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The map label for this gene is kdgR [H]

Identifier: 114798458

GI number: 114798458

Start: 2216085

End: 2216861

Strand: Direct

Name: kdgR [H]

Synonym: HNE_2131

Alternate gene names: 114798458

Gene position: 2216085-2216861 (Clockwise)

Preceding gene: 114797656

Following gene: 114799021

Centisome position: 59.81

GC content: 61.52

Gene sequence:

>777_bases
ATGACGGAAGCCCCTTATAAAGCACCCGCCCTGGAAAAGGGCCTCGATATTCTCGAATGCCTTGCCAGCCTGCGCACGCC
TCAATCCATTTCCGACATTGCACGGAACATCGGCCGCTCCCGCAGCGAGATTTACCGCATGGTCGTCGTACTGGAAATGC
GCGGCTATGTGGAGCGCACCGAAGACCCCGAAAAACTGCAACTATCGAACCGCCTGTTTGAAGTGGGCATGCGCTCGCCG
CCCAAGATGGACCTGCATGAAGCCGCCCTGCCGGAGATGTCGGCGCTCGCCTCGCAGATGATGCAATCCATCCAGCTCGC
CGTCGTCAGCTCTGAACAGATTGTCGTCATTGCACGGACTGAAAGCCCCGATGATGTCGGCTTCAGCGTGCGCCTCGGCC
ATCGCCGATCCATCATGAAATCGGCTTCTGGTCTGGTCCTGTTCGCATTCGCCTCGCCCATGCAGGAGGCAAAAATGCTG
GAAGACCTCAAAGCCACCGGCGCAACGCCCGCCGAGCTGGAAGCGCTCCATGCCCAGACGCAGCAAGTCCGCGAAACCGG
ATTCGTCTGTATGCCTTCCCGGATGGTCGACGGTGTGACCGACATTGGCGCCCCCATCTTCGATGCGGCCAGCAGCGGCG
CCATCGCCAGCCTGACTGTACCTTTCGTCGTCACCCGGCGCGCGAAGGTGTCCCTGGACGAGGCGCCTCACCTTGTTGCG
GATGCCGCCCGGCGCATTTCCGTAACGCTGGGCCACGCGGCATCTGCGGGACGTTAA

Upstream 100 bases:

>100_bases
TAAAAAAACTGAGCGGCCAACCAGAGTCACCTGTGGATTAACGCAGGTTTTTGGTTCATATATAAAACCGCTCAAATCAA
TCTGAGGACACTGGCAGTCG

Downstream 100 bases:

>100_bases
TCGTGATGGAAGACCTCTTCCATCGGCGCCCACCACTCTCCTTCCGCCACTGACTCCAGCGGGCTCTGACAGGGATCGGT
CAACGCCCACCATCGCTGCG

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:

>258_residues
MTEAPYKAPALEKGLDILECLASLRTPQSISDIARNIGRSRSEIYRMVVVLEMRGYVERTEDPEKLQLSNRLFEVGMRSP
PKMDLHEAALPEMSALASQMMQSIQLAVVSSEQIVVIARTESPDDVGFSVRLGHRRSIMKSASGLVLFAFASPMQEAKML
EDLKATGATPAELEALHAQTQQVRETGFVCMPSRMVDGVTDIGAPIFDAASSGAIASLTVPFVVTRRAKVSLDEAPHLVA
DAARRISVTLGHAASAGR

Sequences:

>Translated_258_residues
MTEAPYKAPALEKGLDILECLASLRTPQSISDIARNIGRSRSEIYRMVVVLEMRGYVERTEDPEKLQLSNRLFEVGMRSP
PKMDLHEAALPEMSALASQMMQSIQLAVVSSEQIVVIARTESPDDVGFSVRLGHRRSIMKSASGLVLFAFASPMQEAKML
EDLKATGATPAELEALHAQTQQVRETGFVCMPSRMVDGVTDIGAPIFDAASSGAIASLTVPFVVTRRAKVSLDEAPHLVA
DAARRISVTLGHAASAGR
>Mature_257_residues
TEAPYKAPALEKGLDILECLASLRTPQSISDIARNIGRSRSEIYRMVVVLEMRGYVERTEDPEKLQLSNRLFEVGMRSPP
KMDLHEAALPEMSALASQMMQSIQLAVVSSEQIVVIARTESPDDVGFSVRLGHRRSIMKSASGLVLFAFASPMQEAKMLE
DLKATGATPAELEALHAQTQQVRETGFVCMPSRMVDGVTDIGAPIFDAASSGAIASLTVPFVVTRRAKVSLDEAPHLVAD
AARRISVTLGHAASAGR

Specific function: Transcriptional repressor of genes involved in pectinolysis and in pectinase secretion. Controls all the genes involved in pectin catabolism, including the pel genes encoding pectate lyases, kdgT which encodes the 2-keto-3-deoxygluconate transport system

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1788131, Length=255, Percent_Identity=27.843137254902, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1786468, Length=248, Percent_Identity=25.4032258064516, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1786715, Length=253, Percent_Identity=25.6916996047431, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1788581, Length=253, Percent_Identity=25.6916996047431, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 27891; Mature: 27759

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEAPYKAPALEKGLDILECLASLRTPQSISDIARNIGRSRSEIYRMVVVLEMRGYVERT
CCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCC
EDPEKLQLSNRLFEVGMRSPPKMDLHEAALPEMSALASQMMQSIQLAVVSSEQIVVIART
CCHHHHHHHHHHHHHCCCCCCCCCHHHHHCHHHHHHHHHHHHHHHHHEECCCEEEEEEEC
ESPDDVGFSVRLGHRRSIMKSASGLVLFAFASPMQEAKMLEDLKATGATPAELEALHAQT
CCCCCCCEEEEECHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHH
QQVRETGFVCMPSRMVDGVTDIGAPIFDAASSGAIASLTVPFVVTRRAKVSLDEAPHLVA
HHHHHCCCEEECHHHHCCHHHCCCHHHHCCCCCCEEEEEHHHHEECCHHCCCCCCCHHHH
DAARRISVTLGHAASAGR
HHHHHEEEEECCCCCCCC
>Mature Secondary Structure 
TEAPYKAPALEKGLDILECLASLRTPQSISDIARNIGRSRSEIYRMVVVLEMRGYVERT
CCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCC
EDPEKLQLSNRLFEVGMRSPPKMDLHEAALPEMSALASQMMQSIQLAVVSSEQIVVIART
CCHHHHHHHHHHHHHCCCCCCCCCHHHHHCHHHHHHHHHHHHHHHHHEECCCEEEEEEEC
ESPDDVGFSVRLGHRRSIMKSASGLVLFAFASPMQEAKMLEDLKATGATPAELEALHAQT
CCCCCCCEEEEECHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHH
QQVRETGFVCMPSRMVDGVTDIGAPIFDAASSGAIASLTVPFVVTRRAKVSLDEAPHLVA
HHHHHCCCEEECHHHHCCHHHCCCHHHHCCCCCCEEEEEHHHHEECCHHCCCCCCCHHHH
DAARRISVTLGHAASAGR
HHHHHEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1840643; 1545709 [H]