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The map label for this gene is dut [H]

Identifier: 116515282

GI number: 116515282

Start: 389450

End: 389854

Strand: Reverse

Name: dut [H]

Synonym: BCc_367

Alternate gene names: 116515282

Gene position: 389854-389450 (Counterclockwise)

Preceding gene: 116515283

Following gene: 116515281

Centisome position: 93.63

GC content: 15.06

Gene sequence:

>405_bases
ATGAAAAAATTAAATATTAATGTTAAAATTTTTGATACCAGAATTGGTACTGTTTTTCCATTTCCTGAAATTATATCTGG
TGATATATCAGGTTTTTTTTTACGAGCATGTATAAAAAAAAAAATATATATTGATATTAATCAAACTTTTTTAATTCCAA
CTGGAATATTATTATATATATTTAAAAATAATATTAATATTAATATTAAATCTTTTTTTAAATGTAAAAATAATAAAAAA
ATAGTTTTAGGAAATTTTTATAATTTTATAAATTTTTTTAATCCTGGAGAATTAAAGATTTCTTTTTGGAATTGTAGTAA
AAAAAAAATTTGTATTAAACCTGGAGATAAAATTGCAAAAGTATTTATTTTTTCAAATAAAAAAATTAAATTTATATATT
TATAA

Upstream 100 bases:

>100_bases
TACAGTTTTATTTACACCATATAAAAATATTTCTACAGAATTTAAAGTAGTTATTCTATCAAAATAGATTTTTTAATTTA
AAATTTTTTTTTAAATAAGT

Downstream 100 bases:

>100_bases
AAATAAAATTTAATATAAAATATTTATGAAATAAGGATATATATATTATTAATAATAAATATTTATATATGAAAAACATA
ATAATATGGCCCTTGCTGGA

Product: hypothetical protein

Products: NA

Alternate protein names: dUTPase; dUTP pyrophosphatase [H]

Number of amino acids: Translated: 134; Mature: 134

Protein sequence:

>134_residues
MKKLNINVKIFDTRIGTVFPFPEIISGDISGFFLRACIKKKIYIDINQTFLIPTGILLYIFKNNININIKSFFKCKNNKK
IVLGNFYNFINFFNPGELKISFWNCSKKKICIKPGDKIAKVFIFSNKKIKFIYL

Sequences:

>Translated_134_residues
MKKLNINVKIFDTRIGTVFPFPEIISGDISGFFLRACIKKKIYIDINQTFLIPTGILLYIFKNNININIKSFFKCKNNKK
IVLGNFYNFINFFNPGELKISFWNCSKKKICIKPGDKIAKVFIFSNKKIKFIYL
>Mature_134_residues
MKKLNINVKIFDTRIGTVFPFPEIISGDISGFFLRACIKKKIYIDINQTFLIPTGILLYIFKNNININIKSFFKCKNNKK
IVLGNFYNFINFFNPGELKISFWNCSKKKICIKPGDKIAKVFIFSNKKIKFIYL

Specific function: This enzyme is involved in nucleotide metabolism:it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA [H]

COG id: COG0756

COG function: function code F; dUTPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dUTPase family [H]

Homologues:

Organism=Escherichia coli, GI1790071, Length=121, Percent_Identity=33.8842975206612, Blast_Score=84, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008180
- InterPro:   IPR008181 [H]

Pfam domain/function: PF00692 dUTPase [H]

EC number: =3.6.1.23 [H]

Molecular weight: Translated: 15678; Mature: 15678

Theoretical pI: Translated: 10.70; Mature: 10.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLNINVKIFDTRIGTVFPFPEIISGDISGFFLRACIKKKIYIDINQTFLIPTGILLYI
CCEEEEEEEEEEEECCEECCCHHHHCCCCCHHHHHHHHCEEEEEEECCEEEECCCEEEEE
FKNNININIKSFFKCKNNKKIVLGNFYNFINFFNPGELKISFWNCSKKKICIKPGDKIAK
EECCCEEEEEEEEEECCCCEEEEECCCCEEECCCCCEEEEEEECCCCEEEEECCCCCEEE
VFIFSNKKIKFIYL
EEEECCCEEEEEEC
>Mature Secondary Structure
MKKLNINVKIFDTRIGTVFPFPEIISGDISGFFLRACIKKKIYIDINQTFLIPTGILLYI
CCEEEEEEEEEEEECCEECCCHHHHCCCCCHHHHHHHHCEEEEEEECCEEEECCCEEEEE
FKNNININIKSFFKCKNNKKIVLGNFYNFINFFNPGELKISFWNCSKKKICIKPGDKIAK
EECCCEEEEEEEEEECCCCEEEEECCCCEEECCCCCEEEEEEECCCCEEEEECCCCCEEE
VFIFSNKKIKFIYL
EEEECCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA