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The map label for this gene is hcpE [H]

Identifier: 114799890

GI number: 114799890

Start: 935626

End: 936954

Strand: Reverse

Name: hcpE [H]

Synonym: HNE_0919

Alternate gene names: 114799890

Gene position: 936954-935626 (Counterclockwise)

Preceding gene: 114797378

Following gene: 114799502

Centisome position: 25.29

GC content: 63.05

Gene sequence:

>1329_bases
ATGCCCTTCCGCTTTCAACAAATTCGCCATTTGGCACTGGCAGGGGCCGGCCTGGCCATAGCCTTGCTTGCCCCCTTCCA
GTCTGCAGAGGCGCAAGGCGGTTTGCCGCCGGGCGCGGAAAACTGGCCGGCAGCGTGTGAGGCGGGCGACATTGACGCCT
GCATCAATCAGGGCATCCGCCTGCTGCAGGGCATCGAGACGCCGGTGGACCTTCCAGGCGCGGCGCGGTTTGCCTCGAAG
GCCTGCCAGCTTGGCTCGCCCGATGACTGCCAGATTGCCTGGGAACTCTATAGCGGCGCGCATCCTGATTATGCCGGCGA
TACCGCCCGGATGGTGACAGTCGGCGCGGTTGCCTGCGACCAGGGCCTGACGACGCCGTGCAGCGATGCCGCGCTGCGCC
TGTTCACCGGTGATGGCGTGCCCAAGAATGTGGAACTGGCCCTGCCGGTCTATGCCAAGGCCTGCGACCTGGAAGACGCG
CTGGCCTGCGCCACTCTGGCCACGGAATATCTGGATGGGGACCAGGGCACAGCGATCAATGCCGAGCAAGCGGTGATCTA
TGGCAAGAAAGGCTGCGCGCTGGGTCAGCCCGATTCCTGCCGCGTGGTGGAGGCAGCTTATATGCTGCCGGACTATACGA
CCTTCGAGCCCAAGGCGGGCCTGGAATATGCCCTCGCCAATTGCGCGGACGGTTCCAAGGAAAGCTGCGTCAATCTTGGG
ATCGTCTACACCCAGATCGAAGAATATGATCTGGCTGCAGAGAATTTCGACAAGGCCTGCACCATGGAATATCCGGAGGC
GTGCGAAAGCTCGAAAATCCTGAAACAATGGCGCACCGAGGTTGCCGAATACGAAGCCTACCTCGCCCGGCTGGCCGAGC
AGAAGGCCGCGATCAACGCGCTGATTGCCTCAAGCGGCCATGACGCGGCCCTGAGCGCAGCGCTGAATGATTATCGCTCT
GCGGAACTTGCCGAATTTGTGACCGGTCAGGCGGGCAGTCTTTCAGGCTTTTCCACCAACAATCTCTATGTCGTCTCCTA
CTGGTTCGCCGGGCAGGCCACCGGCGCGGCGGCCGATCGGGAACTGGCCTCACGCGGCACAGGCCTCGAAGGCACCTTCG
GCGAAGGTACGAACACACCAGGCACCGCAGCGGCGCGCTATCAGGCCGCCTATGGCTCCAGCCCACCGAGCTATACTTCG
GCTTCGCCGGCCTCATCGGCGCCGCCGATGAAAAGCGTGGCGGACATCAAGGCCGCAACACGCGACCGGTATCGCTGGGC
CCACTGCACCATGAGCGGCAGCAATACCAGCGCCAAGGTTTGCCAATAG

Upstream 100 bases:

>100_bases
TCTTCGGGGGCATTACGGACCCGCTTTCCTTGCCTAGGATCATCGATGCATCCGGCTTCGACCGGATTCCCGACATGGTT
CAGCAACAAGGAGGCCGCCG

Downstream 100 bases:

>100_bases
GCGGCGTGACAGGGGCCGGGGATCGGTTCAGGATAGTCGCCTGATCCGATCCCCAGGCCCTGACATGCATCCAGCCCCCC
GCTTCCGCGAGACGGATCTG

Product: beta-lactamase family protein

Products: NA

Alternate protein names: Cysteine-rich protein E [H]

Number of amino acids: Translated: 442; Mature: 441

Protein sequence:

>442_residues
MPFRFQQIRHLALAGAGLAIALLAPFQSAEAQGGLPPGAENWPAACEAGDIDACINQGIRLLQGIETPVDLPGAARFASK
ACQLGSPDDCQIAWELYSGAHPDYAGDTARMVTVGAVACDQGLTTPCSDAALRLFTGDGVPKNVELALPVYAKACDLEDA
LACATLATEYLDGDQGTAINAEQAVIYGKKGCALGQPDSCRVVEAAYMLPDYTTFEPKAGLEYALANCADGSKESCVNLG
IVYTQIEEYDLAAENFDKACTMEYPEACESSKILKQWRTEVAEYEAYLARLAEQKAAINALIASSGHDAALSAALNDYRS
AELAEFVTGQAGSLSGFSTNNLYVVSYWFAGQATGAAADRELASRGTGLEGTFGEGTNTPGTAAARYQAAYGSSPPSYTS
ASPASSAPPMKSVADIKAATRDRYRWAHCTMSGSNTSAKVCQ

Sequences:

>Translated_442_residues
MPFRFQQIRHLALAGAGLAIALLAPFQSAEAQGGLPPGAENWPAACEAGDIDACINQGIRLLQGIETPVDLPGAARFASK
ACQLGSPDDCQIAWELYSGAHPDYAGDTARMVTVGAVACDQGLTTPCSDAALRLFTGDGVPKNVELALPVYAKACDLEDA
LACATLATEYLDGDQGTAINAEQAVIYGKKGCALGQPDSCRVVEAAYMLPDYTTFEPKAGLEYALANCADGSKESCVNLG
IVYTQIEEYDLAAENFDKACTMEYPEACESSKILKQWRTEVAEYEAYLARLAEQKAAINALIASSGHDAALSAALNDYRS
AELAEFVTGQAGSLSGFSTNNLYVVSYWFAGQATGAAADRELASRGTGLEGTFGEGTNTPGTAAARYQAAYGSSPPSYTS
ASPASSAPPMKSVADIKAATRDRYRWAHCTMSGSNTSAKVCQ
>Mature_441_residues
PFRFQQIRHLALAGAGLAIALLAPFQSAEAQGGLPPGAENWPAACEAGDIDACINQGIRLLQGIETPVDLPGAARFASKA
CQLGSPDDCQIAWELYSGAHPDYAGDTARMVTVGAVACDQGLTTPCSDAALRLFTGDGVPKNVELALPVYAKACDLEDAL
ACATLATEYLDGDQGTAINAEQAVIYGKKGCALGQPDSCRVVEAAYMLPDYTTFEPKAGLEYALANCADGSKESCVNLGI
VYTQIEEYDLAAENFDKACTMEYPEACESSKILKQWRTEVAEYEAYLARLAEQKAAINALIASSGHDAALSAALNDYRSA
ELAEFVTGQAGSLSGFSTNNLYVVSYWFAGQATGAAADRELASRGTGLEGTFGEGTNTPGTAAARYQAAYGSSPPSYTSA
SPASSAPPMKSVADIKAATRDRYRWAHCTMSGSNTSAKVCQ

Specific function: May hydrolyze 6-aminopenicillinic acid and 7- aminocephalosporanic acid (ACA) derivatives [H]

COG id: COG0790

COG function: function code R; FOG: TPR repeat, SEL1 subfamily

Gene ontology:

Cell location: Secreted (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 8 TPR repeats [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006597
- InterPro:   IPR011990 [H]

Pfam domain/function: PF08238 Sel1 [H]

EC number: =3.5.2.6 [H]

Molecular weight: Translated: 46307; Mature: 46176

Theoretical pI: Translated: 4.29; Mature: 4.29

Prosite motif: PS50005 TPR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFRFQQIRHLALAGAGLAIALLAPFQSAEAQGGLPPGAENWPAACEAGDIDACINQGIR
CCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
LLQGIETPVDLPGAARFASKACQLGSPDDCQIAWELYSGAHPDYAGDTARMVTVGAVACD
HHHHCCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCEEEEEEEHHHHC
QGLTTPCSDAALRLFTGDGVPKNVELALPVYAKACDLEDALACATLATEYLDGDQGTAIN
CCCCCCCCCCEEEEEECCCCCCCEEEEEEHHHHHCCHHHHHHHHHHHHHHHCCCCCCEEC
AEQAVIYGKKGCALGQPDSCRVVEAAYMLPDYTTFEPKAGLEYALANCADGSKESCVNLG
CCCEEEECCCCCCCCCCCCCCEEEHHHHCCCCCCCCCCCCHHHHHHHCCCCCHHHHEEEE
IVYTQIEEYDLAAENFDKACTMEYPEACESSKILKQWRTEVAEYEAYLARLAEQKAAINA
EEEEEHHHHHCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIASSGHDAALSAALNDYRSAELAEFVTGQAGSLSGFSTNNLYVVSYWFAGQATGAAADR
HHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCCCCCHHHH
ELASRGTGLEGTFGEGTNTPGTAAARYQAAYGSSPPSYTSASPASSAPPMKSVADIKAAT
HHHHCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
RDRYRWAHCTMSGSNTSAKVCQ
HCCEEEEEEEECCCCCCCCCCC
>Mature Secondary Structure 
PFRFQQIRHLALAGAGLAIALLAPFQSAEAQGGLPPGAENWPAACEAGDIDACINQGIR
CCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
LLQGIETPVDLPGAARFASKACQLGSPDDCQIAWELYSGAHPDYAGDTARMVTVGAVACD
HHHHCCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCEEEEEEEHHHHC
QGLTTPCSDAALRLFTGDGVPKNVELALPVYAKACDLEDALACATLATEYLDGDQGTAIN
CCCCCCCCCCEEEEEECCCCCCCEEEEEEHHHHHCCHHHHHHHHHHHHHHHCCCCCCEEC
AEQAVIYGKKGCALGQPDSCRVVEAAYMLPDYTTFEPKAGLEYALANCADGSKESCVNLG
CCCEEEECCCCCCCCCCCCCCEEEHHHHCCCCCCCCCCCCHHHHHHHCCCCCHHHHEEEE
IVYTQIEEYDLAAENFDKACTMEYPEACESSKILKQWRTEVAEYEAYLARLAEQKAAINA
EEEEEHHHHHCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIASSGHDAALSAALNDYRSAELAEFVTGQAGSLSGFSTNNLYVVSYWFAGQATGAAADR
HHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCCCCCHHHH
ELASRGTGLEGTFGEGTNTPGTAAARYQAAYGSSPPSYTSASPASSAPPMKSVADIKAAT
HHHHCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
RDRYRWAHCTMSGSNTSAKVCQ
HCCEEEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]