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The map label for this gene is grxC [H]

Identifier: 114800009

GI number: 114800009

Start: 3346034

End: 3346294

Strand: Reverse

Name: grxC [H]

Synonym: HNE_3169

Alternate gene names: 114800009

Gene position: 3346294-3346034 (Counterclockwise)

Preceding gene: 114797458

Following gene: 114798809

Centisome position: 90.32

GC content: 59.0

Gene sequence:

>261_bases
ATGGCGAAGGTTACGATTTATACCCGCGCATTCTGCCCTTACTGCACCCGCGCTTTGCAGGTGCTCAAGGACAAGGGTGT
CGAGCTCAATGAGATTGATGCAGGTATGGACCCCGCGCTGCGCGAAGAGATGGTCCAGCGCTCCAATGGTGGGCGTACAT
TCCCGCAGATATTCGTGGGGGAGACCCACATTGGCGGCTGTGACGACATGCTCGCGCTTGACCGTTCCGGCAAGCTCGAC
CCGATGCTTGCCAGCGTCTGA

Upstream 100 bases:

>100_bases
GCGTTGTCCGCGCCACGGATGTCACCATATAACGGTTTGGTGACGGGCTCAGGTCAGACTTGTCCTGAAATGTCCCGCTT
TGACGAAAGGATTTCGCCCC

Downstream 100 bases:

>100_bases
GGAGGCGCCCGCGTGATCCTTTACGCGCTTATCTGTCAGGACTGCGACCATGCCTTTGAAGGCTGGTTCGCCAGTTCGGA
AGCCTTTGACCGCCTGGCGA

Product: glutaredoxin 3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 86; Mature: 85

Protein sequence:

>86_residues
MAKVTIYTRAFCPYCTRALQVLKDKGVELNEIDAGMDPALREEMVQRSNGGRTFPQIFVGETHIGGCDDMLALDRSGKLD
PMLASV

Sequences:

>Translated_86_residues
MAKVTIYTRAFCPYCTRALQVLKDKGVELNEIDAGMDPALREEMVQRSNGGRTFPQIFVGETHIGGCDDMLALDRSGKLD
PMLASV
>Mature_85_residues
AKVTIYTRAFCPYCTRALQVLKDKGVELNEIDAGMDPALREEMVQRSNGGRTFPQIFVGETHIGGCDDMLALDRSGKLDP
MLASV

Specific function: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins [H]

COG id: COG0695

COG function: function code O; Glutaredoxin and related proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutaredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790039, Length=83, Percent_Identity=54.2168674698795, Blast_Score=91, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011767
- InterPro:   IPR002109
- InterPro:   IPR014025
- InterPro:   IPR011900
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00462 Glutaredoxin [H]

EC number: NA

Molecular weight: Translated: 9464; Mature: 9333

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS00195 GLUTAREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
5.8 %Met     (Translated Protein)
9.3 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
8.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKVTIYTRAFCPYCTRALQVLKDKGVELNEIDAGMDPALREEMVQRSNGGRTFPQIFVG
CCEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEC
ETHIGGCDDMLALDRSGKLDPMLASV
CCCCCCCCCCEECCCCCCCCCCCCCC
>Mature Secondary Structure 
AKVTIYTRAFCPYCTRALQVLKDKGVELNEIDAGMDPALREEMVQRSNGGRTFPQIFVG
CEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEC
ETHIGGCDDMLALDRSGKLDPMLASV
CCCCCCCCCCEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]