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The map label for this gene is nuoE [H]

Identifier: 116515041

GI number: 116515041

Start: 114234

End: 114704

Strand: Direct

Name: nuoE [H]

Synonym: BCc_100

Alternate gene names: 116515041

Gene position: 114234-114704 (Clockwise)

Preceding gene: 116515040

Following gene: 116515042

Centisome position: 27.44

GC content: 23.99

Gene sequence:

>471_bases
GTGTTTGAATTAAGTAAATTAGAGATTTCTAAAATTTTAAAAAAAAAAAAATGTTATGTTAATTCACAAGCAGCGTGTAT
TGAAGCTTTAAAAATTGTACAAGAACATAGAAAGTGGATTTGTAAAGACTCTATTATAGCAATTTCTAAAATATTATCTA
TTCCAGCATGTGAAGTAGAAAGTATAGCAACTTTTTATTGTCATATTTTTCGGAAACCAGTAGGTCGTAATATAATTCGT
TATTGTGATAGTGTTGTATGTTTTATTAATAATTTTAAAAGTATTAAAAAAAAATTAAAATATATTTTAAATATTTCTCC
AGGAGAAACAACTTCTGATTGTAGATATACTTTGTTACCAACCTGTTGTTTAGGAGCTTGTGATAAAGGTCCTGTAATGC
TAGTTAATAAAACTTTATATACTAGACTTACTTCAAAAATGTTAATTAATATATTGGATAAATATAAATGA

Upstream 100 bases:

>100_bases
TATGTAATATCAGATTTGATTGTTTATTTAGGTAGTATTGATTTTGTGATGTCAGATGTAGATAGATAAATTTATTTGTA
TAAAAATTAGGAAAAATAAA

Downstream 100 bases:

>100_bases
TATATATGTTAAAAACATCTGAAACTCATCCTTTAACATGGAGAATAGATAAATATTCTTCTAATAAATCTATTGGAATA
CATGAGTACTGTCACACTGG

Product: NADH dehydrogenase I chain E

Products: NA

Alternate protein names: NADH dehydrogenase I subunit E; NDH-1 subunit E; NUO5 [H]

Number of amino acids: Translated: 156; Mature: 156

Protein sequence:

>156_residues
MFELSKLEISKILKKKKCYVNSQAACIEALKIVQEHRKWICKDSIIAISKILSIPACEVESIATFYCHIFRKPVGRNIIR
YCDSVVCFINNFKSIKKKLKYILNISPGETTSDCRYTLLPTCCLGACDKGPVMLVNKTLYTRLTSKMLINILDKYK

Sequences:

>Translated_156_residues
MFELSKLEISKILKKKKCYVNSQAACIEALKIVQEHRKWICKDSIIAISKILSIPACEVESIATFYCHIFRKPVGRNIIR
YCDSVVCFINNFKSIKKKLKYILNISPGETTSDCRYTLLPTCCLGACDKGPVMLVNKTLYTRLTSKMLINILDKYK
>Mature_156_residues
MFELSKLEISKILKKKKCYVNSQAACIEALKIVQEHRKWICKDSIIAISKILSIPACEVESIATFYCHIFRKPVGRNIIR
YCDSVVCFINNFKSIKKKLKYILNISPGETTSDCRYTLLPTCCLGACDKGPVMLVNKTLYTRLTSKMLINILDKYK

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1905

COG function: function code C; NADH:ubiquinone oxidoreductase 24 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 24 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI222080062, Length=133, Percent_Identity=34.5864661654135, Blast_Score=91, Evalue=4e-19,
Organism=Escherichia coli, GI1788621, Length=155, Percent_Identity=52.258064516129, Blast_Score=183, Evalue=4e-48,
Organism=Caenorhabditis elegans, GI17561328, Length=133, Percent_Identity=32.3308270676692, Blast_Score=87, Evalue=2e-18,
Organism=Drosophila melanogaster, GI21355353, Length=153, Percent_Identity=31.3725490196078, Blast_Score=87, Evalue=6e-18,
Organism=Drosophila melanogaster, GI18859877, Length=134, Percent_Identity=32.8358208955224, Blast_Score=85, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002023
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01257 Complex1_24kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 17867; Mature: 17867

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

7.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
9.0 %Cys+Met (Translated Protein)
7.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
9.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFELSKLEISKILKKKKCYVNSQAACIEALKIVQEHRKWICKDSIIAISKILSIPACEVE
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
SIATFYCHIFRKPVGRNIIRYCDSVVCFINNFKSIKKKLKYILNISPGETTSDCRYTLLP
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
TCCLGACDKGPVMLVNKTLYTRLTSKMLINILDKYK
HHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFELSKLEISKILKKKKCYVNSQAACIEALKIVQEHRKWICKDSIIAISKILSIPACEVE
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
SIATFYCHIFRKPVGRNIIRYCDSVVCFINNFKSIKKKLKYILNISPGETTSDCRYTLLP
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
TCCLGACDKGPVMLVNKTLYTRLTSKMLINILDKYK
HHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]