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The map label for this gene is grpE1 [H]

Identifier: 116515094

GI number: 116515094

Start: 186323

End: 186913

Strand: Direct

Name: grpE1 [H]

Synonym: BCc_158

Alternate gene names: 116515094

Gene position: 186323-186913 (Clockwise)

Preceding gene: 116515093

Following gene: 116515095

Centisome position: 44.75

GC content: 14.89

Gene sequence:

>591_bases
GTGCTATTTTCTTTAAAATATACTTTTGGAAATATAATTATGAATAATACTGATAATATCAATTCTATATCTTCAGATAA
AAAAAAAAATATAATTAATAAAAATATTATTTTAGAAAAAAAAATTTTATTAGAAAAAAAAACAGAATTACAAAATTTAG
AAGAATATATTAATAAAAAAAAAAATATATATGAAAAAAATATATATAAATTAAAAAAAAGATTACAAAAAAAAATAGAT
AATACCTATAATTTTTTTTTAGAAAAACATTTTTTATCATTATTACCTATCATTGATAGTATTGATTCTTCAATTAATTT
ATTAGATAATTCGAATAATAATTATTCAGATATATATACACAATTAAAAGAAATCAATAAAAATTTTATTTCTATCTTTC
ATAAATATAAAATTTCTGTAATTAATTCTATTAATGTAATTTTTAATCCAGATGTTCATCAGGCTATATCAATTGATTTT
TCTGGAAAATATAAAAATAATTTTGTATCTTCAATTATTCAAAAAGGTTATTTATTAAATAATAGATTGTTACGACCAGC
TTTAGTTTCAGTATCTAAAATATATCAATAA

Upstream 100 bases:

>100_bases
ATATTTACTTTTTCTAAATGTATTTTATTTTTTTAATAAAAATTATATATAAAAATATAATTATAAGTATTTTTATTTAA
AATAATTTATTTATATATTA

Downstream 100 bases:

>100_bases
ATCATATTTAAAAATTTATTTTTAAAAACTATATTTTGTTTTTTATTTTATTTAAGGGAAAAATTTTGAATATTTCTAAA
AAAAAAAAACTTTTTTAAAT

Product: GrpE1

Products: NA

Alternate protein names: HSP-70 cofactor [H]

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MLFSLKYTFGNIIMNNTDNINSISSDKKKNIINKNIILEKKILLEKKTELQNLEEYINKKKNIYEKNIYKLKKRLQKKID
NTYNFFLEKHFLSLLPIIDSIDSSINLLDNSNNNYSDIYTQLKEINKNFISIFHKYKISVINSINVIFNPDVHQAISIDF
SGKYKNNFVSSIIQKGYLLNNRLLRPALVSVSKIYQ

Sequences:

>Translated_196_residues
MLFSLKYTFGNIIMNNTDNINSISSDKKKNIINKNIILEKKILLEKKTELQNLEEYINKKKNIYEKNIYKLKKRLQKKID
NTYNFFLEKHFLSLLPIIDSIDSSINLLDNSNNNYSDIYTQLKEINKNFISIFHKYKISVINSINVIFNPDVHQAISIDF
SGKYKNNFVSSIIQKGYLLNNRLLRPALVSVSKIYQ
>Mature_196_residues
MLFSLKYTFGNIIMNNTDNINSISSDKKKNIINKNIILEKKILLEKKTELQNLEEYINKKKNIYEKNIYKLKKRLQKKID
NTYNFFLEKHFLSLLPIIDSIDSSINLLDNSNNNYSDIYTQLKEINKNFISIFHKYKISVINSINVIFNPDVHQAISIDF
SGKYKNNFVSSIIQKGYLLNNRLLRPALVSVSKIYQ

Specific function: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with dnaK and grpE. It is the nucleotide exchange factor for dnaK and may function as a thermosensor. Unfolded

COG id: COG0576

COG function: function code O; Molecular chaperone GrpE (heat shock protein)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the grpE family [H]

Homologues:

Organism=Escherichia coli, GI1788967, Length=190, Percent_Identity=27.3684210526316, Blast_Score=93, Evalue=9e-21,

Paralogues:

None

Copy number: 2359 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 4,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000740
- InterPro:   IPR013805
- InterPro:   IPR009012 [H]

Pfam domain/function: PF01025 GrpE [H]

EC number: NA

Molecular weight: Translated: 23051; Mature: 23051

Theoretical pI: Translated: 10.23; Mature: 10.23

Prosite motif: PS01071 GRPE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFSLKYTFGNIIMNNTDNINSISSDKKKNIINKNIILEKKILLEKKTELQNLEEYINKK
CEEEEEECCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KNIYEKNIYKLKKRLQKKIDNTYNFFLEKHFLSLLPIIDSIDSSINLLDNSNNNYSDIYT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHH
QLKEINKNFISIFHKYKISVINSINVIFNPDVHQAISIDFSGKYKNNFVSSIIQKGYLLN
HHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCEEEECCCCCHHHHHHHHHHHCCHHHH
NRLLRPALVSVSKIYQ
CCHHHHHHHHHHHHCC
>Mature Secondary Structure
MLFSLKYTFGNIIMNNTDNINSISSDKKKNIINKNIILEKKILLEKKTELQNLEEYINKK
CEEEEEECCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KNIYEKNIYKLKKRLQKKIDNTYNFFLEKHFLSLLPIIDSIDSSINLLDNSNNNYSDIYT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHH
QLKEINKNFISIFHKYKISVINSINVIFNPDVHQAISIDFSGKYKNNFVSSIIQKGYLLN
HHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCEEEECCCCCHHHHHHHHHHHCCHHHH
NRLLRPALVSVSKIYQ
CCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA