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The map label for this gene is fur [H]

Identifier: 114798658

GI number: 114798658

Start: 522238

End: 522657

Strand: Direct

Name: fur [H]

Synonym: HNE_0528

Alternate gene names: 114798658

Gene position: 522238-522657 (Clockwise)

Preceding gene: 114798860

Following gene: 114799592

Centisome position: 14.1

GC content: 58.57

Gene sequence:

>420_bases
ATGGACAGACTAGAAAAACTCTGCATTGAGAAGGGCCTCCGCATGACGGAGCCTCGGCGGATCATTGCCCGCGTGCTTTC
GGTGGCCGATGACCATCCTGACGCCGAAGAACTGCACCGGCGCGCCAATTCGCTGGACGCCTCGATTTCGCTCGCCACGG
TCTATCGGACGGTCAAACTGTTCGAGGACGCCGGCATCATCCAGGCGCATGACTTCCGTGATGGCCGCGCCCGGTATGAA
GAAATGCCGGCCGAGCACCACGACCATCTGATCGACATCAAGACAGGGCAGGTGGTGGAGTTCCATTCCGAAGAGATCGA
AAAGCTTCAGGAAGAAATCGCCCGCAAGCTTGGCTACCGGCTGGTCGATCACCGGCTGGAGCTTTACGGCGTGCCGCTCA
ACGAAAAAGACAAATCCTGA

Upstream 100 bases:

>100_bases
CTCGCCTGGTCCCGGACGCTGGATTTCTTCGGCAAGCACCTGCGCGGCAGCTGACAAGGTTGAACTGGACTTTCCCGCTG
GGCGAGGGCATTTAGGGACC

Downstream 100 bases:

>100_bases
CGTCAAGGCCGGGCGCCATCCAGGCGCCGCCAGAAAGCAAACGGCCCCGTCAGACTGACGGGGCCGTTTTCGTTTCGCGG
AAAGGCGCGTGCTTAGAACT

Product: ferric uptake regulation protein

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 139; Mature: 139

Protein sequence:

>139_residues
MDRLEKLCIEKGLRMTEPRRIIARVLSVADDHPDAEELHRRANSLDASISLATVYRTVKLFEDAGIIQAHDFRDGRARYE
EMPAEHHDHLIDIKTGQVVEFHSEEIEKLQEEIARKLGYRLVDHRLELYGVPLNEKDKS

Sequences:

>Translated_139_residues
MDRLEKLCIEKGLRMTEPRRIIARVLSVADDHPDAEELHRRANSLDASISLATVYRTVKLFEDAGIIQAHDFRDGRARYE
EMPAEHHDHLIDIKTGQVVEFHSEEIEKLQEEIARKLGYRLVDHRLELYGVPLNEKDKS
>Mature_139_residues
MDRLEKLCIEKGLRMTEPRRIIARVLSVADDHPDAEELHRRANSLDASISLATVYRTVKLFEDAGIIQAHDFRDGRARYE
EMPAEHHDHLIDIKTGQVVEFHSEEIEKLQEEIARKLGYRLVDHRLELYGVPLNEKDKS

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=120, Percent_Identity=45.8333333333333, Blast_Score=103, Evalue=6e-24,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 16169; Mature: 16169

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRLEKLCIEKGLRMTEPRRIIARVLSVADDHPDAEELHRRANSLDASISLATVYRTVKL
CCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHH
FEDAGIIQAHDFRDGRARYEEMPAEHHDHLIDIKTGQVVEFHSEEIEKLQEEIARKLGYR
HHCCCCEEECCCCCHHHHHHHCCHHHCCCEEECCCCCEEHHHHHHHHHHHHHHHHHHHHH
LVDHRLELYGVPLNEKDKS
HHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MDRLEKLCIEKGLRMTEPRRIIARVLSVADDHPDAEELHRRANSLDASISLATVYRTVKL
CCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHH
FEDAGIIQAHDFRDGRARYEEMPAEHHDHLIDIKTGQVVEFHSEEIEKLQEEIARKLGYR
HHCCCCEEECCCCCHHHHHHHCCHHHCCCEEECCCCCEEHHHHHHHHHHHHHHHHHHHHH
LVDHRLELYGVPLNEKDKS
HHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9835040 [H]