Click here to switch to the map view.

The map label for this gene is hit [H]

Identifier: 114799198

GI number: 114799198

Start: 2391123

End: 2391557

Strand: Direct

Name: hit [H]

Synonym: HNE_2290

Alternate gene names: 114799198

Gene position: 2391123-2391557 (Clockwise)

Preceding gene: 114799871

Following gene: 114798765

Centisome position: 64.54

GC content: 60.92

Gene sequence:

>435_bases
ATGACCCTTCACGCAGCCTACGACCCAGACAACATCTTTGCGAAAATCCTGCGCGGCGACATGCCGAGCCTGAAAGTGTT
CGAGGATGATGTTGCCCTCGCCTTCATGGACGTGTTCCCGCAGAGCGAAGGCCATACGCTGGTGATCCCCAAAGGCATCC
AGGCGCGCAACTTCCTCGACATTCCACCCGATTATCTGGGCAGCTACATGCTGCGCGTGCAGCGGATCGCCAAGGCAGTG
GAGTGGGGCCTGAAGCCTGACGGGCTGCGTGTCATGCAGTTCAACGGCGCCTCTGCGGGGCAGACGGTCTTCCACCTGCA
TTTCCATGTCATTCCGGCCTGGGACGGCAAGGAACTTGGCCGCCACGGAACCGGCACGATGGCCAAGCCCGAGGAGCTGG
AGCCGATTGCAGCAAAGATACGGGCAGCGGTTTGA

Upstream 100 bases:

>100_bases
ACGCTGTCTCCGATTACCTTGAGCGCGAGCGCGCAGCGGTTGACGAAGACATGAACTATTTGCGAGATCGAACTCCGTTC
AGGAAAGAATAGTAGATCAC

Downstream 100 bases:

>100_bases
GGCTGTCTTAAGCCCCCTCGCCCCTCCGGGGAGAGGGGGCTTAAGGGGGGAGACGGGTCAAATGCCCAGCTTAGCCTTCA
GAATATCGTTCACAGCCTTC

Product: histidine triad family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 144; Mature: 143

Protein sequence:

>144_residues
MTLHAAYDPDNIFAKILRGDMPSLKVFEDDVALAFMDVFPQSEGHTLVIPKGIQARNFLDIPPDYLGSYMLRVQRIAKAV
EWGLKPDGLRVMQFNGASAGQTVFHLHFHVIPAWDGKELGRHGTGTMAKPEELEPIAAKIRAAV

Sequences:

>Translated_144_residues
MTLHAAYDPDNIFAKILRGDMPSLKVFEDDVALAFMDVFPQSEGHTLVIPKGIQARNFLDIPPDYLGSYMLRVQRIAKAV
EWGLKPDGLRVMQFNGASAGQTVFHLHFHVIPAWDGKELGRHGTGTMAKPEELEPIAAKIRAAV
>Mature_143_residues
TLHAAYDPDNIFAKILRGDMPSLKVFEDDVALAFMDVFPQSEGHTLVIPKGIQARNFLDIPPDYLGSYMLRVQRIAKAVE
WGLKPDGLRVMQFNGASAGQTVFHLHFHVIPAWDGKELGRHGTGTMAKPEELEPIAAKIRAAV

Specific function: Unknown

COG id: COG0537

COG function: function code FGR; Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HIT domain [H]

Homologues:

Organism=Homo sapiens, GI4885413, Length=104, Percent_Identity=39.4230769230769, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17506713, Length=104, Percent_Identity=42.3076923076923, Blast_Score=76, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6320078, Length=117, Percent_Identity=41.8803418803419, Blast_Score=87, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24581222, Length=109, Percent_Identity=44.954128440367, Blast_Score=77, Evalue=4e-15,
Organism=Drosophila melanogaster, GI28574010, Length=109, Percent_Identity=44.954128440367, Blast_Score=77, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011146
- InterPro:   IPR011151
- InterPro:   IPR019808
- InterPro:   IPR001310 [H]

Pfam domain/function: PF01230 HIT [H]

EC number: NA

Molecular weight: Translated: 15952; Mature: 15820

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS51084 HIT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLHAAYDPDNIFAKILRGDMPSLKVFEDDVALAFMDVFPQSEGHTLVIPKGIQARNFLD
CEEECCCCHHHHHHHHHHCCCCCCEEECCHHHHHHHHHCCCCCCCEEEEECCCCCCCCCC
IPPDYLGSYMLRVQRIAKAVEWGLKPDGLRVMQFNGASAGQTVFHLHFHVIPAWDGKELG
CCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCEEEEEEEEEEECCCCHHHC
RHGTGTMAKPEELEPIAAKIRAAV
CCCCCCCCCCHHCCHHHHHHHHCC
>Mature Secondary Structure 
TLHAAYDPDNIFAKILRGDMPSLKVFEDDVALAFMDVFPQSEGHTLVIPKGIQARNFLD
EEECCCCHHHHHHHHHHCCCCCCEEECCHHHHHHHHHCCCCCCCEEEEECCCCCCCCCC
IPPDYLGSYMLRVQRIAKAVEWGLKPDGLRVMQFNGASAGQTVFHLHFHVIPAWDGKELG
CCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCEEEEEEEEEEECCCCHHHC
RHGTGTMAKPEELEPIAAKIRAAV
CCCCCCCCCCHHCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]