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The map label for this gene is leuE [H]

Identifier: 114797492

GI number: 114797492

Start: 1002012

End: 1002659

Strand: Reverse

Name: leuE [H]

Synonym: HNE_0986

Alternate gene names: 114797492

Gene position: 1002659-1002012 (Counterclockwise)

Preceding gene: 114799700

Following gene: 114798230

Centisome position: 27.06

GC content: 69.75

Gene sequence:

>648_bases
ATGGACCCCGCCGCCGCCATCCTCTCCTTCTCCGTCGCCGCCCTGCTGCTGACGCTGACGCCCGGCCTCGATACCGCGCT
CGTCCTGCGCACAGCCACCGTCGAAAGCCCCCGCCGGGGCATGATCGCAGGCGCCGGCGTCACGCTCGGCGTCCTCGTCT
GGGGCATTGCGGCCGCCGCCGGTGTCGGCTCCCTCGCCGCCGCCTCCCCGCTCGCCTACCAGGCCCTGCGCATCGCGGGC
GCTCTCTATGTCCTCTGGCTCGGCGGCCAGATGATCTGGTCAGCATACCAGACGCTCCGCCACCACAAAGCAGCAGATAA
AGTCAGCGCGCAAACCGCCCGCCAGCCCAACTGGTTCCTCCGGGGTCTGACGACTAATCTGCTCAATCCCAAAGTTGGCC
TCTTCTACGCAAGCTTCCTGCCGCAATTCCTCCCGAGAGACCATTTCGGCCCAGCCGGCCTCGTCGCCTTCGGCGCCGGC
CTCGCCCTCATCCATTGCGCCTTTGGCCTCGCCTTCTTTGCCCTCATCACCAGCGCCGCCGCCCGCGCCAGCCGCTTCCT
CGCCCGCCCCGGCGTGCGCGGGGGCATCGAGGGGCTCACCGGCCTCGTCCTCTGCGCCGCCGCCCTCCTGCTGCTGATTG
CGCATTAG

Upstream 100 bases:

>100_bases
TTCGGCTCGCCCTTCTTCGTGATTGATGAGGAACCCTTCTGGGGCTGGGACCGTCTGCCCATGCTCGAGGACTGGGCCCG
CACGGGCGGCTGGTAAGCCT

Downstream 100 bases:

>100_bases
GCGCCGGCTCAGGAGCCTCAAAAAAAATCCTGTTGCCCCCCGCCTGAAGAAGTGGCACGAATAATGCCAATACCTGAAAT
GCCAAGGCTGGGGGCAAGAG

Product: LysE family translocator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MDPAAAILSFSVAALLLTLTPGLDTALVLRTATVESPRRGMIAGAGVTLGVLVWGIAAAAGVGSLAAASPLAYQALRIAG
ALYVLWLGGQMIWSAYQTLRHHKAADKVSAQTARQPNWFLRGLTTNLLNPKVGLFYASFLPQFLPRDHFGPAGLVAFGAG
LALIHCAFGLAFFALITSAAARASRFLARPGVRGGIEGLTGLVLCAAALLLLIAH

Sequences:

>Translated_215_residues
MDPAAAILSFSVAALLLTLTPGLDTALVLRTATVESPRRGMIAGAGVTLGVLVWGIAAAAGVGSLAAASPLAYQALRIAG
ALYVLWLGGQMIWSAYQTLRHHKAADKVSAQTARQPNWFLRGLTTNLLNPKVGLFYASFLPQFLPRDHFGPAGLVAFGAG
LALIHCAFGLAFFALITSAAARASRFLARPGVRGGIEGLTGLVLCAAALLLLIAH
>Mature_215_residues
MDPAAAILSFSVAALLLTLTPGLDTALVLRTATVESPRRGMIAGAGVTLGVLVWGIAAAAGVGSLAAASPLAYQALRIAG
ALYVLWLGGQMIWSAYQTLRHHKAADKVSAQTARQPNWFLRGLTTNLLNPKVGLFYASFLPQFLPRDHFGPAGLVAFGAG
LALIHCAFGLAFFALITSAAARASRFLARPGVRGGIEGLTGLVLCAAALLLLIAH

Specific function: Exporter of leucine [H]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI1788099, Length=142, Percent_Identity=33.0985915492958, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI48994978, Length=145, Percent_Identity=28.9655172413793, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 22256; Mature: 22256

Theoretical pI: Translated: 11.08; Mature: 11.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDPAAAILSFSVAALLLTLTPGLDTALVLRTATVESPRRGMIAGAGVTLGVLVWGIAAAA
CCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCEECCHHHHHHHHHHHHHHH
GVGSLAAASPLAYQALRIAGALYVLWLGGQMIWSAYQTLRHHKAADKVSAQTARQPNWFL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
RGLTTNLLNPKVGLFYASFLPQFLPRDHFGPAGLVAFGAGLALIHCAFGLAFFALITSAA
HHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARASRFLARPGVRGGIEGLTGLVLCAAALLLLIAH
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDPAAAILSFSVAALLLTLTPGLDTALVLRTATVESPRRGMIAGAGVTLGVLVWGIAAAA
CCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCEECCHHHHHHHHHHHHHHH
GVGSLAAASPLAYQALRIAGALYVLWLGGQMIWSAYQTLRHHKAADKVSAQTARQPNWFL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
RGLTTNLLNPKVGLFYASFLPQFLPRDHFGPAGLVAFGAGLALIHCAFGLAFFALITSAA
HHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARASRFLARPGVRGGIEGLTGLVLCAAALLLLIAH
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA