCAAATCGCTTCAAAC
ATTTGTATCTACACTAACCAATCATTTACTATAAAAGAAATAAAATCAGAAAAGTAA

Upstream 100 bases:

>100_bases
GCAATATTTTTTAAAATCAATATTTTATTGAATAAAATATATATACATTTTGTACAATTATTTCTTTAAAATAAAAAGAA
TATATTTAAAAAGGTTGTTT

Downstream 100 bases:

>100_bases
TAAGGATACTTACATGTCAGAAATGACTCCAAGAAAAATTGTAAAAGAACTAAACAAATACATTATTGGACAAAATAATG
CTAAACGTGCAGTAGCTATT

Product: ATP-dependent protease peptidase subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 178; Mature: 177

Protein sequence:

>178_residues
MTTILSVRVQGKVVIGGDGQATFGHTVMKSNVKKVRSIYKNQVIAGFAGGTADAFTLFELFEKKLEKYQGQLQRSAIELA
KDWRTDRLLRKLEALLAVADKKNSLIITGTGDVIQPENDIIAIGSGGPYAQAAAYAYALVYNTNLKASNIVKKSLQIASN
ICIYTNQSFTIKEIKSEK

Sequences:

>Translated_178_residues
MTTILSVRVQGKVVIGGDGQATFGHTVMKSNVKKVRSIYKNQVIAGFAGGTADAFTLFELFEKKLEKYQGQLQRSAIELA
KDWRTDRLLRKLEALLAVADKKNSLIITGTGDVIQPENDIIAIGSGGPYAQAAAYAYALVYNTNLKASNIVKKSLQIASN
ICIYTNQSFTIKEIKSEK
>Mature_177_residues
TTILSVRVQGKVVIGGDGQATFGHTVMKSNVKKVRSIYKNQVIAGFAGGTADAFTLFELFEKKLEKYQGQLQRSAIELAK
DWRTDRLLRKLEALLAVADKKNSLIITGTGDVIQPENDIIAIGSGGPYAQAAAYAYALVYNTNLKASNIVKKSLQIASNI
CIYTNQSFTIKEIKSEK

Specific function: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery

COG id: COG5405

COG function: function code O; ATP-dependent protease HslVU (ClpYQ), peptidase subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase T1B family. HslV subfamily

Homologues:

Organism=Escherichia coli, GI1790367, Length=174, Percent_Identity=72.4137931034483, Blast_Score=259, Evalue=9e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HSLV_BUCCC (Q056X3)

Other databases:

- EMBL:   CP000263
- RefSeq:   YP_802919.1
- ProteinModelPortal:   Q056X3
- SMR:   Q056X3
- STRING:   Q056X3
- MEROPS:   T01.006
- EnsemblBacteria:   EBBUCT00000001303
- GeneID:   4440967
- GenomeReviews:   CP000263_GR
- KEGG:   bcc:BCc_376
- eggNOG:   COG5405
- GeneTree:   EBGT00050000007885
- HOGENOM:   HBG288822
- OMA:   AADICVY
- ProtClustDB:   PRK05456
- BioCyc:   BAPH372461:BCC_376-MONOMER
- HAMAP:   MF_00248
- InterPro:   IPR022281
- InterPro:   IPR001353
- TIGRFAMs:   TIGR03692

Pfam domain/function: PF00227 Proteasome

EC number: 3.4.25.-

Molecular weight: Translated: 19449; Mature: 19318

Theoretical pI: Translated: 10.15; Mature: 10.15

Prosite motif: NA

Important sites: ACT_SITE 2-2

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTILSVRVQGKVVIGGDGQATFGHTVMKSNVKKVRSIYKNQVIAGFAGGTADAFTLFEL
CCEEEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHH
FEKKLEKYQGQLQRSAIELAKDWRTDRLLRKLEALLAVADKKNSLIITGTGDVIQPENDI
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEEECCCEECCCCCE
IAIGSGGPYAQAAAYAYALVYNTNLKASNIVKKSLQIASNICIYTNQSFTIKEIKSEK
EEEECCCCHHHHHHHEEEEEEECCCCHHHHHHHHHHHHCCEEEEECCCEEEHHCCCCC
>Mature Secondary Structure 
TTILSVRVQGKVVIGGDGQATFGHTVMKSNVKKVRSIYKNQVIAGFAGGTADAFTLFEL
CEEEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHH
FEKKLEKYQGQLQRSAIELAKDWRTDRLLRKLEALLAVADKKNSLIITGTGDVIQPENDI
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEEECCCEECCCCCE
IAIGSGGPYAQAAAYAYALVYNTNLKASNIVKKSLQIASNICIYTNQSFTIKEIKSEK
EEEECCCCHHHHHHHEEEEEEECCCCHHHHHHHHHHHHCCEEEEECCCEEEHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA