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The map label for this gene is idnR [H]

Identifier: 116249283

GI number: 116249283

Start: 672287

End: 673261

Strand: Direct

Name: idnR [H]

Synonym: pRL120618

Alternate gene names: 116249283

Gene position: 672287-673261 (Clockwise)

Preceding gene: 116249271

Following gene: 116249284

Centisome position: 77.27

GC content: 64.1

Gene sequence:

>975_bases
GTGACGCTTGCCGAGGTCGCGGAAGCGGCCGGTGTCGGCGAGAGCACGGTGTCGCGCGTACTGCGCAACCACGGTTCGTT
TTCCGGCAAGACGCGGGAGCGGGTAATGGCCGCCGTCGAGCGGCTGGGATACGTGCCGAACCGGATCGCAGGAACGCTTG
CCTCTACCGGTTCGCGTCTTGTCGCCTTCGTCATTCCCTCTTTGTCCAACATCGTCTTTCCCGATGTGCTGCGCGGTGCC
AGTGCCGTTCTGGAGGAAAACCGGTATCAGGCGGTTTTCTCCGTGACCGACTATGATCCGGGCAAGGAGGAAGCGCTCGC
CGCCGCGATGCTTGCCTGGCGGCCGGCGGCGGTCATGCTGGCGGGATGCGAGCATACCGAGGGCACGGTGAAGATGCTGC
GCGCCAGCGGGTGTCGGATCGTCGAACTGCTCGATCTCGACGGCGATGCTCTCGACATCGCGGTCGGCTTCTCGAACCGC
GCGGCTGGACGGGAGAGCGCTGCCTTCCTGCTCAAACAGGGGTATCGCCGGATCGGCTATGTCGGTCACGACCTGAACCG
CGATACCCGTGCCGGCAAGCGTTTTTCCAGCTTTTGCGAAACGCTCGATGCGCATGACACCCAGCTCGTCGCCCGTGAAA
TTCTCGCCGGCGCTTCGTCCGTGGAAAATGGCAGGCTGGGGCTGGAGCGGCTGCTTGCCCGGACGGCCGATCTCGATGCG
GTTTATTTCTCCAACGACGACATGGCGCTGGGCGGCTATTTTCACTGTCTGGCCGAGGGGATAGCGATCCCCTCGAAGCT
CGCCATTTTCGGCTATAACGGCCTCGATATCGGCCGGGCAACACCGCAGCCATTGTCGACCATCCGAACGCCGCGCGTGG
CGACGGGGCAGATCGCCGCGCAGCTGATCGTCGCCAATGCACCGCCGCAGGCCGTCGATCTCGGCTTTGAACTGATCGAA
GGGGCAACCGCCTAA

Upstream 100 bases:

>100_bases
GAAAGATGGGGCAGAGCGGTGGTCATCGGGCGGGCAGGCCGGGCAACCACCTCAACAGTCGGGTTCAAACGTAACGATGG
AATTCAAACATCAACCGACG

Downstream 100 bases:

>100_bases
TATATTGGAGGAACTGTCATGTCCGACGCGCGCCTGCGTGAGGAAATCTGCCGATACGGCCGCTCGCTGTTCGAACGCGG
GCTGACGCCCGGTTCGTCGG

Product: LacI family transcriptional regulator

Products: NA

Alternate protein names: L-idonate regulatory protein [H]

Number of amino acids: Translated: 324; Mature: 323

Protein sequence:

>324_residues
MTLAEVAEAAGVGESTVSRVLRNHGSFSGKTRERVMAAVERLGYVPNRIAGTLASTGSRLVAFVIPSLSNIVFPDVLRGA
SAVLEENRYQAVFSVTDYDPGKEEALAAAMLAWRPAAVMLAGCEHTEGTVKMLRASGCRIVELLDLDGDALDIAVGFSNR
AAGRESAAFLLKQGYRRIGYVGHDLNRDTRAGKRFSSFCETLDAHDTQLVAREILAGASSVENGRLGLERLLARTADLDA
VYFSNDDMALGGYFHCLAEGIAIPSKLAIFGYNGLDIGRATPQPLSTIRTPRVATGQIAAQLIVANAPPQAVDLGFELIE
GATA

Sequences:

>Translated_324_residues
MTLAEVAEAAGVGESTVSRVLRNHGSFSGKTRERVMAAVERLGYVPNRIAGTLASTGSRLVAFVIPSLSNIVFPDVLRGA
SAVLEENRYQAVFSVTDYDPGKEEALAAAMLAWRPAAVMLAGCEHTEGTVKMLRASGCRIVELLDLDGDALDIAVGFSNR
AAGRESAAFLLKQGYRRIGYVGHDLNRDTRAGKRFSSFCETLDAHDTQLVAREILAGASSVENGRLGLERLLARTADLDA
VYFSNDDMALGGYFHCLAEGIAIPSKLAIFGYNGLDIGRATPQPLSTIRTPRVATGQIAAQLIVANAPPQAVDLGFELIE
GATA
>Mature_323_residues
TLAEVAEAAGVGESTVSRVLRNHGSFSGKTRERVMAAVERLGYVPNRIAGTLASTGSRLVAFVIPSLSNIVFPDVLRGAS
AVLEENRYQAVFSVTDYDPGKEEALAAAMLAWRPAAVMLAGCEHTEGTVKMLRASGCRIVELLDLDGDALDIAVGFSNRA
AGRESAAFLLKQGYRRIGYVGHDLNRDTRAGKRFSSFCETLDAHDTQLVAREILAGASSVENGRLGLERLLARTADLDAV
YFSNDDMALGGYFHCLAEGIAIPSKLAIFGYNGLDIGRATPQPLSTIRTPRVATGQIAAQLIVANAPPQAVDLGFELIEG
ATA

Specific function: Idn operon regulator. May repress gntKU and gntT genes when growing on L-idonate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790715, Length=329, Percent_Identity=32.8267477203647, Blast_Score=195, Evalue=3e-51,
Organism=Escherichia coli, GI48994940, Length=327, Percent_Identity=35.1681957186544, Blast_Score=191, Evalue=4e-50,
Organism=Escherichia coli, GI1788474, Length=304, Percent_Identity=27.9605263157895, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI1789068, Length=294, Percent_Identity=26.530612244898, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1790369, Length=327, Percent_Identity=23.8532110091743, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1787948, Length=326, Percent_Identity=22.3926380368098, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1790194, Length=306, Percent_Identity=22.5490196078431, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787580, Length=339, Percent_Identity=25.3687315634218, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1786540, Length=317, Percent_Identity=27.1293375394322, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787906, Length=270, Percent_Identity=28.8888888888889, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789202, Length=294, Percent_Identity=24.1496598639456, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790689, Length=255, Percent_Identity=27.0588235294118, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 34414; Mature: 34282

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLAEVAEAAGVGESTVSRVLRNHGSFSGKTRERVMAAVERLGYVPNRIAGTLASTGSRL
CCHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCE
VAFVIPSLSNIVFPDVLRGASAVLEENRYQAVFSVTDYDPGKEEALAAAMLAWRPAAVML
EHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHCCHHHEE
AGCEHTEGTVKMLRASGCRIVELLDLDGDALDIAVGFSNRAAGRESAAFLLKQGYRRIGY
ECCCCCCHHHHHHHHCCCEEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCC
VGHDLNRDTRAGKRFSSFCETLDAHDTQLVAREILAGASSVENGRLGLERLLARTADLDA
CCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCE
VYFSNDDMALGGYFHCLAEGIAIPSKLAIFGYNGLDIGRATPQPLSTIRTPRVATGQIAA
EEECCCCEEHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCHHHHCCCCCCHHHHHH
QLIVANAPPQAVDLGFELIEGATA
EEEEECCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TLAEVAEAAGVGESTVSRVLRNHGSFSGKTRERVMAAVERLGYVPNRIAGTLASTGSRL
CHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCE
VAFVIPSLSNIVFPDVLRGASAVLEENRYQAVFSVTDYDPGKEEALAAAMLAWRPAAVML
EHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHCCHHHEE
AGCEHTEGTVKMLRASGCRIVELLDLDGDALDIAVGFSNRAAGRESAAFLLKQGYRRIGY
ECCCCCCHHHHHHHHCCCEEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCC
VGHDLNRDTRAGKRFSSFCETLDAHDTQLVAREILAGASSVENGRLGLERLLARTADLDA
CCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCE
VYFSNDDMALGGYFHCLAEGIAIPSKLAIFGYNGLDIGRATPQPLSTIRTPRVATGQIAA
EEECCCCEEHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCHHHHCCCCCCHHHHHH
QLIVANAPPQAVDLGFELIEGATA
EEEEECCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 9658018 [H]