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The map label for this gene is ung

Identifier: 116515059

GI number: 116515059

Start: 136126

End: 136809

Strand: Direct

Name: ung

Synonym: BCc_118

Alternate gene names: 116515059

Gene position: 136126-136809 (Clockwise)

Preceding gene: 116515056

Following gene: 116515061

Centisome position: 32.69

GC content: 21.49

Gene sequence:

>684_bases
ATGAAAAATATTTATAAAATTTCATGGTTGGATTTTTTTTTAATAGAAAAAAAAAAAGAATATTTTTTATATTTATTAAA
TAAAATTAAAAATATTAGAAGAAATACAATTGTGTATCCAAAAAAAAATATGGTTTTTAATGCATTTTTATTCACTCCTT
TATCAAGTATTAAAGTTGTTATTTTAGGTCAAGATCCTTATCATAGTGCAGGTCAAGCACATGGATTATCGTTTTCAGTT
CCAAAAGGGGTATTTTTACCTCCTTCTTTAAAAAATATTTTTATAGAATTAAAGAATAATTTTTCCTTTTATAAAAAGAA
CATTCATGGTTGTTTAGAATCTTGGGCAAAACAAGGAGTTTTTTTATTAAATTCTATATTAACAGTTTCAAAAGGTATTC
CAAATTCACATAAAAATTTAGGATGGGAAATTTTTACCGATCAAGTAATTAAATTTATTAGTGATATTTGTAAAGGTGTT
GTATTTTTATTATGGGGAAATATTTCTCAAAAAAAGTATTATTTAATTGATTCAAAAAAACATTTTATATTAAGATCTAC
ACATCCATCACCTTTATCATGTTATAAAGGTTTTTTCGGATGTAATCATTTCTTTAAAACAAATGTTTTATTACAAAATC
AGAAAAAAAAACCAATTAATTGGTTTTTAGATTTATTTGAATAA

Upstream 100 bases:

>100_bases
TATTTTTTAAAAAAATTTATTATACTATAACATATTTTTTGTTTTTTTTTTTTTCATTTTTTATTTGAATTAAATATATT
TAATTATTAAGGTTTATTTT

Downstream 100 bases:

>100_bases
AAATTTTATGAAACATTTTAACTAAAAATTTTATTTTTACAATAAAACAATTGCTTTTTTTATAACTTTATTTTTTAAAA
TATATCCAGGTTTTATAATA

Product: Ung

Products: NA

Alternate protein names: UDG

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MKNIYKISWLDFFLIEKKKEYFLYLLNKIKNIRRNTIVYPKKNMVFNAFLFTPLSSIKVVILGQDPYHSAGQAHGLSFSV
PKGVFLPPSLKNIFIELKNNFSFYKKNIHGCLESWAKQGVFLLNSILTVSKGIPNSHKNLGWEIFTDQVIKFISDICKGV
VFLLWGNISQKKYYLIDSKKHFILRSTHPSPLSCYKGFFGCNHFFKTNVLLQNQKKKPINWFLDLFE

Sequences:

>Translated_227_residues
MKNIYKISWLDFFLIEKKKEYFLYLLNKIKNIRRNTIVYPKKNMVFNAFLFTPLSSIKVVILGQDPYHSAGQAHGLSFSV
PKGVFLPPSLKNIFIELKNNFSFYKKNIHGCLESWAKQGVFLLNSILTVSKGIPNSHKNLGWEIFTDQVIKFISDICKGV
VFLLWGNISQKKYYLIDSKKHFILRSTHPSPLSCYKGFFGCNHFFKTNVLLQNQKKKPINWFLDLFE
>Mature_227_residues
MKNIYKISWLDFFLIEKKKEYFLYLLNKIKNIRRNTIVYPKKNMVFNAFLFTPLSSIKVVILGQDPYHSAGQAHGLSFSV
PKGVFLPPSLKNIFIELKNNFSFYKKNIHGCLESWAKQGVFLLNSILTVSKGIPNSHKNLGWEIFTDQVIKFISDICKGV
VFLLWGNISQKKYYLIDSKKHFILRSTHPSPLSCYKGFFGCNHFFKTNVLLQNQKKKPINWFLDLFE

Specific function: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine

COG id: COG0692

COG function: function code L; Uracil DNA glycosylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uracil-DNA glycosylase family

Homologues:

Organism=Homo sapiens, GI19718751, Length=214, Percent_Identity=50, Blast_Score=218, Evalue=4e-57,
Organism=Homo sapiens, GI6224979, Length=214, Percent_Identity=50, Blast_Score=216, Evalue=9e-57,
Organism=Escherichia coli, GI1788934, Length=218, Percent_Identity=50.9174311926605, Blast_Score=244, Evalue=3e-66,
Organism=Caenorhabditis elegans, GI17556304, Length=218, Percent_Identity=47.2477064220183, Blast_Score=194, Evalue=2e-50,
Organism=Saccharomyces cerevisiae, GI6323620, Length=233, Percent_Identity=40.7725321888412, Blast_Score=157, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UNG_BUCCC (Q057V4)

Other databases:

- EMBL:   CP000263
- RefSeq:   YP_802688.1
- ProteinModelPortal:   Q057V4
- SMR:   Q057V4
- STRING:   Q057V4
- EnsemblBacteria:   EBBUCT00000001373
- GeneID:   4440828
- GenomeReviews:   CP000263_GR
- KEGG:   bcc:BCc_118
- eggNOG:   COG0692
- GeneTree:   EBGT00050000008210
- HOGENOM:   HBG605450
- OMA:   ARAFRQQ
- BioCyc:   BAPH372461:BCC_118-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00148
- InterPro:   IPR002043
- InterPro:   IPR018085
- InterPro:   IPR005122
- Gene3D:   G3DSA:3.40.470.10
- PANTHER:   PTHR11264
- TIGRFAMs:   TIGR00628

Pfam domain/function: PF03167 UDG; SSF52141 UDNA_glycsylseSF

EC number: =3.2.2.27

Molecular weight: Translated: 26515; Mature: 26515

Theoretical pI: Translated: 10.44; Mature: 10.44

Prosite motif: PS00130 U_DNA_GLYCOSYLASE

Important sites: ACT_SITE 65-65

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNIYKISWLDFFLIEKKKEYFLYLLNKIKNIRRNTIVYPKKNMVFNAFLFTPLSSIKVV
CCCEEEEHHHEEEEHHHHHHHHHHHHHHHHHHHHCEEECCCCCCEEEHHHHCCCCCEEEE
ILGQDPYHSAGQAHGLSFSVPKGVFLPPSLKNIFIELKNNFSFYKKNIHGCLESWAKQGV
EEECCCCCCCCCCCCCEEECCCCCCCCCCHHHEEEEECCCHHHHHHHHHHHHHHHHHCCH
FLLNSILTVSKGIPNSHKNLGWEIFTDQVIKFISDICKGVVFLLWGNISQKKYYLIDSKK
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCC
HFILRSTHPSPLSCYKGFFGCNHFFKTNVLLQNQKKKPINWFLDLFE
EEEEECCCCCHHHHHHHHHCCCHHHHCCEEEECCCCCCHHHHHHHCC
>Mature Secondary Structure
MKNIYKISWLDFFLIEKKKEYFLYLLNKIKNIRRNTIVYPKKNMVFNAFLFTPLSSIKVV
CCCEEEEHHHEEEEHHHHHHHHHHHHHHHHHHHHCEEECCCCCCEEEHHHHCCCCCEEEE
ILGQDPYHSAGQAHGLSFSVPKGVFLPPSLKNIFIELKNNFSFYKKNIHGCLESWAKQGV
EEECCCCCCCCCCCCCEEECCCCCCCCCCHHHEEEEECCCHHHHHHHHHHHHHHHHHCCH
FLLNSILTVSKGIPNSHKNLGWEIFTDQVIKFISDICKGVVFLLWGNISQKKYYLIDSKK
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCC
HFILRSTHPSPLSCYKGFFGCNHFFKTNVLLQNQKKKPINWFLDLFE
EEEEECCCCCHHHHHHHHHCCCHHHHCCEEEECCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA