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The map label for this gene is xseA [H]

Identifier: 114797378

GI number: 114797378

Start: 937061

End: 938488

Strand: Reverse

Name: xseA [H]

Synonym: HNE_0920

Alternate gene names: 114797378

Gene position: 938488-937061 (Counterclockwise)

Preceding gene: 114799375

Following gene: 114799890

Centisome position: 25.33

GC content: 66.67

Gene sequence:

>1428_bases
ATGGGCCAGCCGGTCCAGAACCAGCCCATGCCTGACTCGCCCACGACCAATCACCCTGAGCTCACCGTTTCGGAACTCGC
CGCGAGCCTGAAGCGGACGATTGAGACCAATTACGATCAGGTGACCGTGCGCGGCGAACTTGGCCGGGTGACGATTGCCA
AATCCGGCCACATGTATGCCGACCTAAAGGACGACAAGGCGGTGCTCAACACCATCATGTGGCGCGGGCAGGTCGACCGG
CTGACCTTCCGGCCTGAGGAAGGCCTGGAAGTGGTCGCCACAGGGCGCCTCTCCACCTATGAGGGCCGCTCCGCCTATCA
GATGATCGCCAGCACGATGCGGCCCGCCGGGGCGGGCGCGCTGATGCAGCTGCTAGAAGAGCGCAAGAAAAAGCTCGCGG
CGGAGGGCCTGTTCGATCAGGCCCACAAGAAGCCGATCCCCTATATGCCGCGCACCATCGGGGTGATCACTTCCCCCACT
GGCGCGGTGATCCGGGACATTCTGCACCGGATTCGCGAGCGGTTTCCCGTCCGCGTCATCGTCTGGCCGGCTCTGGTTCA
GGGCGAGCAGGCGGCAAGCCAAGTGACTGCCGGCATCCGGGGGTTCAACGCGATGACGGGGGCGGATCGGCCCGATGTGC
TGATCGTGGCGCGGGGCGGCGGGTCGATTGAAGACCTTTGGCCGTTCAATGAGGAGGTGGTCGTGCGGGCCGCTTTCGAG
AGTGAAATCCCTTTGATTTCAGCGGTTGGGCACGAGACCGATACCACGCTGATCGATTACGTTTCCGACCGGCGGGCGCC
GACGCCCACAGGCGCAGCCGAGATCGCCGTGCCGGTGCGCACCGAGCTGATGCTCGGCATTGAGGAATCCGGCCAGCGCC
TGAAACGCGCCCTCACCCGCGCCCTTTCCCGGTCCCGCGACAAGCTGGCCGCCGCGCGCCTGCCCCGGCCAGAAAGCCTT
TTGCAATCAAAGCGCCAGCGGCTGGACTTCGCCTCCGCCAGCCTGCCCCGCGCGGCCCTGGCGCTGACCCAGCGGGCGCG
CCTCAAACTCTCCCGCCTGCAGTTGTCACCGGCCACGCTGAAGGCGGAAATCCGCGGCCAGCGCCAGCGTCTGCGCGACA
CCGCCGTGCGCGCGCGGCCGGCCCTGATGCGCCTGATCGACCAGAAGAAGGCAGCGCTGACCTCCGAAGGCAAACTGCTC
GAAACCCTGTCCTATCAGGCCACGCTGAAACGCGGCTATGTGATCGTGCGCGACACTGGCGGGCAATTGGTGCGCAACGC
CGCGCAGGCGCAGACCCTCGACACGCTGCGCGTGACCTTTGCTGACGGCGATATTACGGCCGCCCCCTTTGAAGGCGAAA
CGCCCCCGCCGGCCCCCAAACCCAAGCCCGCCCCCCGCCGGAAAGGGGAGCAGGGCAACCTGTTCTGA

Upstream 100 bases:

>100_bases
CCCGCGTGCGATATGTATTGAAAACAGTTCTGCTGACAGGCGTACGCCTTGGCAGATCAACGCGCAAGGCTGGCCTTGGC
GGAGGCGCCATCTTGCCCTC

Downstream 100 bases:

>100_bases
TACCCCTCTTCGGGGGCATTACGGACCCGCTTTCCTTGCCTAGGATCATCGATGCATCCGGCTTCGACCGGATTCCCGAC
ATGGTTCAGCAACAAGGAGG

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 475; Mature: 474

Protein sequence:

>475_residues
MGQPVQNQPMPDSPTTNHPELTVSELAASLKRTIETNYDQVTVRGELGRVTIAKSGHMYADLKDDKAVLNTIMWRGQVDR
LTFRPEEGLEVVATGRLSTYEGRSAYQMIASTMRPAGAGALMQLLEERKKKLAAEGLFDQAHKKPIPYMPRTIGVITSPT
GAVIRDILHRIRERFPVRVIVWPALVQGEQAASQVTAGIRGFNAMTGADRPDVLIVARGGGSIEDLWPFNEEVVVRAAFE
SEIPLISAVGHETDTTLIDYVSDRRAPTPTGAAEIAVPVRTELMLGIEESGQRLKRALTRALSRSRDKLAAARLPRPESL
LQSKRQRLDFASASLPRAALALTQRARLKLSRLQLSPATLKAEIRGQRQRLRDTAVRARPALMRLIDQKKAALTSEGKLL
ETLSYQATLKRGYVIVRDTGGQLVRNAAQAQTLDTLRVTFADGDITAAPFEGETPPPAPKPKPAPRRKGEQGNLF

Sequences:

>Translated_475_residues
MGQPVQNQPMPDSPTTNHPELTVSELAASLKRTIETNYDQVTVRGELGRVTIAKSGHMYADLKDDKAVLNTIMWRGQVDR
LTFRPEEGLEVVATGRLSTYEGRSAYQMIASTMRPAGAGALMQLLEERKKKLAAEGLFDQAHKKPIPYMPRTIGVITSPT
GAVIRDILHRIRERFPVRVIVWPALVQGEQAASQVTAGIRGFNAMTGADRPDVLIVARGGGSIEDLWPFNEEVVVRAAFE
SEIPLISAVGHETDTTLIDYVSDRRAPTPTGAAEIAVPVRTELMLGIEESGQRLKRALTRALSRSRDKLAAARLPRPESL
LQSKRQRLDFASASLPRAALALTQRARLKLSRLQLSPATLKAEIRGQRQRLRDTAVRARPALMRLIDQKKAALTSEGKLL
ETLSYQATLKRGYVIVRDTGGQLVRNAAQAQTLDTLRVTFADGDITAAPFEGETPPPAPKPKPAPRRKGEQGNLF
>Mature_474_residues
GQPVQNQPMPDSPTTNHPELTVSELAASLKRTIETNYDQVTVRGELGRVTIAKSGHMYADLKDDKAVLNTIMWRGQVDRL
TFRPEEGLEVVATGRLSTYEGRSAYQMIASTMRPAGAGALMQLLEERKKKLAAEGLFDQAHKKPIPYMPRTIGVITSPTG
AVIRDILHRIRERFPVRVIVWPALVQGEQAASQVTAGIRGFNAMTGADRPDVLIVARGGGSIEDLWPFNEEVVVRAAFES
EIPLISAVGHETDTTLIDYVSDRRAPTPTGAAEIAVPVRTELMLGIEESGQRLKRALTRALSRSRDKLAAARLPRPESLL
QSKRQRLDFASASLPRAALALTQRARLKLSRLQLSPATLKAEIRGQRQRLRDTAVRARPALMRLIDQKKAALTSEGKLLE
TLSYQATLKRGYVIVRDTGGQLVRNAAQAQTLDTLRVTFADGDITAAPFEGETPPPAPKPKPAPRRKGEQGNLF

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=441, Percent_Identity=38.5487528344671, Blast_Score=271, Evalue=7e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579 [H]

Pfam domain/function: PF02601 Exonuc_VII_L [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 52157; Mature: 52026

Theoretical pI: Translated: 10.73; Mature: 10.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGQPVQNQPMPDSPTTNHPELTVSELAASLKRTIETNYDQVTVRGELGRVTIAKSGHMYA
CCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHCCCCEEEEEECCCEEEEEECCCEEE
DLKDDKAVLNTIMWRGQVDRLTFRPEEGLEVVATGRLSTYEGRSAYQMIASTMRPAGAGA
ECCCHHHHHHHHHHCCCCCCEEECCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCHHH
LMQLLEERKKKLAAEGLFDQAHKKPIPYMPRTIGVITSPTGAVIRDILHRIRERFPVRVI
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHCCEEEE
VWPALVQGEQAASQVTAGIRGFNAMTGADRPDVLIVARGGGSIEDLWPFNEEVVVRAAFE
EECHHHCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCHHCCCCCHHHEEEEECC
SEIPLISAVGHETDTTLIDYVSDRRAPTPTGAAEIAVPVRTELMLGIEESGQRLKRALTR
CCCCEEEECCCCCCCHHHHHHHCCCCCCCCCCCEEEEEEHHHHEECHHHHHHHHHHHHHH
ALSRSRDKLAAARLPRPESLLQSKRQRLDFASASLPRAALALTQRARLKLSRLQLSPATL
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHH
KAEIRGQRQRLRDTAVRARPALMRLIDQKKAALTSEGKLLETLSYQATLKRGYVIVRDTG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCEEEEECCC
GQLVRNAAQAQTLDTLRVTFADGDITAAPFEGETPPPAPKPKPAPRRKGEQGNLF
HHHHHHHHHHHHHEEEEEEEECCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
GQPVQNQPMPDSPTTNHPELTVSELAASLKRTIETNYDQVTVRGELGRVTIAKSGHMYA
CCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHCCCCEEEEEECCCEEEEEECCCEEE
DLKDDKAVLNTIMWRGQVDRLTFRPEEGLEVVATGRLSTYEGRSAYQMIASTMRPAGAGA
ECCCHHHHHHHHHHCCCCCCEEECCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCHHH
LMQLLEERKKKLAAEGLFDQAHKKPIPYMPRTIGVITSPTGAVIRDILHRIRERFPVRVI
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHCCEEEE
VWPALVQGEQAASQVTAGIRGFNAMTGADRPDVLIVARGGGSIEDLWPFNEEVVVRAAFE
EECHHHCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCHHCCCCCHHHEEEEECC
SEIPLISAVGHETDTTLIDYVSDRRAPTPTGAAEIAVPVRTELMLGIEESGQRLKRALTR
CCCCEEEECCCCCCCHHHHHHHCCCCCCCCCCCEEEEEEHHHHEECHHHHHHHHHHHHHH
ALSRSRDKLAAARLPRPESLLQSKRQRLDFASASLPRAALALTQRARLKLSRLQLSPATL
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHH
KAEIRGQRQRLRDTAVRARPALMRLIDQKKAALTSEGKLLETLSYQATLKRGYVIVRDTG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCEEEEECCC
GQLVRNAAQAQTLDTLRVTFADGDITAAPFEGETPPPAPKPKPAPRRKGEQGNLF
HHHHHHHHHHHHHEEEEEEEECCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA