Click here to switch to the map view.

The map label for this gene is nuoH [H]

Identifier: 116515044

GI number: 116515044

Start: 118905

End: 119843

Strand: Direct

Name: nuoH [H]

Synonym: BCc_103

Alternate gene names: 116515044

Gene position: 118905-119843 (Clockwise)

Preceding gene: 116515043

Following gene: 116515045

Centisome position: 28.56

GC content: 23.96

Gene sequence:

>939_bases
ATGAAAGAGAAAATTTTTTTTGTTATTAAATTTTTATTTTTTATTATTTTTGGTGCGAGTTTTTTAAGTGTAATAGAACG
TAGAATATTAGGAATATTACAAAATCGATATGGTCCTAATAGAGTAGGTTGGCAAGGTTGTATGCAATTATTTGCAGATA
TGATAAAATTAATATTTAAAGAAGATTGGATACCTCCTTTTAGTGAAAAAATTTTATTTATTACTGCTCCTATTATTTCT
TTTATTTCTCTTTTATTAGTATTTTCTATTATTCCTATTACTTCAAAGTGTTTTATTATAAATTTAGATATTGGAATTTT
ATTTTTTATAATGATGTCTTCATTATCAGTGTACGGGGTTTTATTAGCAGGATGGTCAAGTAACAATAAATATGCTTTAT
TAGGATCTATTAGATCTGTCGCTCAAATGTTAAGTTATGAAATTTTTTTAGGATTATCAGCAATGGGTGCTGTTATGCAA
TGCGGATCTTTTAATTTAATTGATATTGTATATTCTCAAAAAAAAATTTGGAATATTTTTCCTCAATTTTTTGGTTTTAT
TTTATTTTTTATTGCTGGTATTGCTGTTTGTCATAGACATCCATTTGATCACCTGAGTCTGACAGAATTAGCAGATGGAT
ATCATATTGAATATTCAGGAATGAAATTTGGAATGTTTTTTATTGCTGAATATATTTCAATTATTACTGTTTCATCATTA
ATTGTATGTTTATTTTTTGGTGGTTGGTTAGGTCCTTTTTTTTCTCCTCTTTTTTGGTTCTTATTAAAAACTTTATTTTT
TATTTTTTTATTTATTTTGTTTCGAGCTTCATTACCTAGACCAAAATATGAACATGTTATGTTATTTGCATGGAAATTTT
TTTTTCCTTTATCATTATTAAATATAATTTATACATCTTTTAAAATTTTATTAAAATAG

Upstream 100 bases:

>100_bases
CTGTTGGTATTGGTAATATACCGATGATTTTTTTAAATAAAATTGCTATAAAATTAATGAAATATAATATATAAATGAGA
TATTTTAATTAGGTATATAC

Downstream 100 bases:

>100_bases
GAAATACATAAATTTATGAATATGAAAAATATATTTCTTGGTTTTTTAAGTCAAATTCGTAGTATATTAATGATTTTTAG
CAACATTTTTTCTTTTCGTG

Product: NADH dehydrogenase I chain H

Products: NA

Alternate protein names: NADH dehydrogenase I subunit H; NDH-1 subunit H [H]

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MKEKIFFVIKFLFFIIFGASFLSVIERRILGILQNRYGPNRVGWQGCMQLFADMIKLIFKEDWIPPFSEKILFITAPIIS
FISLLLVFSIIPITSKCFIINLDIGILFFIMMSSLSVYGVLLAGWSSNNKYALLGSIRSVAQMLSYEIFLGLSAMGAVMQ
CGSFNLIDIVYSQKKIWNIFPQFFGFILFFIAGIAVCHRHPFDHLSLTELADGYHIEYSGMKFGMFFIAEYISIITVSSL
IVCLFFGGWLGPFFSPLFWFLLKTLFFIFLFILFRASLPRPKYEHVMLFAWKFFFPLSLLNIIYTSFKILLK

Sequences:

>Translated_312_residues
MKEKIFFVIKFLFFIIFGASFLSVIERRILGILQNRYGPNRVGWQGCMQLFADMIKLIFKEDWIPPFSEKILFITAPIIS
FISLLLVFSIIPITSKCFIINLDIGILFFIMMSSLSVYGVLLAGWSSNNKYALLGSIRSVAQMLSYEIFLGLSAMGAVMQ
CGSFNLIDIVYSQKKIWNIFPQFFGFILFFIAGIAVCHRHPFDHLSLTELADGYHIEYSGMKFGMFFIAEYISIITVSSL
IVCLFFGGWLGPFFSPLFWFLLKTLFFIFLFILFRASLPRPKYEHVMLFAWKFFFPLSLLNIIYTSFKILLK
>Mature_312_residues
MKEKIFFVIKFLFFIIFGASFLSVIERRILGILQNRYGPNRVGWQGCMQLFADMIKLIFKEDWIPPFSEKILFITAPIIS
FISLLLVFSIIPITSKCFIINLDIGILFFIMMSSLSVYGVLLAGWSSNNKYALLGSIRSVAQMLSYEIFLGLSAMGAVMQ
CGSFNLIDIVYSQKKIWNIFPQFFGFILFFIAGIAVCHRHPFDHLSLTELADGYHIEYSGMKFGMFFIAEYISIITVSSL
IVCLFFGGWLGPFFSPLFWFLLKTLFFIFLFILFRASLPRPKYEHVMLFAWKFFFPLSLLNIIYTSFKILLK

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1005

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 1 (chain H)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 1 family [H]

Homologues:

Organism=Homo sapiens, GI251831107, Length=283, Percent_Identity=38.86925795053, Blast_Score=197, Evalue=1e-50,
Organism=Escherichia coli, GI1788618, Length=310, Percent_Identity=60.3225806451613, Blast_Score=402, Evalue=1e-113,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023020
- InterPro:   IPR001694
- InterPro:   IPR018086 [H]

Pfam domain/function: PF00146 NADHdh [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 36090; Mature: 36090

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEKIFFVIKFLFFIIFGASFLSVIERRILGILQNRYGPNRVGWQGCMQLFADMIKLIFK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
EDWIPPFSEKILFITAPIISFISLLLVFSIIPITSKCFIINLDIGILFFIMMSSLSVYGV
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHH
LLAGWSSNNKYALLGSIRSVAQMLSYEIFLGLSAMGAVMQCGSFNLIDIVYSQKKIWNIF
HHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
PQFFGFILFFIAGIAVCHRHPFDHLSLTELADGYHIEYSGMKFGMFFIAEYISIITVSSL
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHH
IVCLFFGGWLGPFFSPLFWFLLKTLFFIFLFILFRASLPRPKYEHVMLFAWKFFFPLSLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
NIIYTSFKILLK
HHHHHHHHHHCC
>Mature Secondary Structure
MKEKIFFVIKFLFFIIFGASFLSVIERRILGILQNRYGPNRVGWQGCMQLFADMIKLIFK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
EDWIPPFSEKILFITAPIISFISLLLVFSIIPITSKCFIINLDIGILFFIMMSSLSVYGV
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHH
LLAGWSSNNKYALLGSIRSVAQMLSYEIFLGLSAMGAVMQCGSFNLIDIVYSQKKIWNIF
HHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
PQFFGFILFFIAGIAVCHRHPFDHLSLTELADGYHIEYSGMKFGMFFIAEYISIITVSSL
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHH
IVCLFFGGWLGPFFSPLFWFLLKTLFFIFLFILFRASLPRPKYEHVMLFAWKFFFPLSLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
NIIYTSFKILLK
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12522265 [H]