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The map label for this gene is qor [C]

Identifier: 114799729

GI number: 114799729

Start: 2543615

End: 2544595

Strand: Direct

Name: qor [C]

Synonym: HNE_2433

Alternate gene names: 114799729

Gene position: 2543615-2544595 (Clockwise)

Preceding gene: 114799799

Following gene: 114798242

Centisome position: 68.65

GC content: 64.63

Gene sequence:

>981_bases
ATGAAAGCTGCCGTCGCAGACAGCCTTGAGTCCCTTGAAAGCTACAGCCTGAAAGAGGTGGAGATGCCTGGCGCCGGGCC
GGGTCAGGTGCTGATCCGGGTAATGGCCTGCGGCGTTGGCTATGTGGATTCTCTGGTGGCGCTGGGGCGGTATCAGGTGA
AGCCGCCCGTGCCCCACACGCCGGGTCAGGAAGTGGCCGGAACGGTGGAAGCTGTTGGCGAAGGCGTCAGCCATGTTGCG
CCCGGAGACCGGGTGATGACGATGACGGCGAAGGGCTTTGCCGAGTTTGCCGTGGCGGCTGCGCCGATGGTGGTGAAACT
TCCCGAGGCGCTGAGCTTTGCCGAAGGCGCCAGCTTGCCACTGAACTACATCACGGCAATGCACGCCCTGAAGGATCGCG
GCGCAGTTGCCGAGGGCGAAACGGTTCTGGTGTTCGGCGCCGCAGGCGGAGTGGGCTCGGCTGGGGTGCAGGTGGCCAAG
GCGCTGGGCGCGCGCGTGATCGCGGCGGCCTCAACCGAGGAGAAGCGGGCCTTTGCGCTGGCGCATGGCGCAGACCTCGC
GATTGATACGTCCCCGGAAGGTTGGCGAGACCGGCTGAAGGAACTGACCGGCGGAAAGGGGCCAAACGTGATCCTTGATC
CGGTGTGCGGGCCGCTGTTTGAGCCGGCATTCCGGTCTCTCGCCTGGCGCGGGCGCCACCTTGTTGTGGGGTTTGTGGGC
GGGCCGATCCCTGCTCTGCCCTCAAACCTTACTCTGATGAAAGGCGCAGCGCTGCTGGGCGTGGATGTCCGCCAGTATCT
GCAATACGAGACAAAGCGCGCCATCGGCGACCTCCATCAGCTGGCGACTTGGGCGAGCGAAGGTAAGATCAAGCCGCCTG
TCGGCGCGGTTTATCCGTTCGAGCAGTTTGGCGAGGCGATGGTGTCTGCGCTTTCTGGCCAGGGAACCGGTAAGGTCGTG
CTCGACATTTCCGGGAGCTGA

Upstream 100 bases:

>100_bases
GACTTTCCCTTCCGTCGGGGCTGGCCAATGGGGCTGGCGCCATGCTTTGACTGGCGCCGACAAGACCTGACCCAATCCGG
ACACGTGGAGACATCGACCA

Downstream 100 bases:

>100_bases
CGGGGCGGTTTACGTCGCGCGCTGCCTGAACCTTACCGCGAGGTGAATTTTCTCTTAATTCCGGCCTGACAATTACTGCC
AGCTACTGAGGCTGCTGTTC

Product: putative quinone oxidoreductase

Products: NA

Alternate protein names: ADH-HT [H]

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MKAAVADSLESLESYSLKEVEMPGAGPGQVLIRVMACGVGYVDSLVALGRYQVKPPVPHTPGQEVAGTVEAVGEGVSHVA
PGDRVMTMTAKGFAEFAVAAAPMVVKLPEALSFAEGASLPLNYITAMHALKDRGAVAEGETVLVFGAAGGVGSAGVQVAK
ALGARVIAAASTEEKRAFALAHGADLAIDTSPEGWRDRLKELTGGKGPNVILDPVCGPLFEPAFRSLAWRGRHLVVGFVG
GPIPALPSNLTLMKGAALLGVDVRQYLQYETKRAIGDLHQLATWASEGKIKPPVGAVYPFEQFGEAMVSALSGQGTGKVV
LDISGS

Sequences:

>Translated_326_residues
MKAAVADSLESLESYSLKEVEMPGAGPGQVLIRVMACGVGYVDSLVALGRYQVKPPVPHTPGQEVAGTVEAVGEGVSHVA
PGDRVMTMTAKGFAEFAVAAAPMVVKLPEALSFAEGASLPLNYITAMHALKDRGAVAEGETVLVFGAAGGVGSAGVQVAK
ALGARVIAAASTEEKRAFALAHGADLAIDTSPEGWRDRLKELTGGKGPNVILDPVCGPLFEPAFRSLAWRGRHLVVGFVG
GPIPALPSNLTLMKGAALLGVDVRQYLQYETKRAIGDLHQLATWASEGKIKPPVGAVYPFEQFGEAMVSALSGQGTGKVV
LDISGS
>Mature_326_residues
MKAAVADSLESLESYSLKEVEMPGAGPGQVLIRVMACGVGYVDSLVALGRYQVKPPVPHTPGQEVAGTVEAVGEGVSHVA
PGDRVMTMTAKGFAEFAVAAAPMVVKLPEALSFAEGASLPLNYITAMHALKDRGAVAEGETVLVFGAAGGVGSAGVQVAK
ALGARVIAAASTEEKRAFALAHGADLAIDTSPEGWRDRLKELTGGKGPNVILDPVCGPLFEPAFRSLAWRGRHLVVGFVG
GPIPALPSNLTLMKGAALLGVDVRQYLQYETKRAIGDLHQLATWASEGKIKPPVGAVYPFEQFGEAMVSALSGQGTGKVV
LDISGS

Specific function: Thermophilic NAD(+)-dependent alcohol dehydrogenase. Bears mainly an ethanol-dehydrogenase activity [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI194239674, Length=306, Percent_Identity=36.6013071895425, Blast_Score=177, Evalue=1e-44,
Organism=Homo sapiens, GI13236495, Length=306, Percent_Identity=36.6013071895425, Blast_Score=177, Evalue=1e-44,
Organism=Homo sapiens, GI194239676, Length=306, Percent_Identity=34.3137254901961, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI18379349, Length=310, Percent_Identity=32.258064516129, Blast_Score=138, Evalue=6e-33,
Organism=Homo sapiens, GI24308257, Length=355, Percent_Identity=29.0140845070423, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI22538446, Length=318, Percent_Identity=27.3584905660377, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI22538444, Length=318, Percent_Identity=27.3584905660377, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI28557745, Length=328, Percent_Identity=31.0975609756098, Blast_Score=101, Evalue=8e-22,
Organism=Homo sapiens, GI41872631, Length=310, Percent_Identity=29.0322580645161, Blast_Score=88, Evalue=8e-18,
Organism=Homo sapiens, GI197927207, Length=196, Percent_Identity=32.1428571428571, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI47519420, Length=332, Percent_Identity=27.4096385542169, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI67078404, Length=317, Percent_Identity=24.9211356466877, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1790485, Length=244, Percent_Identity=33.1967213114754, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI226510941, Length=335, Percent_Identity=27.1641791044776, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI87081918, Length=331, Percent_Identity=25.9818731117825, Blast_Score=65, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17507255, Length=326, Percent_Identity=30.6748466257669, Blast_Score=116, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI71987554, Length=375, Percent_Identity=28.5333333333333, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI212642053, Length=308, Percent_Identity=25.974025974026, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17536829, Length=315, Percent_Identity=26.6666666666667, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6319520, Length=332, Percent_Identity=28.3132530120482, Blast_Score=117, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6324486, Length=347, Percent_Identity=25.3602305475504, Blast_Score=64, Evalue=4e-11,
Organism=Drosophila melanogaster, GI19920632, Length=250, Percent_Identity=28.4, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24581345, Length=323, Percent_Identity=25.6965944272446, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI221330659, Length=250, Percent_Identity=28.4, Blast_Score=86, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 33622; Mature: 33622

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS01162 QOR_ZETA_CRYSTAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAAVADSLESLESYSLKEVEMPGAGPGQVLIRVMACGVGYVDSLVALGRYQVKPPVPHT
CCCHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHCCHHHHHHHHHCCEECCCCCCCC
PGQEVAGTVEAVGEGVSHVAPGDRVMTMTAKGFAEFAVAAAPMVVKLPEALSFAEGASLP
CCHHHHHHHHHHHCCHHHCCCCCEEEEEEHHHHHHHHHHHCCHHEECHHHHHHHCCCCCC
LNYITAMHALKDRGAVAEGETVLVFGAAGGVGSAGVQVAKALGARVIAAASTEEKRAFAL
HHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHEEEECCCCHHHEEEE
AHGADLAIDTSPEGWRDRLKELTGGKGPNVILDPVCGPLFEPAFRSLAWRGRHLVVGFVG
ECCCCEEEECCCHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHCCCEEEEEECC
GPIPALPSNLTLMKGAALLGVDVRQYLQYETKRAIGDLHQLATWASEGKIKPPVGAVYPF
CCCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCH
EQFGEAMVSALSGQGTGKVVLDISGS
HHHHHHHHHHHCCCCCCEEEEEECCC
>Mature Secondary Structure
MKAAVADSLESLESYSLKEVEMPGAGPGQVLIRVMACGVGYVDSLVALGRYQVKPPVPHT
CCCHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHCCHHHHHHHHHCCEECCCCCCCC
PGQEVAGTVEAVGEGVSHVAPGDRVMTMTAKGFAEFAVAAAPMVVKLPEALSFAEGASLP
CCHHHHHHHHHHHCCHHHCCCCCEEEEEEHHHHHHHHHHHCCHHEECHHHHHHHCCCCCC
LNYITAMHALKDRGAVAEGETVLVFGAAGGVGSAGVQVAKALGARVIAAASTEEKRAFAL
HHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHEEEECCCCHHHEEEE
AHGADLAIDTSPEGWRDRLKELTGGKGPNVILDPVCGPLFEPAFRSLAWRGRHLVVGFVG
ECCCCEEEECCCHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHCCCEEEEEECC
GPIPALPSNLTLMKGAALLGVDVRQYLQYETKRAIGDLHQLATWASEGKIKPPVGAVYPF
CCCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCH
EQFGEAMVSALSGQGTGKVVLDISGS
HHHHHHHHHHHCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8020473 [H]