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The map label for this gene is ffh [H]

Identifier: 116515177

GI number: 116515177

Start: 280008

End: 281354

Strand: Direct

Name: ffh [H]

Synonym: BCc_245

Alternate gene names: 116515177

Gene position: 280008-281354 (Clockwise)

Preceding gene: 116515176

Following gene: 116515178

Centisome position: 67.25

GC content: 18.34

Gene sequence:

>1347_bases
ATGTTTAATAATTTAACAAAAAAAATAACTAATATTTTTGATAAAATATCATATAAAAGTTATTTAGAAAAAAAAACAAT
AAAAAAAACATTAAATAAAATAAAGTTAGCATTTTTAGATGCAGATGTTGCATTAAATGTAATTAAATTATTTTTAAAAA
AAATAAAAAAAAAAATAAAAAAAAAAAAAATTAATAAAAATTTAAGTCCTAGTCAAAATTTAATAAATATAATACTAAAA
GAATTAATTAAAATTTTAGGAAAAAATCATTATTCTTTTAATTTTTTATTTAATCAATTAAATATTTGTACTGTTATTGG
TCAACAGGGGGTAGGAAAAACGACGAGCACTGCAAAATTAGCATATTTATTAACAAAAAAATATAAAAAAAAAGTCTTAG
TAGTATCCACTGATATATATAGACCAGCTGCTATTGTTCAATTAAAAAGATTAATAGAAAAAACAAAAGCAAATTTTTTT
CCATCTGTAGTAACACAAAAAATAATGACTATTATTAAATCAGCTATTAAAGAAGCTAAAAGAAAAAAATATGATGTATT
ATTAATTGACACAGCAGGAAGATTACATAACAATAGTAAAAAAATTCAAGAATTAAAAAAAATACAAGAATATACTCAAC
CAAATGAAACATTGTTAATTATTGATTCTATGATAGGGCAAGATTCAATTAATTTAATTAATAAGTTTAATAAAGAATTT
AATTTATCAGGAATTATTCTAACAAAATTAGATAGTGATACAAGAGGAGGAGTTGCATTATCAATTCGTACATTAACAAA
AAAACCAATAAAATATATTGGAACTGGAGAAAAAATTTATGATTTACAAATTTTTCATCCTGAAAGAATTGCAAAAAGAA
TTTTAGGAATGGGAGATGTAATCTCTTTAATAGAAGATATTCAAGATAAAATAAAAAAAAAAGAACTAAATTTATTAAAT
GAAACTACAAAAAAAGGAAAAATTTATAATTTAAATGATTTTTTAATACAAATTAAACAAATTAAAAAGATTGGAGGAAT
TAATTCATTAATTAATAAATTACCAATAAATATAATTTCTTCTAATTCATTATTCAATGATATAGATGAAAAATCTTTTA
TAAAAATTGAAGCTATGATTAATTCTATGACTAAAAAAGAAAGAGAATTTCCTACAATTATAAAAGCTTCTCGAAAAAAA
AGAATTTCATTAGGTTCAGGAAATACTATACAAGAAATTAATATTTATTTAAAAAAATTTGAAAATATTAAACGAATTAT
GAAAAAAATTAAAACAAATAAAAAAAACAAAATATTTGAAAGTATTAAAAATTATTTAATAAAATAG

Upstream 100 bases:

>100_bases
TAATAGTATAAAATAATTGTAAATTAATATTTATTAAAAAATAAAAAATTTTATATTACAATAATAATTATAACTTGTAT
AAAGGAACAAAATAATAATT

Downstream 100 bases:

>100_bases
ATAATATTTTTATATTATGCAAATATTATTTTAAATTATAGAACAGGAAAAAAAATGATCAAAATAAGATTATCTAGACA
TGGAATGAAAAAAAAACCAT

Product: hypothetical protein

Products: NA

Alternate protein names: Fifty-four homolog [H]

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MFNNLTKKITNIFDKISYKSYLEKKTIKKTLNKIKLAFLDADVALNVIKLFLKKIKKKIKKKKINKNLSPSQNLINIILK
ELIKILGKNHYSFNFLFNQLNICTVIGQQGVGKTTSTAKLAYLLTKKYKKKVLVVSTDIYRPAAIVQLKRLIEKTKANFF
PSVVTQKIMTIIKSAIKEAKRKKYDVLLIDTAGRLHNNSKKIQELKKIQEYTQPNETLLIIDSMIGQDSINLINKFNKEF
NLSGIILTKLDSDTRGGVALSIRTLTKKPIKYIGTGEKIYDLQIFHPERIAKRILGMGDVISLIEDIQDKIKKKELNLLN
ETTKKGKIYNLNDFLIQIKQIKKIGGINSLINKLPINIISSNSLFNDIDEKSFIKIEAMINSMTKKEREFPTIIKASRKK
RISLGSGNTIQEINIYLKKFENIKRIMKKIKTNKKNKIFESIKNYLIK

Sequences:

>Translated_448_residues
MFNNLTKKITNIFDKISYKSYLEKKTIKKTLNKIKLAFLDADVALNVIKLFLKKIKKKIKKKKINKNLSPSQNLINIILK
ELIKILGKNHYSFNFLFNQLNICTVIGQQGVGKTTSTAKLAYLLTKKYKKKVLVVSTDIYRPAAIVQLKRLIEKTKANFF
PSVVTQKIMTIIKSAIKEAKRKKYDVLLIDTAGRLHNNSKKIQELKKIQEYTQPNETLLIIDSMIGQDSINLINKFNKEF
NLSGIILTKLDSDTRGGVALSIRTLTKKPIKYIGTGEKIYDLQIFHPERIAKRILGMGDVISLIEDIQDKIKKKELNLLN
ETTKKGKIYNLNDFLIQIKQIKKIGGINSLINKLPINIISSNSLFNDIDEKSFIKIEAMINSMTKKEREFPTIIKASRKK
RISLGSGNTIQEINIYLKKFENIKRIMKKIKTNKKNKIFESIKNYLIK
>Mature_448_residues
MFNNLTKKITNIFDKISYKSYLEKKTIKKTLNKIKLAFLDADVALNVIKLFLKKIKKKIKKKKINKNLSPSQNLINIILK
ELIKILGKNHYSFNFLFNQLNICTVIGQQGVGKTTSTAKLAYLLTKKYKKKVLVVSTDIYRPAAIVQLKRLIEKTKANFF
PSVVTQKIMTIIKSAIKEAKRKKYDVLLIDTAGRLHNNSKKIQELKKIQEYTQPNETLLIIDSMIGQDSINLINKFNKEF
NLSGIILTKLDSDTRGGVALSIRTLTKKPIKYIGTGEKIYDLQIFHPERIAKRILGMGDVISLIEDIQDKIKKKELNLLN
ETTKKGKIYNLNDFLIQIKQIKKIGGINSLINKLPINIISSNSLFNDIDEKSFIKIEAMINSMTKKEREFPTIIKASRKK
RISLGSGNTIQEINIYLKKFENIKRIMKKIKTNKKNKIFESIKNYLIK

Specific function: Necessary for efficient export of extracytoplasmic proteins. Binds to the signal sequence when it emerges from the ribosomes [H]

COG id: COG0541

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=433, Percent_Identity=26.0969976905312, Blast_Score=172, Evalue=5e-43,
Organism=Homo sapiens, GI226371618, Length=361, Percent_Identity=27.1468144044321, Blast_Score=151, Evalue=9e-37,
Organism=Homo sapiens, GI23308697, Length=307, Percent_Identity=23.4527687296417, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI295424842, Length=307, Percent_Identity=23.4527687296417, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI89061728, Length=135, Percent_Identity=31.8518518518519, Blast_Score=91, Evalue=2e-18,
Organism=Escherichia coli, GI1788963, Length=425, Percent_Identity=46.3529411764706, Blast_Score=418, Evalue=1e-118,
Organism=Escherichia coli, GI1789874, Length=251, Percent_Identity=33.0677290836653, Blast_Score=129, Evalue=5e-31,
Organism=Caenorhabditis elegans, GI17539958, Length=440, Percent_Identity=26.5909090909091, Blast_Score=179, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI193206261, Length=201, Percent_Identity=27.8606965174129, Blast_Score=95, Evalue=9e-20,
Organism=Saccharomyces cerevisiae, GI6325345, Length=412, Percent_Identity=29.8543689320388, Blast_Score=179, Evalue=6e-46,
Organism=Saccharomyces cerevisiae, GI6320498, Length=213, Percent_Identity=28.6384976525822, Blast_Score=90, Evalue=9e-19,
Organism=Drosophila melanogaster, GI17647949, Length=352, Percent_Identity=27.8409090909091, Blast_Score=162, Evalue=4e-40,
Organism=Drosophila melanogaster, GI24641198, Length=203, Percent_Identity=28.5714285714286, Blast_Score=92, Evalue=7e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822
- InterPro:   IPR004780
- InterPro:   IPR004125 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N; PF02978 SRP_SPB [H]

EC number: NA

Molecular weight: Translated: 51553; Mature: 51553

Theoretical pI: Translated: 10.85; Mature: 10.85

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNNLTKKITNIFDKISYKSYLEKKTIKKTLNKIKLAFLDADVALNVIKLFLKKIKKKIK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
KKKINKNLSPSQNLINIILKELIKILGKNHYSFNFLFNQLNICTVIGQQGVGKTTSTAKL
HHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHEEECCCCCCCCCHHHHH
AYLLTKKYKKKVLVVSTDIYRPAAIVQLKRLIEKTKANFFPSVVTQKIMTIIKSAIKEAK
HHHHHHHHHCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
RKKYDVLLIDTAGRLHNNSKKIQELKKIQEYTQPNETLLIIDSMIGQDSINLINKFNKEF
HCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEHHHCCHHHHHHHHHCCCC
NLSGIILTKLDSDTRGGVALSIRTLTKKPIKYIGTGEKIYDLQIFHPERIAKRILGMGDV
CCCEEEEEEECCCCCCCEEEEEEHHHHCCHHHCCCCCEEEEEEEECHHHHHHHHHCCHHH
ISLIEDIQDKIKKKELNLLNETTKKGKIYNLNDFLIQIKQIKKIGGINSLINKLPINIIS
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCHHHHHHHCCCEEEE
SNSLFNDIDEKSFIKIEAMINSMTKKEREFPTIIKASRKKRISLGSGNTIQEINIYLKKF
CCCHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCEEECCCCCCHHHHHHHHHHH
ENIKRIMKKIKTNKKNKIFESIKNYLIK
HHHHHHHHHHHCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MFNNLTKKITNIFDKISYKSYLEKKTIKKTLNKIKLAFLDADVALNVIKLFLKKIKKKIK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
KKKINKNLSPSQNLINIILKELIKILGKNHYSFNFLFNQLNICTVIGQQGVGKTTSTAKL
HHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHEEECCCCCCCCCHHHHH
AYLLTKKYKKKVLVVSTDIYRPAAIVQLKRLIEKTKANFFPSVVTQKIMTIIKSAIKEAK
HHHHHHHHHCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
RKKYDVLLIDTAGRLHNNSKKIQELKKIQEYTQPNETLLIIDSMIGQDSINLINKFNKEF
HCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEHHHCCHHHHHHHHHCCCC
NLSGIILTKLDSDTRGGVALSIRTLTKKPIKYIGTGEKIYDLQIFHPERIAKRILGMGDV
CCCEEEEEEECCCCCCCEEEEEEHHHHCCHHHCCCCCEEEEEEEECHHHHHHHHHCCHHH
ISLIEDIQDKIKKKELNLLNETTKKGKIYNLNDFLIQIKQIKKIGGINSLINKLPINIIS
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCHHHHHHHCCCEEEE
SNSLFNDIDEKSFIKIEAMINSMTKKEREFPTIIKASRKKRISLGSGNTIQEINIYLKKF
CCCHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCEEECCCCCCHHHHHHHHHHH
ENIKRIMKKIKTNKKNKIFESIKNYLIK
HHHHHHHHHHHCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]