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The map label for this gene is eryA [H]

Identifier: 116248874

GI number: 116248874

Start: 213245

End: 214846

Strand: Direct

Name: eryA [H]

Synonym: pRL120204

Alternate gene names: 116248874

Gene position: 213245-214846 (Clockwise)

Preceding gene: 116248866

Following gene: 116248875

Centisome position: 24.51

GC content: 64.67

Gene sequence:

>1602_bases
TTGCTAGGATGGCGAGATAGGCCTGCAATGACATCGACCCAGAAGATCATCATTGGCATAGATGCCGGCACCTCGGTCAT
CAAGGCTGTCGCCTTCGATCTGTCCGGGCGCCAGATTGCTACGGCCTCCGTTCGAAACCGATATGCCACAGGAGACGATG
GTTCGGCAACGCAGTCGCTGGATCAGACCTGGCTCGATTGCGCCAGCGCGTTGCGTGGTCTCGGCGAAAAAGTCCCTGAT
CTTGCGTCACGCACCGCAGCCATCGCCGTCACCGGACAGGGCGACGGCACCTGGCTCGTCGGCCGAGCCAATAGGCCGGT
TGCCGATGCCTGGCTGTGGCTCGACGCGCGCGCCGCGCCGACGGTGACGTCGCTCGCGGGCGGAACGCAGAATCGTGCCC
GCTTCGAGACGACGGGCACCGGCCTCAACACTTGCCAGCAGGGTGCGCAACTCGCCCATATGGACCGCTTCACGCCGGAC
CTTCTCGATCGGGCGGAGACGGCGCTGCACTGCAAGGACTGGCTCTATCTCAACCTCACAGGCGTGCGGGCAACCGATCC
ATCGGAGGCGAGTTTCACCTTTGGCAATTTCAGAACACGCCAGTATGATGCCGTGGTGATCGACGCGCTCGGCCTTGAGC
ACAGACGCGGGCTCCTGCCCGAAATCATCGACGGCAGCGAGATCAGCCACCCGCTGACATCGGAGGCGGCTAAGGCCTGC
GGTCTTCTTGCCGGAACGCCGGTCTGCCTCGGCTATGTCGACATGGTGATGACGGCGCTTGGTGCAGGCGTGCGCAGCGG
CGCTCGCAACGCCGCCTGCTCGACGATCGGCTCGACCGGGGTGCACTTGCGCGCCAAGGCCGTTGCCGACGTTCAGCTCA
ATCGCGAGGGCACCGGCTATGTGATCGCCCTGCCCATTCCCGGCATCGTCACCCAGGTCCAGACCAATATGGGCGCCACG
ATCAACATCGACTGGATCCTTAATGTCGCCGCCTATCTGATGGCCGAGGCAGGCAAGCCTGCTTCGCACGCAGACCTCAT
TGCACGCATCGACGGCTGGTTTGCAGAAAGCCGACCGGGGTCGGTGCTTTACCATCCCTACATTTCCGAAGCGGGCGAAC
GTGGGCCTTTCGTCAACGCCAATGCGCGCGCGGGCTTCACCGGGCTTTCGATGCGTCACGGTTTCCCCGACCTGCTGCGC
AGCGTGATCGAAGGGTTGGGGCTTGCGACCCGCGACTGCTACGCGGCGATGGGCGCGATGCCAGAGGAGCTGCGGGTCAC
CGGCGGCGCAACACGCTCCGTCGCCCTTCGCCGTTCACTTTCGGCCGCCGTCAACGCACCGATCCGCCAGTCGCGCCGCG
AGGAGACGGGGGCGGCCGGCGTGGCGATGATGGCTGCGGTGGCTGTCGGCATCTATTCGAGCATGGACGATTGCATTGCC
GACTGGGTGACGCCGCTGCTCGGAGATCCGGAAACACCGGATGCCAGCGAGGCCCACCGGTTCGACCGGCTTTTTTCTGC
TTATACCGATGTACGCCAGGCAATGACGCCCGCCTGGGACAAGCTTGCCGTAGCCGCAACGACGTCGCCGCTGGGCGCGT
AA

Upstream 100 bases:

>100_bases
ATTAAAAACCGAAGTTGGCAGCCGGATGCATCATCCCAGAGAGTTTAGGGATCGGGAGGACTTCAGATGGATTTGATGCG
CGTATTGCCCGCCGCGACGC

Downstream 100 bases:

>100_bases
TTCTGATGCAGCAGGCATCGAAGGAGCATGACATGACCGAACCCGAACTCCTGGATCTCTTCGTCATCGGCGGAGGCATC
AACGGCGCGGGGATAGCACG

Product: putative eryithritol kinase

Products: NA

Alternate protein names: Xylulokinase [H]

Number of amino acids: Translated: 533; Mature: 533

Protein sequence:

>533_residues
MLGWRDRPAMTSTQKIIIGIDAGTSVIKAVAFDLSGRQIATASVRNRYATGDDGSATQSLDQTWLDCASALRGLGEKVPD
LASRTAAIAVTGQGDGTWLVGRANRPVADAWLWLDARAAPTVTSLAGGTQNRARFETTGTGLNTCQQGAQLAHMDRFTPD
LLDRAETALHCKDWLYLNLTGVRATDPSEASFTFGNFRTRQYDAVVIDALGLEHRRGLLPEIIDGSEISHPLTSEAAKAC
GLLAGTPVCLGYVDMVMTALGAGVRSGARNAACSTIGSTGVHLRAKAVADVQLNREGTGYVIALPIPGIVTQVQTNMGAT
INIDWILNVAAYLMAEAGKPASHADLIARIDGWFAESRPGSVLYHPYISEAGERGPFVNANARAGFTGLSMRHGFPDLLR
SVIEGLGLATRDCYAAMGAMPEELRVTGGATRSVALRRSLSAAVNAPIRQSRREETGAAGVAMMAAVAVGIYSSMDDCIA
DWVTPLLGDPETPDASEAHRFDRLFSAYTDVRQAMTPAWDKLAVAATTSPLGA

Sequences:

>Translated_533_residues
MLGWRDRPAMTSTQKIIIGIDAGTSVIKAVAFDLSGRQIATASVRNRYATGDDGSATQSLDQTWLDCASALRGLGEKVPD
LASRTAAIAVTGQGDGTWLVGRANRPVADAWLWLDARAAPTVTSLAGGTQNRARFETTGTGLNTCQQGAQLAHMDRFTPD
LLDRAETALHCKDWLYLNLTGVRATDPSEASFTFGNFRTRQYDAVVIDALGLEHRRGLLPEIIDGSEISHPLTSEAAKAC
GLLAGTPVCLGYVDMVMTALGAGVRSGARNAACSTIGSTGVHLRAKAVADVQLNREGTGYVIALPIPGIVTQVQTNMGAT
INIDWILNVAAYLMAEAGKPASHADLIARIDGWFAESRPGSVLYHPYISEAGERGPFVNANARAGFTGLSMRHGFPDLLR
SVIEGLGLATRDCYAAMGAMPEELRVTGGATRSVALRRSLSAAVNAPIRQSRREETGAAGVAMMAAVAVGIYSSMDDCIA
DWVTPLLGDPETPDASEAHRFDRLFSAYTDVRQAMTPAWDKLAVAATTSPLGA
>Mature_533_residues
MLGWRDRPAMTSTQKIIIGIDAGTSVIKAVAFDLSGRQIATASVRNRYATGDDGSATQSLDQTWLDCASALRGLGEKVPD
LASRTAAIAVTGQGDGTWLVGRANRPVADAWLWLDARAAPTVTSLAGGTQNRARFETTGTGLNTCQQGAQLAHMDRFTPD
LLDRAETALHCKDWLYLNLTGVRATDPSEASFTFGNFRTRQYDAVVIDALGLEHRRGLLPEIIDGSEISHPLTSEAAKAC
GLLAGTPVCLGYVDMVMTALGAGVRSGARNAACSTIGSTGVHLRAKAVADVQLNREGTGYVIALPIPGIVTQVQTNMGAT
INIDWILNVAAYLMAEAGKPASHADLIARIDGWFAESRPGSVLYHPYISEAGERGPFVNANARAGFTGLSMRHGFPDLLR
SVIEGLGLATRDCYAAMGAMPEELRVTGGATRSVALRRSLSAAVNAPIRQSRREETGAAGVAMMAAVAVGIYSSMDDCIA
DWVTPLLGDPETPDASEAHRFDRLFSAYTDVRQAMTPAWDKLAVAATTSPLGA

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Escherichia coli, GI1789987, Length=509, Percent_Identity=27.8978388998035, Blast_Score=118, Evalue=8e-28,
Organism=Escherichia coli, GI1790005, Length=513, Percent_Identity=23.1968810916179, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1787789, Length=529, Percent_Identity=25.8979206049149, Blast_Score=103, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006000 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.17 [H]

Molecular weight: Translated: 56348; Mature: 56348

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGWRDRPAMTSTQKIIIGIDAGTSVIKAVAFDLSGRQIATASVRNRYATGDDGSATQSL
CCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHCCCCCEEEEHHHHCCCCCCCCCCHHHHH
DQTWLDCASALRGLGEKVPDLASRTAAIAVTGQGDGTWLVGRANRPVADAWLWLDARAAP
HHHHHHHHHHHHHHHHHCHHHHCCCEEEEEEECCCCEEEEECCCCCHHHEEEEEECCCCC
TVTSLAGGTQNRARFETTGTGLNTCQQGAQLAHMDRFTPDLLDRAETALHCKDWLYLNLT
CHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHEECCEEEEEEE
GVRATDPSEASFTFGNFRTRQYDAVVIDALGLEHRRGLLPEIIDGSEISHPLTSEAAKAC
ECCCCCCCCCCEEECCCCCCEECEEEEEHHCCHHHCCCCCHHCCCCCCCCCHHHHHHHHH
GLLAGTPVCLGYVDMVMTALGAGVRSGARNAACSTIGSTGVHLRAKAVADVQLNREGTGY
HHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCEEEEEEEEEEEECCCCCCE
VIALPIPGIVTQVQTNMGATINIDWILNVAAYLMAEAGKPASHADLIARIDGWFAESRPG
EEEECCCCHHHHHHHCCCCEEEEHHHHHHHHHHHHHCCCCCHHHHHHHHHHCHHCCCCCC
SVLYHPYISEAGERGPFVNANARAGFTGLSMRHGFPDLLRSVIEGLGLATRDCYAAMGAM
CEEECCHHHCCCCCCCEECCCCCCCCCCCHHHCCCHHHHHHHHHHCCCCHHHHHHHHCCC
PEELRVTGGATRSVALRRSLSAAVNAPIRQSRREETGAAGVAMMAAVAVGIYSSMDDCIA
CHHHEECCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
DWVTPLLGDPETPDASEAHRFDRLFSAYTDVRQAMTPAWDKLAVAATTSPLGA
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEECCCCCCC
>Mature Secondary Structure
MLGWRDRPAMTSTQKIIIGIDAGTSVIKAVAFDLSGRQIATASVRNRYATGDDGSATQSL
CCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHCCCCCEEEEHHHHCCCCCCCCCCHHHHH
DQTWLDCASALRGLGEKVPDLASRTAAIAVTGQGDGTWLVGRANRPVADAWLWLDARAAP
HHHHHHHHHHHHHHHHHCHHHHCCCEEEEEEECCCCEEEEECCCCCHHHEEEEEECCCCC
TVTSLAGGTQNRARFETTGTGLNTCQQGAQLAHMDRFTPDLLDRAETALHCKDWLYLNLT
CHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHEECCEEEEEEE
GVRATDPSEASFTFGNFRTRQYDAVVIDALGLEHRRGLLPEIIDGSEISHPLTSEAAKAC
ECCCCCCCCCCEEECCCCCCEECEEEEEHHCCHHHCCCCCHHCCCCCCCCCHHHHHHHHH
GLLAGTPVCLGYVDMVMTALGAGVRSGARNAACSTIGSTGVHLRAKAVADVQLNREGTGY
HHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCEEEEEEEEEEEECCCCCCE
VIALPIPGIVTQVQTNMGATINIDWILNVAAYLMAEAGKPASHADLIARIDGWFAESRPG
EEEECCCCHHHHHHHCCCCEEEEHHHHHHHHHHHHHCCCCCHHHHHHHHHHCHHCCCCCC
SVLYHPYISEAGERGPFVNANARAGFTGLSMRHGFPDLLRSVIEGLGLATRDCYAAMGAM
CEEECCHHHCCCCCCCEECCCCCCCCCCCHHHCCCHHHHHHHHHHCCCCHHHHHHHHCCC
PEELRVTGGATRSVALRRSLSAAVNAPIRQSRREETGAAGVAMMAAVAVGIYSSMDDCIA
CHHHEECCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
DWVTPLLGDPETPDASEAHRFDRLFSAYTDVRQAMTPAWDKLAVAATTSPLGA
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6320721; 8041620; 9278503 [H]