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The map label for this gene is eryB [H]

Identifier: 116248875

GI number: 116248875

Start: 214879

End: 216390

Strand: Direct

Name: eryB [H]

Synonym: pRL120205

Alternate gene names: 116248875

Gene position: 214879-216390 (Clockwise)

Preceding gene: 116248874

Following gene: 116248876

Centisome position: 24.7

GC content: 62.7

Gene sequence:

>1512_bases
ATGACCGAACCCGAACTCCTGGATCTCTTCGTCATCGGCGGAGGCATCAACGGCGCGGGGATAGCACGCGATGCTGCCGG
CCGCGGCCTGAAGGTCGTGCTGTGCGAAAAGGACGATCTGGCACAGGGAACCTCGTCGCGTTCGGGCAAGCTGGTGCATG
GCGGTCTGCGTTACCTCGAATATTACGAATTCCGCCTGGTGCGTGAGGCGCTGATCGAGCGTGAAGTGCTGCTCAATGCC
GCGCCGCATATCATCTGGCCGATGCGCTTCGTCCTGCCGCACAGCCCTGAGGATCGCCCCGCATGGCTCGTGCGTCTCGG
CCTCTTCCTCTACGATCACCTCGGCGGTCGCAAGAAGCTCCCCGGGACACGAACGCTCAATCTGCTCCGCGACCCGGAAG
GCACGCCGATCCTCGATCAATACACACGCGGCTTTGAATATTCCGATTGCTGGGTCGACGACGCCCGCCTCGTGACCTTG
AATGCGGTGAGCGCAGCGGAAAACGGCGCTCTGGTGCTGACCCGCTCGCCGGCCGTGTCGGCCCGTCGCGAGAATGGCGG
TTGGACCGTGGTCACCAAAAGCAACGCCACGGGGGAGACGCGAACTTTCCGTGCCAAATGTCTGGTGAACTGCGCCGGCC
CCTGGGTGATGGACATCATCAATCGCGTCGCCGGTTCGAACTCCGGCCGCAACGTCCGCCTCGTCAAGGGCAGCCACATC
ATCGTGCCGAAGTTCTGGGCGGGCGCCAATGCCTATCTGGTGCAGAACCACGACAAGCGCGTCATTTTCATCAATCCCTA
TGAGGGCGACAAGGCGTTGATCGGGACGACCGATATCGCTTACGAAGGCCGGGCCGAGGATGTTGCCGCCGACGAGACGG
AAATCGAGTATCTGCTGAAGGCGGTCAATCGCTACTTCAAGGAAAAGCTGCGTCGCCACGACGTACTGCACAGCTTCTCC
GGCGTGCGCCCGCTGTTTGACGACGGCAAGGGCAACCCGTCCGCCGTTACCCGCGACTATGTCTTCGATCTCGACGAGAC
AGGCGGCGCTCCGCTGCTCAACGTCTTCGGCGGCAAGATCACCACATTCCGCGAGCTCGCTGAACGCGGCATGCAGCGCC
TGAAGCACATCTTCCCGAACATGGGAGGCGACTGGACGGAGAAGGCGCCGCTGCCCGGCGGCGAAATTCCGAATGCCGAT
TACGAGAGCTTTGCCAACAGCCTGCGCGATATCTATCCCTGGATGCCGCGCAAGCTCGTGCATCACTACGGCCGTCTCTA
TGGCGCCCGCGCCAGGAATGTGGTTGCCGGTGCGACTGGCATAGAAGGGCTTGGGCGGCATTTCGGCGGACAGCTCTACG
AAGCTGAGGCCCGCTATCTCGTCGCCACGGAATGGGCCGAAACGGCCGACGACATCCTCTATCGCCGCACCAAGCACTAC
CTCCATCTGAACGAAGCGGAGCGCGCGGCCTTTGGCGAGTGGTTTGCTTCAACCCGCCTTGCCGCCGCCTGA

Upstream 100 bases:

>100_bases
GCCAGGCAATGACGCCCGCCTGGGACAAGCTTGCCGTAGCCGCAACGACGTCGCCGCTGGGCGCGTAATTCTGATGCAGC
AGGCATCGAAGGAGCATGAC

Downstream 100 bases:

>100_bases
AGGATGCCGCCATGCCGCTGACCCTTTCGCTCAATACCAATCCGCTGGTGAACCGCTTCGCCGACCCAGACGATCTGATC
GATACGGTTGCGCGCGACCT

Product: glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 503; Mature: 502

Protein sequence:

>503_residues
MTEPELLDLFVIGGGINGAGIARDAAGRGLKVVLCEKDDLAQGTSSRSGKLVHGGLRYLEYYEFRLVREALIEREVLLNA
APHIIWPMRFVLPHSPEDRPAWLVRLGLFLYDHLGGRKKLPGTRTLNLLRDPEGTPILDQYTRGFEYSDCWVDDARLVTL
NAVSAAENGALVLTRSPAVSARRENGGWTVVTKSNATGETRTFRAKCLVNCAGPWVMDIINRVAGSNSGRNVRLVKGSHI
IVPKFWAGANAYLVQNHDKRVIFINPYEGDKALIGTTDIAYEGRAEDVAADETEIEYLLKAVNRYFKEKLRRHDVLHSFS
GVRPLFDDGKGNPSAVTRDYVFDLDETGGAPLLNVFGGKITTFRELAERGMQRLKHIFPNMGGDWTEKAPLPGGEIPNAD
YESFANSLRDIYPWMPRKLVHHYGRLYGARARNVVAGATGIEGLGRHFGGQLYEAEARYLVATEWAETADDILYRRTKHY
LHLNEAERAAFGEWFASTRLAAA

Sequences:

>Translated_503_residues
MTEPELLDLFVIGGGINGAGIARDAAGRGLKVVLCEKDDLAQGTSSRSGKLVHGGLRYLEYYEFRLVREALIEREVLLNA
APHIIWPMRFVLPHSPEDRPAWLVRLGLFLYDHLGGRKKLPGTRTLNLLRDPEGTPILDQYTRGFEYSDCWVDDARLVTL
NAVSAAENGALVLTRSPAVSARRENGGWTVVTKSNATGETRTFRAKCLVNCAGPWVMDIINRVAGSNSGRNVRLVKGSHI
IVPKFWAGANAYLVQNHDKRVIFINPYEGDKALIGTTDIAYEGRAEDVAADETEIEYLLKAVNRYFKEKLRRHDVLHSFS
GVRPLFDDGKGNPSAVTRDYVFDLDETGGAPLLNVFGGKITTFRELAERGMQRLKHIFPNMGGDWTEKAPLPGGEIPNAD
YESFANSLRDIYPWMPRKLVHHYGRLYGARARNVVAGATGIEGLGRHFGGQLYEAEARYLVATEWAETADDILYRRTKHY
LHLNEAERAAFGEWFASTRLAAA
>Mature_502_residues
TEPELLDLFVIGGGINGAGIARDAAGRGLKVVLCEKDDLAQGTSSRSGKLVHGGLRYLEYYEFRLVREALIEREVLLNAA
PHIIWPMRFVLPHSPEDRPAWLVRLGLFLYDHLGGRKKLPGTRTLNLLRDPEGTPILDQYTRGFEYSDCWVDDARLVTLN
AVSAAENGALVLTRSPAVSARRENGGWTVVTKSNATGETRTFRAKCLVNCAGPWVMDIINRVAGSNSGRNVRLVKGSHII
VPKFWAGANAYLVQNHDKRVIFINPYEGDKALIGTTDIAYEGRAEDVAADETEIEYLLKAVNRYFKEKLRRHDVLHSFSG
VRPLFDDGKGNPSAVTRDYVFDLDETGGAPLLNVFGGKITTFRELAERGMQRLKHIFPNMGGDWTEKAPLPGGEIPNADY
ESFANSLRDIYPWMPRKLVHHYGRLYGARARNVVAGATGIEGLGRHFGGQLYEAEARYLVATEWAETADDILYRRTKHYL
HLNEAERAAFGEWFASTRLAAA

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=525, Percent_Identity=31.4285714285714, Blast_Score=197, Evalue=1e-50,
Organism=Homo sapiens, GI285002231, Length=525, Percent_Identity=31.4285714285714, Blast_Score=197, Evalue=1e-50,
Organism=Escherichia coli, GI2367226, Length=478, Percent_Identity=48.1171548117155, Blast_Score=455, Evalue=1e-129,
Organism=Escherichia coli, GI1788574, Length=387, Percent_Identity=27.6485788113695, Blast_Score=91, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI115534726, Length=501, Percent_Identity=30.7385229540918, Blast_Score=167, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI17509253, Length=508, Percent_Identity=31.1023622047244, Blast_Score=161, Evalue=7e-40,
Organism=Saccharomyces cerevisiae, GI6322036, Length=546, Percent_Identity=28.5714285714286, Blast_Score=176, Evalue=9e-45,
Organism=Drosophila melanogaster, GI161077125, Length=518, Percent_Identity=31.0810810810811, Blast_Score=176, Evalue=3e-44,
Organism=Drosophila melanogaster, GI24653942, Length=518, Percent_Identity=31.0810810810811, Blast_Score=176, Evalue=3e-44,
Organism=Drosophila melanogaster, GI24653944, Length=518, Percent_Identity=31.0810810810811, Blast_Score=176, Evalue=3e-44,
Organism=Drosophila melanogaster, GI20130025, Length=518, Percent_Identity=31.0810810810811, Blast_Score=176, Evalue=3e-44,
Organism=Drosophila melanogaster, GI24586295, Length=510, Percent_Identity=28.4313725490196, Blast_Score=125, Evalue=5e-29,
Organism=Drosophila melanogaster, GI19921278, Length=492, Percent_Identity=22.5609756097561, Blast_Score=97, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 56056; Mature: 55925

Theoretical pI: Translated: 8.02; Mature: 8.02

Prosite motif: PS00977 FAD_G3PDH_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEPELLDLFVIGGGINGAGIARDAAGRGLKVVLCEKDDLAQGTSSRSGKLVHGGLRYLE
CCCCCEEEEEEEECCCCCCCCCHHCCCCCEEEEEECCCCCCCCCCCCCCCEEEHHHHHHH
YYEFRLVREALIEREVLLNAAPHIIWPMRFVLPHSPEDRPAWLVRLGLFLYDHLGGRKKL
HHHHHHHHHHHHHHHHHHHCCCCCEECHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCC
PGTRTLNLLRDPEGTPILDQYTRGFEYSDCWVDDARLVTLNAVSAAENGALVLTRSPAVS
CCCCEEHEEECCCCCCCHHHHHCCCCCCCCEECCCEEEEEEEEECCCCCEEEEEECCCCC
ARRENGGWTVVTKSNATGETRTFRAKCLVNCAGPWVMDIINRVAGSNSGRNVRLVKGSHI
CEECCCCEEEEECCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHCCCCCCEEEEEECCEE
IVPKFWAGANAYLVQNHDKRVIFINPYEGDKALIGTTDIAYEGRAEDVAADETEIEYLLK
EEEECCCCCCEEEEECCCCEEEEEECCCCCEEEEECCCEEECCCCCCCCCCHHHHHHHHH
AVNRYFKEKLRRHDVLHSFSGVRPLFDDGKGNPSAVTRDYVFDLDETGGAPLLNVFGGKI
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEHEEEEECCCCCCCCCHHHCCCCH
TTFRELAERGMQRLKHIFPNMGGDWTEKAPLPGGEIPNADYESFANSLRDIYPWMPRKLV
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHH
HHYGRLYGARARNVVAGATGIEGLGRHFGGQLYEAEARYLVATEWAETADDILYRRTKHY
HHHHHHHCCCCCCEEECCCCHHHHHHHHCCCEEECCCCEEEEECHHHHHHHHHHHHHHHE
LHLNEAERAAFGEWFASTRLAAA
EEECHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TEPELLDLFVIGGGINGAGIARDAAGRGLKVVLCEKDDLAQGTSSRSGKLVHGGLRYLE
CCCCEEEEEEEECCCCCCCCCHHCCCCCEEEEEECCCCCCCCCCCCCCCEEEHHHHHHH
YYEFRLVREALIEREVLLNAAPHIIWPMRFVLPHSPEDRPAWLVRLGLFLYDHLGGRKKL
HHHHHHHHHHHHHHHHHHHCCCCCEECHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCC
PGTRTLNLLRDPEGTPILDQYTRGFEYSDCWVDDARLVTLNAVSAAENGALVLTRSPAVS
CCCCEEHEEECCCCCCCHHHHHCCCCCCCCEECCCEEEEEEEEECCCCCEEEEEECCCCC
ARRENGGWTVVTKSNATGETRTFRAKCLVNCAGPWVMDIINRVAGSNSGRNVRLVKGSHI
CEECCCCEEEEECCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHCCCCCCEEEEEECCEE
IVPKFWAGANAYLVQNHDKRVIFINPYEGDKALIGTTDIAYEGRAEDVAADETEIEYLLK
EEEECCCCCCEEEEECCCCEEEEEECCCCCEEEEECCCEEECCCCCCCCCCHHHHHHHHH
AVNRYFKEKLRRHDVLHSFSGVRPLFDDGKGNPSAVTRDYVFDLDETGGAPLLNVFGGKI
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEHEEEEECCCCCCCCCHHHCCCCH
TTFRELAERGMQRLKHIFPNMGGDWTEKAPLPGGEIPNADYESFANSLRDIYPWMPRKLV
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHH
HHYGRLYGARARNVVAGATGIEGLGRHFGGQLYEAEARYLVATEWAETADDILYRRTKHY
HHHHHHHCCCCCCEEECCCCHHHHHHHHCCCEEECCCCEEEEECHHHHHHHHHHHHHHHE
LHLNEAERAAFGEWFASTRLAAA
EEECHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8157588; 10984043 [H]