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The map label for this gene is trpS [H]

Identifier: 116515268

GI number: 116515268

Start: 375256

End: 376272

Strand: Reverse

Name: trpS [H]

Synonym: BCc_350

Alternate gene names: 116515268

Gene position: 376272-375256 (Counterclockwise)

Preceding gene: 116515269

Following gene: 116515267

Centisome position: 90.37

GC content: 19.27

Gene sequence:

>1017_bases
ATGAAGTTTTCTAAAGAAAAAGAAATTATGTTTACTGGAATTCAACCTTCAGGTAGTTTAACTTTAGGTAATTACTGTGG
AACAATGTGTAATTGGTATAATTTACAAAAAAAATATAAATGTTTTTTTTGTATTTCAGATTTACATGCTCTTAATACTA
TTCAAAAAGCAAGTAAAAAATATAAATTTTTTGACAAAATTCTTGATTTAGTTGCTTTATATTTATCATGTGGAGTTAAT
CCTAAAAAAAGTATTATTTTTGTTCAATCTCAAGTACATACACATAGTCAGTTATATTGGATTTTGAGTAATTTTACTTA
TTTCGGGGAATTATCTCGTATGACTCAATTTAAAAAAAAAAAAGAATTATTAAATAATAAAGAAATTGATTTAGCATTAT
TTTGTTATCCAGTTTTAATGGCAGCAGATATTTTATTATATAAAACAAATTTTGTTTCTATCGGTTTAGATCAAAAACAA
CATTTAGAATTAGTACAAAATATTGCATATCGTTTTAATCGTATATATAAAGATATTTTTGTTATTCCTAAAATATTAAT
TAAATCTATTGGATCTAAAATAATGGCGTTACAAGAACCGAAAAAAAAAATGTCAAAATCAGATGTCAATATAAAGAATA
CAATTTTTTTATTAGATAATATTGATTTAATACGTTTAAAATTACAAAAATCATTAACTGATTCAGATAAATCAGCCAAA
ATTATATATGATACTCGAAAAAAACCTGGTATTTCTAATTTATTATCAATTTTTTCATCAATTACAAAAAAAACAATTTT
TAATTTAGAAAATGAATTTAAATATACAAAATATTCAATTTTTAAAAAAAATTTATCAGATGTTGTATGTGATACAATTT
CTAATATACAAAAATCATATTTTTATTTTAGAAAAAATAAAGATTATTTAATTGATATTATTAATTTAGGAAAAAAATAT
GCATTAAATGATAGTTTAAAAAATTTATTTAAAATTTATAAAAAATTAGGATTTTAA

Upstream 100 bases:

>100_bases
AAATTATTTAAAAACAATAAAAAATTTTCAAAATATTTTTTTTTAATTTTTATTTTTTAAAAATTAAAATATATAATAAA
ATATTATTAAGGATTTATAT

Downstream 100 bases:

>100_bases
TATTAAATATTTTTTTTAAAAAATTAAAATTGTTTTTTAAATTAGATAATTATTTAATATAAATAGATTTTTAATATTAT
AAAGATTTTTAAATAATGAA

Product: hypothetical protein

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MKFSKEKEIMFTGIQPSGSLTLGNYCGTMCNWYNLQKKYKCFFCISDLHALNTIQKASKKYKFFDKILDLVALYLSCGVN
PKKSIIFVQSQVHTHSQLYWILSNFTYFGELSRMTQFKKKKELLNNKEIDLALFCYPVLMAADILLYKTNFVSIGLDQKQ
HLELVQNIAYRFNRIYKDIFVIPKILIKSIGSKIMALQEPKKKMSKSDVNIKNTIFLLDNIDLIRLKLQKSLTDSDKSAK
IIYDTRKKPGISNLLSIFSSITKKTIFNLENEFKYTKYSIFKKNLSDVVCDTISNIQKSYFYFRKNKDYLIDIINLGKKY
ALNDSLKNLFKIYKKLGF

Sequences:

>Translated_338_residues
MKFSKEKEIMFTGIQPSGSLTLGNYCGTMCNWYNLQKKYKCFFCISDLHALNTIQKASKKYKFFDKILDLVALYLSCGVN
PKKSIIFVQSQVHTHSQLYWILSNFTYFGELSRMTQFKKKKELLNNKEIDLALFCYPVLMAADILLYKTNFVSIGLDQKQ
HLELVQNIAYRFNRIYKDIFVIPKILIKSIGSKIMALQEPKKKMSKSDVNIKNTIFLLDNIDLIRLKLQKSLTDSDKSAK
IIYDTRKKPGISNLLSIFSSITKKTIFNLENEFKYTKYSIFKKNLSDVVCDTISNIQKSYFYFRKNKDYLIDIINLGKKY
ALNDSLKNLFKIYKKLGF
>Mature_338_residues
MKFSKEKEIMFTGIQPSGSLTLGNYCGTMCNWYNLQKKYKCFFCISDLHALNTIQKASKKYKFFDKILDLVALYLSCGVN
PKKSIIFVQSQVHTHSQLYWILSNFTYFGELSRMTQFKKKKELLNNKEIDLALFCYPVLMAADILLYKTNFVSIGLDQKQ
HLELVQNIAYRFNRIYKDIFVIPKILIKSIGSKIMALQEPKKKMSKSDVNIKNTIFLLDNIDLIRLKLQKSLTDSDKSAK
IIYDTRKKPGISNLLSIFSSITKKTIFNLENEFKYTKYSIFKKNLSDVVCDTISNIQKSYFYFRKNKDYLIDIINLGKKY
ALNDSLKNLFKIYKKLGF

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=333, Percent_Identity=34.2342342342342, Blast_Score=212, Evalue=5e-55,
Organism=Homo sapiens, GI41352700, Length=179, Percent_Identity=44.1340782122905, Blast_Score=156, Evalue=2e-38,
Organism=Escherichia coli, GI1789786, Length=332, Percent_Identity=46.0843373493976, Blast_Score=316, Evalue=1e-87,
Organism=Caenorhabditis elegans, GI71982800, Length=342, Percent_Identity=32.4561403508772, Blast_Score=189, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI71982793, Length=342, Percent_Identity=32.4561403508772, Blast_Score=188, Evalue=4e-48,
Organism=Saccharomyces cerevisiae, GI6320474, Length=346, Percent_Identity=36.4161849710983, Blast_Score=223, Evalue=4e-59,
Organism=Drosophila melanogaster, GI24666151, Length=333, Percent_Identity=35.7357357357357, Blast_Score=226, Evalue=2e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 39501; Mature: 39501

Theoretical pI: Translated: 10.22; Mature: 10.22

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFSKEKEIMFTGIQPSGSLTLGNYCGTMCNWYNLQKKYKCFFCISDLHALNTIQKASKK
CCCCCCCCEEEEECCCCCCEEEHHHHHHHHHHHHHHHHHEEEEEHHHHHHHHHHHHHHHH
YKFFDKILDLVALYLSCGVNPKKSIIFVQSQVHTHSQLYWILSNFTYFGELSRMTQFKKK
HHHHHHHHHHHHHHHHCCCCCCCCEEEEECHHCHHHHHHHHHHCCHHHHHHHHHHHHHHH
KELLNNKEIDLALFCYPVLMAADILLYKTNFVSIGLDQKQHLELVQNIAYRFNRIYKDIF
HHHHCCCCCHHHHHHHHHHHHHHHHHEECCEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
VIPKILIKSIGSKIMALQEPKKKMSKSDVNIKNTIFLLDNIDLIRLKLQKSLTDSDKSAK
HHHHHHHHHHCHHHHHHHCHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHCCCCCCCCE
IIYDTRKKPGISNLLSIFSSITKKTIFNLENEFKYTKYSIFKKNLSDVVCDTISNIQKSY
EEEECCCCCCHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FYFRKNKDYLIDIINLGKKYALNDSLKNLFKIYKKLGF
HHEECCCCCEEEHHHCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKFSKEKEIMFTGIQPSGSLTLGNYCGTMCNWYNLQKKYKCFFCISDLHALNTIQKASKK
CCCCCCCCEEEEECCCCCCEEEHHHHHHHHHHHHHHHHHEEEEEHHHHHHHHHHHHHHHH
YKFFDKILDLVALYLSCGVNPKKSIIFVQSQVHTHSQLYWILSNFTYFGELSRMTQFKKK
HHHHHHHHHHHHHHHHCCCCCCCCEEEEECHHCHHHHHHHHHHCCHHHHHHHHHHHHHHH
KELLNNKEIDLALFCYPVLMAADILLYKTNFVSIGLDQKQHLELVQNIAYRFNRIYKDIF
HHHHCCCCCHHHHHHHHHHHHHHHHHEECCEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
VIPKILIKSIGSKIMALQEPKKKMSKSDVNIKNTIFLLDNIDLIRLKLQKSLTDSDKSAK
HHHHHHHHHHCHHHHHHHCHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHCCCCCCCCE
IIYDTRKKPGISNLLSIFSSITKKTIFNLENEFKYTKYSIFKKNLSDVVCDTISNIQKSY
EEEECCCCCCHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FYFRKNKDYLIDIINLGKKYALNDSLKNLFKIYKKLGF
HHEECCCCCEEEHHHCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12089438 [H]