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The map label for this gene is 116332547

Identifier: 116332547

GI number: 116332547

Start: 129840

End: 131258

Strand: Direct

Name: 116332547

Synonym: LBJ_4113

Alternate gene names: NA

Gene position: 129840-131258 (Clockwise)

Preceding gene: 116332546

Following gene: 116332548

Centisome position: 43.31

GC content: 40.94

Gene sequence:

>1419_bases
ATGGATTCGATGAAATTAAAGGTGGATGAGCTCATCCAAAAAAAAATGGCTGCGGAAGGTTTGTCCCCCGCTTTCATCCA
GGACTTTTTGAAAAAAACGGATCTGGTTCGAAATGGAGAAACTGGAATTGTTCGTTGGGAAGAAGTAGGCGATCTGGATC
CGGTTACGGACGAGATCTCTCTCGAACAAATCGAAAAAGAAAATGCTCCGAATCCGTCGATCCTTAGAAATCTGGTTATT
ATCAAACTGAACGGAGGACTCGGAACTTCGATGGGGCTTTCCGGTCCTAAATCTTTGATTGAACTGAAAGACGGAATGTC
TTTTTTAGAAATCGTCGCCAAACAATCCGAATTCATTCAAAAGAAATATAACGTGTCTGTTCCTTTGATTCTGATGGACA
GTTTCAATACACAAAGTGAAAGTCAGACGGAACTGAAAAGAATCGGGTTCCGACAAAAATTCCCGACTTCTTTCTTACAG
CATAAAGTACCTCGTCTTTTAAAAGAGAATCTAACGCCGATTGTGTGCAAAAATCCTGACGACGAATGGTGTCCTCCAGG
CCACGGAGATATTTGGATTTCTCTTTTGGAGACGGGATTTTTGGACACCCTCATTGCAAATGGATATAAAGTTGCGTTCG
TATCTAACGGAGATAATTTAGGAGCTACGGTACATCCCGGAATTCTTTCTTATATGTTGAAAGAAAAATTGGAATTCTGT
ATGGAAATGACTCCGAAGACTCTTGCCGATAAAAAAGGCGGGGCGATCTACAAAAGAATCGTTCATGGAAAACTGGAGAA
TTACCAACTTCTCGAAACGGCTCAAGTACCTCAAGAACACATACACGAATTTGAAGGTTTGGGCAAATTTAGAACTTTTT
CGACCAACAACCTCTGGATCAATTTAATTGTTCTTCGGGAAAAAATTCTTCAAGGTAATTTTGAACTTTCTCTGATCGTA
AATCCGAAAATAATTGAAGGAAAAGACGTTCTTCAGCTTGAAACCGCAATGGGATCTGCGATTCGAAATTTTAATAAGAT
CAAGGGGATCATTATTCCCAGGGATCGATTTACTCCTGTAAAAAAATGTGAGGATTATCTTGCCCGAAGATCCGACGCGT
ATTGTCTTTGGGAAAACTACTCAATGACGATGTCCGACGCAAGGAAGGAATCGGGGTTAGGCGAAGTATTGATTACTTTG
GATGAAAAATACTACAAGAAAATCCAAGACTTCAATCGACTTTTTCCGGAGATCCCTTCTTTGGTGCGTTGCGCTTCTCT
CATCGTTCAGGGAGAAGTACTATTCGATCAAAAAGTCTCGATCATAGGTGACGTAGTGATCCAGAACACCGGTTCCGGGC
TTCGTAAAATATCGGACTTGGGATCGGGAGTTTTAGAGTCCGGAAAATATTCCTTTTAA

Upstream 100 bases:

>100_bases
TAAGAGTAAAGCTTTTTTATGAACCTTCGAACCCATCCGAGAAATTCTTGATTGAGTTTACCGAGTTCGACGAACGATAC
AATAGCAGATCGGTGGTTCG

Downstream 100 bases:

>100_bases
GGCTTTACAAAGAGGATCTCTTATTGGAATTATTGGAACGAATCGGTGTTCAGATTTTAGACTGACGGATTTTTTGAATA
AGATTACAATGACAACTTCT

Product: nucleotide glucose-1-phosphate uridylyl transferase

Products: diphosphate; UDP-glucose

Alternate protein names: UDP-Glucose Pyrophosphorylase; UTP-Glucose-1-Phosphate Uridyltransferase; Nucleotide Glucose-1-Phosphate Uridylyl Transferase; Glucose-1-Phosphate Uridylyltransferase; Molybdenum Cofactor Synthesis Domain Protein

Number of amino acids: Translated: 472; Mature: 472

Protein sequence:

>472_residues
MDSMKLKVDELIQKKMAAEGLSPAFIQDFLKKTDLVRNGETGIVRWEEVGDLDPVTDEISLEQIEKENAPNPSILRNLVI
IKLNGGLGTSMGLSGPKSLIELKDGMSFLEIVAKQSEFIQKKYNVSVPLILMDSFNTQSESQTELKRIGFRQKFPTSFLQ
HKVPRLLKENLTPIVCKNPDDEWCPPGHGDIWISLLETGFLDTLIANGYKVAFVSNGDNLGATVHPGILSYMLKEKLEFC
MEMTPKTLADKKGGAIYKRIVHGKLENYQLLETAQVPQEHIHEFEGLGKFRTFSTNNLWINLIVLREKILQGNFELSLIV
NPKIIEGKDVLQLETAMGSAIRNFNKIKGIIIPRDRFTPVKKCEDYLARRSDAYCLWENYSMTMSDARKESGLGEVLITL
DEKYYKKIQDFNRLFPEIPSLVRCASLIVQGEVLFDQKVSIIGDVVIQNTGSGLRKISDLGSGVLESGKYSF

Sequences:

>Translated_472_residues
MDSMKLKVDELIQKKMAAEGLSPAFIQDFLKKTDLVRNGETGIVRWEEVGDLDPVTDEISLEQIEKENAPNPSILRNLVI
IKLNGGLGTSMGLSGPKSLIELKDGMSFLEIVAKQSEFIQKKYNVSVPLILMDSFNTQSESQTELKRIGFRQKFPTSFLQ
HKVPRLLKENLTPIVCKNPDDEWCPPGHGDIWISLLETGFLDTLIANGYKVAFVSNGDNLGATVHPGILSYMLKEKLEFC
MEMTPKTLADKKGGAIYKRIVHGKLENYQLLETAQVPQEHIHEFEGLGKFRTFSTNNLWINLIVLREKILQGNFELSLIV
NPKIIEGKDVLQLETAMGSAIRNFNKIKGIIIPRDRFTPVKKCEDYLARRSDAYCLWENYSMTMSDARKESGLGEVLITL
DEKYYKKIQDFNRLFPEIPSLVRCASLIVQGEVLFDQKVSIIGDVVIQNTGSGLRKISDLGSGVLESGKYSF
>Mature_472_residues
MDSMKLKVDELIQKKMAAEGLSPAFIQDFLKKTDLVRNGETGIVRWEEVGDLDPVTDEISLEQIEKENAPNPSILRNLVI
IKLNGGLGTSMGLSGPKSLIELKDGMSFLEIVAKQSEFIQKKYNVSVPLILMDSFNTQSESQTELKRIGFRQKFPTSFLQ
HKVPRLLKENLTPIVCKNPDDEWCPPGHGDIWISLLETGFLDTLIANGYKVAFVSNGDNLGATVHPGILSYMLKEKLEFC
MEMTPKTLADKKGGAIYKRIVHGKLENYQLLETAQVPQEHIHEFEGLGKFRTFSTNNLWINLIVLREKILQGNFELSLIV
NPKIIEGKDVLQLETAMGSAIRNFNKIKGIIIPRDRFTPVKKCEDYLARRSDAYCLWENYSMTMSDARKESGLGEVLITL
DEKYYKKIQDFNRLFPEIPSLVRCASLIVQGEVLFDQKVSIIGDVVIQNTGSGLRKISDLGSGVLESGKYSF

Specific function: Unknown

COG id: COG4284

COG function: function code G; UDP-glucose pyrophosphorylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI48255966, Length=407, Percent_Identity=41.2776412776413, Blast_Score=285, Evalue=9e-77,
Organism=Homo sapiens, GI48255968, Length=407, Percent_Identity=41.2776412776413, Blast_Score=284, Evalue=1e-76,
Organism=Caenorhabditis elegans, GI71988370, Length=384, Percent_Identity=42.1875, Blast_Score=280, Evalue=1e-75,
Organism=Caenorhabditis elegans, GI17554114, Length=384, Percent_Identity=42.1875, Blast_Score=280, Evalue=1e-75,
Organism=Caenorhabditis elegans, GI17554112, Length=384, Percent_Identity=42.1875, Blast_Score=280, Evalue=1e-75,
Organism=Caenorhabditis elegans, GI71988365, Length=384, Percent_Identity=42.1875, Blast_Score=280, Evalue=1e-75,
Organism=Caenorhabditis elegans, GI17554108, Length=384, Percent_Identity=42.1875, Blast_Score=280, Evalue=2e-75,
Organism=Caenorhabditis elegans, GI17554110, Length=370, Percent_Identity=41.0810810810811, Blast_Score=261, Evalue=8e-70,
Organism=Caenorhabditis elegans, GI25151022, Length=396, Percent_Identity=36.1111111111111, Blast_Score=238, Evalue=5e-63,
Organism=Saccharomyces cerevisiae, GI6322815, Length=419, Percent_Identity=41.2887828162291, Blast_Score=308, Evalue=1e-84,
Organism=Saccharomyces cerevisiae, GI6321775, Length=407, Percent_Identity=30.2211302211302, Blast_Score=154, Evalue=4e-38,
Organism=Drosophila melanogaster, GI62484452, Length=417, Percent_Identity=39.0887290167866, Blast_Score=266, Evalue=3e-71,
Organism=Drosophila melanogaster, GI62484278, Length=417, Percent_Identity=39.0887290167866, Blast_Score=266, Evalue=3e-71,
Organism=Drosophila melanogaster, GI281365931, Length=388, Percent_Identity=40.7216494845361, Blast_Score=266, Evalue=3e-71,
Organism=Drosophila melanogaster, GI281365929, Length=388, Percent_Identity=40.7216494845361, Blast_Score=266, Evalue=3e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.7.7.9

Molecular weight: Translated: 53143; Mature: 53143

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSMKLKVDELIQKKMAAEGLSPAFIQDFLKKTDLVRNGETGIVRWEEVGDLDPVTDEIS
CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEEHHCCCCCCCCCHHH
LEQIEKENAPNPSILRNLVIIKLNGGLGTSMGLSGPKSLIELKDGMSFLEIVAKQSEFIQ
HHHHHHCCCCCHHHHHCEEEEEECCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHH
KKYNVSVPLILMDSFNTQSESQTELKRIGFRQKFPTSFLQHKVPRLLKENLTPIVCKNPD
HHHCCCCEEEEEECCCCCCHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHCCCEEEECCCC
DEWCPPGHGDIWISLLETGFLDTLIANGYKVAFVSNGDNLGATVHPGILSYMLKEKLEFC
CCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCEECHHHHHHHHHHHHHHH
MEMTPKTLADKKGGAIYKRIVHGKLENYQLLETAQVPQEHIHEFEGLGKFRTFSTNNLWI
HHCCCHHHHCCCCCHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHCCCCEEEEECCCEEE
NLIVLREKILQGNFELSLIVNPKIIEGKDVLQLETAMGSAIRNFNKIKGIIIPRDRFTPV
EHHHHHHHHHCCCCEEEEEECCEEECCCCHHHHHHHHHHHHHHHHHHCCEEECCCCCCHH
KKCEDYLARRSDAYCLWENYSMTMSDARKESGLGEVLITLDEKYYKKIQDFNRLFPEIPS
HHHHHHHHCCCCCEEEEECCCCCHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHH
LVRCASLIVQGEVLFDQKVSIIGDVVIQNTGSGLRKISDLGSGVLESGKYSF
HHHHHHHHHCCHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MDSMKLKVDELIQKKMAAEGLSPAFIQDFLKKTDLVRNGETGIVRWEEVGDLDPVTDEIS
CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEEHHCCCCCCCCCHHH
LEQIEKENAPNPSILRNLVIIKLNGGLGTSMGLSGPKSLIELKDGMSFLEIVAKQSEFIQ
HHHHHHCCCCCHHHHHCEEEEEECCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHH
KKYNVSVPLILMDSFNTQSESQTELKRIGFRQKFPTSFLQHKVPRLLKENLTPIVCKNPD
HHHCCCCEEEEEECCCCCCHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHCCCEEEECCCC
DEWCPPGHGDIWISLLETGFLDTLIANGYKVAFVSNGDNLGATVHPGILSYMLKEKLEFC
CCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCEECHHHHHHHHHHHHHHH
MEMTPKTLADKKGGAIYKRIVHGKLENYQLLETAQVPQEHIHEFEGLGKFRTFSTNNLWI
HHCCCHHHHCCCCCHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHCCCCEEEEECCCEEE
NLIVLREKILQGNFELSLIVNPKIIEGKDVLQLETAMGSAIRNFNKIKGIIIPRDRFTPV
EHHHHHHHHHCCCCEEEEEECCEEECCCCHHHHHHHHHHHHHHHHHHCCEEECCCCCCHH
KKCEDYLARRSDAYCLWENYSMTMSDARKESGLGEVLITLDEKYYKKIQDFNRLFPEIPS
HHHHHHHHCCCCCEEEEECCCCCHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHH
LVRCASLIVQGEVLFDQKVSIIGDVVIQNTGSGLRKISDLGSGVLESGKYSF
HHHHHHHHHCCHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: UTP; alpha-D-glucose 1-phosphate

Specific reaction: UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA