Click here to switch to the map view.

The map label for this gene is prsA [H]

Identifier: 114799826

GI number: 114799826

Start: 3349890

End: 3350801

Strand: Reverse

Name: prsA [H]

Synonym: HNE_3175

Alternate gene names: 114799826

Gene position: 3350801-3349890 (Counterclockwise)

Preceding gene: 114797168

Following gene: 114798075

Centisome position: 90.44

GC content: 63.05

Gene sequence:

>912_bases
ATGATCCGCAGGTGTGCTGATTTTACAGCTTTTTGCGCCGTTATGGCCGCTTTGACGCTGGCAGGGTGCTCGCAGGAAGG
CTTTCAGCTGGAAGAACCCAGGGAGGTCAGCCGCGAGGTGGCCGCCACGGTGAATGGCGAGGCAATTTACACCGCCGATG
TCGAGGTTGAGGCAGTCGCGCGCGGGCTGGTGGTCTCCGGCGCGTCGCTGCGGGCGGAGGACGAGGCCTACAAACAGGTG
CTCGACCAGCTGATCGACCAGAAGCTGATGGCACAGGAGGCCAAGCGCCTGGGGCTGGAGAAAGACCCCGCCGGAATGCG
CCGTCTGGAGATGGCGCAGGAGCGCATCATGGGGAACCTTCTTGTGGAAAGCGTCGTGGCCGAGCAGGTCACCGATGAGA
TGATCGACCGGATGTATGCCGAGCAGGTGCGGTTGCAGCAGGTGAATGATGAAGTCTCGGTGGCGCATATTGTGACGGAT
ACCGAGGAAGAGGCCGAGGCCGTCTGGCTGCGCGTGCAGGCGGGCGAGGCGTTCGAGAGCCTGGTGTTCAACCATTCCAA
TGACAGCGCCACGCGGATGGAAAATGGCGATCTGGGGTTTGTATCGCCCAATGATCTGCCCGATCCCTATCCGGTGGTGA
TTGCCAATACGCCGGTGGGGGAGGTGGCCCCGCCGTTTGAGGCAGAGGGCAGCTGGCGGATCGTGAAGGTCAAGGACCGG
CGCACCGAGCCGCCCAAGACGCGCGACGAGATGCGCCCGGAAATCGCGACCTTCCTGACGCTGAGCGAGGTGAGCCGCAT
TCTGCGCCGCCTGCGCACCGAGGCACGTATTGAGGAAGGCGGCGGAGCAGATTATGCGCCGGAAAACGCGCCCGAGCCTT
CGGCCAAAGCCCTCACTGGAGATGAATTGTGA

Upstream 100 bases:

>100_bases
GCCATTACCGGATGAAACCACTCGACCAGCGCGCGGGGCAGACTTAAGAACGCCGCCAAGGGGTGTCAATGCGGCGCCTT
CAGCCCAGGAGGGGAAGCCG

Downstream 100 bases:

>100_bases
ACCTTACCCCTTCGCCCTTTGCGCCGGCCAGCTTTCCGGCGCTTCCTGCTGCGCGCGGCCTGAAGGCGGCCTCTGGCAGC
CGTGGCTTTTATGCGCGCCG

Product: peptidyl-prolyl cis-trans isomerase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MIRRCADFTAFCAVMAALTLAGCSQEGFQLEEPREVSREVAATVNGEAIYTADVEVEAVARGLVVSGASLRAEDEAYKQV
LDQLIDQKLMAQEAKRLGLEKDPAGMRRLEMAQERIMGNLLVESVVAEQVTDEMIDRMYAEQVRLQQVNDEVSVAHIVTD
TEEEAEAVWLRVQAGEAFESLVFNHSNDSATRMENGDLGFVSPNDLPDPYPVVIANTPVGEVAPPFEAEGSWRIVKVKDR
RTEPPKTRDEMRPEIATFLTLSEVSRILRRLRTEARIEEGGGADYAPENAPEPSAKALTGDEL

Sequences:

>Translated_303_residues
MIRRCADFTAFCAVMAALTLAGCSQEGFQLEEPREVSREVAATVNGEAIYTADVEVEAVARGLVVSGASLRAEDEAYKQV
LDQLIDQKLMAQEAKRLGLEKDPAGMRRLEMAQERIMGNLLVESVVAEQVTDEMIDRMYAEQVRLQQVNDEVSVAHIVTD
TEEEAEAVWLRVQAGEAFESLVFNHSNDSATRMENGDLGFVSPNDLPDPYPVVIANTPVGEVAPPFEAEGSWRIVKVKDR
RTEPPKTRDEMRPEIATFLTLSEVSRILRRLRTEARIEEGGGADYAPENAPEPSAKALTGDEL
>Mature_303_residues
MIRRCADFTAFCAVMAALTLAGCSQEGFQLEEPREVSREVAATVNGEAIYTADVEVEAVARGLVVSGASLRAEDEAYKQV
LDQLIDQKLMAQEAKRLGLEKDPAGMRRLEMAQERIMGNLLVESVVAEQVTDEMIDRMYAEQVRLQQVNDEVSVAHIVTD
TEEEAEAVWLRVQAGEAFESLVFNHSNDSATRMENGDLGFVSPNDLPDPYPVVIANTPVGEVAPPFEAEGSWRIVKVKDR
RTEPPKTRDEMRPEIATFLTLSEVSRILRRLRTEARIEEGGGADYAPENAPEPSAKALTGDEL

Specific function: Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023059
- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 33452; Mature: 33452

Theoretical pI: Translated: 4.21; Mature: 4.21

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRRCADFTAFCAVMAALTLAGCSQEGFQLEEPREVSREVAATVNGEAIYTADVEVEAVA
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCHHHHH
RGLVVSGASLRAEDEAYKQVLDQLIDQKLMAQEAKRLGLEKDPAGMRRLEMAQERIMGNL
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
LVESVVAEQVTDEMIDRMYAEQVRLQQVNDEVSVAHIVTDTEEEAEAVWLRVQAGEAFES
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHCCEEEEEEECCHHHHH
LVFNHSNDSATRMENGDLGFVSPNDLPDPYPVVIANTPVGEVAPPFEAEGSWRIVKVKDR
HHHCCCCCCHHCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCEEEEEEECC
RTEPPKTRDEMRPEIATFLTLSEVSRILRRLRTEARIEEGGGADYAPENAPEPSAKALTG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
DEL
CCC
>Mature Secondary Structure
MIRRCADFTAFCAVMAALTLAGCSQEGFQLEEPREVSREVAATVNGEAIYTADVEVEAVA
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCHHHHH
RGLVVSGASLRAEDEAYKQVLDQLIDQKLMAQEAKRLGLEKDPAGMRRLEMAQERIMGNL
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
LVESVVAEQVTDEMIDRMYAEQVRLQQVNDEVSVAHIVTDTEEEAEAVWLRVQAGEAFES
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHCCEEEEEEECCHHHHH
LVFNHSNDSATRMENGDLGFVSPNDLPDPYPVVIANTPVGEVAPPFEAEGSWRIVKVKDR
HHHCCCCCCHHCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCEEEEEEECC
RTEPPKTRDEMRPEIATFLTLSEVSRILRRLRTEARIEEGGGADYAPENAPEPSAKALTG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
DEL
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]