Click here to switch to the map view.

The map label for this gene is yfkM [H]

Identifier: 114799641

GI number: 114799641

Start: 1082606

End: 1083232

Strand: Reverse

Name: yfkM [H]

Synonym: HNE_1075

Alternate gene names: 114799641

Gene position: 1083232-1082606 (Counterclockwise)

Preceding gene: 114797996

Following gene: 114798789

Centisome position: 29.24

GC content: 59.81

Gene sequence:

>627_bases
ATGAAAAAAGGCCGGAACCATCCGGCCTCCTCGGGAATTAACATCGGTAAGCCGTGCGCCCCATCAGTCAGATCAAAGGA
AACGTCCATGAAACTCAGCGGACGGAAAATCGCCATTCTCATCGCGCCCAGAGGATCAGAAGACTCTGAATTCACTGAGC
CCCGTAAAGCCGTCGAGGCCGAAGGCGCAGAAACCGTCATCATCAGCACGCAGCTCGGCAAAGCCGAGACGATGAAGGGC
GACCTTGACCCCGCAGGCCAGTATGATGTGGACGCGGTATTCAGCCAGGTCCACGTCGACGACTTTGACGCCCTCATCAT
CCCCGGCGGAACAGTCGGATCAGACAAACTCCGCGCCAGCCTCGATGCCGTCGCCTTCGTCAGCGCCTTCTTCCGCCAGT
CAAAGCCCGTCGCCGCCATCTGCCATGGCCCGTGGCTGATCGTCGAGGCCGGCGCCGCAAAGGGCAGAAAGCTGACATCC
TACAGCAGTCTGCGCACGGACATCCAGAACGCGGGCGGAGACTGGGTGGACGAGGAGGTCGTCGTCGACAATGGCCTGAT
CACCAGCCGCTCTCCAGATGACCTTCCTGCCTTCACCGCCCGGATCATTGAAGAATTTTCCGCTTGA

Upstream 100 bases:

>100_bases
CTCGCCGGACGGCGGTGGCGGGTGACGCCTGGTCCGGGCCATTGCGGCGAACATTTCTTCGCCCTTCGGGGGCATCCGGG
AAGGGCGCCGGGCAAGCGAG

Downstream 100 bases:

>100_bases
ATTTCCTGCCCGCGGTGTATGCTAATCCATCTCGAGATTGCATTTTGTTGACTGATCCCACCCCTGCCAGGAGGACCTTC
CCGTATGTCCGGAAGCCCTA

Product: PfpI family intracellular peptidase

Products: NA

Alternate protein names: GSP18 [H]

Number of amino acids: Translated: 208; Mature: 208

Protein sequence:

>208_residues
MKKGRNHPASSGINIGKPCAPSVRSKETSMKLSGRKIAILIAPRGSEDSEFTEPRKAVEAEGAETVIISTQLGKAETMKG
DLDPAGQYDVDAVFSQVHVDDFDALIIPGGTVGSDKLRASLDAVAFVSAFFRQSKPVAAICHGPWLIVEAGAAKGRKLTS
YSSLRTDIQNAGGDWVDEEVVVDNGLITSRSPDDLPAFTARIIEEFSA

Sequences:

>Translated_208_residues
MKKGRNHPASSGINIGKPCAPSVRSKETSMKLSGRKIAILIAPRGSEDSEFTEPRKAVEAEGAETVIISTQLGKAETMKG
DLDPAGQYDVDAVFSQVHVDDFDALIIPGGTVGSDKLRASLDAVAFVSAFFRQSKPVAAICHGPWLIVEAGAAKGRKLTS
YSSLRTDIQNAGGDWVDEEVVVDNGLITSRSPDDLPAFTARIIEEFSA
>Mature_208_residues
MKKGRNHPASSGINIGKPCAPSVRSKETSMKLSGRKIAILIAPRGSEDSEFTEPRKAVEAEGAETVIISTQLGKAETMKG
DLDPAGQYDVDAVFSQVHVDDFDALIIPGGTVGSDKLRASLDAVAFVSAFFRQSKPVAAICHGPWLIVEAGAAKGRKLTS
YSSLRTDIQNAGGDWVDEEVVVDNGLITSRSPDDLPAFTARIIEEFSA

Specific function: Functions in the protection against aldehyde-stress, possibly by degrading damaged proteins [H]

COG id: COG0693

COG function: function code R; Putative intracellular protease/amidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PfpI endopeptidase domain [H]

Homologues:

Organism=Escherichia coli, GI87082219, Length=166, Percent_Identity=44.578313253012, Blast_Score=123, Evalue=9e-30,
Organism=Drosophila melanogaster, GI28571932, Length=188, Percent_Identity=31.3829787234043, Blast_Score=75, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006286
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI [H]

EC number: NA

Molecular weight: Translated: 22102; Mature: 22102

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKGRNHPASSGINIGKPCAPSVRSKETSMKLSGRKIAILIAPRGSEDSEFTEPRKAVEA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCEEEEEEECCCCCCCCHHCHHHHHHC
EGAETVIISTQLGKAETMKGDLDPAGQYDVDAVFSQVHVDDFDALIIPGGTVGSDKLRAS
CCCCEEEEEECCCCCHHCCCCCCCCCCCCHHHHHHHHCCCCCCEEEECCCCCCHHHHHHH
LDAVAFVSAFFRQSKPVAAICHGPWLIVEAGAAKGRKLTSYSSLRTDIQNAGGDWVDEEV
HHHHHHHHHHHHCCCCEEEEECCCEEEEECCCCCCCEECHHHHHHHHHHHCCCCCCCCEE
VVDNGLITSRSPDDLPAFTARIIEEFSA
EECCCEECCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKGRNHPASSGINIGKPCAPSVRSKETSMKLSGRKIAILIAPRGSEDSEFTEPRKAVEA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCEEEEEEECCCCCCCCHHCHHHHHHC
EGAETVIISTQLGKAETMKGDLDPAGQYDVDAVFSQVHVDDFDALIIPGGTVGSDKLRAS
CCCCEEEEEECCCCCHHCCCCCCCCCCCCHHHHHHHHCCCCCCEEEECCCCCCHHHHHHH
LDAVAFVSAFFRQSKPVAAICHGPWLIVEAGAAKGRKLTSYSSLRTDIQNAGGDWVDEEV
HHHHHHHHHHHHCCCCEEEEECCCEEEEECCCCCCCEECHHHHHHHHHHHCCCCCCCCEE
VVDNGLITSRSPDDLPAFTARIIEEFSA
EECCCEECCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969503; 9384377; 9298659 [H]