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The map label for this gene is rfbB [C]

Identifier: 116327928

GI number: 116327928

Start: 1429852

End: 1430850

Strand: Direct

Name: rfbB [C]

Synonym: LBL_1214

Alternate gene names: 116327928

Gene position: 1429852-1430850 (Clockwise)

Preceding gene: 116327927

Following gene: 116327929

Centisome position: 39.56

GC content: 41.94

Gene sequence:

>999_bases
TTGAAAAAAATTTTAGTTACCGGTGCAGATGGTTTTATAGGTTCGCATCTTACAGAGGCTTTGGTTAGATTGGGGTTCGA
GGTCAAAGCTTTCGTTTATTATAATTCTTTTAACACTTGGGGGTGGTTGGATTATTGTTCCAGCGACGTCAGGGGTAAAT
TTGAAATTTTTACGGGTGACGTTCGCGACCCAAACGGAGTCAGAACTGCTATGAAGGGAATTGACGCTGTTCTGCACTTG
GCAGCTCTTATTGGTATTCCTTATTCCTATCATTCTCCGGATACGTATGTCGACACGAATATTAAAGGAACGTTGAATGT
TCTGCAAGCGGCAAGGGATCTGAATTTAAGCAGAGTCATTCATACTTCTACGAGCGAAGTTTATGGTACTGCCCAGTTTG
TTCCCATTACGGAAGAACATCCTCTGAAGGGACAGTCTCCGTATTCCGCAAGTAAAATCGGTGCCGATCAACTGGCCTAT
TCGTTTTATTCCTCTTTTTCAACACCAGTCATCATCGTTCGACCATTCAATACATACGGTCCCAGGCAGTCGGCAAGGGC
GATCATTCCGACGGTTATTACTCAGTTGCTCAGTGGAAAAACAAAGATTCAATTGGGTTCTACGAGTCCGACCCGTGATT
TTAACTTTGTAACGGACACTGTGAACGGTTTTATTAGTGCCTTAAAATCCAAACAAGGTTTGGGAGAGGTGATCAATATT
GGAAATGGATTTGAAATTTCTGTTGGAGATACAGTGAAGCTGATCGCAAGTATCTTAGATAAGGAAGTTGAAATCGTATC
CGATGTTAATCGAATAAGACCCGAAAAAAGTGAAGTGGAGAGGCTCTGGTCTTCCAATCAGAAAGCGAAAGATTTGTTTG
GTTGGCAACCGGCCTACAGTGGGTTAGAAGGATTTAAACGCGGTCTTACTGAAACTATTGAGTGGTTTCGATATCCTGAA
AACTTAAAGAGTTATAAGGCAGAAGTCTACAATGTCTAA

Upstream 100 bases:

>100_bases
TGGCATTTATACTTCCAACCTTAAGAATGTGATCGGTTTGTGATCCGTTTTTTAAATCCAAATTTACATTCATTCATAAA
TAAAACGAAGAGGTCCTCCT

Downstream 100 bases:

>100_bases
ACGCGCGGTTATTCTAGCAGGTGGTAAAGGGACACGATTACGTCCTTATACTACTGTATTTCCTAAGCCATTGATGCCTA
TTGGAGAATACCCTATCCTA

Product: nucleoside-diphosphate-sugar epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MKKILVTGADGFIGSHLTEALVRLGFEVKAFVYYNSFNTWGWLDYCSSDVRGKFEIFTGDVRDPNGVRTAMKGIDAVLHL
AALIGIPYSYHSPDTYVDTNIKGTLNVLQAARDLNLSRVIHTSTSEVYGTAQFVPITEEHPLKGQSPYSASKIGADQLAY
SFYSSFSTPVIIVRPFNTYGPRQSARAIIPTVITQLLSGKTKIQLGSTSPTRDFNFVTDTVNGFISALKSKQGLGEVINI
GNGFEISVGDTVKLIASILDKEVEIVSDVNRIRPEKSEVERLWSSNQKAKDLFGWQPAYSGLEGFKRGLTETIEWFRYPE
NLKSYKAEVYNV

Sequences:

>Translated_332_residues
MKKILVTGADGFIGSHLTEALVRLGFEVKAFVYYNSFNTWGWLDYCSSDVRGKFEIFTGDVRDPNGVRTAMKGIDAVLHL
AALIGIPYSYHSPDTYVDTNIKGTLNVLQAARDLNLSRVIHTSTSEVYGTAQFVPITEEHPLKGQSPYSASKIGADQLAY
SFYSSFSTPVIIVRPFNTYGPRQSARAIIPTVITQLLSGKTKIQLGSTSPTRDFNFVTDTVNGFISALKSKQGLGEVINI
GNGFEISVGDTVKLIASILDKEVEIVSDVNRIRPEKSEVERLWSSNQKAKDLFGWQPAYSGLEGFKRGLTETIEWFRYPE
NLKSYKAEVYNV
>Mature_332_residues
MKKILVTGADGFIGSHLTEALVRLGFEVKAFVYYNSFNTWGWLDYCSSDVRGKFEIFTGDVRDPNGVRTAMKGIDAVLHL
AALIGIPYSYHSPDTYVDTNIKGTLNVLQAARDLNLSRVIHTSTSEVYGTAQFVPITEEHPLKGQSPYSASKIGADQLAY
SFYSSFSTPVIIVRPFNTYGPRQSARAIIPTVITQLLSGKTKIQLGSTSPTRDFNFVTDTVNGFISALKSKQGLGEVINI
GNGFEISVGDTVKLIASILDKEVEIVSDVNRIRPEKSEVERLWSSNQKAKDLFGWQPAYSGLEGFKRGLTETIEWFRYPE
NLKSYKAEVYNV

Specific function: DTDP-L-RHAMNOSE BIOSYNTHESIS WITHIN THE O ANTIGEN BIOSYNTHESIS PATHWAY OF LIPOPOLYSACCHARIDE BIOSYNTHESIS. [C]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI7657641, Length=337, Percent_Identity=31.1572700296736, Blast_Score=149, Evalue=4e-36,
Organism=Homo sapiens, GI42516563, Length=328, Percent_Identity=29.2682926829268, Blast_Score=136, Evalue=3e-32,
Organism=Homo sapiens, GI56237023, Length=343, Percent_Identity=25.0728862973761, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI56118217, Length=343, Percent_Identity=25.0728862973761, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI189083684, Length=343, Percent_Identity=25.0728862973761, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI4504031, Length=344, Percent_Identity=25, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI193211614, Length=363, Percent_Identity=24.2424242424242, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI8393516, Length=363, Percent_Identity=24.2424242424242, Blast_Score=79, Evalue=7e-15,
Organism=Escherichia coli, GI1788353, Length=355, Percent_Identity=30.9859154929577, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI48994969, Length=346, Percent_Identity=28.6127167630058, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1788366, Length=372, Percent_Identity=27.1505376344086, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1786974, Length=319, Percent_Identity=26.3322884012539, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1788365, Length=273, Percent_Identity=23.8095238095238, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17539532, Length=326, Percent_Identity=28.5276073619632, Blast_Score=121, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI17568069, Length=327, Percent_Identity=26.2996941896024, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI115532424, Length=330, Percent_Identity=24.5454545454545, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17539424, Length=328, Percent_Identity=28.0487804878049, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI133901788, Length=328, Percent_Identity=28.0487804878049, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI133901786, Length=328, Percent_Identity=28.0487804878049, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17539422, Length=328, Percent_Identity=28.0487804878049, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI133901790, Length=328, Percent_Identity=28.0487804878049, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17507723, Length=329, Percent_Identity=26.1398176291793, Blast_Score=85, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI71982038, Length=337, Percent_Identity=26.4094955489614, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71982035, Length=336, Percent_Identity=25.5952380952381, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71987463, Length=253, Percent_Identity=26.0869565217391, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319493, Length=339, Percent_Identity=25.9587020648968, Blast_Score=87, Evalue=3e-18,
Organism=Drosophila melanogaster, GI21356223, Length=326, Percent_Identity=29.7546012269939, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI19923002, Length=342, Percent_Identity=26.0233918128655, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24158427, Length=347, Percent_Identity=23.9193083573487, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36823; Mature: 36823

Theoretical pI: Translated: 8.33; Mature: 8.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKILVTGADGFIGSHLTEALVRLGFEVKAFVYYNSFNTWGWLDYCSSDVRGKFEIFTGD
CCEEEEECCCCHHHHHHHHHHHHCCCEEEEEEEEECCCCCCHHHHHCCCCCCEEEEEECC
VRDPNGVRTAMKGIDAVLHLAALIGIPYSYHSPDTYVDTNIKGTLNVLQAARDLNLSRVI
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCHHHHHHHHHHCCCHHHEE
HTSTSEVYGTAQFVPITEEHPLKGQSPYSASKIGADQLAYSFYSSFSTPVIIVRPFNTYG
ECCCHHHCCCEEEEECCCCCCCCCCCCCCHHHCCHHHHHHHHHHCCCCCEEEEECCCCCC
PRQSARAIIPTVITQLLSGKTKIQLGSTSPTRDFNFVTDTVNGFISALKSKQGLGEVINI
CCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHCC
GNGFEISVGDTVKLIASILDKEVEIVSDVNRIRPEKSEVERLWSSNQKAKDLFGWQPAYS
CCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHCCCCHHHH
GLEGFKRGLTETIEWFRYPENLKSYKAEVYNV
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKILVTGADGFIGSHLTEALVRLGFEVKAFVYYNSFNTWGWLDYCSSDVRGKFEIFTGD
CCEEEEECCCCHHHHHHHHHHHHCCCEEEEEEEEECCCCCCHHHHHCCCCCCEEEEEECC
VRDPNGVRTAMKGIDAVLHLAALIGIPYSYHSPDTYVDTNIKGTLNVLQAARDLNLSRVI
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCHHHHHHHHHHCCCHHHEE
HTSTSEVYGTAQFVPITEEHPLKGQSPYSASKIGADQLAYSFYSSFSTPVIIVRPFNTYG
ECCCHHHCCCEEEEECCCCCCCCCCCCCCHHHCCHHHHHHHHHHCCCCCEEEEECCCCCC
PRQSARAIIPTVITQLLSGKTKIQLGSTSPTRDFNFVTDTVNGFISALKSKQGLGEVINI
CCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHCC
GNGFEISVGDTVKLIASILDKEVEIVSDVNRIRPEKSEVERLWSSNQKAKDLFGWQPAYS
CCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHCCCCHHHH
GLEGFKRGLTETIEWFRYPENLKSYKAEVYNV
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]