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The map label for this gene is kdsB-2 [H]

Identifier: 116327912

GI number: 116327912

Start: 1412906

End: 1413661

Strand: Direct

Name: kdsB-2 [H]

Synonym: LBL_1198

Alternate gene names: 116327912

Gene position: 1412906-1413661 (Clockwise)

Preceding gene: 116327911

Following gene: 116327913

Centisome position: 39.09

GC content: 40.08

Gene sequence:

>756_bases
ATGAAAACGATTGCTGTGTTGCCGGCGAGAATGGCATCTTCCAGATTTCCCGATAAACCATTGGTTAAGATCTCTGGATT
AGAAATGATAGAACACGTGAGACGTAGAGTAGAAATGTCTTCTTCTGTAGACAAGGTGGTTGTAGCCACTTGTGATGAAA
TCATTAAACAAAGAATAGAATCTTTTGGTGGAAAAGCGGTGATGACTTCGGATGTTCACAGGGGTTGTATTGACCGGGTT
GCAGAGGCAGCTCTCTACATAAAAGGAGATATCGTTATTGTCGTCCAAGGAGACGAGCCCTTGATTTTACCAGCTATGTT
GGATGATTTGGTCAAACCGATATTAAACGACTCTTCAATTTATTGTACAAATTTAGTTACAAAGATTGTAGATGAAGAAG
AGTTTCAAAGTCCAAACGCTCCTAAGGTCGTTGTTGATAAAAATTGGGACTTGCTTTATGCTTCGAGAGAACCAATTCCG
TCTCGAAAAAAATATCCAAATGAGGATTATTTAAAACTCAAGCAACTAGGAGTGATTGCATTTCGAAACGATTTCTTACA
AACATTTGCAGCTCTTGCCCCGACCCCTTTAGAGATTATCGAATCGGTGGATATGAATCGTGCAATTGAGCACGGCTATA
AAGTACGAATGGTGCTAACAGAAGGGGTGATGATTGGAGTGGACGTTCCAGGAGACGTTTCCAGAGTAGAGTCTGTTTTT
AAAACGGACTTGTTACTATCGAAGTATTTATCATGA

Upstream 100 bases:

>100_bases
CTATTCTACGGATGCGATTATGTTAAATACGCAAGCTAATTTGAATTTTGAAGAATTAATATAATTTAAAGTTATTAATT
ACTAATTTTGGAATAAAAAT

Downstream 100 bases:

>100_bases
GTATGAAGAAGCTTAAAGTTGGAATTGCAGGATATGGGGTCGTAGGAAAACGCAGACATCAATATATCAAACAAAACCCT
AATTTAATGGTTACCGCAAT

Product: 3-deoxy-manno-octulosonate cytidylyltransferase

Products: NA

Alternate protein names: CMP-2-keto-3-deoxyoctulosonic acid synthase; CKS; CMP-KDO synthase [H]

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MKTIAVLPARMASSRFPDKPLVKISGLEMIEHVRRRVEMSSSVDKVVVATCDEIIKQRIESFGGKAVMTSDVHRGCIDRV
AEAALYIKGDIVIVVQGDEPLILPAMLDDLVKPILNDSSIYCTNLVTKIVDEEEFQSPNAPKVVVDKNWDLLYASREPIP
SRKKYPNEDYLKLKQLGVIAFRNDFLQTFAALAPTPLEIIESVDMNRAIEHGYKVRMVLTEGVMIGVDVPGDVSRVESVF
KTDLLLSKYLS

Sequences:

>Translated_251_residues
MKTIAVLPARMASSRFPDKPLVKISGLEMIEHVRRRVEMSSSVDKVVVATCDEIIKQRIESFGGKAVMTSDVHRGCIDRV
AEAALYIKGDIVIVVQGDEPLILPAMLDDLVKPILNDSSIYCTNLVTKIVDEEEFQSPNAPKVVVDKNWDLLYASREPIP
SRKKYPNEDYLKLKQLGVIAFRNDFLQTFAALAPTPLEIIESVDMNRAIEHGYKVRMVLTEGVMIGVDVPGDVSRVESVF
KTDLLLSKYLS
>Mature_251_residues
MKTIAVLPARMASSRFPDKPLVKISGLEMIEHVRRRVEMSSSVDKVVVATCDEIIKQRIESFGGKAVMTSDVHRGCIDRV
AEAALYIKGDIVIVVQGDEPLILPAMLDDLVKPILNDSSIYCTNLVTKIVDEEEFQSPNAPKVVVDKNWDLLYASREPIP
SRKKYPNEDYLKLKQLGVIAFRNDFLQTFAALAPTPLEIIESVDMNRAIEHGYKVRMVLTEGVMIGVDVPGDVSRVESVF
KTDLLLSKYLS

Specific function: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria [H]

COG id: COG1212

COG function: function code M; CMP-2-keto-3-deoxyoctulosonic acid synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsB family [H]

Homologues:

Organism=Escherichia coli, GI1787147, Length=247, Percent_Identity=35.6275303643725, Blast_Score=128, Evalue=4e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003329
- InterPro:   IPR004528 [H]

Pfam domain/function: PF02348 CTP_transf_3 [H]

EC number: =2.7.7.38 [H]

Molecular weight: Translated: 28035; Mature: 28035

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTIAVLPARMASSRFPDKPLVKISGLEMIEHVRRRVEMSSSVDKVVVATCDEIIKQRIE
CCCEEECHHHHHHCCCCCCCCEEECHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
SFGGKAVMTSDVHRGCIDRVAEAALYIKGDIVIVVQGDEPLILPAMLDDLVKPILNDSSI
HCCCCEEEHHHHHHHHHHHHHHHHEEEECCEEEEEECCCCEEHHHHHHHHHHHHHCCCCC
YCTNLVTKIVDEEEFQSPNAPKVVVDKNWDLLYASREPIPSRKKYPNEDYLKLKQLGVIA
HHHHHHHHHHCHHHHCCCCCCEEEEECCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHH
FRNDFLQTFAALAPTPLEIIESVDMNRAIEHGYKVRMVLTEGVMIGVDVPGDVSRVESVF
HHHHHHHHHHHHCCCHHHHHHHCCHHHHHHCCCEEEEEEECCEEEEEECCCCHHHHHHHH
KTDLLLSKYLS
HHHHHHHHHCC
>Mature Secondary Structure
MKTIAVLPARMASSRFPDKPLVKISGLEMIEHVRRRVEMSSSVDKVVVATCDEIIKQRIE
CCCEEECHHHHHHCCCCCCCCEEECHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
SFGGKAVMTSDVHRGCIDRVAEAALYIKGDIVIVVQGDEPLILPAMLDDLVKPILNDSSI
HCCCCEEEHHHHHHHHHHHHHHHHEEEECCEEEEEECCCCEEHHHHHHHHHHHHHCCCCC
YCTNLVTKIVDEEEFQSPNAPKVVVDKNWDLLYASREPIPSRKKYPNEDYLKLKQLGVIA
HHHHHHHHHHCHHHHCCCCCCEEEEECCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHH
FRNDFLQTFAALAPTPLEIIESVDMNRAIEHGYKVRMVLTEGVMIGVDVPGDVSRVESVF
HHHHHHHHHHHHCCCHHHHHHHCCHHHHHHCCCEEEEEEECCEEEEEECCCCHHHHHHHH
KTDLLLSKYLS
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA