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The map label for this gene is argB

Identifier: 114798995

GI number: 114798995

Start: 416012

End: 416905

Strand: Direct

Name: argB

Synonym: HNE_0418

Alternate gene names: 114798995

Gene position: 416012-416905 (Clockwise)

Preceding gene: 114799999

Following gene: 114797989

Centisome position: 11.23

GC content: 63.65

Gene sequence:

>894_bases
ATGACGACCCAATCCGACGCCCAGTTCACCGCCCGCACCCTCTCAGAGGCTCTGCCCTATATCCAGCGCTATGCCGGCCA
GACCATCGTTGTGAAATACGGTGGCCATGCCATGGGGGACGCCAGCCTCGCGCTGAGTTTTGCCCGCGATGTGGTGCTGC
TGAAGGCCCTCGGCCTCAACCCGGTGATCGTGCATGGCGGCGGCCCGCAGATCGGCAAGCTGCTCGACAAGCTCGGCATC
GTTTCCGAATTCAAGGATGGCCTGCGGGTGACCGATGAAGCGACGATGGAAGTCGTCGAGATGGTCCTCTCCGGCCCGAT
CAACAAATCCATCGTCCGCGCCATCAACCAGGCCGGTGGCAAGGCAGTCGGCCTGTCGGGCGCTGACGGCAATCTTCTGC
GGGCGGAGAAAGCCACGCGCACGACGCGCGACCCCGACAGCCATATCGAACAGATCGTCGATCTCGGCTTTGTCGGCGAG
CCCAGCGAAGTCGACATCAGCGTGCTCAATGCCCTGTTGCAGGCCGATGCCGCGCTGATCCCCGTTGTGGCGCCCGTCGG
CGTCGGCGCCGATGGCGCGCGCTACAATGTGAACGCAGATACGGCCGCCGGCGCGCTGGCCGCCGCGCTGAAAGCCAGCC
GCCTGATCCTGATGACGGACGTGGCCGGCGTGCTCGACAAGCAGAAACAGCTGATCCGCGAGATCCCCGCGTCGCAGGTC
GAACTGCTGATCAAGGACGGCACAGCTGTCGGCGGTATGATACCGAAGCTTGAAACGGCGGCACAATCTGTAAATCATGG
TGTTGGGGCGGCGGTTATTCTGGATGGGCGTGCGCCGCATGCCCTGCTCATGGAGCTGTTCACCGAACATGGCGCTGGAA
CGCTGGTTTCTTAG

Upstream 100 bases:

>100_bases
TTCCGGCCAAAATCACGCCGCGGCGCGCCCGGCGCTGAACGGGATCGGCACGTAGATTAGCCGTTTCGTCTCGCCCAAAA
CCGGGTTAAGAGCCCGGCCC

Downstream 100 bases:

>100_bases
AATTGTAGTTTTGGCCATCGCCTCGCTGGCCGTCCTTCTGCTGCCCGCAGAGGCGCAGGAAGGCGAAGGCTGGAAGCTGT
GCAATCGCACGAGCTTCGTG

Product: acetylglutamate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK

Number of amino acids: Translated: 297; Mature: 296

Protein sequence:

>297_residues
MTTQSDAQFTARTLSEALPYIQRYAGQTIVVKYGGHAMGDASLALSFARDVVLLKALGLNPVIVHGGGPQIGKLLDKLGI
VSEFKDGLRVTDEATMEVVEMVLSGPINKSIVRAINQAGGKAVGLSGADGNLLRAEKATRTTRDPDSHIEQIVDLGFVGE
PSEVDISVLNALLQADAALIPVVAPVGVGADGARYNVNADTAAGALAAALKASRLILMTDVAGVLDKQKQLIREIPASQV
ELLIKDGTAVGGMIPKLETAAQSVNHGVGAAVILDGRAPHALLMELFTEHGAGTLVS

Sequences:

>Translated_297_residues
MTTQSDAQFTARTLSEALPYIQRYAGQTIVVKYGGHAMGDASLALSFARDVVLLKALGLNPVIVHGGGPQIGKLLDKLGI
VSEFKDGLRVTDEATMEVVEMVLSGPINKSIVRAINQAGGKAVGLSGADGNLLRAEKATRTTRDPDSHIEQIVDLGFVGE
PSEVDISVLNALLQADAALIPVVAPVGVGADGARYNVNADTAAGALAAALKASRLILMTDVAGVLDKQKQLIREIPASQV
ELLIKDGTAVGGMIPKLETAAQSVNHGVGAAVILDGRAPHALLMELFTEHGAGTLVS
>Mature_296_residues
TTQSDAQFTARTLSEALPYIQRYAGQTIVVKYGGHAMGDASLALSFARDVVLLKALGLNPVIVHGGGPQIGKLLDKLGIV
SEFKDGLRVTDEATMEVVEMVLSGPINKSIVRAINQAGGKAVGLSGADGNLLRAEKATRTTRDPDSHIEQIVDLGFVGEP
SEVDISVLNALLQADAALIPVVAPVGVGADGARYNVNADTAAGALAAALKASRLILMTDVAGVLDKQKQLIREIPASQVE
LLIKDGTAVGGMIPKLETAAQSVNHGVGAAVILDGRAPHALLMELFTEHGAGTLVS

Specific function: Arginine biosynthesis; first step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family

Homologues:

Organism=Escherichia coli, GI1789181, Length=290, Percent_Identity=25.5172413793103, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI145693208, Length=199, Percent_Identity=36.1809045226131, Blast_Score=83, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6320913, Length=295, Percent_Identity=26.4406779661017, Blast_Score=81, Evalue=2e-16,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ARGB_HYPNA (Q0C545)

Other databases:

- EMBL:   CP000158
- RefSeq:   YP_759148.1
- ProteinModelPortal:   Q0C545
- SMR:   Q0C545
- STRING:   Q0C545
- GeneID:   4288427
- GenomeReviews:   CP000158_GR
- KEGG:   hne:HNE_0418
- NMPDR:   fig|228405.5.peg.411
- TIGR:   HNE_0418
- eggNOG:   COG0548
- HOGENOM:   HBG497643
- OMA:   DGEYEIN
- PhylomeDB:   Q0C545
- ProtClustDB:   CLSK2531923
- BioCyc:   HNEP81032:HNE_0418-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00082_B
- InterPro:   IPR004662
- InterPro:   IPR001048
- InterPro:   IPR001057
- Gene3D:   G3DSA:3.40.1160.10
- PIRSF:   PIRSF000728
- PRINTS:   PR00474
- TIGRFAMs:   TIGR00761

Pfam domain/function: PF00696 AA_kinase; SSF53633 Aa_kinase

EC number: =2.7.2.8

Molecular weight: Translated: 30722; Mature: 30591

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: NA

Important sites: BINDING 89-89 BINDING 196-196

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTQSDAQFTARTLSEALPYIQRYAGQTIVVKYGGHAMGDASLALSFARDVVLLKALGLN
CCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCC
PVIVHGGGPQIGKLLDKLGIVSEFKDGLRVTDEATMEVVEMVLSGPINKSIVRAINQAGG
EEEEECCCCHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCC
KAVGLSGADGNLLRAEKATRTTRDPDSHIEQIVDLGFVGEPSEVDISVLNALLQADAALI
CEEECCCCCCCEEEHHHHHCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHH
PVVAPVGVGADGARYNVNADTAAGALAAALKASRLILMTDVAGVLDKQKQLIREIPASQV
HHHHCCCCCCCCCEEECCCHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHCCHHHH
ELLIKDGTAVGGMIPKLETAAQSVNHGVGAAVILDGRAPHALLMELFTEHGAGTLVS
EEEEECCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TTQSDAQFTARTLSEALPYIQRYAGQTIVVKYGGHAMGDASLALSFARDVVLLKALGLN
CCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCC
PVIVHGGGPQIGKLLDKLGIVSEFKDGLRVTDEATMEVVEMVLSGPINKSIVRAINQAGG
EEEEECCCCHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCC
KAVGLSGADGNLLRAEKATRTTRDPDSHIEQIVDLGFVGEPSEVDISVLNALLQADAALI
CEEECCCCCCCEEEHHHHHCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHH
PVVAPVGVGADGARYNVNADTAAGALAAALKASRLILMTDVAGVLDKQKQLIREIPASQV
HHHHCCCCCCCCCEEECCCHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHCCHHHH
ELLIKDGTAVGGMIPKLETAAQSVNHGVGAAVILDGRAPHALLMELFTEHGAGTLVS
EEEEECCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA