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The map label for this gene is fmt [H]

Identifier: 116515232

GI number: 116515232

Start: 354529

End: 355485

Strand: Direct

Name: fmt [H]

Synonym: BCc_314

Alternate gene names: 116515232

Gene position: 354529-355485 (Clockwise)

Preceding gene: 116515231

Following gene: 116515273

Centisome position: 85.15

GC content: 19.85

Gene sequence:

>957_bases
ATGTTAAAAAAAAAAACAAAAATAATTTTTGCTGGAAGCGATAAATTTTCATTAGCACATCTTCGATCATTATTTTTTTC
CCAAAATATTATTTCAGCTGTTTTAACAAAACCAGATAATCAATATTTTAAAAAAAAAAAAAAAGCATTTTCTTCTGTAA
AAAATTTTTCTATTAAAAATAAAATAAAAATATTTCAACCAAAAGATTTATATGAAGAAAAATTTTACTTAAATATTAAA
AAAATAAATCCTGATTTATTAATTGTATCATCTTATGGAATGATAATTCCAAAAAAAATATTACAACTATTTCCTTTAGG
AGGTATTAATGTACATGCTTCTTTATTACCAAAATGGAAAGGAGCTGCTCCTATACAACGATCTATTCTTCATGGTGATA
AAAAAACTGGAATTAGCGTTATAAAAATGAATTCAAAAATGGATTCTGGAAAAATAATTTATCAATTATCTTGTCCTATA
TATTATAATGATAATACTAAAAAATTATCTATCAGATTGATACCTATTTCTTTACAATGTATGTATCAAGCATTAAATAT
TATCTTAAGTAAAAAAAAAAAAAAATTTCATAAGCAAAAAAGAAATCAAGAAACTTTTGCATTAAAAATAAAAAAAGAAG
AAGCAATTATTTCATGGTCACAAACTGTTATAGAAATAGATCGAAAAATTCGAGCGTTTAGTTTATGGCCGATTTGTAAA
TTTTTTTTTAAAAAATTATTAATACAAATTAAAAAATCATCAATTATTTCTATTAAAAAAAATAATTTTAAAAATGGAGA
AATAGTTAATATCACAAAAAAAGGAGTACAAGTAAATACAAAAACTGGTATATTAAATATAGAAAAAATTAAAATTCCAG
GAAAAAAAACAATGTATATACATGAAATATTAAATTCAAGAAGAAAAATGTTTATTAAAAATAAAATATTAAAATAA

Upstream 100 bases:

>100_bases
CAATATGCATTCAACATGAAATAGATCATTTAATTGGAAAATTATTTATAGATTATATTAATTAATACCAAAATTTTCTA
TAATAATTATTATTAAACAT

Downstream 100 bases:

>100_bases
TTCTTCTATAATTAAAAATTATATATTTTTTTAAAAAAAAGAACGGCATAAAAATGCCGTTTTTATTTAACTAATATATT
AAAAAATAAATTATTTTTAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MLKKKTKIIFAGSDKFSLAHLRSLFFSQNIISAVLTKPDNQYFKKKKKAFSSVKNFSIKNKIKIFQPKDLYEEKFYLNIK
KINPDLLIVSSYGMIIPKKILQLFPLGGINVHASLLPKWKGAAPIQRSILHGDKKTGISVIKMNSKMDSGKIIYQLSCPI
YYNDNTKKLSIRLIPISLQCMYQALNIILSKKKKKFHKQKRNQETFALKIKKEEAIISWSQTVIEIDRKIRAFSLWPICK
FFFKKLLIQIKKSSIISIKKNNFKNGEIVNITKKGVQVNTKTGILNIEKIKIPGKKTMYIHEILNSRRKMFIKNKILK

Sequences:

>Translated_318_residues
MLKKKTKIIFAGSDKFSLAHLRSLFFSQNIISAVLTKPDNQYFKKKKKAFSSVKNFSIKNKIKIFQPKDLYEEKFYLNIK
KINPDLLIVSSYGMIIPKKILQLFPLGGINVHASLLPKWKGAAPIQRSILHGDKKTGISVIKMNSKMDSGKIIYQLSCPI
YYNDNTKKLSIRLIPISLQCMYQALNIILSKKKKKFHKQKRNQETFALKIKKEEAIISWSQTVIEIDRKIRAFSLWPICK
FFFKKLLIQIKKSSIISIKKNNFKNGEIVNITKKGVQVNTKTGILNIEKIKIPGKKTMYIHEILNSRRKMFIKNKILK
>Mature_318_residues
MLKKKTKIIFAGSDKFSLAHLRSLFFSQNIISAVLTKPDNQYFKKKKKAFSSVKNFSIKNKIKIFQPKDLYEEKFYLNIK
KINPDLLIVSSYGMIIPKKILQLFPLGGINVHASLLPKWKGAAPIQRSILHGDKKTGISVIKMNSKMDSGKIIYQLSCPI
YYNDNTKKLSIRLIPISLQCMYQALNIILSKKKKKFHKQKRNQETFALKIKKEEAIISWSQTVIEIDRKIRAFSLWPICK
FFFKKLLIQIKKSSIISIKKNNFKNGEIVNITKKGVQVNTKTGILNIEKIKIPGKKTMYIHEILNSRRKMFIKNKILK

Specific function: Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by:(I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-

COG id: COG0223

COG function: function code J; Methionyl-tRNA formyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fmt family [H]

Homologues:

Organism=Homo sapiens, GI164663775, Length=235, Percent_Identity=25.531914893617, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI238814322, Length=240, Percent_Identity=27.5, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI21614513, Length=154, Percent_Identity=30.5194805194805, Blast_Score=77, Evalue=1e-14,
Organism=Escherichia coli, GI1789683, Length=316, Percent_Identity=36.0759493670886, Blast_Score=229, Evalue=1e-61,
Organism=Escherichia coli, GI1788589, Length=231, Percent_Identity=26.8398268398268, Blast_Score=101, Evalue=5e-23,
Organism=Saccharomyces cerevisiae, GI6319458, Length=280, Percent_Identity=24.6428571428571, Blast_Score=74, Evalue=2e-14,
Organism=Drosophila melanogaster, GI45550868, Length=235, Percent_Identity=33.6170212765957, Blast_Score=98, Evalue=6e-21,
Organism=Drosophila melanogaster, GI28571984, Length=173, Percent_Identity=36.9942196531792, Blast_Score=93, Evalue=2e-19,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005794
- InterPro:   IPR005793
- InterPro:   IPR002376
- InterPro:   IPR011034
- InterPro:   IPR015518 [H]

Pfam domain/function: PF02911 Formyl_trans_C; PF00551 Formyl_trans_N [H]

EC number: =2.1.2.9 [H]

Molecular weight: Translated: 36881; Mature: 36881

Theoretical pI: Translated: 11.06; Mature: 11.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKKKTKIIFAGSDKFSLAHLRSLFFSQNIISAVLTKPDNQYFKKKKKAFSSVKNFSIKN
CCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCC
KIKIFQPKDLYEEKFYLNIKKINPDLLIVSSYGMIIPKKILQLFPLGGINVHASLLPKWK
CEEEECCCCCCCCEEEEEEEEECCCEEEEECCCCHHHHHHHHHCCCCCCEEEHEECCCCC
GAAPIQRSILHGDKKTGISVIKMNSKMDSGKIIYQLSCPIYYNDNTKKLSIRLIPISLQC
CCCHHHHHHHCCCCCCCEEEEEECCCCCCCCEEEEEECCEEECCCCEEEEEEEEEEHHHH
MYQALNIILSKKKKKFHKQKRNQETFALKIKKEEAIISWSQTVIEIDRKIRAFSLWPICK
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHEEEHHHHHH
FFFKKLLIQIKKSSIISIKKNNFKNGEIVNITKKGVQVNTKTGILNIEKIKIPGKKTMYI
HHHHHHHHHHHCCCEEEEECCCCCCCCEEEEEECCEEEECCCCEEEEEEEECCCCCEEHH
HEILNSRRKMFIKNKILK
HHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLKKKTKIIFAGSDKFSLAHLRSLFFSQNIISAVLTKPDNQYFKKKKKAFSSVKNFSIKN
CCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCC
KIKIFQPKDLYEEKFYLNIKKINPDLLIVSSYGMIIPKKILQLFPLGGINVHASLLPKWK
CEEEECCCCCCCCEEEEEEEEECCCEEEEECCCCHHHHHHHHHCCCCCCEEEHEECCCCC
GAAPIQRSILHGDKKTGISVIKMNSKMDSGKIIYQLSCPIYYNDNTKKLSIRLIPISLQC
CCCHHHHHHHCCCCCCCEEEEEECCCCCCCCEEEEEECCEEECCCCEEEEEEEEEEHHHH
MYQALNIILSKKKKKFHKQKRNQETFALKIKKEEAIISWSQTVIEIDRKIRAFSLWPICK
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHEEEHHHHHH
FFFKKLLIQIKKSSIISIKKNNFKNGEIVNITKKGVQVNTKTGILNIEKIKIPGKKTMYI
HHHHHHHHHHHCCCEEEEECCCCCCCCEEEEEECCEEEECCCCEEEEEEEECCCCCEEHH
HEILNSRRKMFIKNKILK
HHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA