Click here to switch to the map view.

The map label for this gene is infA

Identifier: 116327286

GI number: 116327286

Start: 525096

End: 525314

Strand: Direct

Name: infA

Synonym: LBL_0475

Alternate gene names: 116327286

Gene position: 525096-525314 (Clockwise)

Preceding gene: 116327285

Following gene: 116327287

Centisome position: 14.53

GC content: 47.03

Gene sequence:

>219_bases
GTGGCAAAGGAAGAAGCGATCACAGTCGATGGTACCGTACTGGAGCCTCTGCCCAACGCGATGTTCCGAGTAGAACTGGA
AAACGGTCATAAGGTGTTGGCCCATATTTCCGGAAAGATGAGAATGCATTATATCCGGATTTTACCGGGTGATAAAGTTA
CGGTGGAACTCTCCCCTTATGATCTTTCTAAGGGCAGAATCACTTACCGCAAAAAGTAG

Upstream 100 bases:

>100_bases
TTTTGGATTTTTACGCGGCACAAAAGAAACTTTCTCAAGTGAATGGCGTCGGAACCCTCGAAGAAGTAACTTCTTTGATT
CAAAGGGAGCTTGTGTAAGA

Downstream 100 bases:

>100_bases
GAATTGTTATGAAAGTAAGAACATCAGTTAAGAAAATCTGCTCTAGCTGCAAGGTTATCAGAAGAAAAGGTGTGATTCGA
GTGATTTGCACCAATCCGAA

Product: translation initiation factor IF-1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 72; Mature: 71

Protein sequence:

>72_residues
MAKEEAITVDGTVLEPLPNAMFRVELENGHKVLAHISGKMRMHYIRILPGDKVTVELSPYDLSKGRITYRKK

Sequences:

>Translated_72_residues
MAKEEAITVDGTVLEPLPNAMFRVELENGHKVLAHISGKMRMHYIRILPGDKVTVELSPYDLSKGRITYRKK
>Mature_71_residues
AKEEAITVDGTVLEPLPNAMFRVELENGHKVLAHISGKMRMHYIRILPGDKVTVELSPYDLSKGRITYRKK

Specific function: No specific function has so far been attributed to this initiation factor; however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3

COG id: COG0361

COG function: function code J; Translation initiation factor 1 (IF-1)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1-like domain

Homologues:

Organism=Escherichia coli, GI1787110, Length=72, Percent_Identity=76.3888888888889, Blast_Score=115, Evalue=4e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IF1_LEPBJ (Q04PW0)

Other databases:

- EMBL:   CP000350
- RefSeq:   YP_801818.1
- ProteinModelPortal:   Q04PW0
- SMR:   Q04PW0
- STRING:   Q04PW0
- GeneID:   4411358
- GenomeReviews:   CP000350_GR
- KEGG:   lbj:LBJ_2637
- eggNOG:   COG0361
- HOGENOM:   HBG286099
- OMA:   KMRMHFI
- PhylomeDB:   Q04PW0
- ProtClustDB:   PRK00276
- BioCyc:   LBOR355277:LBJ_2637-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00075
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR022967
- InterPro:   IPR006196
- InterPro:   IPR004368
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00316
- TIGRFAMs:   TIGR00008

Pfam domain/function: PF01176 eIF-1a; SSF50249 Nucleic_acid_OB

EC number: NA

Molecular weight: Translated: 8194; Mature: 8063

Theoretical pI: Translated: 9.93; Mature: 9.93

Prosite motif: PS50832 S1_IF1_TYPE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKEEAITVDGTVLEPLPNAMFRVELENGHKVLAHISGKMRMHYIRILPGDKVTVELSPY
CCCCCEEEECCEEECCCCCEEEEEEECCCCEEEEEECCCEEEEEEEECCCCEEEEEECCC
DLSKGRITYRKK
CCCCCEEEEECC
>Mature Secondary Structure 
AKEEAITVDGTVLEPLPNAMFRVELENGHKVLAHISGKMRMHYIRILPGDKVTVELSPY
CCCCEEEECCEEECCCCCEEEEEEECCCCEEEEEECCCEEEEEEEECCCCEEEEEECCC
DLSKGRITYRKK
CCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA