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The map label for this gene is nahD [H]

Identifier: 114799700

GI number: 114799700

Start: 1002664

End: 1003272

Strand: Reverse

Name: nahD [H]

Synonym: HNE_0987

Alternate gene names: 114799700

Gene position: 1003272-1002664 (Counterclockwise)

Preceding gene: 114799094

Following gene: 114797492

Centisome position: 27.08

GC content: 68.64

Gene sequence:

>609_bases
ATGCGCCCGCCTGCCCCGATCGAATTCTGGTTCGATTTTTCTTCCGGCTATGCCTATTTCGCCGCTCAGGAAATTGACGC
GCTCGGCGCCCGTGTCGGCCGCCCCATCCTCTGGCGCCCCTATATGCTGGGCACGGCGTTCAAGGTCACCGGCATGCGCG
GCCTCTCTGCCACACCGGTAAAGGGCGGCTATGCCCGCCACGACTGGCAGCGCGCGGCCCGTAAGCTCGGGGTCCCCTTC
GCCCCGCCTGCCGATCACCCGAAAATCGCCCTGCCCGCCACCCGCGCCTTCTACTGGATAGAGGCCCACCATCCCGGCCA
GGAACGCCCCTTCGCCCGCGAGATCTTCGCCCGCTACTATTCCGGCGCGCTCGATAGCAGCGACCCCGATGCCATCGCCG
CCCTCGCCGGCCCGCTCGGGCTGGACGCAGCCGCCCTGCGCGAAGGCCTCGAAACCCCCGCCATCAAGGACCATGCCCGC
GCCACCAGCGAAGCGGCCATCGCGCGCGGCATCTTCGGCTCGCCCTTCTTCGTGATTGATGAGGAACCCTTCTGGGGCTG
GGACCGTCTGCCCATGCTCGAGGACTGGGCCCGCACGGGCGGCTGGTAA

Upstream 100 bases:

>100_bases
TGTCAAACTTGACCACGCGGCACTCAAGGCCATCGGTTGACGTTTATCCGCTTTGCCCCGAGGTAAGCCGTATGGCCCTT
TCTGCCGGAGGAATGCCTGA

Downstream 100 bases:

>100_bases
GCCTATGGACCCCGCCGCCGCCATCCTCTCCTTCTCCGTCGCCGCCCTGCTGCTGACGCTGACGCCCGGCCTCGATACCG
CGCTCGTCCTGCGCACAGCC

Product: putative 2-hydroxychromene-2-carboxylate isomerase

Products: NA

Alternate protein names: HCCA isomerase [H]

Number of amino acids: Translated: 202; Mature: 202

Protein sequence:

>202_residues
MRPPAPIEFWFDFSSGYAYFAAQEIDALGARVGRPILWRPYMLGTAFKVTGMRGLSATPVKGGYARHDWQRAARKLGVPF
APPADHPKIALPATRAFYWIEAHHPGQERPFAREIFARYYSGALDSSDPDAIAALAGPLGLDAAALREGLETPAIKDHAR
ATSEAAIARGIFGSPFFVIDEEPFWGWDRLPMLEDWARTGGW

Sequences:

>Translated_202_residues
MRPPAPIEFWFDFSSGYAYFAAQEIDALGARVGRPILWRPYMLGTAFKVTGMRGLSATPVKGGYARHDWQRAARKLGVPF
APPADHPKIALPATRAFYWIEAHHPGQERPFAREIFARYYSGALDSSDPDAIAALAGPLGLDAAALREGLETPAIKDHAR
ATSEAAIARGIFGSPFFVIDEEPFWGWDRLPMLEDWARTGGW
>Mature_202_residues
MRPPAPIEFWFDFSSGYAYFAAQEIDALGARVGRPILWRPYMLGTAFKVTGMRGLSATPVKGGYARHDWQRAARKLGVPF
APPADHPKIALPATRAFYWIEAHHPGQERPFAREIFARYYSGALDSSDPDAIAALAGPLGLDAAALREGLETPAIKDHAR
ATSEAAIARGIFGSPFFVIDEEPFWGWDRLPMLEDWARTGGW

Specific function: Catalyzes the isomerization of 2-hydroxychromene-2- carboxylate (HCCA) to trans-O-hydroxybenzylidenepyruvate (THBPA). The reaction is reversible [H]

COG id: COG3917

COG function: function code Q; 2-hydroxychromene-2-carboxylate isomerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI7705704, Length=202, Percent_Identity=26.2376237623762, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001853
- InterPro:   IPR014440
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01323 DSBA [H]

EC number: NA

Molecular weight: Translated: 22330; Mature: 22330

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPPAPIEFWFDFSSGYAYFAAQEIDALGARVGRPILWRPYMLGTAFKVTGMRGLSATPV
CCCCCCEEEEEECCCCEEEEHHHHHHHHHHHHCCCEEECCHHHCCEEEECCCCCCCCCCC
KGGYARHDWQRAARKLGVPFAPPADHPKIALPATRAFYWIEAHHPGQERPFAREIFARYY
CCCCHHHHHHHHHHHCCCCCCCCCCCCEEECCCCEEEEEEEECCCCCCCCHHHHHHHHHH
SGALDSSDPDAIAALAGPLGLDAAALREGLETPAIKDHARATSEAAIARGIFGSPFFVID
CCCCCCCCCHHHHHHHCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEE
EEPFWGWDRLPMLEDWARTGGW
CCCCCCCCCCCHHHHHHHCCCC
>Mature Secondary Structure
MRPPAPIEFWFDFSSGYAYFAAQEIDALGARVGRPILWRPYMLGTAFKVTGMRGLSATPV
CCCCCCEEEEEECCCCEEEEHHHHHHHHHHHHCCCEEECCHHHCCEEEECCCCCCCCCCC
KGGYARHDWQRAARKLGVPFAPPADHPKIALPATRAFYWIEAHHPGQERPFAREIFARYY
CCCCHHHHHHHHHHHCCCCCCCCCCCCEEECCCCEEEEEEEECCCCCCCCHHHHHHHHHH
SGALDSSDPDAIAALAGPLGLDAAALREGLETPAIKDHARATSEAAIARGIFGSPFFVID
CCCCCCCCCHHHHHHHCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEE
EEPFWGWDRLPMLEDWARTGGW
CCCCCCCCCCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8002605; 1447127 [H]