| Definition | Hyphomonas neptunium ATCC 15444 chromosome, complete genome. |
|---|---|
| Accession | NC_008358 |
| Length | 3,705,021 |
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The map label for this gene is dsbD [H]
Identifier: 114799507
GI number: 114799507
Start: 3334570
End: 3336636
Strand: Reverse
Name: dsbD [H]
Synonym: HNE_3155
Alternate gene names: 114799507
Gene position: 3336636-3334570 (Counterclockwise)
Preceding gene: 114800476
Following gene: 114797215
Centisome position: 90.06
GC content: 63.96
Gene sequence:
>2067_bases ATGGACGAGCGCCGGGCTGAGGCGGAGCTGATTGCCGATCGCGTCAGTGTGGCGCCTGGCGACACATTTTATGCCGCTCT CAAAATGACAATGGATGAGGGCTGGCACGTTTACTGGCAGAATGCCGGGGATGCGGGTCTGCCACCCCGGCTGATACTGG AAGAGGGAACGAGCCTCCCCGAGGACGCTGTTGGCGCGTTTCTCTGGCCCCTGCCGCATCTGATCCCCGTCGTTGAAGGC GAGATCATGGATTATGGCTATGATGACGAGGTCATCTTCGCCTTTCCGGTCACTGTGCCGGAGGATGCCAGCGGTGAAGT CCGGCTTGTGGCTGAAGCTGATTACCTGATCTGCGAATCCATCTGCATTCCCGAAACGGCGGATGTTTCGTTGACGCTGC CCGTCGGCGCGCCGATCGAGAATGCGGTTGCGGGCGCAGAAATCGGCAAATGGATTGCCCGTGTACCGGTAGATTTCGCC GGCGAAGCGCGGATTGATGACGCCGCTGAACCCTGGACCCTGTCGCTGCGCCAGCCGGGCGGTTTTCCCGAAGGCGCGCA GATCCGTTTCTTTCCGTTCAAGCATGAAATCAGCCACCCGGCGGCCCAGCCCCAGAAAGCTGGCGCTGAGGGTGCAAGTC TCAGCCTGACGCCGGACCGGGCGGGCAGCATCGCAGAGACGCTGGATGGCGTAATCCGGATCGATGTGCCGGGCGCCGAG CCTGTGGGCTACGAAATCTCGGCAAGCCGCGGTGAAGCGTTTGCAGGCACGGCCGACCGGAATGTGCAATCTGCGCTTCC TGGCACAGGCGCAGGGGCGCCCGATGGAGCCGGCGACGGAGCCGCGCTTGGCTGGCAGCGAATTGCAACGCTTGCCTTCT TCGCGCTCATCGGCGGCATCATTCTCAATCTCATGCCCTGCGTGCTGCCGGTGCTGTCGATGAAAGCCATCGGTATGGTG CAGGCCGCCTCGACGGGCCATGCAGGTGAACTCAAATCGCACGGGCTCTGGTATACGGGCGGTGTGCTGGTGTCTTTCCT TGCGCTGGCGGGCGCGCTGCTGGCGGTGCGCCAGGCAACGGGATCGGCAACGCTTGGCTTCCAGCTGCAACATGCGCCCA CGGTCGCCATCCTCACCCTCGTCATGTTTGCTGTCGGCCTCTGGCTGATGGGCTATTTTGAGCTTGGGAGCTCTGTCCAG AATCTGGGCGGCAGCCTCGCCAATCGCAGCGGCGCGGCGGGCGCTTTCTTTACCGGCATTCTTGCCGCCGTGGTGGGCGC GCCCTGTGTCGGGCCGTTCCTCGGCGCGGCTTTGGGCGCCGTCATCGGCCAGCCGGCCCCGGCCGTGATCGCCGTGTTCC TCGCCATGGGCTTTGGCATGGCGCTGCCTTTCCTGATCCTCAGCTTCGTGCCGGGCCTGCACCGCATACTGCCCAAGCCC GGCAAATGGATGGACACGCTGAAACAGGCGTTCGCCTTCCCGATGTTCCTGACGGCGGCCTGGCTTCTCTCGGTTGTTGC CGGTCTTGCAGGGGCAGGGGCGGTCGGGTGGACGCTTGCGGGGGCCACGACGCTGGTATTTGCCATCTGGCTTGGCCGTC AGGGCGGCGCGGTGCGCAAGGGCGTGGCCGCTGTTGCGCTGGGCGCAGCGTTCATCTATCCGGCTGTTCAGGCGAATGTG CCCGATACCTCTGTTGCCGGCAGCAGCGAAGCGGCCTTCACCGGCGCCTATGGCGAAGCTGCCTGGAGCCCGGAAACGGT CGAGGCGATGCTGGCCGATGGCCGCCCCGTGTTCGTGGACTTCACGGCCAGCTGGTGCGCGAGCTGTCAGGTCAACAAGC TGACAACGCTGAAGACCCGCAAGGTGCAGGACGCCTTCAAGAGTGCCAATGTGGCCTTCCTGGTGGCGGACTTTACCCAG AAAGACCCGATGATTGCTGAGGAACTGAAACTGCGCGCGCGCGCCGGTGTGCCGATGTATCTCTGGTATCCGGCCGGGGC GAGCGAGCCGCAGATACTGCCGGAACTTCTCACTCAAGAACTTGTCATTGGACTTGTCGAAGGCTGA
Upstream 100 bases:
>100_bases GAGAAGTCTGACGGAGCGGCTGCAGATGACAGGGTTTTTCCGGCGTATTGCCATGGCCGCAATCAGCCTTTCGGCGCTTG CAGGGCTTGGCCATGCGCAG
Downstream 100 bases:
>100_bases CAGGCCTATACTTTCTGACACTGAAAATATTCGAGACAGGAGACGACGATGATACTTTCCCGCCGCCACTTGAGCCTTGC TGCAGGGATGGCCGCAGCCG
Product: DsbD family thioredoxin
Products: NA
Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]
Number of amino acids: Translated: 688; Mature: 688
Protein sequence:
>688_residues MDERRAEAELIADRVSVAPGDTFYAALKMTMDEGWHVYWQNAGDAGLPPRLILEEGTSLPEDAVGAFLWPLPHLIPVVEG EIMDYGYDDEVIFAFPVTVPEDASGEVRLVAEADYLICESICIPETADVSLTLPVGAPIENAVAGAEIGKWIARVPVDFA GEARIDDAAEPWTLSLRQPGGFPEGAQIRFFPFKHEISHPAAQPQKAGAEGASLSLTPDRAGSIAETLDGVIRIDVPGAE PVGYEISASRGEAFAGTADRNVQSALPGTGAGAPDGAGDGAALGWQRIATLAFFALIGGIILNLMPCVLPVLSMKAIGMV QAASTGHAGELKSHGLWYTGGVLVSFLALAGALLAVRQATGSATLGFQLQHAPTVAILTLVMFAVGLWLMGYFELGSSVQ NLGGSLANRSGAAGAFFTGILAAVVGAPCVGPFLGAALGAVIGQPAPAVIAVFLAMGFGMALPFLILSFVPGLHRILPKP GKWMDTLKQAFAFPMFLTAAWLLSVVAGLAGAGAVGWTLAGATTLVFAIWLGRQGGAVRKGVAAVALGAAFIYPAVQANV PDTSVAGSSEAAFTGAYGEAAWSPETVEAMLADGRPVFVDFTASWCASCQVNKLTTLKTRKVQDAFKSANVAFLVADFTQ KDPMIAEELKLRARAGVPMYLWYPAGASEPQILPELLTQELVIGLVEG
Sequences:
>Translated_688_residues MDERRAEAELIADRVSVAPGDTFYAALKMTMDEGWHVYWQNAGDAGLPPRLILEEGTSLPEDAVGAFLWPLPHLIPVVEG EIMDYGYDDEVIFAFPVTVPEDASGEVRLVAEADYLICESICIPETADVSLTLPVGAPIENAVAGAEIGKWIARVPVDFA GEARIDDAAEPWTLSLRQPGGFPEGAQIRFFPFKHEISHPAAQPQKAGAEGASLSLTPDRAGSIAETLDGVIRIDVPGAE PVGYEISASRGEAFAGTADRNVQSALPGTGAGAPDGAGDGAALGWQRIATLAFFALIGGIILNLMPCVLPVLSMKAIGMV QAASTGHAGELKSHGLWYTGGVLVSFLALAGALLAVRQATGSATLGFQLQHAPTVAILTLVMFAVGLWLMGYFELGSSVQ NLGGSLANRSGAAGAFFTGILAAVVGAPCVGPFLGAALGAVIGQPAPAVIAVFLAMGFGMALPFLILSFVPGLHRILPKP GKWMDTLKQAFAFPMFLTAAWLLSVVAGLAGAGAVGWTLAGATTLVFAIWLGRQGGAVRKGVAAVALGAAFIYPAVQANV PDTSVAGSSEAAFTGAYGEAAWSPETVEAMLADGRPVFVDFTASWCASCQVNKLTTLKTRKVQDAFKSANVAFLVADFTQ KDPMIAEELKLRARAGVPMYLWYPAGASEPQILPELLTQELVIGLVEG >Mature_688_residues MDERRAEAELIADRVSVAPGDTFYAALKMTMDEGWHVYWQNAGDAGLPPRLILEEGTSLPEDAVGAFLWPLPHLIPVVEG EIMDYGYDDEVIFAFPVTVPEDASGEVRLVAEADYLICESICIPETADVSLTLPVGAPIENAVAGAEIGKWIARVPVDFA GEARIDDAAEPWTLSLRQPGGFPEGAQIRFFPFKHEISHPAAQPQKAGAEGASLSLTPDRAGSIAETLDGVIRIDVPGAE PVGYEISASRGEAFAGTADRNVQSALPGTGAGAPDGAGDGAALGWQRIATLAFFALIGGIILNLMPCVLPVLSMKAIGMV QAASTGHAGELKSHGLWYTGGVLVSFLALAGALLAVRQATGSATLGFQLQHAPTVAILTLVMFAVGLWLMGYFELGSSVQ NLGGSLANRSGAAGAFFTGILAAVVGAPCVGPFLGAALGAVIGQPAPAVIAVFLAMGFGMALPFLILSFVPGLHRILPKP GKWMDTLKQAFAFPMFLTAAWLLSVVAGLAGAGAVGWTLAGATTLVFAIWLGRQGGAVRKGVAAVALGAAFIYPAVQANV PDTSVAGSSEAAFTGAYGEAAWSPETVEAMLADGRPVFVDFTASWCASCQVNKLTTLKTRKVQDAFKSANVAFLVADFTQ KDPMIAEELKLRARAGVPMYLWYPAGASEPQILPELLTQELVIGLVEG
Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a
COG id: COG4232
COG function: function code OC; Thiol:disulfide interchange protein
Gene ontology:
Cell location: Cell inner membrane; Multi-pass membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 thioredoxin domain [H]
Homologues:
Organism=Escherichia coli, GI1790578, Length=400, Percent_Identity=28.75, Blast_Score=84, Evalue=2e-17,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003834 - InterPro: IPR022910 - InterPro: IPR005746 - InterPro: IPR017936 - InterPro: IPR012336 - InterPro: IPR017937 - InterPro: IPR013766 - InterPro: IPR012335 [H]
Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]
EC number: =1.8.1.8 [H]
Molecular weight: Translated: 71571; Mature: 71571
Theoretical pI: Translated: 4.42; Mature: 4.42
Prosite motif: PS00194 THIOREDOXIN
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.9 %Cys (Translated Protein) 2.3 %Met (Translated Protein) 3.2 %Cys+Met (Translated Protein) 0.9 %Cys (Mature Protein) 2.3 %Met (Mature Protein) 3.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MDERRAEAELIADRVSVAPGDTFYAALKMTMDEGWHVYWQNAGDAGLPPRLILEEGTSLP CCCHHHHHHHHHHHHCCCCCCCEEEHHEEECCCCCEEEEECCCCCCCCCHHEECCCCCCC EDAVGAFLWPLPHLIPVVEGEIMDYGYDDEVIFAFPVTVPEDASGEVRLVAEADYLICES HHHHHHHHHHHHHHHHHHCCHHCCCCCCCCEEEEEECCCCCCCCCCEEEEEECCCHHHHC ICIPETADVSLTLPVGAPIENAVAGAEIGKWIARVPVDFAGEARIDDAAEPWTLSLRQPG CCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCC GFPEGAQIRFFPFKHEISHPAAQPQKAGAEGASLSLTPDRAGSIAETLDGVIRIDVPGAE CCCCCCEEEEEECHHHHCCCCCCCHHCCCCCCEEEECCCCCCCHHHHCCCEEEEECCCCC PVGYEISASRGEAFAGTADRNVQSALPGTGAGAPDGAGDGAALGWQRIATLAFFALIGGI CCCEEEECCCCCEECCCCCCCHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH ILNLMPCVLPVLSMKAIGMVQAASTGHAGELKSHGLWYTGGVLVSFLALAGALLAVRQAT HHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCC GSATLGFQLQHAPTVAILTLVMFAVGLWLMGYFELGSSVQNLGGSLANRSGAAGAFFTGI CCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCHHHHHHH LAAVVGAPCVGPFLGAALGAVIGQPAPAVIAVFLAMGFGMALPFLILSFVPGLHRILPKP HHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC GKWMDTLKQAFAFPMFLTAAWLLSVVAGLAGAGAVGWTLAGATTLVFAIWLGRQGGAVRK CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHH GVAAVALGAAFIYPAVQANVPDTSVAGSSEAAFTGAYGEAAWSPETVEAMLADGRPVFVD HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCCCCCCHHHHHHHHCCCCEEEEE FTASWCASCQVNKLTTLKTRKVQDAFKSANVAFLVADFTQKDPMIAEELKLRARAGVPMY ECHHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCEE LWYPAGASEPQILPELLTQELVIGLVEG EEECCCCCCCHHHHHHHHHHHHHHHCCC >Mature Secondary Structure MDERRAEAELIADRVSVAPGDTFYAALKMTMDEGWHVYWQNAGDAGLPPRLILEEGTSLP CCCHHHHHHHHHHHHCCCCCCCEEEHHEEECCCCCEEEEECCCCCCCCCHHEECCCCCCC EDAVGAFLWPLPHLIPVVEGEIMDYGYDDEVIFAFPVTVPEDASGEVRLVAEADYLICES HHHHHHHHHHHHHHHHHHCCHHCCCCCCCCEEEEEECCCCCCCCCCEEEEEECCCHHHHC ICIPETADVSLTLPVGAPIENAVAGAEIGKWIARVPVDFAGEARIDDAAEPWTLSLRQPG CCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCC GFPEGAQIRFFPFKHEISHPAAQPQKAGAEGASLSLTPDRAGSIAETLDGVIRIDVPGAE CCCCCCEEEEEECHHHHCCCCCCCHHCCCCCCEEEECCCCCCCHHHHCCCEEEEECCCCC PVGYEISASRGEAFAGTADRNVQSALPGTGAGAPDGAGDGAALGWQRIATLAFFALIGGI CCCEEEECCCCCEECCCCCCCHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH ILNLMPCVLPVLSMKAIGMVQAASTGHAGELKSHGLWYTGGVLVSFLALAGALLAVRQAT HHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCC GSATLGFQLQHAPTVAILTLVMFAVGLWLMGYFELGSSVQNLGGSLANRSGAAGAFFTGI CCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCHHHHHHH LAAVVGAPCVGPFLGAALGAVIGQPAPAVIAVFLAMGFGMALPFLILSFVPGLHRILPKP HHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC GKWMDTLKQAFAFPMFLTAAWLLSVVAGLAGAGAVGWTLAGATTLVFAIWLGRQGGAVRK CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHH GVAAVALGAAFIYPAVQANVPDTSVAGSSEAAFTGAYGEAAWSPETVEAMLADGRPVFVD HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCCCCCCHHHHHHHHCCCCEEEEE FTASWCASCQVNKLTTLKTRKVQDAFKSANVAFLVADFTQKDPMIAEELKLRARAGVPMY ECHHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCEE LWYPAGASEPQILPELLTQELVIGLVEG EEECCCCCCCHHHHHHHHHHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 10952301 [H]