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The map label for this gene is gpmA

Identifier: 116515122

GI number: 116515122

Start: 219187

End: 219879

Strand: Direct

Name: gpmA

Synonym: BCc_186

Alternate gene names: 116515122

Gene position: 219187-219879 (Clockwise)

Preceding gene: 116515121

Following gene: 116515123

Centisome position: 52.64

GC content: 22.51

Gene sequence:

>693_bases
ATGAAAAAAAAAAAAATAATATTAATGAGACATGGTGAAAGTAAATGGAATAAGTTAAATAAATTTACTGGATGGCAAGA
TATAGGTTTAACTAAAAATGGAAAAAAAGAAGCAAAACTTGCTGCAAAATTAATAAAAAAAAATAATTTTATATTTGATA
TTGCATATACATCAATTTTAAAAAGAGCTATATATACTTTATGGATAATACTTAAAAAAACAAATCAAATATGGATACCA
GTATATAAATCATGGAAATTAAACGAACGAAATTATGGAGCATTAGAAGGATTAAATAAAGAAAAAATAAAAAAAAAATA
TGGAGATGAACAAGTACAATTATGGAGGAGAAGTTTTACAGTATGTCCACCAAATTTAAATATATCTAATAAATATCATC
CTATTTATGACATAAAATATAAAAAATTAAAAAAACATGAACTTCCTACATCTGAAAGTTTAGAAATGACATTTAATAGA
GTTATTCCATTCTGGGAATTTAAAATTTTACCTCAATTAGAGAAAAATAAAAATATTCTTATTGTTGCTCACGGAAATTC
CTTGCGAGCTTTAATAAAATATTTGGGAAACATAAGTGATTCCGATATAATTGATTTAGATATTTCTACTGGAAAACCGC
TTGTATATGAATTTTCTAATACAAATAAACCATTAAAATATTATTATTTATAA

Upstream 100 bases:

>100_bases
TTAATAAATAATAATTCTTTATATAAATTAATACTTAATTTTATATAAAAAATATATTTTTATAATCAATAATATTTTTA
TTAAAAATCAGGAAAAAAAA

Downstream 100 bases:

>100_bases
CTTTCTAAAACAAAAATTTTGTATATAAATTTATTAGTTTATATATTTTTAAAAATTGAAAATATCAAAAATTTTAATAA
TTTAATAAATGTAAATAAAA

Product: hypothetical protein

Products: NA

Alternate protein names: BPG-dependent PGAM; PGAM; Phosphoglyceromutase; dPGM

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MKKKKIILMRHGESKWNKLNKFTGWQDIGLTKNGKKEAKLAAKLIKKNNFIFDIAYTSILKRAIYTLWIILKKTNQIWIP
VYKSWKLNERNYGALEGLNKEKIKKKYGDEQVQLWRRSFTVCPPNLNISNKYHPIYDIKYKKLKKHELPTSESLEMTFNR
VIPFWEFKILPQLEKNKNILIVAHGNSLRALIKYLGNISDSDIIDLDISTGKPLVYEFSNTNKPLKYYYL

Sequences:

>Translated_230_residues
MKKKKIILMRHGESKWNKLNKFTGWQDIGLTKNGKKEAKLAAKLIKKNNFIFDIAYTSILKRAIYTLWIILKKTNQIWIP
VYKSWKLNERNYGALEGLNKEKIKKKYGDEQVQLWRRSFTVCPPNLNISNKYHPIYDIKYKKLKKHELPTSESLEMTFNR
VIPFWEFKILPQLEKNKNILIVAHGNSLRALIKYLGNISDSDIIDLDISTGKPLVYEFSNTNKPLKYYYL
>Mature_230_residues
MKKKKIILMRHGESKWNKLNKFTGWQDIGLTKNGKKEAKLAAKLIKKNNFIFDIAYTSILKRAIYTLWIILKKTNQIWIP
VYKSWKLNERNYGALEGLNKEKIKKKYGDEQVQLWRRSFTVCPPNLNISNKYHPIYDIKYKKLKKHELPTSESLEMTFNR
VIPFWEFKILPQLEKNKNILIVAHGNSLRALIKYLGNISDSDIIDLDISTGKPLVYEFSNTNKPLKYYYL

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate

COG id: COG0588

COG function: function code G; Phosphoglycerate mutase 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily

Homologues:

Organism=Homo sapiens, GI50593010, Length=231, Percent_Identity=48.9177489177489, Blast_Score=243, Evalue=9e-65,
Organism=Homo sapiens, GI4505753, Length=228, Percent_Identity=43.859649122807, Blast_Score=218, Evalue=4e-57,
Organism=Homo sapiens, GI4502445, Length=223, Percent_Identity=47.5336322869955, Blast_Score=217, Evalue=9e-57,
Organism=Homo sapiens, GI40353764, Length=223, Percent_Identity=47.5336322869955, Blast_Score=217, Evalue=9e-57,
Organism=Homo sapiens, GI71274132, Length=228, Percent_Identity=41.6666666666667, Blast_Score=202, Evalue=2e-52,
Organism=Homo sapiens, GI310129614, Length=165, Percent_Identity=43.030303030303, Blast_Score=154, Evalue=9e-38,
Organism=Escherichia coli, GI1786970, Length=230, Percent_Identity=56.0869565217391, Blast_Score=284, Evalue=4e-78,
Organism=Saccharomyces cerevisiae, GI6322697, Length=227, Percent_Identity=45.8149779735683, Blast_Score=211, Evalue=5e-56,
Organism=Saccharomyces cerevisiae, GI6324516, Length=266, Percent_Identity=36.4661654135338, Blast_Score=132, Evalue=5e-32,
Organism=Saccharomyces cerevisiae, GI6320183, Length=280, Percent_Identity=31.7857142857143, Blast_Score=121, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24646216, Length=226, Percent_Identity=46.4601769911504, Blast_Score=218, Evalue=2e-57,
Organism=Drosophila melanogaster, GI85725270, Length=226, Percent_Identity=46.0176991150442, Blast_Score=209, Evalue=1e-54,
Organism=Drosophila melanogaster, GI85725272, Length=226, Percent_Identity=46.0176991150442, Blast_Score=209, Evalue=1e-54,
Organism=Drosophila melanogaster, GI24650981, Length=226, Percent_Identity=46.0176991150442, Blast_Score=209, Evalue=1e-54,
Organism=Drosophila melanogaster, GI28571817, Length=224, Percent_Identity=35.7142857142857, Blast_Score=163, Evalue=8e-41,
Organism=Drosophila melanogaster, GI24648979, Length=225, Percent_Identity=35.5555555555556, Blast_Score=163, Evalue=9e-41,
Organism=Drosophila melanogaster, GI28571815, Length=224, Percent_Identity=35.7142857142857, Blast_Score=163, Evalue=9e-41,

Paralogues:

None

Copy number: 960 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): GPMA_BUCCC (Q057P1)

Other databases:

- EMBL:   CP000263
- RefSeq:   YP_802751.1
- ProteinModelPortal:   Q057P1
- SMR:   Q057P1
- STRING:   Q057P1
- EnsemblBacteria:   EBBUCT00000001344
- GeneID:   4440797
- GenomeReviews:   CP000263_GR
- KEGG:   bcc:BCc_186
- eggNOG:   COG0588
- GeneTree:   EBGT00050000008044
- HOGENOM:   HBG658938
- OMA:   TGWKDPD
- BioCyc:   BAPH372461:BCC_186-MONOMER
- GO:   GO:0006096
- HAMAP:   MF_01039
- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR005952
- PANTHER:   PTHR11931
- SMART:   SM00855
- TIGRFAMs:   TIGR01258

Pfam domain/function: PF00300 PGAM

EC number: =5.4.2.1

Molecular weight: Translated: 27215; Mature: 27215

Theoretical pI: Translated: 10.51; Mature: 10.51

Prosite motif: PS00175 PG_MUTASE

Important sites: ACT_SITE 11-11 ACT_SITE 184-184

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKKIILMRHGESKWNKLNKFTGWQDIGLTKNGKKEAKLAAKLIKKNNFIFDIAYTSIL
CCCCEEEEEECCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEHHHHHHH
KRAIYTLWIILKKTNQIWIPVYKSWKLNERNYGALEGLNKEKIKKKYGDEQVQLWRRSFT
HHHHHHHEEEEECCCEEEEEEEECEECCCCCCCHHCCCCHHHHHHHHCCHHHHHHHHHCE
VCPPNLNISNKYHPIYDIKYKKLKKHELPTSESLEMTFNRVIPFWEFKILPQLEKNKNIL
ECCCCCCCCCCCCCEEECHHHHHHHHCCCCCCCHHHHHHHCCCEEEEEECCCCCCCCCEE
IVAHGNSLRALIKYLGNISDSDIIDLDISTGKPLVYEFSNTNKPLKYYYL
EEECCCHHHHHHHHHCCCCCCCEEEEEECCCCCEEEEECCCCCCEEEEEC
>Mature Secondary Structure
MKKKKIILMRHGESKWNKLNKFTGWQDIGLTKNGKKEAKLAAKLIKKNNFIFDIAYTSIL
CCCCEEEEEECCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEHHHHHHH
KRAIYTLWIILKKTNQIWIPVYKSWKLNERNYGALEGLNKEKIKKKYGDEQVQLWRRSFT
HHHHHHHEEEEECCCEEEEEEEECEECCCCCCCHHCCCCHHHHHHHHCCHHHHHHHHHCE
VCPPNLNISNKYHPIYDIKYKKLKKHELPTSESLEMTFNRVIPFWEFKILPQLEKNKNIL
ECCCCCCCCCCCCCEEECHHHHHHHHCCCCCCCHHHHHHHCCCEEEEEECCCCCCCCCEE
IVAHGNSLRALIKYLGNISDSDIIDLDISTGKPLVYEFSNTNKPLKYYYL
EEECCCHHHHHHHHHCCCCCCCEEEEEECCCCCEEEEECCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA