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The map label for this gene is moaE1 [H]

Identifier: 114800184

GI number: 114800184

Start: 1074111

End: 1074572

Strand: Reverse

Name: moaE1 [H]

Synonym: HNE_1067

Alternate gene names: 114800184

Gene position: 1074572-1074111 (Counterclockwise)

Preceding gene: 114799467

Following gene: 114799410

Centisome position: 29.0

GC content: 65.58

Gene sequence:

>462_bases
TTGATACGCCTGACAGACACCCCCTTCGATCCCGGAGACGAACTCACCCGTTTTACCGCCACCGCCGCCGGCAGCGGCGC
CATCGTCAGCTTCACCGGCCTGGTGCGCGGCCAGTCCAAAGGCGGCGCCGTCCAGTCCCTGTTCCTGCAAGCCTATTCCC
CCCTCACCGAGCGCGGCATCGCGCAGGCCGCAGAGGAAGCCCGCACGCGCTGGGCGCTCACAGGTCTCTCCATACTCCAT
CGAACCGGAAAAATGGCACCGGAAGACGCCATCGTCTTCGTCGCCACCGCCGCCCCCCACCGGCGCAGCGCCTTCGAGGC
CGCCGACTTCCTGATGGACTATCTGAAGACGCAGGCGGTATTCTGGAAAAAAGAAGTGACCGAGGCGGGCGACCAATGGA
TCGAACCGCGCCCCGAAGATTACACCGACGCTGCCCGCTGGGCAGGTCCGCAGGAGAGTTGA

Upstream 100 bases:

>100_bases
GTCCGCATCGCCATCAACAGCGAGATTGTGGTTGATCCCGCCCCGATCACCAACGCCGACGAGATCGCCTTCATGCCGCC
TGTCGGAGGGGGATGATCCC

Downstream 100 bases:

>100_bases
ACACGCATGCACGGCATCAATGAAAGCCTTCCCTTCAAGCCGGTCCGGATCTCCATCCTGATCGTCAGCGATACGCGCAC
GGAAGAAACCGACACCTCCG

Product: molybdopterin converting factor subunit 2

Products: NA

Alternate protein names: MPT synthase subunit 2; Molybdenum cofactor biosynthesis protein E; Molybdopterin-converting factor large subunit; Molybdopterin-converting factor subunit 2 [H]

Number of amino acids: Translated: 153; Mature: 153

Protein sequence:

>153_residues
MIRLTDTPFDPGDELTRFTATAAGSGAIVSFTGLVRGQSKGGAVQSLFLQAYSPLTERGIAQAAEEARTRWALTGLSILH
RTGKMAPEDAIVFVATAAPHRRSAFEAADFLMDYLKTQAVFWKKEVTEAGDQWIEPRPEDYTDAARWAGPQES

Sequences:

>Translated_153_residues
MIRLTDTPFDPGDELTRFTATAAGSGAIVSFTGLVRGQSKGGAVQSLFLQAYSPLTERGIAQAAEEARTRWALTGLSILH
RTGKMAPEDAIVFVATAAPHRRSAFEAADFLMDYLKTQAVFWKKEVTEAGDQWIEPRPEDYTDAARWAGPQES
>Mature_153_residues
MIRLTDTPFDPGDELTRFTATAAGSGAIVSFTGLVRGQSKGGAVQSLFLQAYSPLTERGIAQAAEEARTRWALTGLSILH
RTGKMAPEDAIVFVATAAPHRRSAFEAADFLMDYLKTQAVFWKKEVTEAGDQWIEPRPEDYTDAARWAGPQES

Specific function: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by moaD [H]

COG id: COG0314

COG function: function code H; Molybdopterin converting factor, large subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaE family [H]

Homologues:

Organism=Homo sapiens, GI4758732, Length=121, Percent_Identity=29.7520661157025, Blast_Score=79, Evalue=2e-15,
Organism=Escherichia coli, GI1787003, Length=140, Percent_Identity=46.4285714285714, Blast_Score=134, Evalue=3e-33,
Organism=Drosophila melanogaster, GI21356259, Length=139, Percent_Identity=30.2158273381295, Blast_Score=73, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003448 [H]

Pfam domain/function: PF02391 MoaE [H]

EC number: NA

Molecular weight: Translated: 16707; Mature: 16707

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRLTDTPFDPGDELTRFTATAAGSGAIVSFTGLVRGQSKGGAVQSLFLQAYSPLTERGI
CEECCCCCCCCCHHHHHHHHHCCCCCCEEEEEHHHCCCCCCCHHHHHHHHHHCCHHHHHH
AQAAEEARTRWALTGLSILHRTGKMAPEDAIVFVATAAPHRRSAFEAADFLMDYLKTQAV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHH
FWKKEVTEAGDQWIEPRPEDYTDAARWAGPQES
HHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCC
>Mature Secondary Structure
MIRLTDTPFDPGDELTRFTATAAGSGAIVSFTGLVRGQSKGGAVQSLFLQAYSPLTERGI
CEECCCCCCCCCHHHHHHHHHCCCCCCEEEEEHHHCCCCCCCHHHHHHHHHHCCHHHHHH
AQAAEEARTRWALTGLSILHRTGKMAPEDAIVFVATAAPHRRSAFEAADFLMDYLKTQAV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHH
FWKKEVTEAGDQWIEPRPEDYTDAARWAGPQES
HHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11259647 [H]